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1. 发明申请

US20080264324A1 Motor Boat 有权
标题翻译：汽艇
公开(公告)号：US20080264324A1
公开(公告)日：2008-10-30
申请号：US12105368
申请日：2008-04-18
申请人： Michael Preiss
发明人： Michael Preiss
IPC分类号： B63B38/00
CPC分类号： B63B15/00 , B63B17/02
摘要： A motorboat, in particular a yacht, with a cabin which merges on a rear side into a cockpit which is delimited laterally by side sections. To improve the wind comfort in the cockpit, a respective side guiding element for guiding the flow is disposed on each side of the boat. The side guiding element extends generally vertically upward and generally in the longitudinal direction of the boat from a rear end section of the respective side section.
摘要翻译：一艘摩托艇，特别是一艘游艇，有一个舱室，它在后侧合并成一个由侧面横向分界的驾驶舱。为了改善驾驶舱中的风舒适性，在船的每一侧设置有用于引导流动的相应侧引导元件。侧引导元件从相应侧部分的后端部分大致垂直向上并且大致在船的纵向方向上延伸。

2. 发明授权

US07226117B2 Rear-end spoiler for a full-rear vehicle 有权
标题翻译：用于全后车辆的后端扰流板
公开(公告)号：US07226117B2
公开(公告)日：2007-06-05
申请号：US11136424
申请日：2005-05-25
申请人： Michael Preiss
发明人： Michael Preiss
IPC分类号： B60R27/00
CPC分类号： B62D35/007
摘要： In a full-rear vehicle, a rear-end spoiler is situated in the rear edge area of the roof above a rear window. To optimize a rear-end spoiler with a given longitudinal extent so that the aerodynamic efficiency is increased, the spoiler is formed by a split wing.
摘要翻译：在全后车辆中，后端扰流板位于后窗后方的屋顶后缘区域。为了优化具有给定纵向范围的后端扰流器，使得空气动力学效率增加，扰流器由分裂翼形成。

3. 发明授权

US06357562B1 Aerodynamic wheel-bearing housing 失效
标题翻译：气动轮毂轴承座
公开(公告)号：US06357562B1
公开(公告)日：2002-03-19
申请号：US09659064
申请日：2000-09-11
申请人： Vilem Toman , Michael Preiss , Bernhard Jost , Thomas Wiegand
发明人： Vilem Toman , Michael Preiss , Bernhard Jost , Thomas Wiegand
IPC分类号： F16D6578
CPC分类号： F16D55/22 , B60G2200/142 , B60G2204/129 , B60G2206/50 , B60G2206/7102 , B60G2206/8101 , B60T1/065 , F16D65/847
摘要： A wheel bearing housing for suspending a wheel of a vehicle is provided. The wheel, mounted at the wheel bearing housing, is provided with a brake device. In order to create a wheel suspension device which has devices for guiding air that are provided at low construction costs, it is provided that the outside of the wheel bearing housing is formed at least regionally as an air-guiding element.
摘要翻译：提供了用于悬挂车轮的车轮轴承壳体。安装在车轮轴承壳体上的车轮设有制动装置。为了制造具有用于以低建筑成本提供的用于引导空气的装置的轮悬挂装置，其设置在车轮轴承壳体的外部至少在区域上形成为空气引导元件。

4. 发明授权

US6116365A Arrangement for ventilating an assembly on a vehicle 失效
标题翻译：在车辆上组装通风的安排
公开(公告)号：US6116365A
公开(公告)日：2000-09-12
申请号：US109940
申请日：1998-07-02
申请人： Michael Preiss , Thomas Wiegand
发明人： Michael Preiss , Thomas Wiegand
IPC分类号： B62D35/00 , B62D35/02 , B60K11/08
CPC分类号： B62D35/02 , Y10S180/903
摘要： For increasing the effectiveness of an arrangement for ventilating an assembly on a vehicle, it is provided that, upstream of the assembly to be ventilated, an air guiding element is arranged which, in the cross-sectional view, has a vane-type profile and is set to be relatively steep, and on which an upper air guiding channel and a lower air guiding channel are constructed for the air stream occurring in the driving operation.
摘要翻译：为了提高在车辆上组装通风的布置的有效性，设置在要通风的组件的上游，布置空气引导元件，其在横截面图中具有叶片型轮廓，并且设置为相对陡峭，并且在驱动操作中为空气流构造上空气引导通道和下空气引导通道。

