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1. 发明申请

US20120226343A1 STENT DELIVERY SYSTEM 审中-公开
标题翻译： STENT交付系统
公开(公告)号：US20120226343A1
公开(公告)日：2012-09-06
申请号：US13411340
申请日：2012-03-02
申请人： Justin Vo , Michael Spencer , Sargon Bourang , William S. Henry , Hong Doan , Hanh Doan
发明人： Justin Vo , Michael Spencer , Sargon Bourang , William S. Henry , Hong Doan , Hanh Doan
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/9583 , A61F2002/9665
摘要： A stent delivery system includes a delivery member, a frictional interfacing member disposed on a distal region of the delivery member, the frictional interfacing member comprising a plurality of perfusion channels, a self-expanding stent disposed over the respective frictional interfacing member and delivery member in a radially contracted configuration, and a sheath defining disposed over the respective self-expanding stent, frictional interfacing member, and delivery member, wherein the frictional interfacing member resists axial and/or rotational movement of the stent relative to the delivery member while the stent is in its radially contracted configuration, and wherein the perfusion channels permit fluid to flow from an interior region of the sheath proximal of the frictional interfacing member to an interior region of the sheath distal of the frictional interfacing member.
摘要翻译：支架输送系统包括输送构件，设置在输送构件的远侧区域上的摩擦接口构件，摩擦接口构件包括多个灌注通道，设置在相应摩擦接口构件和输送构件上方的自扩张支架径向缩小的构造，以及限定设置在相应的自扩张支架，摩擦接口构件和输送构件上方的护套，其中所述摩擦接口构件抵抗支架相对于输送构件的轴向和/或旋转运动，而支架是在其径向收缩构造中，并且其中所述灌注通道允许流体从所述摩擦接合构件的近侧的护套的内部区域流动到所述护套远离所述摩擦接合构件的内部区域。

2. 发明授权

US07468070B2 Stent delivery catheter 失效
标题翻译：支架输送导管
公开(公告)号：US07468070B2
公开(公告)日：2008-12-23
申请号：US10764054
申请日：2004-01-23
申请人： William S. Henry , John E. Ortiz
发明人： William S. Henry , John E. Ortiz
IPC分类号： A61F2/06
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966
摘要： A self-expanding stent delivery assembly includes a shaft having a proximal end, a distal end, a distal region, a lumen, and a longitudinal axis. A retractable sheath having an outer surface, a proximal end and a distal end is co-axially disposed around the shaft distal region. A stent is disposed co-axially between the shaft and the retractable sheath. A tubular tapered tip is affixed to the retractable sheath distal end. The tubular tapered tip has an elongate region predisposed to fracturing. Methods of delivering a self-expanding stent are also described.
摘要翻译：自扩张支架输送组件包括具有近端，远端，远侧区域，内腔和纵向轴线的轴。具有外表面，近端和远端的可伸缩护套共轴地设置在轴远侧区域周围。支架同轴地设置在轴和可缩回护套之间。管状锥形尖端固定到可缩回护套远端。管状锥形尖端具有易于断裂的细长区域。还描述了递送自扩张支架的方法。

3. 发明授权

US09636115B2 Vaso-occlusive delivery device with kink resistant, flexible distal end 有权
公开(公告)号：US09636115B2
公开(公告)日：2017-05-02
申请号：US11423934
申请日：2006-06-13
申请人： William S. Henry , Charles Daly , Russell Ford , Michael D. Williams , Hanh Duong , Hughie Devaney , Kamal Ramzipoor , Clifford Teoh , Richard Murphy , Andrew Huffmaster , Scott McGill
发明人： William S. Henry , Charles Daly , Russell Ford , Michael D. Williams , Hanh Duong , Hughie Devaney , Kamal Ramzipoor , Clifford Teoh , Richard Murphy , Andrew Huffmaster , Scott McGill
IPC分类号： A61M29/00 , A61B17/12 , A61M25/09
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12154 , A61B2017/1205 , A61B2017/12054 , A61B2017/12063 , A61M25/09 , A61M2025/09133
摘要： A device for delivering an occlusive element includes an elongate sheath having a lumen therein. An elongate core member is disposed within the lumen and is formed from a proximal portion and distal portion connected via a joint. The distal portion of the elongate member includes a severable junction secured to the occlusive element. A marker coil is coaxially arranged around the distal portion of the elongate core member and is partially disposed inside the sheath lumen. A coil member is coaxially arranged around the distal portion of the elongate core member and coaxially arranged around at least a portion of the marker coil extending outside the lumen of the sheath. The coil member is secured at a distal end thereof to the distal portion of the elongate core member. The device resists axial compression while allowing for radial bending.

