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1. 发明授权

US08378119B2 Method for producing asymmetric tetrasubstituted carbon atom-containing compound 失效
标题翻译：不对称四取代碳原子化合物的制备方法
公开(公告)号：US08378119B2
公开(公告)日：2013-02-19
申请号：US13407250
申请日：2012-02-28
申请人： Yuichiro Tani , Yutaka Kitagawa , Makoto Muto , Toshiaki Jyono
发明人： Yuichiro Tani , Yutaka Kitagawa , Makoto Muto , Toshiaki Jyono
IPC分类号： C07D209/34
CPC分类号： C07C255/31 , C07B53/00 , C07C271/22 , C07D209/54 , C07D401/04
摘要： The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent.
摘要翻译：本发明提供一种生产螺环氨基吡咯烷酮衍生物的工业方法，其是用于生产喹诺酮抗菌剂的中间体。

2. 发明授权

US08376076B2 Device storage apparatus for railway vehicle 有权
标题翻译：铁路车辆设备存储装置
公开(公告)号：US08376076B2
公开(公告)日：2013-02-19
申请号：US13025716
申请日：2011-02-11
申请人： Shin Kataoka , Kunihiko Takagi , Yutaka Kitagawa
发明人： Shin Kataoka , Kunihiko Takagi , Yutaka Kitagawa
IPC分类号： B60R16/04
CPC分类号： B61C17/00
摘要： An apparatus for storing a device for a railway vehicle, comprises a storage case having an opening at a front side, a tray accommodated into the storage case, the tray being movable forward and backward with the device mounted thereon, a lever disposed at an upper side of the tray to extend along a forward and backward direction, the lever being vertically pivotable around a pivot forward relative to a center of the tray in the forward and backward direction, an operation member coupled to a front end portion of the lever and disposed at a front side of the tray, an engagement portion provided at a rear end portion of the lever and protruding downward outside the tray, and a recess provided in the storage case, the engagement portion being fitted into the recess from above.
摘要翻译：一种用于存储用于铁路车辆的装置的装置，包括：前侧具有开口的存放箱，容纳在所述收纳箱内的托盘，所述托盘可安装在所述装置上的前后方向移动，所述托盘沿着前后方向延伸，所述杠杆可相对于所述托盘的向前和向后方向的中心而绕枢轴向上竖直地枢转;联接到所述杠杆的前端部分的操作构件，在所述托盘的前侧，设置在所述杆的后端部并且向下突出到所述托盘的下方的接合部以及设置在所述收纳壳体中的凹部，所述接合部从上方嵌入所述凹部。

3. 发明授权

US08348204B2 Cable guide unit water-proof device for railway vehicle 失效
标题翻译：铁路车辆导轨单元防水装置
公开(公告)号：US08348204B2
公开(公告)日：2013-01-08
申请号：US13030825
申请日：2011-02-18
申请人： Shin Kataoka , Kunihiko Takagi , Yutaka Kitagawa , Kazuya Morita
发明人： Shin Kataoka , Kunihiko Takagi , Yutaka Kitagawa , Kazuya Morita
IPC分类号： F16L3/22 , H01B7/00
CPC分类号： H02G3/088 , B61D49/00
摘要： A waterproof cable guide device for a railway vehicle comprises an elastic member having a plurality of through-holes penetrating in a forward and backward direction and screw insertion holes penetrating in the forward and backward direction, the plurality of electric cables being inserted into the plurality of holes, respectively, the elastic member being divided in positions of the through-holes or having slits extending from an outer peripheral surface of the elastic member to the through-holes, respectively; a press casing surrounding a front surface and an outer peripheral surface of the elastic member so as not to cover the through-holes and provided with screw insertion holes communicating with the screw insertion holes of the elastic member; and screws inserted into the screw insertion holes, in a direction from forward, and tightened with respect to the cable guide; the screws being inserted into the screw insertion holes in the direction from forward and tightened with respect to the cable guide in a state where the electric cables are inserted into the through-holes, respectively, to cause the elastic member to be compressed by the press casing to closely contact peripheral surfaces of the electric cables.
摘要翻译：一种用于铁路车辆的防水电缆引导装置，包括具有沿前后方向贯穿的多个通孔的弹性构件和沿前后方向贯穿的螺钉插入孔，多个电缆插入到多个所述弹性构件分别被分割成所述通孔的位置或具有从所述弹性构件的外周面延伸到所述通孔的狭缝; 围绕所述弹性构件的前表面和外周面的按压套，以便不覆盖所述通孔，并且设置有与所述弹性构件的所述螺钉插入孔连通的螺钉插入孔; 以及螺钉插入螺钉插入孔中的方向从前方方向相对于缆索引导件紧固; 在将电缆分别插入通孔的状态下，分别将螺钉沿相对于电缆引导件的向前和向前的方向插入螺钉插入孔中，以使弹性构件被压机压缩壳体紧密接触电缆的外围表面。