5. 发明授权

US5836643A Vehicle roof 失效
标题翻译：车顶
公开(公告)号：US5836643A
公开(公告)日：1998-11-17
申请号：US951167
申请日：1997-10-15
申请人： Michael Preiss
发明人： Michael Preiss
IPC分类号： B60J7/22
CPC分类号： B60J7/22
摘要： A vehicle roof has a first pivotable roof section, adjacent to a windshield frame, and a following roof opening. To avoid booming in the passenger compartment when driving, at least one upwardly projecting air baffle of limited width is provided on the outside of the first roof section.
摘要翻译：车顶具有与挡风玻璃框架相邻的第一可枢转的屋顶部分和随后的屋顶开口。为了避免在驾驶时在乘客舱中飞行，在第一屋顶部分的外侧设有至少一个有限宽度的向上伸出的空气挡板。

6. 发明授权

US5095112A Process for the preparation of quinolonecarboxylic acid esters 失效
标题翻译：制备喹喔啉羧酸酯的方法
公开(公告)号：US5095112A
公开(公告)日：1992-03-10
申请号：US121502
申请日：1987-11-17
申请人： Michael Preiss
发明人： Michael Preiss
IPC分类号： A61K31/47 , A61P31/04 , C07D215/56 , C07D455/04 , C07D471/04 , C07D471/06 , C07D498/04 , C07D498/06
CPC分类号： C07D215/56 , C07D455/04 , C07D471/04 , C07D471/06
摘要： A process for the preparation of quinolone-carboxylic acid esters of the formulae I and II ##STR1## in which A represents nitrogen or .dbd.C--R.sup.4,R.sup.4 represents hydrogen, fluorine, chlorine, nitro or methyl,B represents halogen, nitro, alkoxy, alkylsulphonyloxy or the radical ##STR2## and B additionally represents ##STR3## if R1 does not denote cyclopropyl, and R.sup.5 represents a branched or unbranched alkyl group which has 1 to 4 carbon atoms and which can optionally be substituted by a hydroxyl or methoxy group,R.sup.6 represents hydrogen, methyl or phenyl,R.sup.7 represents hydrogen or methyl,R.sup.8 represents dialkylamino having 1 or 2 carbon atoms in the alkyl group or dialkylaminomethyl having 1 or 2 carbon atoms in the alkyl group, or aminomethylR.sup.1 represents hydrogen, optionally substituted alkyl having 1 to 3 carbon atoms, optionally substituted cycloalkyl, 2-fluoroethyl, vinyl, methoxy or 4-fluorophenyl,R.sup.2 represents optionally substituted alkyl having 1 to 6 carbon atoms and also cyclohexyl and benzyl,R.sup.3 represents hydrogen, methyl or ethyl, andZ represents oxygen, nitrogen which is substituted by methyl or phenyl, and .dbd.CH.sub.2,characterized in that quinolonecarboxylic acids of the formulae III and IV ##STR4## in which A, B, Z, R.sup.1 and R.sup.3 have the meanings indicated above, are reacted with chloroformic acid esters of the formula VCl--COOR.sup.2 (V)in which R.sup.2 has the meaning indicated above.
摘要翻译：一种制备式I和II的喹诺酮 - 羧酸酯的方法，其中A表示氮或= C-R 4，R 4表示氢，氟，氯，硝基或甲基，B表示卤素，硝基，烷氧基，烷基磺酰氧基或基团，且如果R1不表示环丙基，则B另外表示“IMAGE”，R 5表示具有1至4个碳原子的支链或非支链烷基，任选被羟基或甲氧基取代，R 6表示氢，甲基或苯基，R 7表示氢或甲基，R 8表示烷基中具有1或2个碳原子的二烷基氨基或烷基中具有1或2个碳原子的二烷基氨基甲基，或氨基甲基R 1表示氢，任选取代的具有1至3个碳原子的烷基，任选取代的环烷基，2-氟乙基，乙烯基，甲氧基或4-氟苯基，R 2表示任选取代的具有1至6个碳原子的烷基和因此环己基和苄基，R 3表示氢，甲基或乙基，Z表示氧，被甲基或苯基取代的氮和= CH 2，其特征在于式III和IV的喹诺酮羧酸（图III）其中A，B，Z，R 1和R 3具有上述含义的式（Ⅳ）与式ⅤCl-COOR2（Ⅴ）的氯甲酸酯反应，其中R2具有上述含义。

