专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4380625A Process for the preparation of purified aminoglycoside antibiotics 失效
标题翻译：制备纯化的氨基糖苷类抗生素的方法
公开(公告)号：US4380625A
公开(公告)日：1983-04-19
申请号：US220640
申请日：1980-12-29
申请人： Peter Stadler , Wolfgang Koebernick , Samir Samaan , Wolfgang Gau
发明人： Peter Stadler , Wolfgang Koebernick , Samir Samaan , Wolfgang Gau
IPC分类号： C07H15/234 , C07H15/236 , C07H15/22
CPC分类号： C07H15/234
摘要： The invention relates to an improved process for the isolation and purification of aminoglycoside antibiotics of Formula (I) as defined herein combining selective lipophilization of the compound of Formula (I) in the crude product obtained by fermentation with controlled liquid/liquid extraction.
摘要翻译：本发明涉及一种用于分离和纯化本发明定义的式（I）的氨基糖苷类抗生素的改进方法，该方法结合了通过用受控液/液萃取发酵获得的粗产物中式（I）化合物的选择性亲油化。

2. 发明授权

US4585782A Azole derivatives antimycotic agents which release the active compounds at a relatively high rate 失效
标题翻译：以相对高的速率释放活性化合物的唑衍生物抗真菌剂
公开(公告)号：US4585782A
公开(公告)日：1986-04-29
申请号：US581527
申请日：1984-02-21
申请人： Manfred Plempel , Manfred Bucheler , Wolfgang Gau , Erik Regel , Karl H. Buchel , Hans-Jurgen Ploschke
发明人： Manfred Plempel , Manfred Bucheler , Wolfgang Gau , Erik Regel , Karl H. Buchel , Hans-Jurgen Ploschke
IPC分类号： A61K9/00 , A61K31/415
CPC分类号： A61K9/0034 , A61K31/415
摘要： The invention relates to antimycotic compositions comprising (1) an antimycotic effective amount of an azole derivative having antimycotic activity, said azole derivative being in the form of particles less than 4.mu. in size, (2) an acid and/or a buffer system consisting of an organic acid and a salt thereof to provide a pH of 3 to 4 or less in aqueous solution and (3) an inert pharmaceutical carrier. Also included in the invention are methods for the short term treatment of vaginal infections utilizing the compositions of the invention.
摘要翻译：本发明涉及抗真菌组合物，其包含（1）抗真菌有效量的具有抗真菌活性的唑衍生物，所述唑衍生物的尺寸小于4μm的颗粒形式，（2）酸和/或缓冲系统的有机酸及其盐，以在水溶液中提供3至4或更低的pH，和（3）惰性药物载体。本发明还包括利用本发明组合物短期治疗阴道感染的方法。

3. 发明授权

US4233439A Glucopyranosido-1,6-mannitol, a process for producing the same and its use as a sugar substitute 失效
标题翻译：葡萄糖吡喃糖苷-1,6-甘露醇，其制备方法及其作为糖替代物的用途
公开(公告)号：US4233439A
公开(公告)日：1980-11-11
申请号：US21252
申请日：1979-03-16
申请人： Hubert Schiweck , Georg Steinle , Lutz Muller , Wolfgang Gau , Mohammad Munir
发明人： Hubert Schiweck , Georg Steinle , Lutz Muller , Wolfgang Gau , Mohammad Munir
IPC分类号： A23L27/30 , A61K31/7032 , B01J25/00 , C07B61/00 , C07H3/02 , C07H15/04 , C07K9/00 , C07H15/00 , C07H17/00
CPC分类号： C07H15/04 , Y10S426/804
摘要： Glucopyranosido-1,6-mannitol, represented by the formula: ##STR1## and a process for its preparation are provided. The glucopyranosido-1,6-mannitol is obtained by catalytically hydrogenating neutral aqueous solutions of isomaltulose and cooling the hydrogenated solution.In a second embodiment of the invention the use of the glucopyranosido-1,6-mannitol as a sugar substitute, sweetener for food or beverages, and sweetened food composition is provided.