4. 发明申请

US20120071685A1 METHOD FOR PRODUCING BICYCLIC gamma-AMINO ACID DERIVATIVE 有权
标题翻译：制备双相γ-氨基酸衍生物的方法
公开(公告)号：US20120071685A1
公开(公告)日：2012-03-22
申请号：US13241933
申请日：2011-09-23
申请人： Yutaka Kitagawa , Makoto Imai
发明人： Yutaka Kitagawa , Makoto Imai
IPC分类号： C07C67/333 , C07C51/353
CPC分类号： C07B57/00 , A61K31/195 , A61K31/215 , C07B2200/07 , C07C227/34 , C07C2602/20 , Y02P20/55 , C07C229/32
摘要： Methods for producing compounds having activity as an α2δ ligand are provided.
摘要翻译：提供了具有作为α2δ配体活性的化合物的方法。

5. 发明授权

US08138352B2 Method for producing asymmetric tetrasubstituted carbon atom-containing compound 失效
标题翻译：不对称四取代碳原子化合物的制备方法
公开(公告)号：US08138352B2
公开(公告)日：2012-03-20
申请号：US13032135
申请日：2011-02-22
申请人： Yuichiro Tani , Yutaka Kitagawa , Makoto Muto , Toshiaki Jyono
发明人： Yuichiro Tani , Yutaka Kitagawa , Makoto Muto , Toshiaki Jyono
IPC分类号： C07D209/54
CPC分类号： C07C255/31 , C07B53/00 , C07C271/22 , C07D209/54 , C07D401/04
摘要： The invention provides an industrial method for producing a spiroaminopyrrolidone derivative, which is an intermediate for producing a quinolone antibacterial agent. Specifically, the invention provides a method for producing a compound of formula (2): wherein n is an integer of 2 to 5; R1 is a (substituted) alkyl group or a (substituted) aryl group; and R2 represents a (substituted) alkoxycarbonyl group, a (substituted) aralkyloxycarbonyl group, a (substituted) aliphatic acyl group, or a (substituted) aromatic acyl group).
摘要翻译：本发明提供一种生产螺环氨基吡咯烷酮衍生物的工业方法，其是用于生产喹诺酮抗菌剂的中间体。具体地说，本发明提供了制备式（2）化合物的方法：其中n为2至5的整数; R1是（取代的）烷基或（取代的）芳基; R2代表（取代的）烷氧基羰基，（取代的）芳烷氧基羰基，（取代的）脂族酰基或（取代的）芳族酰基）。

