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1. 发明申请

WO2012103468A3 RADIATION THERAPY KNOWLEDGE EXCHANGE 审中-公开
标题翻译：辐射治疗知识交流
公开(公告)号：WO2012103468A3
公开(公告)日：2012-11-15
申请号：PCT/US2012022957
申请日：2012-01-27
申请人： VARIAN MED SYS INC , LANG BURTON , ZANKOWSKI COREY , BAGHAIE RAMIN
发明人： LANG BURTON , ZANKOWSKI COREY , BAGHAIE RAMIN
IPC分类号： G06Q50/24
CPC分类号： G06Q50/22 , G06Q10/10 , G16H50/70 , G16H80/00
摘要： A method for implementing a radiation therapy knowledge exchange starts with searching a database of cases studies and selecting a case study. The selected case study is downloaded. The downloaded case study is applied to a medical case, wherein the downloaded case is applied using deformable image registration to deform reference images of the downloaded case to medical images of the medical case. After application of the downloaded case study, the medical case is uploaded to the network, wherein uploading the medical case allows at least the submitting clinician to download, review, and edit at least a portion of the medical case to create a reviewed medical case. Finally, the reviewed medical case is downloaded and applied to the medical case to create a final medical case.
摘要翻译：实施放射治疗知识交换的方法开始于搜索案例研究数据库并选择案例研究。所选的案例研究被下载。下载的案例研究应用于医疗案例，其中下载的案例通过使用可变形的图像配准来应用，以将下载的案例的参考图像变形为医疗案例的医疗图像。在应用下载的案例研究之后，医学案例被上传到网络，其中上传医学案例允许至少提交临床医师下载，查看和编辑至少一部分医疗案例以创建经审查的医疗案例。最后，下载审查的医疗案例并将其应用于医疗案件，以创建最终的医疗案例。

2. 发明申请

WO2012129328A2 KNOWLEDGE-BASED AUTOMATIC IMAGE SEGMENTATION 审中-公开
标题翻译：基于知识的自动图像分割
公开(公告)号：WO2012129328A2
公开(公告)日：2012-09-27
申请号：PCT/US2012/029980
申请日：2012-03-21
申请人： VARIAN MEDICAL SYSTEMS, INC. , ZANKOWSKI, Corey
发明人： ZANKOWSKI, Corey
IPC分类号： G06F17/00 , G06T1/00
CPC分类号： G06T7/149 , G06T7/33 , G06T2207/20128 , G06T2207/30004
摘要： A method for medical image segmentation includes accessing and updating a knowledge-base. First, a medical image is received and a sparse landmark signature is computed based on the medical image. Next, either a representative or a cohort average reference image set is selected. A portion of either representative reference image set or the cohort average reference image set is deformed to generate mappings to the medical image set. A segmentation for each structure of interest of the medical image set is determined. The knowledge-base is searched for representative matches to form a plurality of sub-volume base sets comprising a plurality of reference image set sub-volumes. A portion of the plurality of reference image set sub-volumes of the plurality of sub-volume base sets is deformed to generate mappings from the plurality of sub-volume base sets to corresponding structures of interest of the medical image set. A weighted-average segmentation for the plurality of structures of interest in the medical image set is calculated.
摘要翻译：用于医学图像分割的方法包括访问和更新知识库。首先，接收医学图像，并且基于医学图像计算稀疏地标签名。接下来，选择代表性或队列平均参考图像集合。代表参考图像集或队列平均参考图像集合的一部分变形以产生对医学图像集合的映射。确定医学图像集的感兴趣的每个结构的分割。搜索知识库以进行代表性匹配以形成包括多个参考图像集子卷的多个子卷基本集合。多个子体积基本集合中的多个参考图像集子体积的一部分被变形以产生从多个子体积基本集合到医学图像集的感兴趣的对应结构的映射。计算医疗图像集中感兴趣的多个结构的加权平均分割。