7. 发明授权

US4973590A Process for the preparation of quinolonecarboxylic acids which can be administered parenterally 失效
标题翻译：可以肠胃外给药的喹诺酮羧酸的制备方法
公开(公告)号：US4973590A
公开(公告)日：1990-11-27
申请号：US181809
申请日：1988-04-15
申请人： Michael Preiss , Ulrich Schorsch , Arthur Haaf , Paul Naab , Rudolf Zerbes
发明人： Michael Preiss , Ulrich Schorsch , Arthur Haaf , Paul Naab , Rudolf Zerbes
IPC分类号： A61K31/47 , A61P31/04 , C07D215/56 , C07D401/04 , C07D455/04 , C07D471/04
CPC分类号： C07D215/56 , A61K31/47
摘要： Known quinolone carboxylic acid derivatives of the formula ##STR1## are treated so as to become readily administrable parenterally, the treatment comprising dissolving the active compound using an acid, allowing the solution to stand for about 0.15 to 150 hours at a temperature from room temperature to the boiling point of the solution, filtering the solution, precipitating the active compound from the solution using a basic reagent, and converting the precipitated active compound into a form which can be administered parenterally.
摘要翻译：处理具有式“IMAGE”的已知喹诺酮羧酸衍生物以使其易于肠胃外施用，该处理包括使用酸溶解活性化合物，使该溶液在室温至室温下静置约0.15至150小时溶液的沸点，过滤溶液，使用碱性试剂从溶液中沉淀活性化合物，并将沉淀的活性化合物转化成可肠胃外给药的形式。

8. 发明授权

US4338434A 2-Hetero-acetamido-cephalosporinates 失效
标题翻译： 2-异乙酰氨基头孢菌素
公开(公告)号：US4338434A
公开(公告)日：1982-07-06
申请号：US45474
申请日：1979-06-04
申请人： Michael Preiss , Hans-Bodo Konig , Karl G. Metzger , Peter Feyen
发明人： Michael Preiss , Hans-Bodo Konig , Karl G. Metzger , Peter Feyen
IPC分类号： A61K31/43 , A61K31/545 , A61K31/546 , A61P31/04 , C07D231/12 , C07D277/20 , C07D277/48 , C07D307/54 , C07D499/00 , C07D499/64 , C07D499/68 , C07D499/70 , C07D501/20 , C07D501/34 , C07D501/46 , C07D501/57
CPC分类号： C07D231/12 , C07D277/48 , C07D277/587 , C07D307/54 , C07D499/00
摘要： 2-Hetero-acetamido-penicillanates and cephalosporinates of the formula ##STR1## in which R is hydrogen or lower alkoxy,Z is ##STR2## R.sup.1 and R .sup.2 independently or together are various radicals, A is --CH.sub.2 --CH.sub.2 --,--CH.sub.2 --CH.sub.2 --CH.sub.2 -- or ##STR3## n is 1 or 2, X is S,O,SO,SO.sub.2 or --CH.sub.2 --,Y is the balance of a penicillin or cephalosporin moiety, andB is a heterocyclic radical, in the form of the acid, a hydrate thereof, a salt thereof or a salt of the hydrate, exhibit marked anti-bacterial properties rendering them suited for use as antibiotics and animal feed supplements.
摘要翻译：其中R为氢或低级烷氧基的式“IMAGE”的2-异 - 乙酰氨基 - 青霉烷酸和头孢菌素，Z为独立地或一起为不同的基团，A为-CH 2 -CH 2 - ， - CH 2 -CH 2 -CH 2 - 或 n为1或2，X为S，O，SO，SO 2或-CH 2 - ，Y为青霉素或头孢菌素部分的余量，B为杂环基，的酸，其水合物，其盐或水合物的盐表现出显着的抗菌性质，使其适合用作抗生素和动物饲料添加剂。

