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1. 发明申请

WO2006072091A3 LINEAR MOVING CAPACITIVE SENSOR TWIN COLUMN ELECTRONIC HEIGHT GAUGE 审中-公开
标题翻译：线性移动电容传感器双列电子高度计
公开(公告)号：WO2006072091A3
公开(公告)日：2006-12-21
申请号：PCT/US2005047651
申请日：2005-12-20
申请人： ZHANG YANCHEN
发明人： ZHANG YANCHEN
IPC分类号： G01B7/16 , G01L1/04
CPC分类号： G01B7/082
摘要： The invention is a height gauge which includes a first (5) and a second column (8), a display unit (3) with a cover, a measuring scriber (9), a fixed capacitance sensor and a linear moving capacitance sensor. The fixed capacitance sensor is located on a flat surface having a length equivalent to the length of column 1 , the linear moving capacitance sensor is located inside the display unit cover positioned to a face the fixed capacitance sensor. This sensor transfer system results in high accuracy of measurements. Als since the sensors do not make direct physical when the gauge is operating in upward movement, there is no wear and tear damage their component part, leading to a longer life of use with stability in accurate measurement and repeatability. Because the measuri system is comparatively simple, and easy to assemble and service and maintain compared to the existing rotary capacitive sensor electronics height gauge that exist on the market, the overall cost of production and maintenance is minimized. On the second column, a simple rack and gear system is added. These gears of column 2 are connected to a hand wheel located on the rear of the display unit.
摘要翻译：本发明是包括第一（5）和第二列（8）的高度计，具有盖的显示单元（3），测量划线器（9），固定电容传感器和线性移动电容传感器。固定电容传感器位于具有与列1长度相等的长度的平坦表面上，线性移动电容传感器位于与固定电容传感器相对置的显示单元盖内。该传感器传输系统产生高精度的测量。 Als，因为传感器在测量仪向上运动时不会直接物理，所以没有磨损和损坏其组成部分，导致使用寿命更长，在精确测量和重复性方面具有稳定性。由于测量系统相对简单，易于组装和维护，与目前市场上存在的旋转电容式传感器电子高度计相比，生产和维护的总体成本最小化。在第二列中，添加了一个简单的齿条和齿轮系统。列2的这些齿轮连接到位于显示单元后部的手轮。

2. 发明申请

WO2006002099A3 FACTOR XA INHIBITORS 审中-公开
公开(公告)号：WO2006002099A3
公开(公告)日：2006-01-05
申请号：PCT/US2005/021817
申请日：2005-06-20
申请人： MILLENNIUM PHARMACEUTICALS, INC. , ZHU, Bing-Yan , BAUER, Shawn M. , JIA, Zhaozhong J. , PROBST, Gary D. , ZHANG, Yanchen , SCARBOROUGH, Robert M.
发明人： ZHU, Bing-Yan , BAUER, Shawn M. , JIA, Zhaozhong J. , PROBST, Gary D. , ZHANG, Yanchen , SCARBOROUGH, Robert M.
IPC分类号： C07D207/09 , C07D207/10 , A61K31/4025
摘要： The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.

3. 发明申请

WO2011037731A1 BORON CONTAINING SMALL MOLECULES 审中-公开
标题翻译：含有BORON的小分子
公开(公告)号：WO2011037731A1
公开(公告)日：2011-03-31
申请号：PCT/US2010/047355
申请日：2010-08-31
申请人： ANACOR PHARMACEUTICALS, INC. , HERNANDEZ, Vincent, S. , DING, Charles , PLATTNER, Jacob , ALLEY, Michael, Richard Kevin , ZHANG, Yong-Kang , ZHANG, Yanchen
发明人： HERNANDEZ, Vincent, S. , DING, Charles , PLATTNER, Jacob , ALLEY, Michael, Richard Kevin , ZHANG, Yong-Kang , ZHANG, Yanchen
IPC分类号： C07F5/02 , A61K31/69
CPC分类号： C07F5/025
摘要： This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了可用于治疗细菌感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。