4. 发明授权

US4117173A Use of glucopyranosido-1,6-mannitol as a sugar substitute 失效
标题翻译：葡萄糖苷-1,6-二硝基苯酚作为糖代用品的使用
公开(公告)号：US4117173A
公开(公告)日：1978-09-26
申请号：US682674
申请日：1976-05-03
申请人： Hubert Schiweck , Georg Steinle , Lutz Muller , Wolfgang Gau , Mohammad Munir
发明人： Hubert Schiweck , Georg Steinle , Lutz Muller , Wolfgang Gau , Mohammad Munir
IPC分类号： A23L27/30 , A61K31/7032 , B01J25/00 , C07B61/00 , C07H3/02 , C07H15/04 , C07K9/00 , A23L1/236
CPC分类号： C07H15/04 , Y10S426/804
摘要： Glucopyranosido-1,6-mannitol, represented by the formula: ##STR1## and a process for its preparation are provided. The glucopyranosido-1,6-mannitol is obtained by catalytically hydrogenating neutral aqueous solutions of isomaltulose and cooling the hydrogenated solution.In a second embodiment of the invention the use of the glucopyranosido-1,6-mannitol as a sugar substitute, sweetener for food or beverages, and sweetened food composition is provided.
摘要翻译：提供由下式表示的吡喃葡萄糖苷 - 1,6-甘露糖醇及其制备方法。通过催化氢化异麦芽酮糖的中性水溶液并冷却氢化溶液获得吡喃葡萄糖苷-1,6-甘露糖醇。在本发明的第二个实施方案中，提供了吡喃葡萄糖苷-1,6-甘露糖醇作为糖替代物，食品或饮料的甜味剂和甜味食品组合物的用途。

5. 发明授权

US06384186B2 Cyclic dodecapeptide and process for the preparation thereof 失效
标题翻译：环十二肽及其制备方法
公开(公告)号：US06384186B2
公开(公告)日：2002-05-07
申请号：US09077489
申请日：1998-05-29
申请人： Heidrun Anke , Winfried Etzel , Wolfgang Gau , Rüdiger Hain , Michael Kilian , Anke Mayer , Olov Sterner
发明人： Heidrun Anke , Winfried Etzel , Wolfgang Gau , Rüdiger Hain , Michael Kilian , Anke Mayer , Olov Sterner
IPC分类号： C07K708
CPC分类号： C07K7/64 , A61K38/00
摘要： The present invention relates to a novel organochemical compound, referred to as omphalotin for short, a process for its preparation by an essentially microbiological route and its use as microbicide and pesticide, preferably for controlling animal pests, harmful fungi and bacteria.
摘要翻译：本发明涉及一种新的有机化合物，简称为奥马林，其通过基本上微生物学途径制备的方法及其作为杀微生物剂和农药的用途，优选用于防治动物害虫，有害真菌和细菌。

6. 发明授权

US4450297A Preparation of o-nitrobenzaldehyde 失效
标题翻译：邻硝基苯甲醛的制备
公开(公告)号：US4450297A
公开(公告)日：1984-05-22
申请号：US476093
申请日：1983-03-17
申请人： Michael Preiss , Wolfgang Gau , Horst Behre
发明人： Michael Preiss , Wolfgang Gau , Horst Behre
IPC分类号： C07C201/16 , C07C20060101 , C07C45/78 , C07C67/00 , C07C201/00 , C07C205/44 , C07C76/06 , C07C79/36
CPC分类号： C07C201/12 , C07C201/16
摘要： A process for the preparation of o-nitrobenzaldehyde, comprising converting to the corresponding acetals a mixture of nitrated benzaldehyde which contains about 10 to 30% of o-nitrobenzaldehyde and about 70 to 90% of m-nitrobenzaldehyde, removing the o-nitrobenzaldehyde acetal by distillation, and then converting the o-nitrobenzaldehyde acetal to o-nitrobenzaldehyde.
摘要翻译：一种制备邻硝基苯甲醛的方法，包括将相应的缩醛转化成含有约10-30％邻硝基苯甲醛的硝化苯甲醛和约70-90％间硝基苯甲醛的混合物，通过以下步骤除去邻硝基苯甲醛缩醛蒸馏，然后将邻硝基苯甲醛缩醛转化为邻硝基苯甲醛。

