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    • 3. 发明授权
    • Small molecular compounds capable of accelerating proliferation of stem cells and use thereof
    • 能够促进干细胞增殖的小分子化合物及其用途
    • US08618145B2
    • 2013-12-31
    • US13320203
    • 2009-05-12
    • Mei HanYan FengYuanyuan Sun
    • Mei HanYan FengYuanyuan Sun
    • A61K31/4245C07D271/113
    • C07D271/07
    • The invention provides small molecule compounds capable of accelerating proliferation of stem cells and uses thereof. The compounds play an important role in the research of stem cell proliferation mechanism. The invention further relates to the uses of the compounds and relevant compounds thereof in the preparation of stem cell proliferation accelerators and the preparation of medicines accelerating stem cell proliferation. The invention also relates to the uses of the compounds in the preparation of medicines for the treatment of various diseases arising from functional cells loss or damage. The diseases arising from stem cell trauma comprise diseases related to the degeneration or damage of nervous system cells, blood system diseases, diseases related to the loss or damage of cardiovascular cells, skin burn and the like.
    • 本发明提供能够促进干细胞增殖的小分子化合物及其用途。 该化合物在干细胞增殖机制研究中起着重要作用。 本发明还涉及化合物及其相关化合物在制备干细胞增殖促进剂中的用途以及加速干细胞增殖的药物的制备。 本发明还涉及该化合物在制备用于治疗由功能性细胞损失或损伤引起的各种疾病的药物中的用途。 由干细胞创伤引起的疾病包括与神经系统细胞的退化或损伤相关的疾病,血液系统疾病,与心血管细胞的损失或损伤有关的疾病,皮肤灼伤等。