4. 发明申请

WO2007095588A1 PI-3 KINASE INHIBITORS AND METHODS OF THEIR USE 审中-公开
标题翻译： PI-3激酶抑制剂及其使用方法
公开(公告)号：WO2007095588A1
公开(公告)日：2007-08-23
申请号：PCT/US2007/062157
申请日：2007-02-14
申请人： NOVARTIS AG , NI, Zhi-jie , PECCHI, Sabina , BURGER, Matthew , HAN, Wooseok , SMITH, Aaron , ATALLAH, Gordana , BARTULIS, Sarah , FRAZIER, Kelly , VERHAGEN, Joelle , ZHANG, Yanchen , IWANOWICZ, Ed , HENDRICKSON, Tom , KNAPP, Mark , MERRITT, Hanne , VOLIVA, Charles , WIESMANN, Marion , LEGRAND, Darren Mark , BRUCE, Ian , DALE, James , LAN, Jiong , LEVINE, Barry , COSTALES, Abran , LIU, Jie , PICK, Teresa , MENEZES, Daniel
发明人： NI, Zhi-jie , PECCHI, Sabina , BURGER, Matthew , HAN, Wooseok , SMITH, Aaron , ATALLAH, Gordana , BARTULIS, Sarah , FRAZIER, Kelly , VERHAGEN, Joelle , ZHANG, Yanchen , IWANOWICZ, Ed , HENDRICKSON, Tom , KNAPP, Mark , MERRITT, Hanne , VOLIVA, Charles , WIESMANN, Marion , LEGRAND, Darren Mark , BRUCE, Ian , DALE, James , LAN, Jiong , LEVINE, Barry , COSTALES, Abran , LIU, Jie , PICK, Teresa , MENEZES, Daniel
IPC分类号： C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04 , A61K31/437 , A61K31/5025 , A61K31/428 , A61P35/00
CPC分类号： C07D487/04 , C07D417/04 , C07D417/14 , C07D471/04
摘要： Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases.
摘要翻译：磷脂酰肌醇（PI）3激酶抑制剂化合物，其药学上可接受的盐和前药; 单独或与至少一种另外的治疗剂组合的新化合物与药学上可接受的载体的组合物; 以及单独或与至少一种另外的治疗剂联合使用的新化合物在预防或治疗以生长因子，蛋白丝氨酸/苏氨酸激酶，磷脂激酶，G蛋白偶联的异常活性为特征的增殖性疾病中的用途受体和磷酸酶。