7. 发明授权

US4173645A Substituted 4,5-dihydroxy-imidazolidine-2-thiones and their use as ectoparasiticides 失效
标题翻译：取代的4,5-二羟基 - 咪唑烷-2-硫堇及其作为外寄生虫杀螨剂
公开(公告)号：US4173645A
公开(公告)日：1979-11-06
申请号：US858917
申请日：1977-12-08
申请人： Edgar Enders , Volker Ebbighausen , Wolfgang Gau , Christian Wunsche , Wilhelm Stendel
发明人： Edgar Enders , Volker Ebbighausen , Wolfgang Gau , Christian Wunsche , Wilhelm Stendel
IPC分类号： C07D233/42 , C07D233/02 , A01N9/22
CPC分类号： C07D233/42
摘要： The present invention provides, as compounds, the substituted 4,5-dihydroxy-imidazolidine-2-thiones of the general formula ##STR1## in which R.sup.1, R.sup.2 and R.sup.3, which are selected independently of one another each represent hydrogen, optionally substituted alkyl, optionally substituted alkoxy or halogen andR.sup.4 represents optionally substituted alkyl, cycloalkyl or alkenyl.It has been found that the compounds of this invention have a powerful ectoparasiticidal action, in particular against acarids.
摘要翻译：本发明提供了作为化合物的通式（I）的取代的4,5-二羟基 - 咪唑烷-2-硫酮，其中彼此独立地彼此选择的R 1，R 2和R 3各自代表氢，任选地取代的烷基，任选取代的烷氧基或卤素，R 4表示任选取代的烷基，环烷基或烯基。已经发现本发明的化合物具有强大的杀寄生作用，特别是针对螨虫。

8. 发明授权

US4562274A Process for the preparation and isolation of polyglycidyl compounds 失效
标题翻译：聚缩水甘油基化合物的制备和分离方法
公开(公告)号：US4562274A
公开(公告)日：1985-12-31
申请号：US560358
申请日：1983-12-12
申请人： Gebhard Rauleder , Helmut Waldmann , Ludwig Bottenbruch , Hans-Joachim Traenckner , Wolfgang Gau
发明人： Gebhard Rauleder , Helmut Waldmann , Ludwig Bottenbruch , Hans-Joachim Traenckner , Wolfgang Gau
IPC分类号： C07D301/32 , C07D303/16 , C07D405/06 , C07D405/14 , C08G59/00 , C08G59/20 , C07D301/14
CPC分类号： C07D405/14 , C07D303/16 , C07D405/06
摘要： Polyglycidyl compounds are prepared by reacting certain polyallyl compounds with a percarboxylic acid containing 3 or 4 C atoms, subsequently removing, by distillation, the carboxylic acid formed from the percarboxylic acid, then separating the remaining mixture by simultaneous extraction with a lipophilic and a hydrophilic phase, subsequently working up the laden lipophilic phase and the laden hydrophilic phase separately in a manner which is known per se, and obtaining the polyglycidyl compound as the residue from working up of the laden hydrophilic phase.
摘要翻译：多缩水甘油基化合物是通过使某些聚烯丙基化合物与含有3或4个C原子的过羧酸反应制备的，随后通过蒸馏除去由过羧酸形成的羧酸，然后通过亲脂性和亲水相同时萃取分离剩余的混合物然后以本身已知的方式分别加载负载的亲油相和负载亲水相，并获得聚缩水甘油基化合物作为负载的亲水相的加工残留物。

