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    • 2. 发明授权
    • 연 추출물을 함유하는 미백, 노화방지 및 주름개선용조성물
    • 包含NELUMBO NUCIFERA GAERTNER提取物的成分显示皮肤白化,抗衰老和抗皱活性
    • KR100828193B1
    • 2008-05-08
    • KR1020060108791
    • 2006-11-06
    • 박영준
    • 박성규장문석오명숙박완수김도림이병희양웅모김원남김향미박은화박영준
    • A61K36/62A61P17/00
    • A61K8/97A61K36/62A61K2236/33A61Q19/00A61Q19/02A61Q19/08A61Q19/10Y10S514/844Y10S514/846Y10S514/969
    • A composition comprising the extract of Nelumbo nucifera Gaertner is provided to inhibit melanin formation, activity of tyrosinase and production of lipid peroxide, and increase survival rate of keratinocyte and synthesis of collagen, so that the composition is useful for skin whitening, aging prevention and wrinkle improvement. A skin-whitening, anti-aging and anti-wrinkle composition comprises 0.0001-20 wt.% of the extract of Nelumbo nucifera Gaertner which is prepared by extracting with purified water, C1-C4 lower alcohol or propylene glycol, ethyl acetate, butylenes glycol, ether or chloroform and is a pharmaceutical composition having a formulation of cream, gel, patch, spray, ointment, plaster, lotion, liniment, pasta or cataplasma or a cosmetic composition having a formulation of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, nutrition cream, moisture cream, hand cream, foundation, essence, nutrition essence, pack, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion or body cleanser, wherein the daily dosage of the Nelumbo nucifera Gaertner extract is 0.0001-100 mg/kg.
    • 提供包含Nelumbo nucifera Gaertner提取物的组合物以抑制黑色素形成,酪氨酸酶的活性和脂质过氧化物的产生,并增加角质形成细胞的存活率和合成胶原,使得该组合物可用于皮肤美白,防老化和起皱 改进。 皮肤美白,抗衰老和抗皱组合物包含0.0001-20重量%的通过用纯水提取的Nelumbo nucifera Gaertner提取物,C1-C4低级醇或丙二醇,乙酸乙酯,丁二醇 ,醚或氯仿,并且是具有霜剂,凝胶剂,贴剂,喷雾剂,软膏剂,石膏剂,洗剂,搽剂,面食或粘膜制剂的制剂的药物组合物或具有皮肤洗剂,皮肤柔软剂,皮肤调色剂,收敛剂 ,乳液,乳液,保湿乳液,营养乳液,按摩霜,营养霜,保湿霜,护手霜,粉底,精华,营养精华,包装,肥皂,清洁泡沫,清洁乳液,清洁霜,身体乳液或身体清洁剂, 其中Nelumbo Nucifera Gaertner提取物的日剂量为0.0001-100mg / kg。