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    • 1. 发明授权
    • 줄기세포 배양액을 이용한 멜라닌 합성저해 방법
    • 使用成熟干细胞培养的梅毒素合成的抑制
    • KR100848056B1
    • 2008-07-23
    • KR1020070076221
    • 2007-07-30
    • 주프로스테믹스박병순
    • 박병순김원석성종혁안세진
    • A61K8/64A61K8/98A61Q19/02
    • A61Q19/02A61K8/99A61K35/28A61K35/51
    • A cosmetic composition comprising the cultured medium of adult stem cells is provided to inhibit synthesis of melanin and activity of tyrosinase without side effects, so that the composition is useful for whitening the skin. A cosmetic composition for whitening the skin comprises the cultured medium of adult stem cells derived from mammals, especially adipocytes, bone marrow tissue and umbilical cord blood of mammals or proteins separated from the cultured medium, wherein the adult stem cell is isolated from adipocytes by obtaining fat tissue through liposuction, treating the extracellular matrix of fat tissue with collagenase, centrifuging the enzyme-treated product to divide the enzyme-treated product into monocytes, hematocytes and several cell debris.
    • 提供包含成体干细胞的培养基的化妆品组合物,以抑制黑色素的合成和酪氨酸酶的活性而没有副作用,使得该组合物可用于使皮肤美白。 用于使皮肤美白的化妆品组合物包含哺乳动物,特别是脂肪细胞,骨髓组织和来自培养基的蛋白质分离的骨髓组织和脐带血的成体干细胞的培养基,其中通过获得成体干细胞从脂肪细胞分离 通过脂肪抽吸脂肪组织,用胶原酶处理脂肪组织的细胞外基质,离心酶处理产物以将酶处理的产物分成单核细胞,血细胞和几个细胞碎片。