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1. 发明申请

US20110118632A1 CARDIAC ABLATION DEVICES 审中-公开
标题翻译：心脏消融装置
公开(公告)号：US20110118632A1
公开(公告)日：2011-05-19
申请号：US12946735
申请日：2010-11-15
申请人： Yegor Sinelnikov , Yong Zou , Reinhard Warnking , James Savage , Robert C. Pacheco , Jaime Merino , Patrick David Lopath , John Hotmer , Todd Fjield
发明人： Yegor Sinelnikov , Yong Zou , Reinhard Warnking , James Savage , Robert C. Pacheco , Jaime Merino , Patrick David Lopath , John Hotmer , Todd Fjield
IPC分类号： A61N7/00
CPC分类号： A61B17/22004 , A61B17/22012 , A61B17/2202 , A61B17/2251 , A61B2017/00243 , A61B2017/00991 , A61B2017/22027 , A61B2017/22054 , A61B2017/22061
摘要： A cardiac ablation device treats atrial fibrillation by directing and focusing ultrasonic waves into a ring-like ablation region (A). The device desirably is steerable and can be moved between a normal disposition, in which the ablation region lies parallel to the wall of the heart for ablating a loop-like lesion, and a canted disposition, in which the ring-like focal region is tilted relative to the wall of the heart, to ablate only a short, substantially linear lesion. The ablation device desirably includes a balloon reflector structure (18, 1310) and an ultrasonic emitter assembly (23, 1326), and can be steered and positioned without reference to engagement between the device and the pulmonary vein or ostium. A contrast medium (C) can be injected through the ablation device to facilitate imaging, so that the device can be positioned based on observation of the images.
摘要翻译：心脏消融装置通过将超声波引导并聚焦到环形消融区域（A）中来治疗房颤。该装置理想地是可操纵的，并且可以在其中消融区域平行于心脏壁平行以消除环状病变的正常设置和倾斜位置之间移动，其中环形聚焦区域倾斜相对于心脏壁，仅消融短暂的，基本上线性的损伤。消融装置理想地包括球囊反射器结构（18,1310）和超声波发射器组件（23,1326），并且可以被引导和定位，而不参考装置与肺静脉或口腔之间的接合。可以通过消融装置注入造影剂（C）以促进成像，使得可以基于对图像的观察来定位装置。

2. 发明申请

US20090228003A1 Tissue ablation device using radiofrequency and high intensity focused ultrasound 审中-公开
标题翻译：组织消融装置采用射频和高强度聚焦超声
公开(公告)号：US20090228003A1
公开(公告)日：2009-09-10
申请号：US12074559
申请日：2008-03-04
申请人： Yegor Sinelnikov
发明人： Yegor Sinelnikov
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0022 , A61B2018/00375 , A61M25/0105 , A61M25/1011 , A61M2025/0681 , A61M2025/1013 , A61N7/022
摘要： Apparatus and methods for ablating tissue such as cardiac tissue. The apparatus includes a probe carrying a first ablation element 11 which may include an ultrasonic transducer and a balloon structure which directs the ultrasonic energy, and an additional ablation element 17 located distal to the first ablation element. The mode of operation of the additional ablation element 17 may be different from that of the first ablation element 20. Both ablation elements may be positioned by positioning the probe. The first ablation element may be arranged to form a loop-like lesion, whereas the additional ablation element may be arranged to form a spot-like lesion.
摘要翻译：用于消融诸如心脏组织的组织的装置和方法。该装置包括携带第一消融元件11的探针，其可以包括超声波换能器和引导超声波能量的球囊结构，以及位于第一消融元件远侧的附加消融元件17。附加消融元件17的操作模式可以不同于第一消融元件20的操作模式。通过定位探针可以定位两个消融元件。第一消融元件可以被布置成形成环状损伤，而附加的消融元件可以被布置成形成点状病变。

