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1. 发明申请

WO2007136647A3 STENT DELIVERY SYSTEM HAVING A STENT STOPPER 审中-公开
公开(公告)号：WO2007136647A3
公开(公告)日：2007-11-29
申请号：PCT/US2007/011721
申请日：2007-05-15
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , ZUCKER, Arik , YRIBARREN, Travis, R. , RIETH, Thomas , COFFEY, Lorcan
发明人： VON OEPEN, Randolf , ZUCKER, Arik , YRIBARREN, Travis, R. , RIETH, Thomas , COFFEY, Lorcan
IPC分类号： A61F2/84
摘要： Disclosed are stent delivery apparatus (200) and methods for moving a balloon (204) catheter carrying a stent (206) through a body vessel without the stent slipping from the balloon are provided. In general, the stent delivery system includes a stent stopper (208, 408, 600) that impedes the stent from slipping from the balloon. The stent stopper is sized to serve as a barrier to the stent as it is carried on the balloon. In a specific embodiment, the stent stopper is formed from a material that encircles the proximal end of the balloon and abuts the proximal end of the stent. The stent stopper material expands with expansion of the balloon and collapses with deflation of the balloon. In some embodiments, the stent stopper material has a thickness (302, 502) that is about equal to or greater than the thickness of the stent so as to form a barrier against the stent and impede the stent from slipping off the proximal end of the balloon.

2. 发明申请

WO2006138741A1 METHOD OF REDUCING RIGIDITY OF ANGIOPLASTY BALLOON SECTIONS 审中-公开
标题翻译：降低血管平滑肌血管紧张性的方法
公开(公告)号：WO2006138741A1
公开(公告)日：2006-12-28
申请号：PCT/US2006/024198
申请日：2006-06-19
申请人： ABBOTT LABORATORIES , YRIBARREN, Travis , VON OEPEN, Randolf , RIETH, Thomas , COFFEY, Lorcan , ZUCKER, Arik , WARNACK, Boris , HARTWIG, Judith , PSCHIBL, Silke
发明人： YRIBARREN, Travis , VON OEPEN, Randolf , RIETH, Thomas , COFFEY, Lorcan , ZUCKER, Arik , WARNACK, Boris , HARTWIG, Judith , PSCHIBL, Silke
IPC分类号： A61M25/10 , A61M25/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2203/42 , B23K2203/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon (10) is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections . A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections (13, 12) of the balloon are defined and if desired, indentations in the cone sections (15, 14) are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的过程制造扩张球囊（10）。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。限定球囊的套筒部分（13,12）中的腔，并且如果需要，限定锥体部分（15,14）中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更柔软的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。

3. 发明申请

WO2006119503A1 GUIDEWIRE APPARATUS WITH AN EXPANDABLE PORTION 审中-公开
标题翻译： GUIDEWIRE设备与可扩展部分
公开(公告)号：WO2006119503A1
公开(公告)日：2006-11-09
申请号：PCT/US2006/017602
申请日：2006-05-04
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , YRIBARREN, Travis , RIETH, Thomas , COFFEY, Lorcan , ZUCKER, Arik
发明人： VON OEPEN, Randolf , YRIBARREN, Travis , RIETH, Thomas , COFFEY, Lorcan , ZUCKER, Arik
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61M2025/09125 , A61M2025/09175 , A61M2025/09183
摘要： A guidewire apparatus for a medical device that includes an expandable guidewire section that can be locked in an expanded state. In one use, the expandable section can be temporarily locked to a working element of a medical device to facilitate the transmission of torque from the guidewire to the medical device. Hence, this configuration may be utilized to aid in orientation of the working element with a vessel side branch by providing the user with the ability to apply a rotational force to the distal end of the stent delivery system. Another use includes docking the expandable section near an opening into a guidewire lumen at the catheter tip. This configuration is particularly useful in forming a smooth transition between the guidewire and the catheter tip to reduce the phenomenon of fish-mouthing.
摘要翻译：一种用于医疗装置的导丝装置，其包括能够被锁定在展开状态的可扩张导丝部分。在一种用途中，可扩张部分可以临时锁定到医疗装置的工作元件，以便于将扭矩从导丝传递到医疗装置。因此，这种构造可以用于通过向使用者提供向支架输送系统的远端施加旋转力的能力来帮助工作元件与血管侧分支的取向。另一种用途包括将开口附近的可扩张部分对接在导管尖端处的导丝管腔中。这种构造在形成导丝和导管尖端之间的平滑过渡以减少鱼嘴的现象特别有用。

