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    • 5. 发明公开
    • 비짜루국화 추출물을 함유하는 피부 상태개선용 조성물
    • 用于改善包含ASTER SUBULATUS MICHX提取物的皮肤条件的组合物
    • KR1020100005557A
    • 2010-01-15
    • KR1020080065646
    • 2008-07-07
    • 재단법인 제주테크노파크
    • 김기옥강민철고려경한종헌김행범이주엽안승현고광효김봉석이남호유병삼
    • A61K8/97A61Q19/00A61Q19/02
    • PURPOSE: A composition containing Aster subulatus extract for improving skin condition is provided to ensure anti-inflammatory effect through anti-oxidation, meganogenesis suppression, and NO generation suppression. CONSTITUTION: A composition for improving skin condition contains Aster subulatus extract or its solvent fraction as an active ingredient. The Aster subulatu extract is obtained by pulverizing dried Aster subulatu, dipping the pulverized Aster subulatu in 70% ethanol, stirring for 2-3 days, filtering, compress-concentrating, and freeze-drying. The solvent fraction is ethanol extract, hexane fraction, methylenechloride fraction, ethylacetate fraction, butanol fraction, water fraction, or their mixture. The composition for improving skin condition is for skin whitening or anti-inflammation. The composition is formulated in a cosmetic composition or pharmaceutical composition.
    • 目的:提供含有改善皮肤状况的Aster subulatus提取物的组合物,以通过抗氧化,组织抑制和NO产生抑制来确保抗炎作用。 构成:用于改善皮肤状况的组合物含有Aster subulatus提取物或其溶剂级分作为活性成分。 通过粉碎干燥的Aster subulatu,将粉碎的Aster subulatu浸入70%乙醇中,搅拌2-3天,过滤,压缩浓缩和冷冻干燥获得Aster subulatu提取物。 溶剂馏分为乙醇提取物,己烷馏分,二氯甲烷馏分,乙酸乙酯馏分,丁醇馏分,水馏分或其混合物。 用于改善皮肤状况的组合物用于皮肤美白或抗炎。 将组合物配制在化妆品组合物或药物组合物中。
    • 6. 发明公开
    • 미백활성 및 항염활성을 나타내는 비룡추출물
    • 具有白色活性和抗炎活性的PONCIRUS聚氨酯提取物
    • KR1020080022315A
    • 2008-03-11
    • KR1020060085602
    • 2006-09-06
    • 재단법인 제주테크노파크
    • 김기옥한종헌김봉석고광효이주엽
    • A61K36/75A61P17/00A61P39/06
    • A61K36/75A61K8/97A61K2236/33A61K2236/37A61Q19/02Y10S514/844Y10S514/857
    • An extract of Poncirus polyandra is provided to whiten the skin by inhibiting activity of melanocyte and tyrosinase, inhibit oxidation by removing DPPH(1.1-diphenyl-2-picrylhydrazyl) radical and suppress inflammation without side effects, so that the extract is useful for skin whitening, and prevention and treatment of inflammatory disease. An extract of Poncirus polyandra having skin-whitening, anti-oxidative and anti-inflammatory effects is prepared by washing immature Poncirus polyandra with water, pulverizing the washed Poncirus polyandra, freeze-drying the pulverized Poncirus polyandra, dipping the pulverized product in 70% ethanol with agitation at room temperature for 2-3 days, filtering the extract of Poncirus polyandra, concentrating the filtered extract of Poncirus polyandra under reduced pressure, suspending the concentrates in distilled water, and extracting the suspension with hexane, ethylacetate and butanol sequentially. A composition for whitening the skin or preventing and treating inflammatory disease comprises the extract of Poncirus polyandra.
    • 通过抑制黑素细胞和酪氨酸酶的活性,通过除去DPPH(1.1-二苯基-2-苦基肼基)基团抑制氧化并抑制炎症而没有副作用,提供Pon irus提取物以增白皮肤,使得提取物可用于皮肤美白 ,以及预防和治疗炎症性疾病。 通过用水洗涤未成熟的Pon irus is is is is of of of of of of of of of of of of is is is is is is is ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol ethanol 在室温下搅拌2-3天,过滤茯苓提取物,减压浓缩滤液提取物,将浓缩物悬浮于蒸馏水中,并依次用己烷,乙酸乙酯和丁醇萃取悬浮液。 用于使皮肤美白或预防和治疗炎性疾病的组合物包括荚膜荚膜梭菌的提取物。
    • 7. 发明授权
    • 미백활성을 나타내는 노루참나물 추출물
    • 具有白色活性的PIMPINELLA KOMAROVII提取物
    • KR100791282B1
    • 2008-01-04
    • KR1020070019697
    • 2007-02-27
    • 재단법인 제주테크노파크
    • 김기옥한종헌김봉석강민철김미량고광효이주엽진호경엄병헌
    • A61K8/97A61Q19/02
    • A61K8/97A61K2236/333A61Q19/02Y10S514/844
    • An extract of Pimpinella komarovii is provided to secure excellent whitening effect and excellent antioxidative and anti-inflammatory activities. And a composition comprising the same as an effective ingredient is provided. An extract of Pimpinella komarovii with whitening activity is characterized in that it is prepared by hot-wind drying washed Pimpinella komarovii at a temperature of 40 deg.C, crushing the dried Pimpinella komarovii, dipping the crushed material of the Pimpinella komarovii in 70% ethanol with agitating for 2-3 days at room temperature, filtering the leachate using a filter to prepare a crude extract, and fractioning the crude extract using n-hexane, ethylacetate, and butanol in sequence. A composition for whitening, improving and preventing inflammatory diseases or antioxidizing comprises the extract of Pimpinella komarovii as an effective ingredient.
    • 提供Pimpinella komarovii的提取物以确保优异的美白效果和优异的抗氧化和抗炎活性。 并提供包含与有效成分相同的组合物。 具有增白活性的金丝桃提取物的特征在于通过在40℃的温度下热风干燥洗涤的Pimpinella komarovii制备,粉碎干燥的Pimpinella komarovii,将Pimpinella komarovii的破碎物质浸入70%乙醇 在室温下搅拌2-3天,使用过滤器过滤渗滤液以制备粗提物,并按顺序使用正己烷,乙酸乙酯和丁醇对粗提物进行分馏。 用于增白,改善和预防炎性疾病或抗氧化的组合物包括作为有效成分的Pimpinella komarovii的提取物。