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1. 发明公开

KR1020020078513A 구강위생용품 판매방법 无效
标题翻译：出售口腔卫生用品的方法
公开(公告)号：KR1020020078513A
公开(公告)日：2002-10-19
申请号：KR1020010017644
申请日：2001-04-03
申请人： 황현식 , 김정문 , 이종석 , 박영철
发明人： 황현식 , 김정문 , 이종석 , 박영철
IPC分类号： G06Q30/06 , G06Q50/22
摘要： PURPOSE: A method for selling supplies for an oral hygiene is provided to sell supplies for an oral hygiene to a person or a hospital using an electronic commerce and to sell package based on a prescription of a doctor with respect to various kinds of oral disease symptoms. CONSTITUTION: In the case that a patient receives a diagnosis from a doctor directly or in a hospital homepage through a hospital menu(S50), the doctor refers to a diagnosis record of the patient(S54) stored in an ISP(S52) and performs a consultation with the patient(S56). If supplies for an oral hygiene necessary for a treatment are recorded in an electronic chart(S58), the patient purchases the recorded supplies through the ISP. Data with respect to the diagnosis and a prescription are stored in a database of a personal area(S62). In a question list(S66) with respect to a symptom output using a self-diagnosis menu(S64), the patient selects questions with respect to a corresponding symptom(S68), and a diagnosis and prescription with respect to the disease are received(S70).
摘要翻译：目的：提供一种销售口腔卫生用品的方法，使用电子商务向个人或医院出售口腔卫生用品，并根据各种口腔疾病症状的医生处方出售包装。构成：在患者通过医院菜单直接或在医院主页诊断的情况下（S50），医生参照存储在ISP（S52）中的病人的诊断记录（S54），并执行与患者协商（S56）。如果在电子图表中记录了用于治疗所需的口腔卫生用品（S58），则患者通过ISP购买记录的用品。关于诊断和处方的数据存储在个人区域的数据库中（S62）。在关于使用自诊断菜单的症状输出的问题列表（S66）（S64）中，患者选择关于相应症状的问题（S68），并且接收关于疾病的诊断和处方（ S70）。

2. 发明公开

KR1020020051454A 두부 방사선 촬영을 위한 기준계 失效
标题翻译：头部放射线的参考框架
公开(公告)号：KR1020020051454A
公开(公告)日：2002-06-29
申请号：KR1020000080500
申请日：2000-12-22
申请人： 황현식 , 김정문 , 이종석
发明人： 황현식 , 김정문 , 이종석
IPC分类号： A61B6/14
摘要： PURPOSE: A reference frame for head radiography is provided to perform an accurate diagnosis by replaying a natural head posture of a patient in a time difference. CONSTITUTION: A leg unit(2) has a horizontal frame(5). A frame(3) is combined with the leg unit(2). A clear panel member(4) which is mounted on the frame(3) is coated with a radiation impermeable material. The clear panel member(4) moves in a groove(9) which is formed on a horizontal part(7) and a vertical part(8) of the frame(3). The clear panel member(4) displays a horizontal and vertical position of a pupil as a reference in which symmetry in a face of a patient is judged through a radiography.
摘要翻译：目的：提供用于头部放射线摄影的参考框架，以通过以时间差重放患者的自然头部姿势来执行准确的诊断。构成：腿部单元（2）具有水平框架（5）。框架（3）与腿单元（2）组合。安装在框架（3）上的透明面板构件（4）涂覆有辐射不可渗透材料。透明板构件（4）在形成在框架（3）的水平部分（7）和垂直部分（8）上的凹槽（9）中移动。透明面板构件（4）显示瞳孔的水平和垂直位置作为参考，其中通过放射照相术来判断患者面部的对称性。

