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    • 1. 发明申请
    • LOCAL ADMINISTRATION OF CHICKEN YOLK IMMUNE GLOBULINS (IgY) TO TREAT AND PREVENT FUNGAL INFECTIONS
    • 鸡肉免疫球蛋白(IgY)的局部施用以治疗和预防真菌感染
    • WO2009027470A1
    • 2009-03-05
    • PCT/EP2008/061309
    • 2008-08-28
    • ÅGERUP, BengtLARSSON, AndersKOLLBERG, Hans
    • LARSSON, AndersKOLLBERG, Hans
    • C07K16/02C07K16/14A61K39/395A61P31/10
    • C07K16/02A61K9/0034A61K9/0056A61K9/19A61K2039/505C07K16/14C07K2317/11C07K2317/23
    • The present invention relates to a composition comprising IgY antibodies against at least two different fungi, the use of the composition for the preparation of a pharmaceutical especially for prophylaxis and/or therapy of all kinds of fungal infections, such as conditions caused by organisms belonging to the Candida genus or Aspergillus genus, especially of fungi that are less sensitive to antimycotica and a diagnotstic method using the IgY antibodies. Further it relates to immunisation of birds with a combination of at least two different species of fungi to the Candida genus or Aspergillus genus and a diagnostic method for fungi. It also relates to relates to a novel method for treatment and/or prophylaxis of fungal infections, especially infections by fungi which have lowered sensitivity or resistance to antimycotics. The method is both safe and effective. This is achieved by using IgY directed against fungi, in particular against Candida species, which have a lowered sensitivity or resistance against antimycotics. The specific IgY has been obtained by hyper immunising birds with one or several fungi as antigen in order to stimulate the production of immune globulins (IgY) against such fungi. The present invention also relates to a pharmaceutical product from eggs of birds containing immune globulin or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
    • 本发明涉及包含针对至少两种不同真菌的IgY抗体的组合物,所述组合物用于制备药物,特别是用于预防和/或治疗各种真菌感染的用途,所述真菌感染例如由属于 假丝酵母属或曲霉属,特别是对抗真菌敏感性较差的真菌,以及使用IgY抗体的诊断方法。 此外,它涉及具有至少两种不同种类的真菌与假丝酵母属或曲霉属的组合的鸟的免疫和真菌的诊断方法。 本发明还涉及用于治疗和/或预防真菌感染,特别是具有降低的抗真菌性或抗真菌性的真菌感染的新方法。 该方法既安全又有效。 这是通过使用针对真菌,特别是抗假丝酵母属物种的IgY来实现的,其具有降低的敏感性或抗抗生素抗性。 通过用一种或几种真菌作为抗原的超免疫鸟类获得特异性IgY,以刺激针对这种真菌的免疫球蛋白(IgY)的产生。 本发明还涉及包含免疫球蛋白或其片段的鸟卵的药物产品,其可与其他制剂,营养物质或药物组合以同时,分开或依次用于预防或治疗新生儿胃肠道感染 。
    • 2. 发明申请
    • USE OF AVIAN ANTIBODIES
    • 使用AVIAN抗体
    • WO2004067035A1
    • 2004-08-12
    • PCT/SE2004/000133
    • 2004-01-30
    • IMMUN SYSTEM I.M.S. ABLARSSON, AndersKOLLBERG, Hans
    • LARSSON, AndersKOLLBERG, Hans
    • A61K39/395
    • C07K16/1228A61K2039/505C07K2317/11C07K2317/23
    • The present invention relates to a novel method for treatment and prophylaxis of infections, especially enteric infections, in newborns, which is both safe and effective. This is achieved by using IgY directed against microbes, in particular against Enterobacter cloacae, which have been obtained by hyperimmunising birds with an antigen (microbe) in order to stimulate the production of immunoglobulines (IgY) against such microbe. The present invention also relates to a pharmaceutical product from eggs of birds containing immunoglobuline or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
    • 本发明涉及一种治疗和预防新生儿感染特别是肠道感染的新方法,既安全又有效。 这是通过使用针对微生物(特别是针对阴沟肠杆菌)的IgY来实现的,所述细菌已经通过用抗原(微生物)超免疫鸟获得,以刺激针对这种微生物产生免疫球蛋白(IgY)。 本发明还涉及含有免疫球蛋白或其片段的鸟卵的药物产品,其可与用于预防或治疗新生儿胃肠道感染的其他制剂,营养物或药物同时,分开或顺序使用。
    • 10. 发明申请
    • WATER PURIFIER
    • 水净化器
    • WO2006062467A1
    • 2006-06-15
    • PCT/SE2005/001837
    • 2005-12-06
    • GLOW ABLARSSON, Anders
    • LARSSON, Anders
    • C02F1/32
    • C02F9/005C02F1/283C02F1/325C02F2201/3223C02F2201/326
    • The present invention relates to a water purifier for the purification of pressurized water, said water purifier comprising a filter chamber (16) with a cylindrical adsorption filter (17), a UV chamber (19) that is provided inside the adsorption filter (17), an incoming water intake (15) to the filter chamber (16), a spout (20) emanating from the filter chamber (16) for the discharge of water from the filter chamber (16), a space (11) laterally displaced relative to the filter chamber (16), components for the control of the function of the water purifier being received in said space (11), an upper demountable part (3) and a lower demountable part (5). It is significant of the water purifier according to the present invention that the connection of the incoming water is made to a central main portion (1) of the water purifier, that the discharge of the purified water is effected from the central main portion (1), and that the central main portion (1) is located between the demountable parts (3, 5).
    • 本发明涉及一种用于净化加压水的净水器,所述净水器包括具有圆柱形吸附过滤器(17)的过滤室(16),设置在吸附过滤器(17)内部的UV室(19) ,过滤室(16)的入水入口(15),从过滤室(16)发出的用于从过滤室(16)排放水的喷口(20),横向移位相对的空间 到所述过滤室(16),用于控制所述空气(11)中的净水器的功能的部件,上部可拆卸部件(3)和下部可拆卸部件(5)。 根据本发明的净水器重要的是,进水的连接与净水器的中心主体部分(1)相连,净化水的排出是从中央主体部分(1) ),并且中心主要部分(1)位于可拆卸部分(3,5)之间。