3. 发明申请

US20080255449A1 Ablation Devices and Methods With Ultrasonic Imaging 审中-公开
标题翻译：消融装置和方法与超声成像
公开(公告)号：US20080255449A1
公开(公告)日：2008-10-16
申请号：US11665321
申请日：2005-10-14
申请人： Reinhard Warnking , Yegor Sinelnikov
发明人： Reinhard Warnking , Yegor Sinelnikov
IPC分类号： A61B18/04 , A61B8/00
CPC分类号： A61F7/02 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B17/2202 , A61B2017/00243 , A61B2017/22024 , A61B2017/22051 , A61B2017/22058 , A61B2017/22069 , A61B2090/3782
摘要： Ablation apparatus such as a catheter (10) carrying an ultrasonic ablation device (20) including an ablation transducer (42) and a balloon reflector structure (22, 24) for directing ultrasonic energy from the ablation transducer into a ring-like ablation region (A) is provided with an imaging ultrasonic transducer (86) mounted on an imaging probe (80) which may be inserted into or through a passageway (18, 65) extending through the catheter and into or through the ablation device to image the ablation region or neighboring regions. Alternatively, the imaging transducer (102, 202) may be mounted within the balloon reflector structure or distal to this structure.
摘要翻译：消融装置，例如携带包括消融换能器（42）的超声波消融装置（20）的导管（10）和用于将来自消融换能器的超声能量引导到环状消融区域中的气囊反射器结构（22,24） A）设置有安装在成像探针（80）上的成像超声换能器（86），该成像超声换能器可插入或穿过延伸穿过导管的通道（18,65）并进入或穿过消融装置以成像消融区域或邻近区域。或者，成像换能器（102,202）可以安装在气球反射器结构内或远离该结构。

4. 发明授权

US08690783B2 Ultrasonic transducer assembly 有权
标题翻译：超声波换能器组件
公开(公告)号：US08690783B2
公开(公告)日：2014-04-08
申请号：US13203771
申请日：2011-05-20
申请人： Yegor Sinelnikov
发明人： Yegor Sinelnikov
IPC分类号： A61B8/00
CPC分类号： A61B17/320068 , A61B8/12 , A61B8/4209 , A61B8/445 , A61B8/4488 , A61B8/4494 , G01N29/221 , G01N29/2437
摘要： An ultrasound transducer assembly includes an acoustic focusing lens and a therapy transducer mounted to a holder member so that the lens is movable relative to the transducer. The lens and the transducer are mounted to the holder member so that the lens is spaced a predetermined distance from the transducer element. A liquid layer having a thickness of the predetermined distance is provided between the lens and the transducer element. A solid backing member is disposed on a side of the transducer element opposite the lens. The backing member is spaced by an additional liquid layer of a predetermined thickness from the transducer element. The focusing depth of the lens-transducer assembly is controllable by transducer operating frequency.
摘要翻译：超声换能器组件包括声聚焦透镜和安装到保持器构件的治疗换能器，使得透镜相对于换能器可移动。透镜和传感器安装到保持器构件，使得透镜与换能器元件间隔预定距离。在透镜和换能器元件之间设置具有预定距离厚度的液体层。固体背衬构件设置在与透镜相对的换能器元件的一侧。背衬构件与来自换能器元件的预定厚度的附加液体层隔开。透镜组件的聚焦深度可由传感器工作频率控制。

5. 发明授权

US10123903B2 Ablation devices and methods with ultrasonic imaging 有权
公开(公告)号：US10123903B2
公开(公告)日：2018-11-13
申请号：US11665321
申请日：2005-10-14
申请人： Reinhard Warnking , Yegor Sinelnikov
发明人： Reinhard Warnking , Yegor Sinelnikov
IPC分类号： A61B8/00 , A61F7/02 , A61B8/12 , A61B17/22 , A61B17/00 , A61B90/00
摘要： Ablation apparatus such as a catheter (10) carrying an ultrasonic ablation device (20) including an ablation transducer (42) and a balloon reflector structure (22, 24) for directing ultrasonic energy from the ablation transducer into a ring-like ablation region (A) is provided with an imaging ultrasonic transducer (86) mounted on an imaging probe (80) which may be inserted into or through a passageway (18, 65) extending through the catheter and into or through the ablation device to image the ablation region or neighboring regions. Alternatively, the imaging transducer (102, 202) may be mounted within the balloon reflector structure or distal to this structure.