5. 发明申请

WO2006072091A2 LINEAR MOVING CAPACITIVE SENSOR TWIN COLUMN ELECTRONIC HEIGHT GAUGE 审中-公开
标题翻译：线性移动电容传感器双列电子高度计
公开(公告)号：WO2006072091A2
公开(公告)日：2006-07-06
申请号：PCT/US2005/047651
申请日：2005-12-20
申请人： ZHANG, Yanchen
发明人： ZHANG, Yanchen
CPC分类号： G01B7/082
摘要： The present invention is an electronic height gauge utilizing new technology and includes a first column (Column 1) and a second column (Column 2), a display unit with a cover, a measuring scriber, a fixed capacitance sensor and a linear moving capacitance sensor. The fixed capacitance sensor is located on a flat surface on Column 1, flat surface having a length equivalent to the length of Column 1. The linear moving capacitance sensor is located inside the display unit cover positioned to face the fixed capacitance sensor. The fixed capacitive sensor and linear moving capacitive sensors are facing toward each other only, and do not make direct physical contact with the fixed capacitor sensor when the height gauge is operating in upward and downward movements. The fixed and moving capacitive sensors are instead making only electrical contact with each other when the height gauge is making upward and downward movements. This linear direct data noncontact sensor transfer system results in high accuracy of measurements, which also ensures the repeatability of accurate measurements. Also, since the fixed capacitance sensor and the linear moving capacitance sensor have no physical contact with each other, there is no wear and tear damage on either component part, thereby leading to a longer life of use with stability in accurate measurements and repeatability. Because the measuring system is comparatively simple, and easy to assemble and service and maintain compared to the existing rotary capacitive sensor electronic height gauges that exist on the market, the overall cost of production and maintenance is minimized. On the second column (Column 2), a simple rack and gear system is added. These gears of column 2 are connected to a hand wheel located on the rear of the display unit. The handwheel is used for making upward and downward vertical movements. This rack and gear system of column 2 of the present invention is only used to aid the same in making upward and downward movements, and does not affect the measuring accuracy of the height gauge, as it did in the height gauges that have existed on the market.
摘要翻译：本发明是一种利用新技术的电子高度计，包括第一列（列1）和第二列（列2），具有盖的显示单元，测量划线器，固定电容传感器和线性移动电容传感器。固定电容传感器位于列1上的平坦表面上，平坦表面的长度等于列1的长度。线性移动电容传感器位于显示单元盖内，定位为面对固定电容传感器。固定电容传感器和线性移动电容式传感器仅面向彼此，并且当高度计工作在上下运动时，不会与固定电容传感器直接物理接触。固定和移动的电容式传感器在高度计正在向上和向下移动时相反地仅形成彼此的电接触。这种线性直接数据非接触传感器传输系统导致测量的高精度，这也确保了精确测量的重复性。此外，由于固定电容传感器和线性移动电容传感器彼此没有物理接触，因此在任何一个部件上都不会产生磨损和损伤，因此在精确测量和重复性方面具有更长的使用寿命。由于测量系统比现有的旋转电容式传感器电子式高度计相对简单，易于组装和维护保养，因此生产和维护的整体成本最小化。在第二列（第2列）中，添加了一个简单的齿条和齿轮系统。列2的这些齿轮连接到位于显示单元后部的手轮。手轮用于向上和向下垂直运动。本发明的列2的该齿条和齿轮系仅用于上下运动，不影响高度计的测量精度，如同在市场。

6. 发明申请

WO2011060199A1 BORON-CONTAINING SMALL MOLECULES 审中-公开
标题翻译：含硼的小分子
公开(公告)号：WO2011060199A1
公开(公告)日：2011-05-19
申请号：PCT/US2010/056423
申请日：2010-11-11
申请人： ANACOR PHARMACEUTICALS, INC. , HERNANDEZ, Vincent, S. , LI, Xianfeng , ZHANG, Suoming , AKAMA, Tsutomu , ZHANG, Yanchen , LIU, Yang , PLATTNER, Jacob, J. , ALLEY, Michael Kevin, Richard , ZHOU, Yasheen , NEIMAN, James, A.
发明人： HERNANDEZ, Vincent, S. , LI, Xianfeng , ZHANG, Suoming , AKAMA, Tsutomu , ZHANG, Yanchen , LIU, Yang , PLATTNER, Jacob, J. , ALLEY, Michael Kevin, Richard , ZHOU, Yasheen , NEIMAN, James, A.
IPC分类号： C07F5/02 , A61K31/69 , A61P31/04
CPC分类号： C07F5/025
摘要： This invention relates to 6-substituted benzoxaborole compounds of the following formulae and their use for treating bacterial infections.
摘要翻译：本发明涉及下式的6-取代苯并恶唑化合物及其用于治疗细菌感染的用途。

8. 发明申请

WO2011060196A1 BORON-CONTAINING SMALL MOLECULES 审中-公开
标题翻译：含硼的小分子
公开(公告)号：WO2011060196A1
公开(公告)日：2011-05-19
申请号：PCT/US2010/056420
申请日：2010-11-11
申请人： ANACOR PHARMACEUTICALS, INC. , HERNANDEZ, Vincent, S. , LI, Xianfeng , ZHANG, Suoming , AKAMA, Tsutomu , ZHANG, Yanchen , LIU, Yang , PLATTNER, Jacob, J. , ALLEY, Michael, Kevin Richard , ZHOU, Yasheen , NEIMAN, James, A.
发明人： HERNANDEZ, Vincent, S. , LI, Xianfeng , ZHANG, Suoming , AKAMA, Tsutomu , ZHANG, Yanchen , LIU, Yang , PLATTNER, Jacob, J. , ALLEY, Michael, Kevin Richard , ZHOU, Yasheen , NEIMAN, James, A.
IPC分类号： C07F5/02 , A61K31/69 , A61K31/04
CPC分类号： C07F5/025
摘要： This invention relates to 6-substituted benzoxaborole compounds of the following formula and their use for treating bacterial infections.
摘要翻译：本发明涉及下式的6-取代苯并恶唑化合物及其用于治疗细菌感染的用途。

