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    • 2. 发明授权
    • 연 추출물을 함유하는 미백, 노화방지 및 주름개선용조성물
    • 包含NELUMBO NUCIFERA GAERTNER提取物的成分显示皮肤白化,抗衰老和抗皱活性
    • KR100828193B1
    • 2008-05-08
    • KR1020060108791
    • 2006-11-06
    • 박영준
    • 박성규장문석오명숙박완수김도림이병희양웅모김원남김향미박은화박영준
    • A61K36/62A61P17/00
    • A61K8/97A61K36/62A61K2236/33A61Q19/00A61Q19/02A61Q19/08A61Q19/10Y10S514/844Y10S514/846Y10S514/969
    • A composition comprising the extract of Nelumbo nucifera Gaertner is provided to inhibit melanin formation, activity of tyrosinase and production of lipid peroxide, and increase survival rate of keratinocyte and synthesis of collagen, so that the composition is useful for skin whitening, aging prevention and wrinkle improvement. A skin-whitening, anti-aging and anti-wrinkle composition comprises 0.0001-20 wt.% of the extract of Nelumbo nucifera Gaertner which is prepared by extracting with purified water, C1-C4 lower alcohol or propylene glycol, ethyl acetate, butylenes glycol, ether or chloroform and is a pharmaceutical composition having a formulation of cream, gel, patch, spray, ointment, plaster, lotion, liniment, pasta or cataplasma or a cosmetic composition having a formulation of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, nutrition cream, moisture cream, hand cream, foundation, essence, nutrition essence, pack, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion or body cleanser, wherein the daily dosage of the Nelumbo nucifera Gaertner extract is 0.0001-100 mg/kg.
    • 提供包含Nelumbo nucifera Gaertner提取物的组合物以抑制黑色素形成,酪氨酸酶的活性和脂质过氧化物的产生,并增加角质形成细胞的存活率和合成胶原,使得该组合物可用于皮肤美白,防老化和起皱 改进。 皮肤美白,抗衰老和抗皱组合物包含0.0001-20重量%的通过用纯水提取的Nelumbo nucifera Gaertner提取物,C1-C4低级醇或丙二醇,乙酸乙酯,丁二醇 ,醚或氯仿,并且是具有霜剂,凝胶剂,贴剂,喷雾剂,软膏剂,石膏剂,洗剂,搽剂,面食或粘膜制剂的制剂的药物组合物或具有皮肤洗剂,皮肤柔软剂,皮肤调色剂,收敛剂 ,乳液,乳液,保湿乳液,营养乳液,按摩霜,营养霜,保湿霜,护手霜,粉底,精华,营养精华,包装,肥皂,清洁泡沫,清洁乳液,清洁霜,身体乳液或身体清洁剂, 其中Nelumbo Nucifera Gaertner提取物的日剂量为0.0001-100mg / kg。
    • 6. 发明公开
    • 줄기세포 분화능 개선용 조성물
    • 用于增强干细胞分化的组合物
    • KR1020130079673A
    • 2013-07-11
    • KR1020110146634
    • 2011-12-30
    • 박영준
    • 박영준김도림
    • A61K36/296A61P35/00
    • PURPOSE: A composition for improving stem cell differentiation potency is provided to produce a large amount of stem cells, especially multipotent mesenchymal stem cells by effectively improving the differentiation rate of the stem cells and to be used in various clinical fields. CONSTITUTION: A composition for improving stem cell differentiation potency contains an Epimedii herba extract. The extract is prepared from Epimedii herba using water, methanol, ethanol, or a mixture thereof. The stem cells are totipotent stem cells or multipotent stem cells. The stem cells are mutipotent mesenchymal stem cells, multipotent hematopoietic stem cells, multipotent nerve stem cells, multipotent liver stem cells, multipotent pancreatic stem cells, or multipotent epidermal stem cells. A method for improving differentiation potency of the stem cells comprises the step of treating the stem cells with the extract.