4. 发明申请

US20100318171A1 Multiple Stent Delivery System 审中-公开
标题翻译：多支架输送系统
公开(公告)号：US20100318171A1
公开(公告)日：2010-12-16
申请号：US12796562
申请日：2010-06-08
申请人： Stephen Porter , William S. Henry
发明人： Stephen Porter , William S. Henry
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/91 , A61F2002/826 , A61F2210/0076
摘要： A stent delivery system includes a delivery wire, a first stent, a second stent, and a sheath. The first stent may be disposed around a portion of a distal region of the delivery wire in a radially contracted configuration and the second stent may be disposed around a portion of the distal region of the delivery wire in a radially contracted configuration. In some cases, the first stent and the second stent may be disposed in a tandem arrangement with the first stent distal of the second stent. The sheath may be slidably disposed around the delivery wire, the first stent, and the second stent. The sheath may be retractable relative to the delivery wire to deploy the first stent and the second stent. In some embodiments, the first stent and the second stent may be sequentially deployed in an overlapping arrangement at the target site in the vessel.
摘要翻译：支架输送系统包括输送线，第一支架，第二支架和护套。第一支架可以以放射状收缩构型布置在输送线的远侧区域的一部分周围，并且第二支架可以以放射状收缩构造布置在输送线的远侧区域的一部分周围。在一些情况下，第一支架和第二支架可以与第二支架远端的第一支架串联布置。护套可以可滑动地设置在输送线，第一支架和第二支架周围。鞘可以相对于输送线伸缩以展开第一支架和第二支架。在一些实施例中，第一支架和第二支架可以在容器中的目标位置处以重叠布置顺序地展开。

5. 发明申请

US20090105802A1 STENT DELIVERY CATHETER 审中-公开
标题翻译： STENT输送管
公开(公告)号：US20090105802A1
公开(公告)日：2009-04-23
申请号：US12337069
申请日：2008-12-17
申请人： William S. Henry , John E. Ortiz
发明人： William S. Henry , John E. Ortiz
IPC分类号： A61F2/06
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966
摘要： A self-expanding stent delivery assembly includes a shaft having a proximal end, a distal end, a distal region, a lumen, and a longitudinal axis. A retractable sheath having an outer surface, a proximal end and a distal end is co-axially disposed around the shaft distal region. A stent is disposed co-axially between the shaft and the retractable sheath. A tubular tapered tip is affixed to the retractable sheath distal end. The tubular tapered tip has an elongate region predisposed to fracturing. Methods of delivering a self-expanding stent are also described.
摘要翻译：自扩张支架输送组件包括具有近端，远端，远侧区域，内腔和纵向轴线的轴。具有外表面，近端和远端的可伸缩护套共轴地设置在轴远侧区域周围。支架同轴地设置在轴和可缩回护套之间。管状锥形尖端固定到可缩回护套远端。管状锥形尖端具有易于断裂的细长区域。还描述了递送自扩张支架的方法。

6. 发明授权

US08152841B2 Medical devices including metallic films 有权
标题翻译：医疗器械包括金属膜
公开(公告)号：US08152841B2
公开(公告)日：2012-04-10
申请号：US12766076
申请日：2010-04-23
申请人： Masoud Molaei , William S. Henry , Gregory D. Chin , Robert Z. Obara
发明人： Masoud Molaei , William S. Henry , Gregory D. Chin , Robert Z. Obara
IPC分类号： A61F2/82
CPC分类号： A61F2/90 , A61F2/07 , A61F2/856 , A61F2002/072 , A61F2002/075 , A61F2002/823 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2230/0054
摘要： Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.
摘要翻译：公开了医疗装置，例如内用假体，以及制造装置的方法。医疗装置可以包括由沉积的金属膜和一个或多个聚合物层形成的复合罩。聚合物层有助于内用假体的机械或生物学性质。

7. 发明申请

US20100204784A1 MEDICAL DEVICES INCLUDING METALLIC FILMS 有权
标题翻译：包括金属膜的医疗器械
公开(公告)号：US20100204784A1
公开(公告)日：2010-08-12
申请号：US12766076
申请日：2010-04-23
申请人： Masoud Molaei , William S. Henry , Gregory D. Chin , Robert Z. Obara
发明人： Masoud Molaei , William S. Henry , Gregory D. Chin , Robert Z. Obara
IPC分类号： A61F2/82
CPC分类号： A61F2/90 , A61F2/07 , A61F2/856 , A61F2002/072 , A61F2002/075 , A61F2002/823 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2230/0054
摘要： Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The medical device can include a composite cover formed of a deposited metallic film and one or more polymer layers. The polymer layers contribute to mechanical or biological properties of the endoprosthesis.
摘要翻译：公开了医疗装置，例如内用假体，以及制造装置的方法。医疗装置可以包括由沉积的金属膜和一个或多个聚合物层形成的复合罩。聚合物层有助于内用假体的机械或生物学性质。