3. 发明申请

WO2012103468A2 RADIATION THERAPY KNOWLEDGE EXCHANGE 审中-公开
标题翻译：辐射治疗知识交流
公开(公告)号：WO2012103468A2
公开(公告)日：2012-08-02
申请号：PCT/US2012/022957
申请日：2012-01-27
申请人： VARIAN MEDICAL SYSTEMS, INC. , LANG, Burton , ZANKOWSKI, Corey , BAGHAIE, Ramin
发明人： LANG, Burton , ZANKOWSKI, Corey , BAGHAIE, Ramin
IPC分类号： G06Q50/24
CPC分类号： G06Q50/22 , G06F19/00 , G06Q10/10 , G16H50/70 , G16H80/00
摘要： A method for implementing a radiation therapy knowledge exchange starts with searching a database of cases studies and selecting a case study. The selected case study is downloaded. The downloaded case study is applied to a medical case, wherein the downloaded case is applied using deformable image registration to deform reference images of the downloaded case to medical images of the medical case. After application of the downloaded case study, the medical case is uploaded to the network, wherein uploading the medical case allows at least the submitting clinician to download, review, and edit at least a portion of the medical case to create a reviewed medical case. Finally, the reviewed medical case is downloaded and applied to the medical case to create a final medical case.
摘要翻译：实施放射治疗知识交流的方法首先从案例研究数据库和案例研究中选出。下载选定的案例研究。将下载的案例研究应用于医疗案例，其中使用可变形图像注册来应用下载的案例，以将下载的病例的参考图像变形为医疗病例的医学图像。在应用下载的案例研究之后，医疗案例被上传到网络，其中上传医疗案例允许至少提交临床医生下载，审查和编辑医疗案例的至少一部分以创建经审查的医疗案例。最后，经检查的医疗案例被下载并应用于医疗案件，以创建最终的医疗案例。

4. 发明申请

WO2010047923A2 METHODS AND SYSTEMS FOR TREATING BREAST CANCER USING EXTERNAL BEAM RADIATION 审中-公开
标题翻译：使用外部束辐射治疗乳腺癌的方法和系统
公开(公告)号：WO2010047923A2
公开(公告)日：2010-04-29
申请号：PCT/US2009/058662
申请日：2009-09-28
申请人： VARIAN MEDICAL SYSTEMS, INC. , STAR-LACK, Josh , HUMBER, David , KNOTT, Karla , ZANKOWSKI, Corey , GREEN, Michael C. , VIRSHUP, Gary , CLAYTON, James , SVATOS, Michelle Marie
发明人： STAR-LACK, Josh , HUMBER, David , KNOTT, Karla , ZANKOWSKI, Corey , GREEN, Michael C. , VIRSHUP, Gary , CLAYTON, James , SVATOS, Michelle Marie
IPC分类号： A61N5/10 , A61B6/00 , A61N5/01
CPC分类号： A61N5/1042 , A61B6/04 , A61B6/0435 , A61B6/4071 , A61B6/4458 , A61B6/4488 , A61B6/502 , A61B6/583
摘要： A radiation apparatus includes a radiation source movable in translational and/or rotational degrees of freedom, and a structure adapted to support a body. The structure is provided with an opening to allow a portion of the body passing through to be exposed to at least a portion of the therapeutic radiation while in use.
摘要翻译：辐射装置包括可平移和/或旋转自由度移动的辐射源，以及适于支撑身体的结构。该结构设置有开口，以允许身体通过的一部分在使用中暴露于治疗辐射的至少一部分。

5. 发明申请

WO2013049845A3 SEMANTIC RADIATION TREATMENT PLAN OPTIMIZATION GUIDANCE 审中-公开
标题翻译：语义辐射治疗计划优化指导
公开(公告)号：WO2013049845A3
公开(公告)日：2013-05-23
申请号：PCT/US2012058355
申请日：2012-10-01
申请人： VARIAN MEDICAL SYSTEMS INT AG , TOIMELA LASSE , NORD JANNE , ZANKOWSKI COREY
发明人： TOIMELA LASSE , NORD JANNE , ZANKOWSKI COREY
IPC分类号： A61N5/00 , G06Q50/22
CPC分类号： A61N5/1031 , A61N2005/1041
摘要： A method for radiation therapy treatment plan optimization, comprising generating a first radiation therapy treatment plan for a patient using a selected treatment type from a database and optimizing the first radiation therapy treatment plan. A selection of metrics from the first radiation therapy treatment plan are identified and compared to metrics from aggregated prior patient records selected from the database. At least one parameter is identified that affects the ability of the first radiation therapy treatment plan to meet an identified metric. The at least one parameter is defined with a single, clinically meaningful, human understandable language statement. The at least one parameter for the identified metric is compared to at least one parameter for a competing metric and at least one alternative treatment step for the treatment plan is determined that will change the identified at least one parameter to improve the identified metric. The at least one alternative treatment step is expressed in clinically meaningful, human understandable language.
摘要翻译：一种用于放射疗法治疗计划优化的方法，包括使用来自数据库的选择的治疗类型为患者生成第一放射疗法治疗计划并优化第一放射疗法治疗计划。识别来自第一放射疗法治疗计划的一系列指标并将其与来自数据库中选择的聚集的先前患者记录的指标进行比较。识别至少一个参数，其影响第一放射疗法治疗计划满足所识别的度量的能力。至少一个参数用单一的临床上有意义的，人类可理解的语言陈述来定义。将针对所识别的度量的所述至少一个参数与针对竞争性度量的至少一个参数进行比较，并且确定将改变所识别的至少一个参数以改善所识别的度量的治疗计划的至少一个替代治疗步骤。至少一个替代治疗步骤以临床上有意义的，人类可理解的语言表达。