6. 发明申请

US20110253846A1 CABLE GUIDE UNIT WATER-PROOF DEVICE FOR RAILWAY VEHICLE 有权
标题翻译：用于铁路车辆的电缆导轨防水装置
公开(公告)号：US20110253846A1
公开(公告)日：2011-10-20
申请号：US13030520
申请日：2011-02-18
申请人： Shin KATAOKA , Kunihiko TAKAGI , Yutaka KITAGAWA , Kazuya MORITA
发明人： Shin KATAOKA , Kunihiko TAKAGI , Yutaka KITAGAWA , Kazuya MORITA
IPC分类号： F16L3/10
CPC分类号： H02G3/088 , B61D49/00
摘要： A waterproof cable guide device for a railway vehicle, comprises an elastic member of a substantially rectangular prism shape, which has a plurality of through-holes into which the plurality of electric cables are inserted, respectively, the plurality of through-holes penetrating the elastic member in a forward and backward direction, the elastic member being divided in positions of the through-holes or having slits extending from an outer peripheral surface of the elastic member to the through-holes, respectively; a plurality of divided press casings into which a casing is divided in a vertical direction and in a lateral direction, the plurality of divided press casings surrounding a front surface, right and left side surfaces and upper and lower surfaces of the elastic member so as not to cover the through-holes; a first fastener member which tightens the plurality of divided press casings toward the cable guide; a second fastener member which tightens the plurality of divided press casings closer to each other in the vertical direction; and a third fastener member which tightens the plurality of divided press casings closer to each other in the lateral direction.
摘要翻译：一种用于铁路车辆的防水电缆引导装置，包括大致矩形棱柱形状的弹性构件，该弹性构件具有分别插入多根电缆的多个通孔，所述多个贯通弹性体的通孔所述弹性构件被分割成所述通孔的位置，或者具有从所述弹性构件的外周面延伸到所述通孔的狭缝; 多个分开的按压壳体，其中壳体沿垂直方向和横向被分割成多个，所述多个分隔的压力机壳围绕弹性构件的前表面，左右侧表面和上表面和下表面，以便不会覆盖通孔; 第一紧固件，其将多个分开的压力机壳朝着所述电缆引导件收紧; 第二紧固件，其在垂直方向上彼此靠近地紧固所述多个分隔的压力机壳; 以及第三紧固件，其将横向上彼此更靠近的多个分开的压力机壳紧固。

7. 发明申请

US20110173387A1 STORAGE SYSTEM HAVING FUNCTION OF PERFORMING FORMATTING OR SHREDDING 失效
标题翻译：具有执行格式或缩放功能的存储系统
公开(公告)号：US20110173387A1
公开(公告)日：2011-07-14
申请号：US12298263
申请日：2008-10-01
申请人： Yutaka Kitagawa , Akira Ooigawa
发明人： Yutaka Kitagawa , Akira Ooigawa
IPC分类号： G06F12/00 , G06F3/00
CPC分类号： G06F3/0635 , G06F3/0605 , G06F3/0622 , G06F3/0652 , G06F3/0683
摘要： It is desired to reduce the danger of leakage of data stored in a logical storage device. A storage system has a detection unit and a security processing unit. The detection unit detects a system change, during which it is not possible to perform I/O for a first logical storage device, among a plurality of logical storage devices in the storage system. And the security processing unit takes this type of system change as the opportunity for performing security processing, i.e. formatting or shredding, upon the first logical storage device.
摘要翻译：期望减少存储在逻辑存储设备中的数据泄露的危险。存储系统具有检测单元和安全处理单元。检测单元检测在存储系统中的多个逻辑存储设备之间不能对第一逻辑存储设备执行I / O的系统改变。并且安全处理单元将这种类型的系统改变作为在第一逻辑存储设备上执行安全处理（即，格式化或粉碎）的机会。