9. 发明授权

US4182762A Dioxopiperazine derivatives suitable for use as medicaments and .beta.-lactam antibiotic intermediates 失效
标题翻译：适用于药物和β-内酰胺抗生素中间体的二氧代哌嗪衍生物
公开(公告)号：US4182762A
公开(公告)日：1980-01-08
申请号：US861473
申请日：1977-12-16
申请人： Michael Preiss
发明人： Michael Preiss
IPC分类号： C07D241/08 , C07D405/12 , C07D499/00 , C07D499/68 , C07D241/02 , C07D405/02 , C07D409/02
CPC分类号： C07D499/00 , C07D241/08
摘要： New dioxo-piperazine derivatives suitable for use as medicaments and .beta.-lactam antibiotic intermediates of the formula ##STR1## in which Z is ##STR2## and, R.sup.1 and R.sup.2 each independently is hydrogen or various optionally substituted aliphatic, aromatic or heterocyclic radicals or together form an optionally substituted ring,are formed by reacting(a) 1-amino-2,3-dioxo-piperazine of the formula ##STR3## with a compound of the formula ##STR4## or a hydrate, acetal, ketal, sulphite, hydrogen halide or hydrocyanic acid addition product thereof or, ##STR5## with an oxalic acid ester in the presence of a diluent, thereby to effect cyclization. The new derivatives are anti-virally active and can also be chlorocarbonated with phosgene to form a reactive derivative which can be condensed with the amino group of .alpha.-amino penicillins to form antibiotics.
摘要翻译：适合用作药物的新二氧代哌嗪衍生物和其中Z为的式“IMAGE”的β-内酰胺抗生素中间体，R1和R2各自独立地为氢或各种任选取代的脂族，芳族或杂环基或一起形成任选取代的环，通过使（a）式（Ⅰa）的1-氨基-2,3-二氧代 - 哌嗪与下式化合物或水合物，缩醛，缩酮，亚硫酸盐，氢气卤化物或氢氰酸加成产物，或b）与草酸酯在稀释剂存在下进行环化反应。新衍生物具有抗病毒活性，也可用光气进行氯碳化，形成可与α-氨基青霉素氨基缩合形成抗生素的活性衍生物。

10. 发明授权

US4107304A Oxo-imidazolidine substituted cephalosporins and antibacterial compositions and methods of combatting bacteria employing them 失效
标题翻译：氧代 - 咪唑烷取代的头孢菌素和抗菌组合物和使用它们的抗菌药物的方法
公开(公告)号：US4107304A
公开(公告)日：1978-08-15
申请号：US590794
申请日：1975-06-27
申请人： Wilfried Schrock , Hans-Bodo Konig , Michael Preiss , Karl Georg Metzger , Michael Walkowiak
发明人： Wilfried Schrock , Hans-Bodo Konig , Michael Preiss , Karl Georg Metzger , Michael Walkowiak
IPC分类号： A61K31/545 , C07D501/20 , C07D501/24 , C07D501/34
CPC分类号： C07D501/20
摘要： Cephalosporins of the formula ##STR1## their pharmaceutically-acceptable, nontoxic salts, and hydrates thereof are produced, whereinA is hydrogen; unsubstituted or substituted alkyl; aryl; or R.sub.1 --X--, whereinX is --CO-- or --SO.sub.2 --, andR.sub.1 is hydrogen, unsubstituted or substituted alkyl; aryl; thienyl; furyl; amino; alkylamino; dialkylamino; pyrrolidyl; or piperidyl;Or whenX is --CO--,R.sub.1 can also be alkoxy;B is phenyl, methylphenyl, chlorophenyl, hydroxyphenyl or the moiety ##STR2## E is hydrogen, hydroxyl or acetoxy; and C is a center of chirality.These compounds are particularly useful for their antimicrobial and, particularly, antibacterial effects.
摘要翻译：生产下式的头孢菌素：其药学上可接受的无毒盐及其水合物，其中A是氢; 未取代或取代的烷基; 芳基; 或R 1 -X-，其中X是-CO-或-SO 2 - ，并且R 1是氢，未取代或取代的烷基; 芳基; 噻吩基呋喃氨基; 烷基氨基; 二烷基氨基; 吡咯烷基或哌啶基; 或当X为-CO-时，R 1也可为烷氧基; B是苯基，甲基苯基，氯苯基，羟基苯基或部分E是氢，羟基或乙酰氧基; C是手性的中心。

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