6. 发明申请

WO2012129328A3 KNOWLEDGE-BASED AUTOMATIC IMAGE SEGMENTATION 审中-公开
标题翻译：基于知识的自动图像分割
公开(公告)号：WO2012129328A3
公开(公告)日：2012-12-27
申请号：PCT/US2012029980
申请日：2012-03-21
申请人： VARIAN MED SYS INC , ZANKOWSKI COREY
发明人： ZANKOWSKI COREY
IPC分类号： G06F17/00 , G06T1/00
CPC分类号： G06T7/149 , G06T7/33 , G06T2207/20128 , G06T2207/30004
摘要： A method for medical image segmentation includes accessing and updating a knowledge-base. First, a medical image is received and a sparse landmark signature is computed based on the medical image. Next, either a representative or a cohort average reference image set is selected. A portion of either representative reference image set or the cohort average reference image set is deformed to generate mappings to the medical image set. A segmentation for each structure of interest of the medical image set is determined. The knowledge-base is searched for representative matches to form a plurality of sub-volume base sets comprising a plurality of reference image set sub-volumes. A portion of the plurality of reference image set sub-volumes of the plurality of sub-volume base sets is deformed to generate mappings from the plurality of sub-volume base sets to corresponding structures of interest of the medical image set. A weighted-average segmentation for the plurality of structures of interest in the medical image set is calculated.
摘要翻译：一种用于医学图像分割的方法包括访问和更新知识库。首先，接收医学图像，并基于医学图像计算稀疏的标志符号。接下来，选择代表或群组平均参考图像组。代表参考图像组或部分平均参考图像组的一部分被变形以生成到医学图像组的映射。确定医学图像组的每个感兴趣结构的分割。搜索知识库中的代表性匹配以形成包括多个参考图像集子卷的多个子卷基本集合。多个子体积基本集合的多个参考图像集合子体积中的一部分被变形以生成从多个子体积基本集合到医学图像集合的相应的感兴趣结构的映射。计算医学图像集合中的多个感兴趣结构的加权平均分割。

7. 发明申请

WO2012015667A2 KNOWLEDGE-BASED AUTOMATIC IMAGE SEGMENTATION 审中-公开
标题翻译：基于知识的自动图像分割
公开(公告)号：WO2012015667A2
公开(公告)日：2012-02-02
申请号：PCT/US2011/044871
申请日：2011-07-21
申请人： VARIAN MEDICAL SYSTEMS, INC. , ZANKOWSKI, Corey
发明人： ZANKOWSKI, Corey
IPC分类号： A61B6/00 , A61B5/055 , G06F19/00 , G06T1/00
CPC分类号： G06T7/0087 , G06T7/11 , G06T7/143 , G06T2207/20128 , G06T2207/30004 , G06T2207/30061 , G06T2207/30081 , G06T2207/30096 , G06T2207/30204
摘要： A method for medical image segmentation. The method includes accessing and updating a knowledge-base in accordance with embodiments of the present invention. The techniques include: receiving a medical image and computing a sparse landmark signature based on the medical image content. Next, a knowledge-base is searched for representative matches to form a base set, wherein the base set comprises a plurality of reference image sets. A portion of the plurality of reference image sets of the base set is deformed to generate mappings from the base set to the medical image set. Finally a weighted average segmentation for each structure of interest of the medical image set is determined.
摘要翻译：一种医学图像分割方法。该方法包括根据本发明的实施例访问和更新知识库。所述技术包括：基于医学图像内容接收医学图像和计算稀疏地标签名。接下来，搜索知识库以进行代表性匹配以形成基本集合，其中基本集合包括多个参考图像集合。基本组的多个参考图像组的一部分被变形以产生从基本集合到医学图像集合的映射。最后，确定医学图像集的感兴趣结构的加权平均分割。

