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1. 发明专利

JP2014238384A ラマン定量用バイオチップ有权
标题翻译：用于拉曼量化的生物技术
公开(公告)号：JP2014238384A
公开(公告)日：2014-12-18
申请号：JP2013199380
申请日：2013-09-26
申请人：有限会社マイテック , Maitekku:Kk , 伊藤寛晃 , Ito Hiroaki , 伊藤寛晃
发明人： HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： G01N21/65 , G01N33/543 , G01N33/574
CPC分类号： G01N21/658 , C01G5/00 , C01P2002/60 , G01N33/5438 , G01N33/553 , G01N33/57496
摘要：【課題】癌細胞由来の遊離DNAを測定するためのラマン定量用バイオチップを提供する。【解決手段】銀ハロゲン化物又はハロゲンを含む銀酸化物の複合針状ナノ結晶群を含み、水中で負電荷を示し、正電荷の癌関連物質を吸着して電荷移動錯体と形成可能であるとともに光照射により銀粒子を析出可能で、レーザー照射により表面プラズモン増強効果が得られる領域を有するバイオチップを提供する。このバイオチップは水中でガン由来遊離DNAを選択的に吸着可能であるとともに、レーザー光照射により吸着した遊離DNAの表面増強ラマンスペクトル(SERS)を検出可能である。【選択図】図9
摘要翻译：要解决的问题：提供用于测量来自癌细胞的游离DNA的拉曼定量的生物芯片。解决方案：生物芯片包含卤化银或含有卤素的氧化银的复合针状纳米晶体组，在水中呈现负电荷，可形成通过吸附正电荷的癌相关物质的电荷转移络合物可以通过光照射沉淀银颗粒，并且具有通过激光照射获得表面等离子体增强效果的区域。生物芯片可以选择性地吸附水中衍生自癌症的游离DNA，并且可以检测通过激光束照射吸附的游离DNA的表面增强拉曼光谱（SERS）。

2. 发明专利

JP2012059469A Dye-sensitized quantum dot solar cell 审中-公开
标题翻译： DYE-SENSITIZED QUANTUM DOT SOLAR CELL
公开(公告)号：JP2012059469A
公开(公告)日：2012-03-22
申请号：JP2010200227
申请日：2010-09-07
申请人： Maitekku:Kk , 有限会社マイテック
发明人： HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： H01M14/00 , H01L31/04
CPC分类号： Y02E10/542 , Y02P70/521
摘要： PROBLEM TO BE SOLVED: To provide a dye-sensitized quantum dot solar cell.SOLUTION: The dye-sensitized quantum dot solar cell includes a cathode electrode 10 and an anode electrode 30 which are disposed via an electrolyte solution 20 which contains redox species, where the cathode electrode 10 comes with a complex crystal film 13 having formed therein quantum dots comprised of metal nano-clusters capable of Plasmon resonance, thereby providing a high photoelectric conversion efficiency thanks to the quantum dots. The Plasmon resonance metal thin-film comprises a metal thin-film or a metal mesh having light transmissivity and complex crystal obtained by depositing the metal nano-clusters together with metal complex as quantum dots on the metal thin-film or the metal mesh, thereby serving also as a transparent conductive electrode.
摘要翻译：要解决的问题：提供染料敏化量子点太阳能电池。解决方案：染料敏化量子点太阳能电池包括阴极电极10和阳极电极30，其经由含有氧化还原物质的电解质溶液20设置，其中阴极10带有形成的复合晶体膜13 其中的量子点由能够进行等离子体共振的金属纳米簇组成，从而通过量子点提供高的光电转换效率。等离子体共振金属薄膜包括具有透光性的金属薄膜或金属网，并且通过在金属薄膜或金属网上将金属纳米簇与金属络合物一起作为量子点沉积而获得的复合晶体，由此也用作透明导电电极。版权所有（C）2012，JPO＆INPIT