    • 目的:提供一种改善干细胞分化效能的组合物,通过有效提高干细胞的分化率,并用于各种临床领域,产生大量的干细胞,特别是多能间充质干细胞。 构成:用于改善干细胞分化能力的组合物含有淫羊藿提取物。 使用水,甲醇,乙醇或其混合物从淫羊藿制备提取物。 干细胞是全能干细胞或多能干细胞。 干细胞是多能间充质干细胞,多潜能造血干细胞,多潜能神经干细胞,多能肝干细胞,多能胰腺干细胞或多能表皮干细胞。 提高干细胞分化能力的方法包括用提取物处理干细胞的步骤。
    • 7. 发明公开
    • 줄기세포 증식능 및 분화능 개선용 조성물
    • 用于增强干细胞增殖和分化的组合物
    • KR1020130077949A
    • 2013-07-10
    • KR1020110146624
    • 2011-12-30
    • 박영준
    • 박영준김도림
    • A61K36/714A61P35/00
    • A61K36/714A61K9/14A61K2236/30A61K2236/51
    • PURPOSE: A composition for improving proliferation and differentiation potency of stem cells is provided to produce a large amount of the stem cells, especially multipotent stem cells by effectively improving proliferation rate and differentiation rate of the stem cells, and to be used in various clinical fields by increasing the use of the multipotent stem cells with superior safety than embryonic stem cells. CONSTITUTION: A composition for improving proliferation and differentiation potency of stem cells contains an Aconiti Lateralis Preparata Radix extract. The extract is prepared by treating Aconiti Lateralis Preparata Radix with water, methanol, ethanol, or a mixture thereof. The stem cells are totipotent stem cells or multipotent stem cells. A method for improving proliferation and differentiation potency of the stem cells comprises the step of treating the stem cells with the extract.
    • 目的:提供一种改善干细胞增殖和分化能力的组合物,通过有效提高干细胞的增殖率和分化率,产生大量的干细胞,特别是多能干细胞,并用于各种临床领域 通过增加使用比胚胎干细胞更优越的安全性的多能干细胞的使用。 构成:用于改善干细胞增殖和分化能力的组合物含有Aconiti Lateralis Preparata Radix提取物。 通过用水,甲醇,乙醇或其混合物处理Aconiti Lateralis Preparata Radix制备提取物。 干细胞是全能干细胞或多能干细胞。 改善干细胞增殖和分化能力的方法包括用提取物处理干细胞的步骤。
    • 8. 发明公开
    • 줄기세포 분화능 개선용 조성물
    • 用于增强干细胞分化的组合物
    • KR1020130077944A
    • 2013-07-10
    • KR1020110146618
    • 2011-12-30
    • 박영준
    • 박영준김도림
    • A61K36/23A61P35/00
    • A61K36/23A61K9/14A61K2236/30A61K2236/51
    • PURPOSE: A composition for improving stem cell differentiation potency is provided to produce a large amount of stem cells, especially multipotent mesenchymal stem cells by effectively improving differentiation rate of the stem cells, and to be used in various clinical fields by increasing the use of the multipotent stem cells with superior safety than embryonic stem cells. CONSTITUTION: A composition for improving stem cell differentiation potency contains a Cnidi Fructus extract which is prepared by treating Cnidi Fructus with water, methanol, ethanol, or a mixture thereof. The step cell is totipotent stem cells or multipotent stem cells. A method for improving stem cell differentiation potency comprises the step of treating the stem cells with the extract.
    • 目的:提供一种提高干细胞分化效能的组合物,通过有效提高干细胞分化率,产生大量干细胞,特别是多能间充质干细胞,并通过增加使用 多能干细胞比胚胎干细胞具有更好的安全性。 构成:用于提高干细胞分化效能的组合物含有Cnidi Fructus提取物,其通过用水,甲醇,乙醇或其混合物处理Cnidi Fructus来制备。 步骤细胞是全能干细胞或多能干细胞。 提高干细胞分化能力的方法包括用提取物处理干细胞的步骤。