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    • 2. 发明申请
    • IMMUNODETECTION PROBE AND METHOD OF IMMUNODETECTION USING THE SAME
    • 免疫检测方法和使用该方法进行免疫检测
    • US20110136132A1
    • 2011-06-09
    • US12917706
    • 2010-11-02
    • FAN GANG TSENGYUAN TAI TSENG
    • FAN GANG TSENGYUAN TAI TSENG
    • G01N33/53C12M1/34
    • A61B5/14546A61B5/14528A61B5/1459A61B5/6848
    • An immunodetection probe comprises a needle structure having a compartment and configured to be inserted into an organic tissue, a dialysis membrane configured to isolate the compartment from the organic tissue, a detection device having a detection portion and a plurality of receptors, a first optical fiber coupled to the needle structure, and a pair of tubes connected to the compartment. The plurality of receptors are disposed on an end surface of the detection portion for conjugating a target antibody, wherein the detection portion is disposed in the compartment. The first optical fiber is configured to introduce light incident on photo-induced molecules adjacent to the end surface of the detection portion so as to cause a change in the pH level of the solution adjacent to the end surface of the detection portion. The pair of tubes is configured to transport the solution containing the photo-induced molecules into the compartment.
    • 免疫检测探针包括具有隔室并构造成插入有机组织的针结构,被配置为将隔室与有机组织隔离的透析膜,具有检测部分和多个受体的检测装置,第一光纤 连接到针结构,以及连接到隔室的一对管。 所述多个受体被设置在所述检测部分的端面上,用于与目标抗体共轭,其中所述检测部分设置在所述隔室中。 第一光纤被配置为引入入射到与感测部分的端表面相邻的光致分子上的光,以引起邻近检测部分的端面的溶液的pH值的变化。 这对管被配置为将含有光诱导分子的溶液输送到隔室中。
    • 3. 发明授权
    • Immunodetection probe and method of immunodetection using the same
    • 免疫检测探针和免疫检测方法
    • US08785136B2
    • 2014-07-22
    • US12917706
    • 2010-11-02
    • Fan Gang TsengYuan Tai Tseng
    • Fan Gang TsengYuan Tai Tseng
    • G01N33/53A61B5/00A61B5/145A61B5/1459
    • A61B5/14546A61B5/14528A61B5/1459A61B5/6848
    • An immunodetection probe comprises a needle structure having a compartment and configured to be inserted into an organic tissue, a dialysis membrane configured to isolate the compartment from the organic tissue, a detection device having a detection portion and a plurality of receptors, a first optical fiber coupled to the needle structure, and a pair of tubes connected to the compartment. The plurality of receptors are disposed on an end surface of the detection portion for conjugating target antibodies, wherein the detection portion is disposed in the compartment. The first optical fiber is configured to introduce light incident on photo-induced molecules adjacent to the end surface of the detection portion so as to cause a change in the pH level of the solution adjacent to the end surface of the detection portion. The pair of tubes is configured to transport the solution containing the photo-induced molecules into the compartment.
    • 免疫检测探针包括具有隔室并构造成插入有机组织的针结构,被配置为将隔室与有机组织隔离的透析膜,具有检测部分和多个受体的检测装置,第一光纤 连接到针结构,以及连接到隔室的一对管。 多个受体被设置在检测部分的端表面上,用于共轭靶抗体,其中检测部分设置在隔室中。 第一光纤被配置为引入入射到与感测部分的端表面相邻的光致分子上的光,以引起邻近检测部分的端面的溶液的pH值的变化。 这对管被配置为将含有光诱导分子的溶液输送到隔室中。