8. 发明申请

US20070117988A1 Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates 失效
标题翻译：用于制备光学活性环丙胺衍生物的中间体和用于生产中间体的方法
公开(公告)号：US20070117988A1
公开(公告)日：2007-05-24
申请号：US10582400
申请日：2004-09-30
申请人： Masao Fujita , Yutaka Kitagawa , Makoto Muto
发明人： Masao Fujita , Yutaka Kitagawa , Makoto Muto
IPC分类号： C07D207/04 , C07D207/46
CPC分类号： C07D207/20 , C07B2200/07 , C07D207/09 , C07D207/12 , C07D207/16 , Y02P20/55
摘要： The present invention provides intermediates needed for production of an optically active compound represented by formula (6), which enable the compound (6) to be readily synthesized in simple production steps without optical resolution, and also provides a process for producing the intermediates. A process for producing an optically active compound represented by formula (4): wherein R1 represents a protecting group for the amino group, or a salt thereof, characterized in that a reagent prepared from an titanium(IV) reagent and an alkylmetal compound is reacted with an optically active compound represented by formula (3): wherein R1 has the same meaning as defined above, if needed, in the presence of a Lewis acid.
摘要翻译：本发明提供制备由式（6）表示的光学活性化合物所需的中间体，其使得化合物（6）能够在没有光学拆分的情况下以简单的制备步骤容易地合成，并且还提供了制备中间体的方法。一种制备由式（4）表示的光学活性化合物的方法：其中R 1表示氨基的保护基或其盐，其特征在于由钛制备的试剂（IV ）试剂，烷基金属化合物与由式（3）表示的光学活性化合物反应：其中R 1具有如上所定义的含义，如果需要，在路易斯酸存在下。

9. 发明授权

US07126003B2 Method for producing 2-azetidinone derivative 有权
标题翻译： 2-氮杂环丁酮衍生物的制备方法
公开(公告)号：US07126003B2
公开(公告)日：2006-10-24
申请号：US10469918
申请日：2002-03-04
申请人： Kouji Sato , Tsutomu Yagi , Yutaka Kitagawa , Shigeru Ichikawa , Akihiro Imura
发明人： Kouji Sato , Tsutomu Yagi , Yutaka Kitagawa , Shigeru Ichikawa , Akihiro Imura
IPC分类号： C07D401/04 , C07D205/04
CPC分类号： C07D401/04 , C07D205/08 , C12P17/10 , C12P41/003
摘要： A process for producing a compound represented by the following formula (II) which comprises treating a compound represented by the following formula (I) (wherein R1, R2 and R3 represent each a specific substituent) with an enzyme capable of asymmetrically hydrolyzing an ester and the novel compound (II). The process of the present invention makes it possible to easily obtain an optically active 2-azetidinone derivative in a large amount at a low cost
摘要翻译：一种制备由下式（II）表示的化合物的方法，其包括将下式（I）表示的化合物（其中R 1，R 2，R 2和R 2）具有能够不对称地水解酯和新化合物（II）的酶代表每个特定取代基）。本发明的方法使得可以以低成本容易地获得大量光学活性的2-氮杂环丁酮衍生物

10. 发明申请

US20060135775A1 Intermediates and process for the production of optically active quinolonecarboxylic acid derivatives 失效
标题翻译：用于制备光学活性喹诺酮羧酸衍生物的中间体和方法
公开(公告)号：US20060135775A1
公开(公告)日：2006-06-22
申请号：US10559499
申请日：2004-06-04
申请人： Makoto Muto , Manabu Miura , Yutaka Kitagawa
发明人： Makoto Muto , Manabu Miura , Yutaka Kitagawa
IPC分类号： C07D215/36
CPC分类号： C07D215/56 , A01N43/42 , C07C51/00 , C07C65/21 , C07C225/16 , C07C255/43 , C07C2601/02 , C07D215/54
摘要： [Problem]Provision of a commercially advantageous method for producing an intermediate which is important for producing the antibacterial and which has a mother nucleus common to the antibacterial, and intermediates produced by such method. [Means to Solve the Problem] A method for producing a compound represented by formula (VI): which comprises the steps of treating a compound represented by formula (IV): with a base in the presence of a base to produce a compound represented by formula (V): and hydrolyzing this compound; a compound represented by formula (II): a compound represented by formula (Ia): a compound represented by formula (V): and a compound represented by formula (VI)
摘要翻译： [问题]提供一种商业上有利的生产中和体的方法，该方法对于生产抗菌剂是重要的，并且具有抗细菌共有的母核以及通过这种方法生产的中间体。解决问题的方法由式（VI）表示的化合物的制备方法：其包括在碱的存在下用碱处理由式（IV）表示的化合物的步骤，以制备由式式（Ⅴ）：水解该化合物; 由式（II）表示的化合物：由式（Ia）表示的化合物：由式（V）表示的化合物和由式（VI）表示的化合物

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