6. 发明授权

US08698377B2 Dual-mode piezocomposite ultrasonic transducer 有权
标题翻译：双模式压电复合超声波换能器
公开(公告)号：US08698377B2
公开(公告)日：2014-04-15
申请号：US13201416
申请日：2011-05-20
申请人： Yegor Sinelnikov
发明人： Yegor Sinelnikov
IPC分类号： H01L41/18 , H04R17/00
CPC分类号： A61B8/4483 , A61B8/4494 , A61B8/485 , A61B2018/0016 , A61B2018/00577 , A61B2090/378 , A61N7/00 , A61N7/02 , A61N2007/0078 , B06B1/0629 , H01L41/09
摘要： A compact, high power, dual mode, emitting and receiving ultrasound transducer and method for applying ultrasonic energy within a living subject and for monitoring the effects it induces in tissue comprises a set of piezoelectric polymeric transducer elements and a set of piezoelectric ceramic elements, bonded together. The polymeric transducer elements have electrodes enabling their use for low power diagnostic imaging interrogation of the tissue and the ceramic transducer elements have electrodes enabling their use for high power therapy applications.
摘要翻译：一种紧凑，高功率，双重模式，发射和接收超声换能器以及在活体内施加超声波能量并用于监测其在组织中引起的影响的方法包括一组压电聚合物换能器元件和一组压电陶瓷元件，一起。聚合物换能器元件具有能够用于组织的低功率诊断成像询问的电极，并且陶瓷换能器元件具有能够用于高功率治疗应用的电极。

7. 发明申请

US20120143233A1 ULTRASONIC SURGICAL INSTRUMENT, ASSOCIATED SURGICAL METHOD AND RELATED MANUFACTURING METHOD 审中-公开
标题翻译：超声外科仪器，相关手术方法及相关制造方法
公开(公告)号：US20120143233A1
公开(公告)日：2012-06-07
申请号：US13307691
申请日：2011-11-30
申请人： Yegor SINELNIKOV
发明人： Yegor SINELNIKOV
IPC分类号： A61B17/32 , H05K13/00
CPC分类号： A61B17/320068 , A61B2017/00526 , A61B2017/00725 , A61B2017/320072 , A61B2017/320098 , Y10T29/49002
摘要： An ultrasonic therapeutic apparatus includes a handle, a horn or concentrator section terminating in an operative tip, and a transducer assembly set disposed in the handle and operatively engaged with the horn or concentrator section for generating ultrasonic mechanical vibrations therein to vibrate the operative tip during contact thereof with target tissue at a surgical site in a patient. An electrical waveform generator is operatively connected to the transducer assembly for energizing the transducer assembly set with one or more predetermined time reversal ultrasonic waveforms that, upon being applied to the transducer assembly set, result in respective predetermined patterns of motion of the operative tip.
摘要翻译：一种超声治疗装置包括一个终端于操作尖端的手柄，喇叭或集中器部分以及设置在手柄中并与喇叭或集中器部分可操作地接合的换能器组件，用于在接触期间产生超声机械振动以振动操作尖端其在患者的手术部位处的靶组织。电波形发生器可操作地连接到换能器组件，用于用一个或多个预定的时间反转超声波形来激励换能器组件组，其在施加到换能器组件组时导致操作尖端的相应的预定运动模式。