3. 发明专利

JP2009281845A Substrate for surface reinforcing raman spectral analysis 审中-公开
标题翻译：表面增强拉曼光谱分析的基板
公开(公告)号：JP2009281845A
公开(公告)日：2009-12-03
申请号：JP2008133807
申请日：2008-05-22
申请人： Maitekku:Kk , 有限会社マイテック
发明人： HASEGAWA KATSUYUKI
IPC分类号： G01N21/65
摘要： PROBLEM TO BE SOLVED: To simply and in a short time enable mass production of a substrate for surface reinforcing Raman spectral analysis of high sensitivity, which can be preserved for a long period of time and has high reproducibility. SOLUTION: A liquid composition, wherein nano-particles of gold, silver, copper or a platinum group metal and a thermoplastic resin nano-powder are dispersed to be mixed with each other, is applied to the surface of a thermoplastic resin substrate and the coated substrate is heated and pressed at a temperature lower than the melting temperature of the metal nano-particles to disperse and fix the nano-particles on the substrate, thereby producing the substrate for surface reinforcing Raman spectral analysis used in an exposed state. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：为了简单且短时间，可以批量生产用于高灵敏度的表面增强拉曼光谱分析的基板，其可以长期保存并具有高再现性。解决方案：将金，银，铜或铂族金属的纳米颗粒和热塑性树脂纳米粉末分散以彼此混合的液体组合物施加到热塑性树脂基材的表面在低于金属纳米粒子的熔融温度的温度下对被涂布的基材进行加热加压，将纳米粒子分散并固定在基板上，由此制造用于暴露状态的表面增强拉曼光谱分析用基板。版权所有（C）2010，JPO＆INPIT

4. 发明专利

JP2014238382A 癌関連物質の定量方法有权
标题翻译：癌相关物质的定量方法
公开(公告)号：JP2014238382A
公开(公告)日：2014-12-18
申请号：JP2013191224
申请日：2013-09-14
申请人：有限会社マイテック , Maitekku:Kk , 寛晃伊藤 , Hiroaki Ito , 寛晃伊藤
发明人： ITO HIROAKI , HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： G01N21/65 , G01N33/543
CPC分类号： G01N21/658 , C01G5/00 , C01P2002/60 , G01N33/5438 , G01N33/553 , G01N33/57496
摘要：【課題】癌細胞由来の遊離DNA等の癌関連物質のラマン定量分析方法の提供すること。【解決手段】銀ハロゲン化物又はハロゲンを含む銀酸化物の複合針状ナノ結晶群を含む領域を有するバイオチップを用意し、該バイオチップの針状ナノ結晶群領域に血清又は生体試料液を滴下し、試料中の正電荷を有する癌関連物質を選択的に吸着し、吸着した癌関連物質に対しレーザー照射してそこからのラマン散乱光を検知する工程を含み、レーザー光照射により吸着した遊離DNAの表面増強ラマン散乱(SERS)中のクロマチンピークを検出して癌疾病を判定する。【選択図】図9
摘要翻译：要解决的问题：提供一种癌症相关物质如衍生自癌细胞的游离DNA的拉曼定量分析方法。解决方案：生物芯片具有包含卤化银或含有卤素的氧化银的复合针状纳米晶体组的区域。拉曼定量分析方法包括将血清或有机体样品液滴入生物芯片的针状纳米晶体区域的步骤，选择性地吸附样品中具有正电荷的癌相关物质，并且将被吸附的癌症相关物质照射激光检测拉曼散射光; 并检测通过激光束照射吸附的游离DNA的表面增强拉曼散射（SERS）中的染色质峰，以确定癌性疾病。

5. 发明专利

JP2013133475A Method for producing metal complex quantum crystal 有权
标题翻译：生产金属复合材料晶体的方法
公开(公告)号：JP2013133475A
公开(公告)日：2013-07-08
申请号：JP2011282474
申请日：2011-12-23
申请人： Maitekku:Kk , 有限会社マイテック
发明人： HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： C25D15/02 , C25D21/12
摘要： PROBLEM TO BE SOLVED: To provide a method for depositing a metal complex quantum crystal by an electrode reaction on a metal substrate or a particulate carrier metal from an aqueous solution of a metal complex.SOLUTION: The method includes: preparing a dilute aqueous metal complex solution, harmonizing the electrode potentials of an electrode reaction by controlling the stability constant of the metal complex and the electrode potential of a carrier metal, bringing the carrier metal into contact with the dilute aqueous metal complex solution, depositing the metal complex together with a nano-cluster metal on the carrier metal from the dilute aqueous metal complex solution, and stopping the deposition of a complex crystal by releasing the contact of the aqueous solution with the carrier metal. It is possible to use a dilute aqueous silver complex solution of 500-2,000 ppm. It is desirable that the dilute aqueous solution is prepared by selecting a silver complex salt of a stability constant of 8 or more.
摘要翻译：要解决的问题：提供一种通过电极反应在金属基材或颗粒状载体金属上从金属络合物的水溶液中沉积金属络合物量子晶体的方法。溶液：该方法包括：制备稀的金属络合物溶液，通过控制金属络合物的稳定常数和载体金属的电极电位来调节电极反应的电极电位，使载体金属与稀释的金属络合物溶液接触，将金属络合物与纳米从金属络合物溶液稀释载体金属上的聚集体金属，通过释放水溶液与载体金属的接触来停止复合结晶的沉积。可以使用500-2,000ppm的稀的水银络合物溶液。优选通过选择稳定常数为8以上的银络盐来制备稀水溶液。

