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1. 发明申请

WO2017065809A1 SYSTEMS AND METHODS FOR INTRA-SURGICAL MONITORING OF EVOKED RESPONSES THAT OCCUR DURING AN ELECTRODE LEAD INSERTION PROCEDURE 审中-公开
标题翻译：用于在电极导线插入程序期间进行诱发反应的手术中监测的系统和方法
公开(公告)号：WO2017065809A1
公开(公告)日：2017-04-20
申请号：PCT/US2015/058879
申请日：2015-11-03
申请人： ADVANCED BIONICS AG , KOKA, Kanthaiah , LITVAK, Leonid M.
发明人： KOKA, Kanthaiah , LITVAK, Leonid M.
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0541 , A61N1/36036
摘要： An exemplary monitoring system 1) receives a user input command to begin monitoring evoked responses that occur in response to acoustic stimulation during an insertion procedure in which a lead that is communicatively coupled to a cochlear implant is inserted into a cochlea of a patient, the lead having an array of intracochlear electrodes and an extracochlear electrode, the extracochlear electrode physically and communicatively coupled to a probe that is also communicatively coupled to the monitoring system, 2) directs, in response to the user input command, the cochlear implant to short an intracochlear electrode with the extracochlear electrode, 3) presents the acoustic stimulation to the patient, and 4) records the evoked responses that occur in response to the acoustic stimulation by using the intracochlear electrode to detect signals representative of the evoked responses and receiving the detected signals by way of the extracochlear electrode and the probe.
摘要翻译：示例性监视系统1）接收用户输入命令以开始监视在插入过程期间响应于声刺激而发生的诱发响应，其中通信地耦合到耳蜗植入物的引线被插入患者的耳蜗，所述引线具有耳蜗内电极阵列和耳蜗外电极，所述耳蜗外电极在物理上并且通信地耦合到也通信地耦合到所述监测系统的探头，2）响应于所述用户输入命令，耳蜗植入物用耳蜗外电极使耳蜗内电极短路，3）向患者呈现声刺激，以及4）通过使用耳蜗内电极来检测响应于声刺激而发生的诱发响应，以检测代表诱发反应，并通过耳蜗外电极和探头接收检测信号。

2. 发明申请

WO2012161717A1 SYSTEMS AND METHODS FOR IMPROVING REPRESENTATION BY AN AUDITORY PROSTHESIS SYSTEM OF AUDIO SIGNALS HAVING INTERMEDIATE SOUND LEVELS 审中-公开
标题翻译：通过具有中级声级的音频信号的审计预测系统来改进表示的系统和方法
公开(公告)号：WO2012161717A1
公开(公告)日：2012-11-29
申请号：PCT/US2011/038169
申请日：2011-05-26
申请人： ADVANCED BIONICS AG , LITVAK, Leonid M. , OKUYAMA, Nobutaka , KULKARNI, Abhijit
发明人： LITVAK, Leonid M. , OKUYAMA, Nobutaka , KULKARNI, Abhijit
IPC分类号： A61N1/05
CPC分类号： H04R25/50 , A61N1/0541 , A61N1/36036 , H03G3/20
摘要： An exemplary system includes a detection facility configured to detect an input sound level of an audio signal presented to an auditory prosthesis patient; and an adaptive gain control (AGC) facility configured to 1) determine whether the detected input sound level is in a quiet region, an intermediate region, or a loud region, and 2) apply a gain to the audio signal in accordance with an AGC gain function that specifies the gain to be substantially equal to or less than a first gain threshold if the detected input sound level is in the quiet region, substantially equal to or less than a second gain threshold if the detected input sound level is in the loud region, and greater than the first and second gain thresholds if the detected input sound level is in the intermediate region. Corresponding systems and methods are also disclosed.
摘要翻译：示例性系统包括被配置为检测呈现给听觉假体患者的音频信号的输入声级的检测设备; 以及自适应增益控制（AGC）设备，其被配置为：1）确定检测到的输入声级是否在安静区域，中间区域或大声区域中，以及2）根据AGC来对音频信号应用增益增益函数，如果检测到的输入声级在安静区域中，如果检测到的输入声音水平大致等于或小于第二增益阈值，则将增益指定为基本上等于或小于第一增益阈值并且如果检测到的输入声音电平处于中间区域，则大于第一和第二增益阈值。还公开了相应的系统和方法。