8. 发明授权

US07189229B2 Balloon alignment and collapsing system 有权
标题翻译：气球对齐和倒塌系统
公开(公告)号：US07189229B2
公开(公告)日：2007-03-13
申请号：US10635170
申请日：2003-08-06
申请人： Patrick David Lopath , Edward Paul Harhen , Yegor Sinelnikov , James D. Savage , Jaime Merino , John Hotmer
发明人： Patrick David Lopath , Edward Paul Harhen , Yegor Sinelnikov , James D. Savage , Jaime Merino , John Hotmer
IPC分类号： A61B18/04
CPC分类号： A61M25/10 , A61B17/2202 , A61B2017/22054 , A61B2017/22062 , A61M2025/1084 , A61N7/02
摘要： A balloon catheter is provided with a sleeve and a flexible material where, upon inflation of the balloon, the sleeve is slid over a ball joint, preventing the flexible material and tube from moving through a range of motion in order to prevent the tube from kinking and misaligning.
摘要翻译：球囊导管设置有套筒和柔性材料，其中当球囊膨胀时，套筒在球形接头上滑动，防止柔性材料和管移动通过一定范围的运动，以防止管扭结和不合格。

9. 发明申请

US20130060141A1 ULTRASONIC TRANSDUCER ASSEMBLY 有权
标题翻译：超声波传感器总成
公开(公告)号：US20130060141A1
公开(公告)日：2013-03-07
申请号：US13203771
申请日：2011-05-20
申请人： Yegor Sinelnikov
发明人： Yegor Sinelnikov
IPC分类号： A61B8/13 , A61N7/00
CPC分类号： A61B17/320068 , A61B8/12 , A61B8/4209 , A61B8/445 , A61B8/4488 , A61B8/4494 , G01N29/221 , G01N29/2437
摘要： An ultrasound transducer assembly includes an acoustic focusing lens and a therapy transducer mounted to a holder member so that the lens is movable relative to the transducer. The lens and the transducer are mounted to the holder member so that the lens is spaced a predetermined distance from the transducer element. A liquid layer having a thickness of the predetermined distance is provided between the lens and the transducer element. A solid backing member is disposed on a side of the transducer element opposite the lens. The backing member is spaced by an additional liquid layer of a predetermined thickness from the transducer element. The focusing depth of the lens-transducer assembly is controllable by transducer operating frequency.
摘要翻译：超声换能器组件包括声聚焦透镜和安装到保持器构件上的治疗换能器，使得透镜相对于换能器可移动。透镜和传感器安装到保持器构件，使得透镜与换能器元件间隔预定距离。在透镜和换能器元件之间设置具有预定距离厚度的液体层。固体背衬构件设置在与透镜相对的换能器元件的一侧。背衬构件与来自换能器元件的预定厚度的附加液体层隔开。透镜组件的聚焦深度可由传感器工作频率控制。

10. 发明申请

US20130060140A1 Dual-Mode Piezocomposite Ultrasonic Transducer 有权
标题翻译：双模式压电复合超声波传感器
公开(公告)号：US20130060140A1
公开(公告)日：2013-03-07
申请号：US13201416
申请日：2011-05-20
申请人： Yegor Sinelnikov
发明人： Yegor Sinelnikov
IPC分类号： A61B8/13 , A61N7/00
CPC分类号： A61B8/4483 , A61B8/4494 , A61B8/485 , A61B2018/0016 , A61B2018/00577 , A61B2090/378 , A61N7/00 , A61N7/02 , A61N2007/0078 , B06B1/0629 , H01L41/09
摘要： A compact, high power, dual mode, emitting and receiving ultrasound transducer and method for applying ultrasonic energy within a living subject and for monitoring the effects it induces in tissue comprises a set of piezoelectric polymeric transducer elements and a set of piezoelectric ceramic elements, bonded together. The polymeric transducer elements have electrodes enabling their use for low power diagnostic imaging interrogation of the tissue and the ceramic transducer elements have electrodes enabling their use for high power therapy applications.
摘要翻译：一种紧凑，高功率，双重模式，发射和接收超声换能器以及在活体内施加超声波能量并用于监测其在组织中引起的影响的方法包括一组压电聚合物换能器元件和一组压电陶瓷元件，一起。聚合物换能器元件具有能够用于组织的低功率诊断成像询问的电极，并且陶瓷换能器元件具有能够用于高功率治疗应用的电极。

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