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    • 9. 发明公开
    • 실리마린을 포함하는 자극성 접촉피부염 예방 및 치료용약학적 조성물
    • 包含SILYMARIN的药物组合物用于预防和治疗刺激性接触剂量
    • KR1020070093918A
    • 2007-09-19
    • KR1020070025618
    • 2007-03-15
    • 한국생명공학연구원
    • 김환묵박성규강종순한미화이기호한상배이기훈이창우
    • A61K8/49A61K31/357A61P17/00A61Q19/00
    • A61K8/498A61K8/022A61K8/04A61K31/357Y10S514/857
    • A pharmaceutical composition comprising silymarin is provided to be useful for inhibiting increase of the thickness of ear, increase of the moisture content of the ear, increase of lymph node weight and expression of TNF-alpha, thereby capable of preventing and treating irritant contact dermatitis. A pharmaceutical composition for irritant contact dermatitis comprises silymarin or main ingredients thereof such as silybin, silidianin and silicristin, wherein the silymarin or the main ingredients thereof inhibits the excessive production of TNF-alpha. The cosmetics is in the form of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritive lotion, massage cream, nutritive cream, moisture cream, hand cream, essence, nutritive essence, pack, soap, shampoo, cleansing foam, cleansing lotion, cleansing cream, body lotion, body cleanser, emulsion, press powder, or loose powder.
    • 提供含有水飞蓟素的药物组合物可用于抑制耳朵厚度增加,耳朵水分含量增加,淋巴结重量增加和TNF-α表达,从而能够预防和治疗刺激性接触性皮炎。 用于刺激性接触性皮炎的药物组合物包含水飞蓟素或其主要成分,例如水飞蓟宾,硅藻土和硅藻土,其中水飞蓟马或其主要成分抑制TNF-α的过量产生。 化妆品是以皮肤洗剂,皮肤柔肤剂,皮肤调色剂,收敛剂,乳液,乳液,滋润乳液,营养乳液,按摩霜,营养霜,保湿霜,护手霜,精华液,营养精华,包装,肥皂, 洗发水,清洁泡沫,清洁乳液,清洁霜,身体乳液,身体清洁剂,乳液,压粉或松散粉末。