9. 发明申请

WO2008086188A3 THIOPHENE CARBOXAMIDES AS FACTOR XA INHIBITORS 审中-公开
标题翻译： THIOPHENE CARBOXAMIDES作为因子XA抑制剂
公开(公告)号：WO2008086188A3
公开(公告)日：2008-10-09
申请号：PCT/US2008050244
申请日：2008-01-04
申请人： MILLENNIUM PHARM INC , ZHU BING-YAN , BAUER SHAWN M , JIA ZHAOZHONG J , SONG YONGHONG , PROBST GARY D , ZHANG YANCHEN , SCARBOROUGH CARROLL EXECUTRIX FOR SCARBOROUGH ROBERT M
发明人： ZHU BING-YAN , BAUER SHAWN M , JIA ZHAOZHONG J , SONG YONGHONG , PROBST GARY D , ZHANG YANCHEN , SCARBOROUGH CARROLL EXECUTRIX
IPC分类号： C07D409/12 , A61K31/4155 , A61K31/4178 , A61K31/4192 , A61K31/421 , A61P9/00 , C07D409/14 , C07D413/14
CPC分类号： C07D409/14 , C07D333/38 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The present invention is directed to compounds represented by Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
摘要翻译：本发明涉及由式（I）表示的化合物或其药学上可接受的盐，酯或前药，其是因子Xa的抑制剂。本发明还涉及用于制备这种化合物的中间体，含有这些化合物的药物组合物，预防或治疗多种不想要的血栓形成特征的病症的方法以及抑制血液样品凝固的方法。

10. 发明申请

WO2008098058A1 PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE 审中-公开
标题翻译： PI 3激酶抑制剂及其使用方法
公开(公告)号：WO2008098058A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/053190
申请日：2008-02-06
申请人： NOVARTIS VACCINES AND DIAGNOSTICS, INC. , PECCHI, Sabina , NI, Zhi-jie , BURGER, Matthew , WAGMAN, Allan , ATALLAH, Gordana , BARTULIS, Sarah , NG, Simon , PFISTER, Keith, B. , SMITH, Aaron , ZHANG, Yanchen , MERRITT, Hanne , VOLIVA, Charles
发明人： PECCHI, Sabina , NI, Zhi-jie , BURGER, Matthew , WAGMAN, Allan , ATALLAH, Gordana , BARTULIS, Sarah , NG, Simon , PFISTER, Keith, B. , SMITH, Aaron , ZHANG, Yanchen , MERRITT, Hanne , VOLIVA, Charles
IPC分类号： C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , A61K31/5377 , A61P35/00
CPC分类号： C07D401/14 , C07D401/04 , C07D405/14 , C07D413/14
摘要： Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases, including proliferative diseases, inflammatory and obstructive airways diseases, allergic conditions, auutoimmune and cardiovascular diseases.
摘要翻译：磷脂酰肌醇（PI）3-激酶抑制剂化合物，其药学上可接受的盐和前药; 单独或与至少一种另外的治疗剂组合的新化合物与药学上可接受的载体的组合物; 以及单独或与至少一种另外的治疗剂组合的新化合物在预防或治疗特征在于生长因子异常活性，蛋白质丝氨酸/苏氨酸激酶和磷脂激酶（包括增殖性疾病）的疾病中的用途，炎性和阻塞性气道疾病，过敏性疾病，自身免疫性疾病和心血管疾病。

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