4. 发明申请

WO2006127920A1 BIFURCATION STENT DELIVERY CATHETER ASSEMBLY AND METHOD 审中-公开
标题翻译：分叉杆输送管组件和方法
公开(公告)号：WO2006127920A1
公开(公告)日：2006-11-30
申请号：PCT/US2006/020283
申请日：2006-05-24
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , RIETH, Thomas , COFFEY, Lorcan , ZUCKER, Arik , YRIBARREN, Travis
发明人： VON OEPEN, Randolf , RIETH, Thomas , COFFEY, Lorcan , ZUCKER, Arik , YRIBARREN, Travis
IPC分类号： A61F2/84
CPC分类号： A61F2/958 , A61F2/856 , A61F2/954 , A61M2025/09125 , A61M2025/1015
摘要： A stent delivery system (40), is disclosed for delivering and deploying a radially expandable stent (41) at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft (43) sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion (45) supporting a dilator device (47) adapted for radial expansion about a longitudinal axis of the deployment assembly (45) from a non-expanded condition to a radially expanded condtion. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly (48) rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel .
摘要翻译：公开了一种支架输送系统（40），用于在体内血管的战略取向和位置处递送和展开径向可扩张的支架（41）。输送系统包括适于插入体内容器的细长柔性管状轴（43）。支架展开组件包括支撑扩张器装置（47）的远侧过渡部分（45），该扩张器装置适于围绕展开组件（45）的纵向轴线从非扩张状态到径向扩张的条件的径向膨胀。扩张器装置构造成在非扩张状态下以相对于展开组件的预定取向支撑其上的支架。旋转离合器组件（48）将过渡部分可旋转地安装到管状轴的远端部分，使得展开组件围绕离合器组件的纵向轴线与管状轴线基本上扭转隔离。这使得支架部署能够基本上独立于管状轴线旋转，用于在穿过身体血管的前进过程中扩张器装置的战略取向。

5. 发明申请

WO2007002423A2 BALLOON CATHETER 审中-公开
标题翻译：气球导管
公开(公告)号：WO2007002423A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/024512
申请日：2006-06-23
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , COFFEY, Lorcan , RIETH, Thomas , YRIBARREN, Travis , ZUCKER, Arik
发明人： VON OEPEN, Randolf , COFFEY, Lorcan , RIETH, Thomas , YRIBARREN, Travis , ZUCKER, Arik
CPC分类号： A61M25/10 , A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1045 , A61M2025/1056 , A61M2025/107 , A61M2029/025
摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.
摘要翻译：描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔径向隔开，使得在可膨胀构件之间形成至少一个间隙。通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。