3. 发明申请

WO2012150928A1 SYSTEMS FOR OPTIMIZING A COMPLIANCE VOLTAGE OF AN AUDITORY PROSTHESIS 审中-公开
标题翻译：用于优化审计报告合规电压的系统
公开(公告)号：WO2012150928A1
公开(公告)日：2012-11-08
申请号：PCT/US2011/034860
申请日：2011-05-02
申请人： ADVANCED BIONICS AG , LITVAK, Leonid M.
发明人： LITVAK, Leonid M.
IPC分类号： A61N1/36 , H04R25/00
CPC分类号： A61N1/36 , A61N1/025 , A61N1/0541 , A61N1/36036
摘要： Exemplary systems and methods for optimizing a compliance voltage of an auditory prosthesis are disclosed. Each stimulation channel formed by electrodes that are coupled to an auditory prosthesis may have an adjustable current steering range associated therewith. Each adjustable current steering range is centered about the midpoint of its respective stimulation channel and defines a range of current steering that may be used within its respective stimulation channel. A compliance voltage of an auditory prosthesis may be optimized by setting a current steering range for one or more stimulation channels to a value that results in an optimum balance between power conservation and performance of the auditory prosthesis.
摘要翻译：公开了用于优化听觉假体的顺应性电压的示例性系统和方法。由耦合到听觉假体的电极形成的每个刺激通道可以具有与之相关联的可调节的电流操舵范围。每个可调整的电流转向范围围绕其各自的刺激通道的中点居中，并且限定可在其各自的刺激通道内使用的电流转向的范围。可以通过将一个或多个刺激通道的当前转向范围设置为导致功率保持和听觉假体的性能之间的最佳平衡的值来优化听觉假体的顺应性电压。

4. 发明申请

WO2019045747A1 ELECTRODE LOCATING SYSTEMS AND METHODS FOR USE WITHIN A COCHLEAR IMPLANT PATIENT 审中-公开
公开(公告)号：WO2019045747A1
公开(公告)日：2019-03-07
申请号：PCT/US2017/049792
申请日：2017-08-31
申请人： ADVANCED BIONICS AG , KOKA, Kanthaiah , LITVAK, Leonid M.
发明人： KOKA, Kanthaiah , LITVAK, Leonid M.
IPC分类号： A61N1/36 , A61N1/05 , A61B5/06
摘要： An exemplary electrode locating system performs an excitation spread measurement by directing a first electrode to generate an electrical pulse and, in response to the generation of the electrical pulse, detecting a voltage between a second electrode and a reference that are both distinct from the first electrode. The first and second electrodes are included in a plurality of electrodes disposed on an electrode lead included within a cochlear implant system and that comprises a proximal portion configured to be coupled with a cochlear implant and a distal portion configured to be inserted into a cochlea of a patient by way of an insertion procedure. Based on the excitation spread measurement, the electrode locating system determines whether at least one of the first electrode and the second electrode is located within the cochlea. Corresponding methods are also described.

5. 发明申请

WO2019045680A1 SYSTEMS AND METHODS FOR DETECTING A SCALAR TRANSLOCATION OF AN ELECTRODE LEAD WITHIN A COCHLEA OF A COCHLEAR IMPLANT PATIENT 审中-公开
公开(公告)号：WO2019045680A1
公开(公告)日：2019-03-07
申请号：PCT/US2017/048973
申请日：2017-08-28
申请人： ADVANCED BIONICS AG , KOKA, Kanthaiah , LITVAK, Leonid M.
发明人： KOKA, Kanthaiah , LITVAK, Leonid M.
IPC分类号： A61N1/05 , A61N1/36
摘要： An exemplary scalar translocation detection system detects a first evoked response occurring in response to acoustic stimulation applied to a cochlear implant patient. The system detects the first evoked response by way of an electrode configuration disposed on an electrode lead while the electrode configuration is positioned at a first location along an insertion path of the electrode lead into a cochlea of the patient. The system further detects, by way of the electrode configuration while it is positioned at a second location along the insertion path, a second evoked response occurring in response to additional acoustic stimulation applied to the patient. The system further determines an amplitude change and/or a phase change between the first and second evoked responses, and then determines whether a scalar translocation of the electrode lead from one scala of the cochlea to another has occurred based on the amplitude change and/or the phase change.