3. 发明授权

KR100401047B1 두부 방사선 촬영을 위한 기준계 失效
标题翻译： 두부방사선촬영을위한기준계
公开(公告)号：KR100401047B1
公开(公告)日：2003-10-10
申请号：KR1020000080500
申请日：2000-12-22
申请人： 황현식 , 김정문 , 이종석
发明人： 황현식 , 김정문 , 이종석
IPC分类号： A61B6/14
摘要： PURPOSE: A reference frame for head radiography is provided to perform an accurate diagnosis by replaying a natural head posture of a patient in a time difference. CONSTITUTION: A leg unit(2) has a horizontal frame(5). A frame(3) is combined with the leg unit(2). A clear panel member(4) which is mounted on the frame(3) is coated with a radiation impermeable material. The clear panel member(4) moves in a groove(9) which is formed on a horizontal part(7) and a vertical part(8) of the frame(3). The clear panel member(4) displays a horizontal and vertical position of a pupil as a reference in which symmetry in a face of a patient is judged through a radiography.
摘要翻译：目的：提供头部放射线摄影的参考框架，通过以时间差异重放患者的自然头部姿势来执行准确的诊断。构成：腿部单元（2）具有水平框架（5）。框架（3）与腿部单元（2）组合。安装在框架（3）上的透明面板构件（4）涂覆有不透辐射材料。透明面板部件（4）在框架（3）的水平部分（7）和垂直部分（8）上形成的凹槽（9）中移动。透明面板构件（4）显示作为参考的瞳孔的水平和垂直位置，其中通过放射摄影来判断患者脸部的对称。

4. 实用新型

KR200365283Y1 임플랜트 失效
公开(公告)号：KR200365283Y1
公开(公告)日：2004-10-20
申请号：KR2020040022302
申请日：2004-08-04
申请人： 김정문 , 김종우 , 이종석 , 박영철
发明人： 김정문 , 김종우 , 박영철 , 이종석
IPC分类号： A61C8/00
CPC分类号： A61C8/0096 , A61C7/22 , A61C7/30
摘要： 본 고안은 치열교정시술시 치조골에 식립되는 임플랜트에 관한 것으로, 상부에 헤드(31)가 형성되고 그 하부는 탄성부재를 고정하는 고정부(32), 공구를 결합하는 공구결합부(33), 치조골에 식립되는 식립부(34) 및 소정의 길이를 갖는 스크루(35)가 순차적으로 형성된 임플랜트에 있어서, 상기 스크루(35)는 외경 크기가 식립부(34)로부터 멀어질수록 작아지는 원추형상을 가지며, 상기 스크루(35)에 나선 모양으로 돌출 형성된 날(36)은 상기 식립부(34)에 인접한 부위의 끝단(37)이 소정 폭을 갖는 면(38)으로 형성되고 다른 부위의 끝단(37)이 뾰족한 형상을 갖도록 형성되며, 상기 식립부(34)의 하단 부위에서 시작하여 소정 길이에 걸쳐 날(36)을 절개하는 형상으로 홈(39)이 형성됨을 특징으로 하며, 이러한 구성에 의하면 드릴링 과정이 불필요하여 식립 시술이 간� �하게 이루어지며 치열 교정시 임플랜트에 가해지는 힘이 분산되고 임플랜트를 치조골에 식립할 때 치조골에 형성되는 응력을 감소시킬 수 있는 우수한 효과를 갖는다.