6. 发明专利

JP2009270380A 60 min heatproof building material and its manufacturing method 审中-公开
标题翻译： 60分钟耐热建筑材料及其制造方法
公开(公告)号：JP2009270380A
公开(公告)日：2009-11-19
申请号：JP2008123540
申请日：2008-05-09
申请人： Maitekku:Kk , 有限会社マイテック
发明人： HASEGAWA KATSUYUKI
IPC分类号： E04B1/94
CPC分类号： C04B28/04 , C04B28/14 , C04B41/009 , C04B41/52 , C04B2111/00612 , C04B2111/28 , C04B14/303 , C04B22/064 , C04B22/066 , C04B24/24 , C04B40/024 , C04B28/00 , C04B41/5079 , C04B41/5085
摘要： PROBLEM TO BE SOLVED: To provide a fire resistant building material capable of passing a 60 min fire resistance test and being mass-producible.
SOLUTION: This 60 min heatproof building material is composed of a core material (a) made of (a-1) a composite resin sheet constituted by heating, compressing, and molding composite chips comprising 85-70 wt.% of a hydration metal compound and 15-30 wt.% of a thermoplastic resin or (a-2) a composite mortar sheet formed by mixing the composite chips comprising 85-70 wt.% of the hydration metal compound and 15-30 wt.% of the thermoplastic resin with a wall material such as cement or gypsum or the like, an intermediate layer (b) composed of fiber nets provided on both surfaces of the core material and nipping and holding the core material, and an outer layer (c) composed of an inorganic fire resistant layer formed by the cement or the gypsum composition formed on one surface or both surfaces of the core matrial through the fiber nets. This heatproof building material has the physical properties causing no weight loss of 30% or more in a noncombustibility test and no collapse due to burning of the core material in the 60 min fire resistance test.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供能够通过60分钟耐火试验并且可批量生产的耐火建筑材料。解决方案：这种60分钟的耐热建筑材料由（a-1）制成的芯材（a）组成，复合树脂片是通过加热，压缩和模塑复合材料片而构成的，复合材料片包含85-70重量％水合金属化合物和15-30重量％的热塑性树脂或（a-2）通过将包含85-70重量％的水合金属化合物和15-30重量％的水合金属化合物的复合材料芯片具有诸如水泥或石膏等壁材料的热塑性树脂，由芯材的两个表面上设置并夹持并保持芯材的纤维网构成的中间层（b），以及外层（c）由通过纤维网在芯体的一个表面或两个表面上形成的水泥或石膏组合物形成的无机耐火层。这种耐热建筑材料具有在不燃性试验中不造成重量损失30％以上的物理性能，并且在60分钟耐火试验中不会由于芯材料的燃烧而导致塌陷。版权所有（C）2010，JPO＆INPIT

7. 发明专利

JP2014010034A Endotoxin measurement method and raman spectroscopy measurement board for endotoxin 审中-公开
标题翻译：内毒素测量方法和内毒素拉曼光谱测量板
公开(公告)号：JP2014010034A
公开(公告)日：2014-01-20
申请号：JP2012146381
申请日：2012-06-29
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所 , Kwansei Gakuin Univ , 学校法人関西学院 , Maitekku:Kk , 有限会社マイテック
发明人： FUKUOKA SATOSHI , ITO TAMITAKE , YAMAMOTO YUKO , OZAKI YUKIHIRO , KITAHAMA YASUTAKA , HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： G01N33/579 , G01N21/27 , G01N33/543 , G01N33/553
摘要： PROBLEM TO BE SOLVED: To provide an endotoxin measurement method capable of facilitating a measurement operation by reducing the used amount of reagent in limulus testing and shortening measurement time, and a measurement board used for the same.SOLUTION: A measurement device includes a plasmon metal quantum crystal and a limulus reagent (LAL reagent) for limulus testing, and endotoxin is measured using the measurement device by Raman spectroscopy. The plasmon metal quantum crystal is formed on the metal surface by using the LAL reagent. By using this, reaction with a small amount of endotoxin is detected by Raman spectroscopy. Thus, by an operation simpler compared with conventionally performed endotoxin measurement based on gelation, turbidimetry, or colorimetric, a measurement result is quickly obtained with the used amount of reagent set equal to or less than 1/1000 and measurement time set to several minutes equal to or less than 1/10.
摘要翻译：要解决的问题：提供能够通过减少鲎试验中的试剂的使用量和缩短测定时间来促进测定操作的内毒素测定方法及其使用的测定板。测定装置包括等离子体金属量子晶体和用于鲎测试的鲎试剂（LAL试剂），并且使用拉曼光谱测量装置测量内毒素。通过使用LAL试剂在金属表面上形成等离子体金属量子晶体。通过使用该方法，通过拉曼光谱法检测与少量内毒素的反应。因此，通过与基于凝胶化，比浊法或比色法的常规进行的内毒素测定相比较的操作更简单，随着试剂组的使用量等于或小于1/1000并且测量时间设定为几分钟，快速获得测量结果等于至1/10以下。