6. 发明申请

WO2018038821A1 SYSTEMS AND METHODS FOR FACILITATING INTERAURAL LEVEL DIFFERENCE PERCEPTION BY PRESERVING THE INTERAURAL LEVEL DIFFERENCE 审中-公开
标题翻译：用于通过保持国际水平差异来促进国际水平差异感知的系统和方法
公开(公告)号：WO2018038821A1
公开(公告)日：2018-03-01
申请号：PCT/US2017/042274
申请日：2017-07-14
申请人： ADVANCED BIONICS AG , CHEN, Chen , SWAN, Dean , LITVAK, Leonid M.
发明人： CHEN, Chen , SWAN, Dean , LITVAK, Leonid M.
IPC分类号： H04R25/00
摘要： A binaural hearing system (system) enhances and/or preserves interaural level differences between first and second signals. The system includes first and second audio detectors associated with first and second ears of a user, respectively. The audio detectors detect an audio signal presented to the user and generate the first and second signals to represent the audio signal as detected at the first and second ears, respectively. The system also includes a first sound processor that receives the first signal from the first audio detector and the second signal from a second sound processor via a communication link. The first sound processor compares the first and second signals to generate a gain processing parameter, and performs a gain processing operation on a signal based on the gain processing parameter prior to presenting a gain-processed output signal representative of the first signal to the user at the first ear of the user.
摘要翻译：双耳听力系统（系统）增强和/或保持第一和第二信号之间的耳间水平差异。该系统包括分别与用户的第一和第二耳朵相关联的第一和第二音频检测器。音频检测器检测呈现给用户的音频信号并且生成第一和第二信号以分别表示在第一和第二耳朵处检测到的音频信号。该系统还包括第一声音处理器，其经由通信链路接收来自第一音频检测器的第一信号和来自第二声音处理器的第二信号。第一声音处理器比较第一和第二信号以产生增益处理参数，并且在将表示第一信号的经增益处理的输出信号呈现给用户之前，基于增益处理参数对信号执行增益处理操作用户的第一只耳朵。

7. 发明申请

WO2017011196A1 SYSTEMS AND METHODS FOR FACILITATING INTERAURAL TIME DIFFERENCE PERCEPTION BY A BINAURAL COCHLEAR IMPLANT PATIENT 审中-公开
标题翻译：用于促进双侧植入物患者的间歇时间差异的系统和方法
公开(公告)号：WO2017011196A1
公开(公告)日：2017-01-19
申请号：PCT/US2016/040332
申请日：2016-06-30
申请人： ADVANCED BIONICS AG , CHEN, Chen , LITVAK, Leonid M.
发明人： CHEN, Chen , LITVAK, Leonid M.
IPC分类号： A61N1/36 , H04R25/00
CPC分类号： A61N1/36038 , A61N1/36036 , H04R25/407 , H04R25/552 , H04R25/554 , H04R2225/43 , H04R2225/67
摘要： A binaural cochlear implant system (system) includes first and second microphones associated with first and second ears of a patient, respectively. The microphones detect an audio signal presented to the patient and output first and second signals representative of the audio signal as detected at the first and second ears, respectively. The system also includes a first sound processor that receives the first signal from the first microphone and the second signal from a second sound processor by way of a communication link with the second sound processors. The first sound processor generates first and second fine structure signals representative of fine structure information of the first and second signals, respectively, and generates a timing pulse signal based on the first and second fine structure signals. The first sound processor uses the timing pulse signal to represent to the patient an interaural time difference between the first and second signals.
摘要翻译：双耳耳蜗植入系统（系统）分别包括与患者的第一耳和第二耳相关联的第一和第二麦克风。麦克风检测呈现给患者的音频信号，并分别输出表示在第一耳朵和第二耳朵处检测到的音频信号的第一和第二信号。该系统还包括第一声音处理器，其通过与第二声音处理器的通信链路接收来自第一麦克风的第一信号和来自第二声音处理器的第二信号。第一声音处理器分别产生表示第一和第二信号的精细结构信息的第一和第二精细结构信号，并且基于第一和第二精细结构信号产生定时脉冲信号。第一声音处理器使用定时脉冲信号向患者表示第一和第二信号之间的耳间时间差。