5. 实用新型

KR200289252Y1 임플랜트 失效
标题翻译：注入
公开(公告)号：KR200289252Y1
公开(公告)日：2002-09-16
申请号：KR2020020019455
申请日：2002-06-27
申请人： 김정문 , 김종우 , 이종석 , 박영철
发明人： 김정문 , 김종우 , 박영철 , 이종석
IPC分类号： A61C8/00
摘要： 본 고안은 치열교정 시술을 할 때에 치조골에 식립하여 사용되는 임플랜트의 스크루부 구조를 변형하여 된 임플랜트에 관한 것으로서, 상부에 헤드가 형성되어 있고 그 하부에는 탄성부재를 고정하는 고정부, 공구를 결합하는 공구결합부 및 치골조에 식립되는 식립부와 소정의 길이를 갖는 스크루가 순차적으로 형성된 임플랜트에 있어서, 상기 스크루는 상광하협의 원추형으로 이루어지고 그 원추형으로 이루어진 스크루의 날 중 상부 1개층 또는 2개층 이상의 스크루 날 끝단은 소정의 폭을 갖는 면이 형성되고 그 하부의 스크루 날 끝단은 예리한 각을 형성시킴으로서, 별도의 드릴링 과정 없이 식립할 수 있음과 동시에 탄성부재의 장력에 따라 발생할 수 있는 응력을 적절하게 분산시킴으로써 임플랜트와 치조골의 계면을 건강하게 유지할 수 있는 효과가 있다.

6. 发明公开

KR1020020065873A 임플랜트 失效
标题翻译：注入
公开(公告)号：KR1020020065873A
公开(公告)日：2002-08-14
申请号：KR1020020036393
申请日：2002-06-27
申请人： 김정문 , 김종우 , 이종석 , 박영철
发明人： 김정문 , 김종우 , 박영철 , 이종석
IPC分类号： A61C8/00
CPC分类号： A61C8/0022 , A61C8/0096
摘要： PURPOSE: An implant is provided to be implanted without requiring a separate drilling process, and to maintain a stable condition between the implant and the interface of alveolus by appropriately dispersing a stress generated according to a tension force of an elastic member. CONSTITUTION: In the implant successively formed with a head(31), a fixing part(32) for an elastic member, a tool coupling portion(33), an implantation part(34) to be implanted in the alveolus, and a screw(35) having a certain length, the screw has a conical shape that its diameter becomes small from the upper part to the lower part, and the distal edge(37) of one or two upper thread(s) among conical screw threads(36) forms a flat plane(38) having a certain width, and the opposite lower end of the screw forms an acute angle.
摘要翻译：目的：提供植入物，而不需要单独的钻孔过程，并且通过适当地分散根据弹性构件的张力产生的应力来保持植入物和牙槽的界面之间的稳定状态。构成：在连续形成有头部（31）的植入物中，用于弹性构件的固定部分（32），工具联接部分（33），植入在肺泡中的植入部分（34）和螺钉 35）具有一定长度，螺杆具有从上部到下部的直径变小的锥形形状，锥形螺纹（36）中的一个或两个面线的远端边缘（37）形成具有一定宽度的平面（38），并且螺钉的相对的下端形成锐角。

7. 发明授权

KR100430770B1 임플랜트 失效
公开(公告)号：KR100430770B1
公开(公告)日：2004-05-17
申请号：KR1020020036393
申请日：2002-06-27
申请人： 김정문 , 김종우 , 이종석 , 박영철
发明人： 김정문 , 김종우 , 박영철 , 이종석
IPC分类号： A61C8/00
CPC分类号： A61C8/0022 , A61C8/0096
摘要： Disclosed is an orthodontic implant (30) having a head part (31) formed at an upper end thereof, a connection part (32) for connection of an elastic member, a tool engagement part (33) for engagement of a tool, a uniform diameter part (34), and a screw part (35) having a predetermined length to be driven into an alveolar bone (10), which are sequentially formed in a downward direction. The screw part (35) of the present invention has a sectional shape of an inverted cone which is widened at an upper end thereof and pointed at a lowered end thereof, and a pre-selected upper portion of a thread (36) of the screw pad, which portion corresponds to one or more leads of the thread, is formed to have a flattened crest (38) of a predetermined width, and the remaining portion of the threads of the screw part (35) are formed to have sharp-edged crest (37).
摘要翻译：本发明公开了一种正牙种植体（30），其具有形成在其上端的头部（31），用于连接弹性构件的连接部分（32），用于接合工具的工具接合部分（33）以及具有预定长度的螺纹部分（35），所述螺纹部分（35）被驱入牙槽骨（10）中，所述螺纹部分（35）沿着向下的方向依次形成。本发明的螺纹部分（35）具有倒锥形的截面形状，其上端加宽并指向其下端，螺纹（36）的预选上部与螺纹的一个或多个导线相对应的衬垫形成为具有预定宽度的扁平顶部（38），并且螺钉部分（35）的螺纹的其余部分形成为具有锐边波峰（37）。