8. 发明专利

JP2010203973A Measuring method of surface enhanced raman scattering 审中-公开
标题翻译：表面增强拉曼散射测量方法
公开(公告)号：JP2010203973A
公开(公告)日：2010-09-16
申请号：JP2009051104
申请日：2009-03-04
申请人： Hyogo Prefecture , Maitekku:Kk , 兵庫県 , 有限会社マイテック
发明人： UCHIUMI YUICHI , HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： G01N21/65
CPC分类号： G01N21/658
摘要： PROBLEM TO BE SOLVED: To propose a measuring method of SERS activity having high reproducibility, and to enable stable measurement.
SOLUTION: Concerning colloidal solution of metal nanoparticles having at least one of surface enhanced Raman activity function, the metal nanoparticle colloidal solution containing a detection sample is dropped onto a substrate having or setting a higher electrode potential than a metal electrode potential of a colloidal metal, and molecules adsorbed on the metal nanoparticle surface is irradiated with prescribed laser light in an aggregation process on the substrate of the metal nanoparticles, to thereby measure Raman scattered light generated from adsorbed molecules.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提出具有高再现性的SERS活性的测量方法，并且能够稳定测量。解决方案：关于具有表面增强拉曼活性功能中的至少一种的金属纳米颗粒的胶体溶液，将含有检测样品的金属纳米颗粒胶体溶液滴落到具有比其电极电位的电极电位高或设置为高于胶体金属和吸附在金属纳米颗粒表面上的分子以规定的激光在金属纳米颗粒的基板上的聚集过程中照射，从而测量由吸附分子产生的拉曼散射光。版权所有（C）2010，JPO＆INPIT

9. 发明专利

PH12019502307A1 RAMAN QUANTIFICATION METHOD OF CANCER-RELATED SUBSTANCE 未知
公开(公告)号：PH12019502307A1
公开(公告)日：2021-02-15
申请号：PH12019502307
申请日：2019-10-08
申请人： MYTECH CO LTD , ITO HIROAKI
发明人： ITO HIROAKI , HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： G01N33/543 , G01N21/65 , G01N33/68
摘要： [Problem] To provide a Raman quantification method for measuring cancer cell-derived free DNA. [Solution] This Raman quantification method is characterized by involving a step for preparing a biochip having a mesocrystal region of a silver oxide containing peroxide silver, adding blood serum or biological sample solution dropwise onto the mesocrystal region of said biochip, selectively adsorbing the cancer-related substance having a positive charge in the sample, irradiating the adsorbed cancer-related substance with a laser and detecting Raman scattering therefrom, wherein the cancer illness is determined on the basis of the intensity of the surface-enhanced Raman spectroscopy (SERS). In the carbon-specific D band and G band in the Raman scattering spectrum, a characteristic peak spectrum of the cancer-related substance can be detected in the proximity of the methyl group-characteristic 2900cm-1.

10. 发明专利

AU2014263556A1 Raman quantification method of cancer-related substance 未知
公开(公告)号：AU2014263556A1
公开(公告)日：2015-11-26
申请号：AU2014263556
申请日：2014-05-08
申请人： ITO HIROAKI , MYTECH CO LTD
发明人： ITO HIROAKI , HASEGAWA YUKI , HASEGAWA KATSUYUKI
IPC分类号： G01N21/65 , G01N33/543 , G01N33/68
摘要： [Problem] To provide a Raman quantification method for measuring cancer cell-derived free DNA. [Solution] This Raman quantification method is characterized by involving a step for preparing a biochip having a mesocrystal region of a silver oxide containing peroxide silver, adding blood serum or biological sample solution dropwise onto the mesocrystal region of said biochip, selectively adsorbing the cancer-related substance having a positive charge in the sample, irradiating the adsorbed cancer-related substance with a laser and detecting Raman scattering therefrom, wherein the cancer illness is determined on the basis of the intensity of the surface-enhanced Raman spectroscopy (SERS). In the carbon-specific D band and G band in the Raman scattering spectrum, a characteristic peak spectrum of the cancer-related substance can be detected in the proximity of the methyl group-characteristic 2900cm

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