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1. 发明专利

GB202013011D0 A human antiviraal, antibacterial, anti-aging liquid for oral administration and external application, using ion energy as ingredient 未知
公开(公告)号：GB202013011D0
公开(公告)日：2020-10-07
申请号：GB202013011
申请日：2020-08-20
申请人： XU TIAN , XU XIN

2. 实用新型

TWM591894U 小型旋轉等離子清洗機噴槍有权
简体标题：小型旋转等离子清洗机喷枪
公开(公告)号：TWM591894U
公开(公告)日：2020-03-11
申请号：TW108214416
申请日：2019-10-31
申请人：正鉑股份有限公司 , JUMBO APPLIED ENGINEERING CO., LTD. , 許天保 , XU, TIAN,BAO
发明人：許天保 , XU, TIAN,BAO
IPC分类号： B08B7/00 , B05B5/00

3. 发明申请

WO2020172266A1 TOPICAL RAPAMYCIN FORMULATIONS AND THEIR USE IN TREATING FACIAL ANGIOFIBROMAS AND OTHER SKIN DISORDERS 审中-公开
公开(公告)号：WO2020172266A1
公开(公告)日：2020-08-27
申请号：PCT/US2020/018816
申请日：2020-02-19
申请人： AI THERAPEUTICS, INC. , XU, Tian
发明人： XU, Tian , LICHENSTEIN, Henri , ROTHBERG, Jonathan M. , GROTZKE, Jeff , BECKETT, Paul , FANDRICK, Keith
IPC分类号： A61K9/06 , A61K47/32 , A61K47/38 , A61P17/02 , A61K31/436 , A61P17/00
摘要： The present disclosure provides gel compositions of rapamycin for topical administration and related compositions and methods including their use in the treatment of a skin condition, disease or disorder.

4. 发明申请

WO2010070094A1 MYOSTATIN BINDING PROTEINS 审中-公开
标题翻译：肌营养蛋白结合蛋白
公开(公告)号：WO2010070094A1
公开(公告)日：2010-06-24
申请号：PCT/EP2009/067515
申请日：2009-12-18
申请人： GLAXO GROUP LIMITED , ASHMAN, Claire , BEATON, Andrew , ELLIS, Jonathan, Henry , HAN, Bajin , KIRBY, Ian , KULL, Frederick , LEWIS, Alan , LINDLEY, Kathryn, Mason , ORECCHIA, Martin, Anibal , SHEN, Ying , WILSON, Paul , XU, Tian Shun , ZHANG, Hong
发明人： ASHMAN, Claire , BEATON, Andrew , ELLIS, Jonathan, Henry , HAN, Bajin , KIRBY, Ian , KULL, Frederick , LEWIS, Alan , LINDLEY, Kathryn, Mason , ORECCHIA, Martin, Anibal , SHEN, Ying , WILSON, Paul , XU, Tian Shun , ZHANG, Hong
IPC分类号： C07K16/22 , A61K39/395 , A61P21/00
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/76 , C07K2317/92
摘要： Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function.
摘要翻译：描述结合肌生长抑素的抗体结合蛋白，例如抗体，编码这种抗原结合蛋白的多核苷酸，包含所述抗原结合蛋白的药物组合物及其制备方法。此外，描述了这样的抗原结合蛋白在治疗或预防与肌肉质量，肌肉力量和肌肉功能降低的任何一种或组合相关的疾病中的用途。