8. 实用新型

KR200315723Y1 치아교정 시술용 보조구 失效
标题翻译：正畸治疗的辅助工具
公开(公告)号：KR200315723Y1
公开(公告)日：2003-06-09
申请号：KR2020020038706
申请日：2002-12-27
申请人： 김정문 , 김종우 , 이종석 , 박영철
发明人： 김정문 , 김종우 , 박영철 , 이종석
IPC分类号： A61C7/02
CPC分类号： A61C7/12 , A61C7/22 , A61C7/30 , A61C8/0096
摘要： 본 고안은 치아교정시술을 위하여 해당 치아에 부착된 브래킷에 견인력 또는 지지력을 부여해주는 탄성부재의 일측단을 걸어 고정하는 치아교정 시술용 보조구에 관한 것으로, 이는 소정의 길이와 탄성력을 갖는 금속 심이 호형으로 밴딩되고 그 호형으로 밴딩된 금속 심의 중앙부에는 교정용 임플랜트와 연결되는 2개의 고정부가 형성되며 상기 고정부를 중심으로 금속 심의 양측에는 탄성부재 체결부를 형성시켜 된 것이다.

9. 发明授权

KR100874947B1 비활성 Ｗｎｔ 저해 폴리펩티드 및 그 제조방법 失效
标题翻译： 비활성Wnt저해폴리펩티드및그제조방법
公开(公告)号：KR100874947B1
公开(公告)日：2008-12-19
申请号：KR1020060119560
申请日：2006-11-30
申请人： 김정문 , 김정국 , 김태한 , 이종석
发明人： 김정문 , 김정국 , 김태한 , 이종석 , 육종인
IPC分类号： C07K19/00
CPC分类号： C07K14/475 , C07K14/4703
摘要： The present invention relates to non-activated Wnt inhibition polypeptides (WIPs) containing: (a) a protein transduction domain (PTD) which enables said WIPs to permeate a cell membrane without the aid of a cell membrane receptor; and (b) a Wnt antagonist domain which is inactive by itself, but is activated in mammalian cells and then secreted out of the cells to function to inhibit Wnt signal transduction. Also, the invention relates to a method for preparing said non-activated WIPs, and a pharmaceutical composition containing said WIPs as active ingredients. Said non-activated WIPs can be produced in large quantities through the culture of bacteria such as E coli., and are biochemically inactive before being administered into the human body, and thus the production cost thereof is only one several tenths of that of previously known active proteins (sFRPs, DKKs, etc.) having uses similar thereto, and the isolation/purification and handling/administration processes thereof are significantly simple and convenient. When said non-activated WIPs are administered in vivo, they will have the effects of inhibiting the invasive growth and metastasis of cancer cells and treating immune diseases, such as rheumatoid arthritis by pharmacological mechanisms different from those of the previously known sFRPs or DKKs.
摘要翻译：本发明涉及未激活的Wnt抑制多肽（WIP），其含有：（a）蛋白质转导结构域（PTD），其使所述WIP能够在不借助细胞膜受体的情况下渗透细胞膜; 和（b）Wnt拮抗剂结构域，其本身无活性，但在哺乳动物细胞中被活化，然后从细胞中分泌出来以起到抑制Wnt信号转导的作用。而且，本发明涉及制备所述未活化的WIP的方法，以及含有所述WIP作为活性成分的药物组合物。所述未活化的WIP可以通过培养细菌如大肠杆菌而大量生产，并且在施用到人体内之前是生物化学非活性的，因此其生产成本仅为先前已知的几十分之一具有类似用途的活性蛋白（sFRP，DKK等）以及其分离/纯化和处理/施用过程非常简单和方便。当所述未激活的WIPs在体内给药时，它们将具有抑制癌细胞的侵袭性生长和转移以及通过不同于先前已知的sFRP或DKKs的药理学机制治疗免疫疾病如类风湿性关节炎的作用。