6. 发明申请

WO2008021570A2 BIFURCATION STENT DELIVERY CATHETER AND METHOD 审中-公开
标题翻译：分叉杆输送管和方法
公开(公告)号：WO2008021570A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/018441
申请日：2007-08-20
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , COFFEY, Lorcan , RIETH, Thomas , NEWHAUSER, Richard , YRIBARREN, Travis , WILSON, Bruce
发明人： VON OEPEN, Randolf , COFFEY, Lorcan , RIETH, Thomas , NEWHAUSER, Richard , YRIBARREN, Travis , WILSON, Bruce
IPC分类号： A61F2/84 , A61M25/10
CPC分类号： A61F2/954 , A61F2/856 , A61F2002/30329 , A61F2220/0025
摘要： A bifurcation stent delivery catheter includes a first branch balloon, a second branch balloon adjacent the first branch. A centering balloon is optionally disposed distal of the second branch balloon. The balloons are coupled by a coupling device to a main shaft of a catheter. The coupling device allows axial forces to be transmitted from the main shaft to the balloons while allowing the balloons to rotate axially relative to the main shaft with ease. The coupling device functions as an axial rotational joint. The coupling device can have a flexible tubular member that connects the balloons to the main shaft, the tubular member having a torsional flexibility greater than that of the main shaft. The coupling device can have a tubular wall having a cut extending circumferentially around the tubular wall and protective boot covering the cut. The coupling device can have a wound member that allows the axial rotation.
摘要翻译：分叉支架输送导管包括第一分支气囊，邻近第一分支的第二分支球囊。定心球可选地设置在第二分支气囊的远侧。气囊通过联接装置耦合到导管的主轴。联接装置允许轴向力从主轴传递到气球，同时允许气囊相对于主轴容易地轴向旋转。联接装置用作轴向旋转接头。联接装置可以具有将气囊连接到主轴的柔性管状构件，该管状构件具有大于主轴的扭转灵活性。联接装置可以具有管状壁，其具有围绕管状壁周向延伸的切口和覆盖切口的保护靴。联接装置可以具有允许轴向旋转的卷绕构件。

7. 发明申请

WO2007124161A1 GUIDEWIRE PLACEMENT DEVICE 审中-公开
标题翻译： GUIDEWIRE放置设备
公开(公告)号：WO2007124161A1
公开(公告)日：2007-11-01
申请号：PCT/US2007/009888
申请日：2007-04-23
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , COFFEY, Lorcan , NEWHAUSER, Richard , RIETH, Thomas , YRIBARREN, Travis
发明人： VON OEPEN, Randolf , COFFEY, Lorcan , NEWHAUSER, Richard , RIETH, Thomas , YRIBARREN, Travis
IPC分类号： A61M25/09 , A61M25/06 , A61M25/01
CPC分类号： A61M25/0029 , A61M25/0071 , A61M25/01 , A61M25/0108 , A61M2025/0037 , A61M2025/0063 , A61M2025/018
摘要： This invention describes a guidewire placement device for facilitating the delivery of multiple guidewires to the branches of a tubular system. The invention also includes a method for placing guidewires in the branches of a tubular system using a device in accordance with the present invention, while mitigating guidewire entanglement. The present invention may be utilized during percutaneous treatment of vascular and non-vascular disease, and in particular to complement the use of balloon angioplasty and the deployment of balloon-expanded or self-expanding stents into a bifurcated vessel system.
摘要翻译：本发明描述了一种用于便于将多条导丝输送到管状系统的分支的引导线放置装置。本发明还包括一种使用根据本发明的装置将导线布置在管状系统的分支中的方法，同时减轻导丝缠结。本发明可以用于血管和非血管疾病的经皮处理，特别是补充气囊血管成形术的使用和将球囊扩张或自扩张支架部署到分叉血管系统中。

8. 发明申请

WO2007103553A1 BIFURCATION STENT DELIVERY CATHETER AND METHOD 审中-公开
标题翻译：分叉杆输送管和方法
公开(公告)号：WO2007103553A1
公开(公告)日：2007-09-13
申请号：PCT/US2007/006033
申请日：2007-03-08
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , RIETH, Thomas , COFFEY, Lorcan , NEWHAUSER, Richard , YRIBARREN, Travis
发明人： VON OEPEN, Randolf , RIETH, Thomas , COFFEY, Lorcan , NEWHAUSER, Richard , YRIBARREN, Travis
IPC分类号： A61F2/06
CPC分类号： A61F2/95
摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel, first and second inflatable members disposed adjacent the distal end of the elongated shaft and an endoprosthesis disposed about the first and second inflatable members. The delivery system further includes a tip assembly which during advancement of the delivery system is configured as a single tip assembly, wherein prior to deployment of the expandable endoprosthesis, the tip assembly is split into a first tip and a second tip, wherein one of the tips remains in a main branch and the second tip is advanced into a side branch lumen to align the endoprosthesis prior to deployment.
摘要翻译：公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。递送系统包括细长的柔性管状轴，其尺寸适于插入身体容器中，邻近细长轴的远端设置的第一和第二可膨胀构件以及围绕第一和第二可膨胀构件设置的内假体。输送系统还包括尖端组件，其在输送系统的进给期间被配置为单个尖端组件，其中在展开可膨胀内置假体之前，将尖端组件分成第一尖端和第二尖端，其中尖端保留在主分支中，并且第二尖端进入侧分支内腔以在部署之前对准内假体。