5. 发明申请

WO2006122442A1 PIGGYBAC AS A TOOL FOR GENETIC MANIPULATION AND ANALYSIS IN VERTEBRATES 审中-公开
标题翻译： PIGGYBAC作为一种工具用于在VERTEBRATES进行遗传操作和分析
公开(公告)号：WO2006122442A1
公开(公告)日：2006-11-23
申请号：PCT/CN2005/000674
申请日：2005-05-14
申请人： FUDAN UNIVERSITY , XU, Tian , HAN, Min , ZHUANG, Yuan , WU, Xiaohui , DING, Sheng , LI, Gang
发明人： XU, Tian , HAN, Min , ZHUANG, Yuan , WU, Xiaohui , DING, Sheng , LI, Gang
IPC分类号： C12N9/22 , C12N15/85 , C12N5/16 , C12N5/22 , C12N15/09 , C12N15/86
CPC分类号： A01K67/0275 , A01K2217/05 , A01K2227/105 , A01K2267/03 , C12N15/8509 , C12N2800/90
摘要： The present invention relates to transgenic vertebrate, including mammalian, cells, whose genomes comprise one or more elements of the piggyBac family transposon system. Transgenic non-human vertebrates, including transgenic non-human mammals, whose genomes comprise one or more elements of the piggyBac family transposon system, are also provided. Methods of making and using the cells and animals of the invention, including applications in the medical, veterinary, and agricultural fields, are additionally provided. The present invention also relates to kits useful for practicing such methods.
摘要翻译：本发明涉及转基因脊椎动物，包括哺乳动物细胞，其基因组包含piggyBac家族转座子系统的一个或多个元件。还提供了转基因非人脊椎动物，包括转基因非人哺乳动物，其基因组包含piggyBac家族转座子系统的一个或多个元件。另外提供了制造和使用本发明的细胞和动物的方法，包括在医疗，兽医和农业领域中的应用。本发明还涉及可用于实施这些方法的试剂盒。

6. 发明申请

WO2005035729A2 A GENETIC SCREEN IN DROSOPHILA FOR METASTATIC BEHAVIOR 审中-公开
标题翻译：嗜人按蚊遗传学筛选转移行为的遗传学筛选
公开(公告)号：WO2005035729A2
公开(公告)日：2005-04-21
申请号：PCT/US2004/033310
申请日：2004-10-07
申请人： YALE UNIVERSITY , XU, Tian , PAGLIARINI, Raymond , IGAKI, Tatsushi
发明人： XU, Tian , PAGLIARINI, Raymond , IGAKI, Tatsushi
IPC分类号： C12N
CPC分类号： A01K67/0339 , A01K67/0271 , A01K2217/075 , A01K2227/706 , A01K2267/0331 , C07K14/4702 , C07K14/82 , C12N9/1205 , C12N15/8509 , C12N2800/30
摘要： The disclosure provides, among other things, assays for identifying compounds and genes that affect metastatic behavior of cells.
摘要翻译：本公开内容提供了用于鉴定影响细胞转移行为的化合物和基因的测定法等。

7. 发明申请

WO2021051135A1 PIKFYVE INHIBITORS FOR CANCER THERAPY 审中-公开
公开(公告)号：WO2021051135A1
公开(公告)日：2021-03-18
申请号：PCT/US2020/070522
申请日：2020-09-10
申请人： AI THERAPEUTICS, INC. , XU, Tian
发明人： LANDRETTE, Sean , BEEHARRY, Neil , YOUNG, Peter R. , ROTHBERG, Jonathan M. , LICHENSTEIN, Henri
IPC分类号： A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/44 , A61K31/4439 , A61K31/4523 , A61K31/4545 , A61K31/47 , A61K31/506 , A61K31/519 , A61K31/53 , A61K31/5377 , A61P35/00 , A61P35/04 , C12Q1/686 , C12Q2563/107
摘要： The present disclosure relates methods for treating a cancer having activated MET or RAS pathway signaling using an inhibitor of PIKfyve, alone or in combination with a MET inhibitor or a RAS pathway inhibitor, and related compositions and methods to identify PIKfyve inhibitor sensitive cancers for targeted treatment.