10. 发明公开

KR1020080044710A 향상된 세포 투과능 및 조직재생 기능을 가지는 비활성폴리펩티드, 및 그 용도 无效
标题翻译：具有组织再生功能和改善细胞渗透性的非活性多聚体及其使用
公开(公告)号：KR1020080044710A
公开(公告)日：2008-05-21
申请号：KR1020060114114
申请日：2006-11-17
申请人： 김정문 , 김정국 , 김태한 , 이종석
发明人： 김정문 , 김정국 , 김태한 , 이종석 , 육종인
IPC分类号： C07K14/475 , C07K14/00
摘要： A non-activated HD(HA2 domain)-PTD(protein transduction domain)-FAD(furin activation domain)-TRD(tissue regeneration domain) polypeptide is provided to show improved cell permeability compared with conventional TRPs(tissue regenerative polypeptides) containing the PTD, FAD and TRD, be mass-produced by culturing a recombinant microorganism and promote formation or regeneration of a tissue when administered into a living organism due to high cell permeability. A non-activated polypeptide is characterized in that an HD for increasing cell permeability is coupled to a TRP including a PTD, a FAD and a TRD. A recombinant vector is characterized in that a nucleotide sequence encoding the FAD, a nucleotide sequence of the PTD, a nucleotide sequence of the HA2 domain, a nucleotide sequence for tagging, and a nucleotide sequence encoding at least 4 histidines for isolation and purification are inserted in front of 5' of DNA encoding the TRD. A method for preparing the non-activated polypeptide comprises the steps of: (a) culturing a bacteria transformed by the recombinant vector to express a [HD-PTD-FAD-TRD] polypeptide; and (b) after centrifuging a culture solution obtained from the step(a), adding a urine solution to a cell pellet to remove two-dimensional and three-dimensional structures of the polypeptide or to modify them into one-dimensional linear structure and then purifying the [HD-PTD-FAD-TRD] polypeptide. A composition for promoting formation or regeneration of a tissue or promoting regeneration comprises the non-activated polypeptide as an effective ingredient.
摘要翻译：提供非活化的HD（HA2结构域）-PTD（蛋白质转导结构域）-FAD（弗林蛋白酶激活结构域）-TRD（组织再生结构域）多肽以显示与含有PTD的常规TRP（组织再生多肽）相比改善的细胞通透性，FAD和TRD通过培养重组微生物而大量生产，并且由于高细胞渗透性而在施用于生物体时促进组织的形成或再生。非活化多肽的特征在于用于增加细胞渗透性的HD与包括PTD，FAD和TRD的TRP偶联。重组载体的特征在于插入编码FAD的核苷酸序列，PTD的核苷酸序列，HA2结构域的核苷酸序列，标记的核苷酸序列和编码用于分离和纯化的至少4种组氨酸的核苷酸序列在编码TRD的DNA的5'前面。制备非活化多肽的方法包括以下步骤：（a）培养由重组载体转化的细菌以表达[HD-PTD-FAD-TRD]多肽; 和（b）离心分离步骤（a）得到的培养液后，向细胞沉淀中加入尿液以除去多肽的二维和三维结构，或将其修饰成一维线性结构，然后纯化[HD-PTD-FAD-TRD]多肽。用于促进组织形成或再生或促进再生的组合物包含非活化多肽作为有效成分。

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