8. 发明申请

WO2013165395A1 ELECTROMYOGRAPHY RESPONSE DETECTION SYSTEMS AND METHODS 审中-公开
标题翻译：电磁响应检测系统及方法
公开(公告)号：WO2013165395A1
公开(公告)日：2013-11-07
申请号：PCT/US2012/035979
申请日：2012-05-01
申请人： ADVANCED BIONICS AG , LITVAK, Leonid M. , JOHNSON, William L.
发明人： LITVAK, Leonid M. , JOHNSON, William L.
IPC分类号： A61B5/0488
CPC分类号： A61B5/04012 , A61B5/0488 , A61B5/121 , A61B5/6817 , A61B5/7264 , A61N1/36036
摘要： An exemplary EMG response detection system may be configured to 1) direct an implantable stimulator to sequentially present a plurality of substantially identical stimulation events to a patient, 2) record a plurality of EMG signals generated by a muscle in the patient and each corresponding to a presentation of a particular stimulation event included in the plurality of substantially identical stimulation events, 3) determine an asynchronous component of each of the recorded EMG signals, and 4) utilize the asynchronous components of the recorded EMG signals to determine whether an EMG response is evoked by the stimulation events.
摘要翻译：示例性EMG响应检测系统可以被配置为：1）引导可植入刺激器以向患者顺序呈现多个基本上相同的刺激事件，2）记录由患者中的肌肉产生的多个EMG信号，并且每个对应于呈现包括在多个基本相同的刺激事件中的特定刺激事件，3）确定每个记录的EMG信号的异步分量，以及4）利用记录的EMG信号的异步组件来确定是否诱发EMG响应受到刺激事件的影响。

9. 发明申请

WO2012177424A1 METHODS AND SYSTEMS FOR LOGGING DATA ASSOCIATED WITH AN OPERATION OF A SOUND PROCESSOR BY AN AUDITORY PROSTHESIS 审中-公开
标题翻译：通过审计报告与声音处理器的操作相关联的记录数据的方法和系统
公开(公告)号：WO2012177424A1
公开(公告)日：2012-12-27
申请号：PCT/US2012/041645
申请日：2012-06-08
申请人： ADVANCED BIONICS AG , LITVAK, Leonid M. , MISHRA, Lakshmi N.
发明人： LITVAK, Leonid M. , MISHRA, Lakshmi N.
IPC分类号： A61N1/36
CPC分类号： H04R25/30 , A61N1/36036 , A61N1/37252 , H04R25/305 , H04R25/70 , H04R2225/39 , H04R2225/67
摘要： An exemplary method includes 1) detecting, by an auditory prosthesis configured to be implanted in a patient, a communicative coupling of a sound processor to the auditory prosthesis, the sound processor configured to be located external to the patient, and 2) logging, by the auditory prosthesis, data associated with an operation of the sound processor while the sound processor is communicatively coupled to the auditory prosthesis. Corresponding auditory prostheses and systems are also disclosed.
摘要翻译：示例性方法包括：1）通过构造成植入患者的听觉假体检测声音处理器与听觉假体的通信耦合，所述声音处理器被配置为位于患者外部，以及2）通过听觉假体，与声音处理器的操作相关联的数据，同时声音处理器通信地耦合到听觉假体。还公开了相应的听觉假体和系统。

10. 发明申请

WO2018156820A1 APPARATUSES AND METHODS FOR SETTING COCHLEAR IMPLANT SYSTEM STIMULATION PARAMETERS BASED ON ELECTRODE IMPEDANCE MEASUREMENTS 审中-公开
公开(公告)号：WO2018156820A1
公开(公告)日：2018-08-30
申请号：PCT/US2018/019299
申请日：2018-02-22
申请人： ADVANCED BIONICS AG , CALIXTO, Roger , KOKA, Kanthaiah , SPAHR, Anthony J. , BUSH, Mary Elizabeth , DOWNING, Mark B. , LITVAK, Leonid M. , STEIN, Amy
发明人： CALIXTO, Roger , KOKA, Kanthaiah , SPAHR, Anthony J. , BUSH, Mary Elizabeth , DOWNING, Mark B. , LITVAK, Leonid M. , STEIN, Amy
IPC分类号： A61N1/36
摘要： An apparatus associated with a cochlear implant system used by a patient directs a cochlear implant included within the cochlear implant system and implanted within the patient to generate electrical stimulation current at a predetermined current level. The apparatus further directs the cochlear implant to apply the electrical stimulation current to the patient by way of an electrode coupled with the cochlear implant, and to measure a voltage level associated with the electrode while the electrical stimulation current is applied to the patient by way of the electrode. Based on the predetermined current level and the measured voltage level, the apparatus determines an impedance of the electrode. Based on the determined electrode impedance and in accordance with a predetermined stimulation parameter adjustment constraint, the apparatus automatically adjusts a stimulation parameter associated with the cochlear implant system. Additional apparatuses and corresponding methods are also disclosed.

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