8. 发明申请

WO1996030402A1 NUCLEOTIDE AND PROTEIN SEQUENCES OF LATS GENES AND METHODS BASED THEREON 审中-公开
标题翻译：基因的核苷酸和蛋白质序列及其方法
公开(公告)号：WO1996030402A1
公开(公告)日：1996-10-03
申请号：PCT/US1996004101
申请日：1996-03-26
申请人： YALE UNIVERSITY , XU, Tian , TAO, Wufan , WANG, Weiyi , ZHANG, Sheng , YU, Wan
发明人： YALE UNIVERSITY
IPC分类号： C07K11/00
CPC分类号： C12N9/1205 , A61K38/00 , A61K48/00 , C07K14/43581 , C07K14/4703 , C07K2319/00 , C12N15/8206 , Y10S435/81 , Y10S435/925
摘要： The present invention relates to a tumor suppressor gene, termed large tumor suppressor (lats), and methods for identifying tumor suppressor genes. The method provides nucleotide sequences of lats genes, and amino acid sequences of their encoded proteins, as well as derivatives (e.g., fragments) and analogs thereof. In a specific embodiment, the lats protein is a human protein. The invention further relates to fragments (and derivatives and analogs thereof) of lats which comprise one or more domains of a lats protein. Antibodies to lats, its derivatives and analogs, are additionally provided. Methods of production of the lats proteins, derivatives and analogs, e.g., by recombinant means, are also provided. Therapeutic and diagnostic methods and pharmaceutical compositions are provided. The invention also relates to recombinant plants and animals and methods of increasing the growth of edible plants and animals. In specific examples, isolated lats genes, from Drosophila, mouse, and human, and the sequences thereof, are provided.
摘要翻译：本发明涉及称为大肿瘤抑制因子（lats）的肿瘤抑制基因，以及鉴定肿瘤抑制基因的方法。该方法提供了lat基因的核苷酸序列及其编码的蛋白质的氨基酸序列，以及衍生物（例如片段）及其类似物。在一个具体实施方案中，纬丝蛋白是人蛋白质。本发明进一步涉及包含一个或多个lat蛋白结构域的lat的片段（及其衍生物和类似物）。还提供了抗体，其衍生物和类似物的抗体。还提供了通过重组方法生产lat蛋白质，衍生物和类似物的方法。提供了治疗和诊断方法和药物组合物。本发明还涉及重组植物和动物以及增加可食用植物和动物生长的方法。在具体实例中，提供了来自果蝇，小鼠和人的分离的lat基因及其序列。

9. 发明申请

WO2021050362A1 TECHNIQUES FOR SEMI-SUPERVISED TRAINING AND ASSOCIATED APPLICATIONS 审中-公开
公开(公告)号：WO2021050362A1
公开(公告)日：2021-03-18
申请号：PCT/US2020/049280
申请日：2020-09-03
申请人： AI THERAPEUTICS, INC. , XU, Tian
发明人： LICHENSTEIN, Henri , PARRY, Bradley, Robert , ROTHBERG, Jonathan, M.
IPC分类号： G01N33/573 , C12Q1/70
摘要： Described herein are semi- supervised machine learning techniques and associated computer- implemented applications. Some aspects provide a system configured to identify associations among data input to the system. In some embodiments, the system may map the input data to one or more vector spaces, such that associated groups of the input data form associated clusters in the vector space(s). For example, the mapping may be performed by one or more trained encoders (e.g., neural network encoders) of the system. Accordingly, a distance separating two data entries in a space may indicate a likelihood of association among the data entries. Various applications of such systems are described herein.

10. 发明申请

WO2005035729A3 A GENETIC SCREEN IN DROSOPHILA FOR METASTATIC BEHAVIOR 审中-公开
标题翻译：用于分离行为的DROSOPHILA中的遗传筛选
公开(公告)号：WO2005035729A3
公开(公告)日：2005-07-07
申请号：PCT/US2004033310
申请日：2004-10-07
申请人： UNIV YALE , XU TIAN , PAGLIARINI RAYMOND , IGAKI TATSUSHI
发明人： XU TIAN , PAGLIARINI RAYMOND , IGAKI TATSUSHI
IPC分类号： A01K67/027 , A01K67/033 , C12N20060101 , C12N9/12
CPC分类号： A01K67/0339 , A01K67/0271 , A01K2217/075 , A01K2227/706 , A01K2267/0331 , C07K14/4702 , C07K14/82 , C12N9/1205 , C12N15/8509 , C12N2800/30
摘要： The disclosure provides, among other things, assays for identifying compounds and genes that affect metastatic behavior of cells.
摘要翻译：本公开尤其提供了用于鉴定影响细胞转移行为的化合物和基因的测定法。

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