9. 发明授权

US06518296B1 Substituted 3-thiocarbamoylpyrazoles 失效
标题翻译：取代的3-硫代氨基甲酰基吡唑
公开(公告)号：US06518296B1
公开(公告)日：2003-02-11
申请号：US09701364
申请日：2000-11-28
申请人： Bernd Alig , Albrecht Marhold , Jörn Stölting , Wolfgang Gau , Christoph Erdelen , Andreas Turberg , Norbert Mencke , Olaf Hansen
发明人： Bernd Alig , Albrecht Marhold , Jörn Stölting , Wolfgang Gau , Christoph Erdelen , Andreas Turberg , Norbert Mencke , Olaf Hansen
IPC分类号： A01N4356
CPC分类号： C07D401/04 , C07D231/44
摘要： The invention relates to novel substituted 3-thiocarbamoylpyrazoles of general formula (I), wherein m, n, R1, R2, R3 and Ar have the meanings cited in the description. The invention further relates to methods for the production and use thereof as pesticides.
摘要翻译：本发明涉及通式（I）的新型取代的3-硫代氨基甲酰基吡唑，其中m，n，R1，R2，R3和Ar具有说明书中引用的含义。本发明还涉及作为农药生产和使用的方法。

10. 发明授权

US5686392A Process for preparing substituted N-carbamoyl-Tetrazolinones 失效
标题翻译：取代的N-氨基甲酰基 - 四唑啉酮的制备方法
公开(公告)号：US5686392A
公开(公告)日：1997-11-11
申请号：US595088
申请日：1996-02-01
申请人： Uwe Stelzer , Wolfgang Gau , Karl-Julius Reubke
发明人： Uwe Stelzer , Wolfgang Gau , Karl-Julius Reubke
IPC分类号： A01N47/38 , B01J31/02 , C07D257/04
CPC分类号： C07D257/04
摘要： The herbicidally active substituted N-carbamoyl-tetrazolinones of the formula (I) ##STR1## in which R.sup.1 represents, inter alia, an (optionally substituted) phenyl radical, R.sup.2 represents, inter alia, an alkyl radical, and R.sup.3 represents, inter alia, a cycloalkyl radical, are obtained in very good yields and at high purity--i.e. free from the isomeric O-carbamoyloxytetrazoles (Ia)--by reacting tetrazolinones of the formula (II) with carbamoyl halides of the formula (III) (X=halogen) ##STR2## in the presence of an acid acceptor and in the presence of a diluent, at temperatures of between 0.degree. C. and 200.degree. C., and either isomerizing the O-carbamoylation product of the formula (Ia), which is formed under these circumstances as a byproduct, into the desired product of the formula (I) by heating, or else converting it by hydrolysis or alcoholysis into water-soluble, and thus readily separable, components (variable (a)). Three variants (b), (c) and (d) which are closely related to this process (a) are also described: Process variant (b) proceeds in analogy with (a) but via the (novel, isolated) metal salts (IIa) of the tetrazolinones (II). In variant (c), the isomer (Ia) is isomerized thermally, either in pure isolated form or mixed with (I), while, in variant (d), the (Ia) isomer is removed from (I)/(Ia) mixtures by means of hydrolysis or alcoholysis. The novel intermediates (Ia) and (IIa) also belong, as such, to the subject-matter of the invention.
摘要翻译：式（I）的除草活性的取代的N-氨基甲酰基 - 四唑啉酮，其中R 1特别是（任选取代的）苯基，R 2特别包括，烷基，和R3代表环烷基，以非常好的产率和高纯度获得，即通过使式（II）的四唑啉酮与式（III）的氨基甲酰基卤化物（X =卤素）在酸受体的存在下反应而不存在异构O-氨基甲酰氧基四唑（Ia）稀释剂，在0℃至200℃的温度下，将在这些情况下作为副产物形成的式（Ia）的O-氨基甲酰基化产物异构化为所需的式（I ），或者通过水解或醇解将其转化为水溶性的，因此易于分离的组分（可变（a））。还描述了与该方法（a）密切相关的三个变体（b），（c）和（d）：方法变体（b）类似于（a）进行，但通过（新颖的，分离的）金属盐 IIa）四唑啉酮（II）。在变体（c）中，异构体（Ia）以纯分离形式或与（I）混合而异构化，而在变体（d）中，（Ia）异构体从（I）/（Ia）混合物通过水解或醇解。新颖的中间体（Ia）和（IIa）也属于本发明的主题。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式