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    • 4. 发明公开
    • 치과용 차폐막
    • 牙膏膜
    • KR1020130033826A
    • 2013-04-04
    • KR1020110097751
    • 2011-09-27
    • 대한민국(농촌진흥청장)
    • 권해용조유영류강선이광길강석우김성곤
    • A61K31/047A61K38/01A61C5/00A61P1/02
    • PURPOSE: An antibacterial dental membrane is provided to ensure alkaline phosphatase activity in osteoblast, and to improve bond generation in a lesion. CONSTITUTION: A dental membrane contains 0.01-10 wt% of 4-hexylresorcinol, and 90-99.99 wt% of silk proteins. The silk protein is silk fibroin. A method for manufacturing the dental membrane comprises: a step of dissolving the silk fibroin in an ethanol solution containing a salt, and removing the salt and ethanol to prepare a silk fibroin solution; a step of dissolving 4-hexylresorcinol in ethanol and preparing 4-hexylresorcinol ethanol solution; a step of mixing the silk fibroin solution and the 4-hexylresorcinol ethanol solution, and comprising a dental membrane composition; and a step of pouring the dental membrane composition into a container and drying. [Reference numerals] (AA) Control group without applying a membrane; (BB) Experimental group with applying the membrane of the present invention composed of 3% hexylresorcinol and remaining amount of silk fibroin(an arrow indicates a remaining dental membrane);
    • 目的:提供抗菌牙膜,以确保成骨细胞中的碱性磷酸酶活性,并改善病变中的结合产生。 构成:牙膜含有0.01-10重量%的4-己基间苯二酚和90-99.99重量%的丝蛋白。 丝蛋白是丝素蛋白。 一种牙科膜的制造方法,其特征在于,包括将丝素蛋白溶解在含有盐的乙醇溶液中,除去盐和乙醇以制备丝素蛋白溶液的步骤; 将4-己基间苯二酚溶解在乙醇中并制备4-己基间苯二酚乙醇溶液的步骤; 将丝素蛋白溶液与4-己基间苯二酚乙醇溶液混合并包含牙膜组合物的步骤; 以及将牙膜组合物倒入容器中并干燥的步骤。 (标号)(AA)不涂膜的对照组; (BB)使用由3%己基间苯二酚构成的本发明的膜和剩余量的丝素蛋白(箭头表示剩余的牙膜)的实验组。