8. 发明申请

US20090050718A1 Method for Micro-sizing Organic, Inorganic and Engineered Compounds 有权
标题翻译：微量化有机，无机和工程化合物的方法
公开(公告)号：US20090050718A1
公开(公告)日：2009-02-26
申请号：US12171176
申请日：2008-07-10
申请人： William S. Henry , Edwin B. Fay , Ronald R. Warnecke , Gary L. Palmer
发明人： William S. Henry , Edwin B. Fay , Ronald R. Warnecke , Gary L. Palmer
IPC分类号： B02C19/06
CPC分类号： B02C19/06 , A61K9/14 , A61K9/1682 , B02C19/186 , Y10S241/37
摘要： A method and system are provided herein for forming microparticles from plastic and elastomeric materials that cannot be reduced in size by conventional methods. The system includes a high-pressure liquid nitrogen energy source, a feeder for providing a preferred constant and uninterrupted feed to a mill, a preferred integral injection device to meter the feed into a chamber for milling and/or classification, and a preferred exhaust system for collection of the milled product.
摘要翻译：本文提供的方法和系统用于通过常规方法不能减小尺寸的塑料和弹性体材料形成微粒。该系统包括高压液氮能源，用于向研磨机提供优选的恒定和不间断进料的进料器，用于计量进入用于研磨和/或分级的室的进料的优选的一体式喷射装置，以及优选的排气系统用于收集碾磨产品。

9. 发明授权

US06331647B1 Process for the preparation of a purified acrylamido sulfonic acid monomer derivative 失效
标题翻译：制备纯化丙烯酰氨基磺酸单体衍生物的方法
公开(公告)号：US06331647B1
公开(公告)日：2001-12-18
申请号：US08355712
申请日：1994-12-14
申请人： Robert E. Quinn , W. Michael Burke , William S. Henry , Steven A. Goodlive
发明人： Robert E. Quinn , W. Michael Burke , William S. Henry , Steven A. Goodlive
IPC分类号： C07C30915
CPC分类号： C07C303/44 , C07C309/15
摘要： A process for the preparation of a purified monomer is disclosed which comprises the steps of reacting an impure monomer wherein R1 and R2 are independently hydrogen or alkyl groups containing from 1 to about 6 carbon atoms, with (B) a substantially aqueous solution of an oxide or hydroxide of the structure MO or MOH wherein M is a Group IA or Group IIA metal, or an amine of the structure NR3R4R5 wherein R3, R4 and R5 are independently hydrogen or alkyl, alkanol or alkoxy groups containing from 1 to about 12 carbon atoms, wherein the molar ratio of (A):(B) is from about 1:1-2 for Group IA metals, 2:1-2 for Group IIA metals or ratio of moles of (A) to nitrogens of (B) is from about 1:1-2 nitrogens to form a salt, wherein in order to prevent polymerization of (A), the purified monomer or both or prevent undesired side reactions, the reaction of (A) and (B) occurs at a temperature of between about −20 to 75° C. and at a pH between about 7 to about 12.5, and recovering a purified salt by crystallization in the presence of an oxygen bearing gas stream by subjecting the aqueous solution to changes in temperature and/or pressure and/or concentration.
摘要翻译：公开了一种制备纯化单体的方法，其包括使不纯的单体反应，其中R1和R2独立地为氢或含有1至约6个碳原子的烷基，（B）基本上为水溶液的氧化物或结构MO或MOH的氢氧化物，其中M为IA或IIA族金属，或NR3R4R5结构的胺，其中R3，R4和R5独立地为氢或含有1至约12个碳原子的烷基，链烷醇或烷氧基，其中（A）：（B）的摩尔比对于IA族金属为约1：1-2，对于IIA族金属为2：1-2，（B）的（A）与氮的摩尔比为约1：1-2个氮以形成盐，其中为了防止（A）的聚合，纯化的单体或两者的聚合或防止不期望的副反应，（A）和（B）的反应在约-20至75℃，pH为约7至约12.5，并通过哭泣回收纯化的盐通过使水溶液经受温度和/或压力和/或浓度的变化，在含氧气流的存在下失速。

10. 发明授权

US08083162B2 Method for micro-sizing organic, inorganic and engineered compounds 有权
标题翻译：微量化有机，无机和工程化合物的方法
公开(公告)号：US08083162B2
公开(公告)日：2011-12-27
申请号：US12171176
申请日：2008-07-10
申请人： William S. Henry , Edwin B. Fay , Ronald R. Warnecke , Gary L. Palmer
发明人： William S. Henry , Edwin B. Fay , Ronald R. Warnecke , Gary L. Palmer
IPC分类号： B02C19/06
CPC分类号： B02C19/06 , A61K9/14 , A61K9/1682 , B02C19/186 , Y10S241/37
摘要： A method and system are provided herein for forming microparticles from plastic and elastomeric materials that cannot be reduced in size by conventional methods. The system includes a high-pressure liquid nitrogen energy source, a feeder for providing a preferred constant and uninterrupted feed to a mill, a preferred integral injection device to meter the feed into a chamber for milling and/or classification, and a preferred exhaust system for collection of the milled product.
摘要翻译：本文提供的方法和系统用于通过常规方法不能减小尺寸的塑料和弹性体材料形成微粒。该系统包括高压液氮能源，用于向研磨机提供优选的恒定和不间断进料的进料器，用于计量进入用于研磨和/或分级的室的进料的优选的一体式喷射装置，以及优选的排气系统用于收集碾磨产品。

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