8. 发明申请

WO2013049845A2 SEMANTIC RADIATION TREATMENT PLAN OPTIMIZATION GUIDANCE 审中-公开
标题翻译：语义辐射治疗计划优化指导
公开(公告)号：WO2013049845A2
公开(公告)日：2013-04-04
申请号：PCT/US2012/058355
申请日：2012-10-01
申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , TOIMELA, Lasse , NORD, Janne , ZANKOWSKI, Corey
发明人： TOIMELA, Lasse , NORD, Janne , ZANKOWSKI, Corey
CPC分类号： A61N5/1031 , A61N2005/1041
摘要： A method for radiation therapy treatment plan optimization, comprising generating a first radiation therapy treatment plan for a patient using a selected treatment type from a database and optimizing the first radiation therapy treatment plan. A selection of metrics from the first radiation therapy treatment plan are identified and compared to metrics from aggregated prior patient records selected from the database. At least one parameter is identified that affects the ability of the first radiation therapy treatment plan to meet an identified metric. The at least one parameter is defined with a single, clinically meaningful, human understandable language statement. The at least one parameter for the identified metric is compared to at least one parameter for a competing metric and at least one alternative treatment step for the treatment plan is determined that will change the identified at least one parameter to improve the identified metric. The at least one alternative treatment step is expressed in clinically meaningful, human understandable language.
摘要翻译：一种用于放射治疗治疗计划优化的方法，包括利用来自数据库的选定治疗类型为患者生成第一放射疗法治疗计划并优化第一放射疗法治疗计划。识别来自第一放射治疗治疗计划的指标的选择，并将其与从数据库中选择的汇总的先前患者记录进行比较。至少有一个参数会影响第一个放射疗法治疗计划达到识别度量的能力。至少一个参数是用单一的，临床有意义的，人类可理解的语言语句定义的。将所识别的度量的至少一个参数与竞争度量的至少一个参数进行比较，并且确定用于治疗计划的至少一个替代治疗步骤，其将改变所识别的至少一个参数以改善所识别的度量。至少一个替代治疗步骤用临床上有意义的人类可理解的语言表达。

9. 发明申请

WO2012015667A3 KNOWLEDGE-BASED AUTOMATIC IMAGE SEGMENTATION 审中-公开
标题翻译：基于知识的自动图像分割
公开(公告)号：WO2012015667A3
公开(公告)日：2012-05-24
申请号：PCT/US2011044871
申请日：2011-07-21
申请人： VARIAN MED SYS INC , ZANKOWSKI COREY
发明人： ZANKOWSKI COREY
IPC分类号： A61B6/00 , A61B5/055 , G06F19/00 , G06T1/00
CPC分类号： G06T7/0087 , G06T7/11 , G06T7/143 , G06T2207/20128 , G06T2207/30004 , G06T2207/30061 , G06T2207/30081 , G06T2207/30096 , G06T2207/30204
摘要： A method for medical image segmentation. The method includes accessing and updating a knowledge-base in accordance with embodiments of the present invention. The techniques include: receiving a medical image and computing a sparse landmark signature based on the medical image content. Next, a knowledge-base is searched for representative matches to form a base set, wherein the base set comprises a plurality of reference image sets. A portion of the plurality of reference image sets of the base set is deformed to generate mappings from the base set to the medical image set. Finally a weighted average segmentation for each structure of interest of the medical image set is determined.
摘要翻译：一种医学图像分割方法。该方法包括根据本发明的实施例访问和更新知识库。这些技术包括：接收医学图像并基于医学图像内容计算稀疏的标志性签名。接下来，在知识库中搜索代表性匹配以形成基本集合，其中基本集合包括多个参考图像集合。基本集合的多个参考图像集合中的一部分被变形以生成从基本集合到医学图像集合的映射。最后，确定医学图像集的每个感兴趣结构的加权平均分割。

10. 发明申请

WO2010047923A3 METHODS AND SYSTEMS FOR TREATING BREAST CANCER USING EXTERNAL BEAM RADIATION 审中-公开
标题翻译：使用外部束辐射治疗乳腺癌的方法和系统
公开(公告)号：WO2010047923A3
公开(公告)日：2010-07-29
申请号：PCT/US2009058662
申请日：2009-09-28
申请人： VARIAN MED SYS INC , STAR-LACK JOSH , HUMBER DAVID , KNOTT KARLA , ZANKOWSKI COREY , GREEN MICHAEL C , VIRSHUP GARY , CLAYTON JAMES , SVATOS MICHELLE MARIE
发明人： STAR-LACK JOSH , HUMBER DAVID , KNOTT KARLA , ZANKOWSKI COREY , GREEN MICHAEL C , VIRSHUP GARY , CLAYTON JAMES , SVATOS MICHELLE MARIE
IPC分类号： A61N5/10 , A61B6/00 , A61N5/01
CPC分类号： A61N5/1042 , A61B6/04 , A61B6/0435 , A61B6/4071 , A61B6/4458 , A61B6/4488 , A61B6/502 , A61B6/583
摘要： A radiation apparatus includes a radiation source movable in translational and/or rotational degrees of freedom, and a structure adapted to support a body. The structure is provided with an opening to allow a portion of the body passing through to be exposed to at least a portion of the therapeutic radiation while in use.
摘要翻译：辐射装置包括可在平移和/或旋转自由度上移动的辐射源以及适于支撑身体的结构。该结构设置有开口以允许身体的一部分穿过以在使用时暴露于至少一部分治疗辐射。

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