9. 发明申请

WO2007124495A2 STIFFENING SUPPORT CATHETER AND METHODS FOR USING THE SAME 审中-公开
标题翻译：加强支撑导管及使用该导管的方法
公开(公告)号：WO2007124495A2
公开(公告)日：2007-11-01
申请号：PCT/US2007/067237
申请日：2007-04-23
申请人： ABBOTT LABORATORIES , VON OEPEN, Randolf , COFFEY, Lorcan , REITH, Thomas , NEWHAUSER, Richard , YRIBARREN, Travis , GIANOTTI, Marc , UIHLEIN, Bernhard , CLARK, Ian, J.
发明人： VON OEPEN, Randolf , COFFEY, Lorcan , REITH, Thomas , NEWHAUSER, Richard , YRIBARREN, Travis , GIANOTTI, Marc , UIHLEIN, Bernhard , CLARK, Ian, J.
IPC分类号： A61M25/00
CPC分类号： A61M25/01 , A61B2017/003 , A61B2017/00336 , A61M25/0045 , A61M25/0053 , A61M25/008 , A61M2025/0183
摘要： A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.
摘要翻译：提供了一种支撑导管，其可以用导丝刺穿心脏隔膜而不会屈曲，并且可以在困难的情况下从主动脉接近难以到达的动脉，例如颈动脉或肾动脉。支撑导管包括具有近端，远端和内壁表面的导管主体，所述内壁表面限定从近端朝向远端延伸的第一腔。第二内腔设置在内壁表面和导管主体的外表面之间。多个加强构件设置在第二腔周围，多个加强构件可接合以选择性地加强导管主体。在另一种配置中，导管还包括布置在第一腔和第二腔之间的第二多个加强构件。

10. 发明申请

WO2004014256A1 APPARATUS FOR DELIVERING AND DEPLOYMENT OF AN EXPANDABLE STENT WITHIN A BLOOD VESSEL 审中-公开
标题翻译：用于在血管中输送和分配可膨胀的血管的装置
公开(公告)号：WO2004014256A1
公开(公告)日：2004-02-19
申请号：PCT/EP2003/008795
申请日：2003-08-07
申请人： ABBOTT LABORATORIES VASCULAR ENTERPRISES, LTD. , VON OEPEN, Randolf , TRÖSKEN, Volker , MARX, Volker , STOPPER, Armin , BALFE, Louise , COFFEY, Lorcan
发明人： VON OEPEN, Randolf , TRÖSKEN, Volker , MARX, Volker , STOPPER, Armin , BALFE, Louise , COFFEY, Lorcan
IPC分类号： A61F2/06
CPC分类号： A61F2/958
摘要： An improved apparatus for delivering and deployment of an expandable stent with a protection sheath within a blood vessel is provided. The system comprises a fluid pressure device which is coupled with a retraction device for the protection sheath such that after retraction of the protection sheath the stent is automatically deployed by the fluid pressure device. The advantage of the invention is an easy and simple operation of the apparatus.
摘要翻译：提供了一种用于在血管内输送和展开具有保护护套的可扩张支架的改进装置。该系统包括流体压力装置，该流体压力装置与用于保护护套的收回装置相耦合，使得在退回保护套之后，支架由流体压力装置自动展开。本发明的优点是装置的简单和简单的操作。

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