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1. 发明专利

GB691532A A heavy duty switch for the battery circuit of a vehicle internal combustion engine 未知
公开(公告)号：GB691532A
公开(公告)日：1953-05-13
申请号：GB735850
申请日：1950-03-23
申请人： ERNEST WILLIAM PARRISH
IPC分类号： B60R16/00
摘要： 691,532. Heavy-current switches; switch contacts. PARRISH, E. W. March 22,1951 [March 23,1950], No. 7358/50. Class 38(v) A switch intended for use in large motor vehicles comprises opposed pairs of laminated contacts 15 respectively bridged by contact studs 29 in an insulating disc 28 rotatable by a handle 27 on a shaft 26. The studs 29 are located in somewhat larger holes 38 in the disc 28 and have a peripheral groove 37 whereby they are retained by rivets 30 so as to be movable endwise as well as rotatable in the disc. The contacts 15 are fixed to the ends of insulating strips 10 which run in a groove in the insulating base 9 and extend across the latter. Terminal blocks 17 associated with the contacts 15 have elongated apertures for receiving the "in" and "out" conductors which are soldered therein, holes then being drilled through the blocks for fixing screws 18. The conductors enter part 3 of the casing through openings 6 and watertightness is ensured by rubber diaphragms placed thereover after the cables are in place. Cable entries not used are closed by covers 7 held by frames 8. Channel members 13 associated with each contact 15 slidably carry spring-loaded bolts 22 whose heads abut the rear of the respective contact 15 to ensure good contact-making.

2. 发明专利

GB592630A Improvements in limit control devices 未知
公开(公告)号：GB592630A
公开(公告)日：1947-09-24
申请号：GB629845
申请日：1945-03-13
申请人： ERNEST WILLIAM PARRISH
IPC分类号： B60P3/22 , G05G15/04
摘要： 592,630. Reciprocating pumps. PARRISH, E. W. March 13, 1945, No. 6298. [Class 102 (i)] [Also in Groups XXVI and XXXVII] A device for stopping a mechanism, such as an engine driven pump, when a prescribed limit in a reversible operation, such as filling a petrol tarik, is reached, comprises a pair of two-way switches 6, 18 so connected in the engine ignition or other circuit that either can open or close the. circuit independently of the other; the switch 6 being automatically operated, e.g., by a float in the tank, to break the circuit and stop the engine when the tank is full, while the switch 18 is subsequently manually operated to remake the circuit to permit the engine to be restarted and emptying to commence. Switch 6, which may be a float operated mercury switch, is returned to its original position automatically during the emptying operation. An additional switch overriding the two-way switches may be provided, arranged to return to its non- overriding position after a predetermined lapse of time.

3. 发明专利

GB178533A Improved signalling means for use on motor cars or vehicles 未知
公开(公告)号：GB178533A
公开(公告)日：1922-04-18
申请号：GB207221
申请日：1921-01-14
申请人： ERNEST WILLIAM PARRISH
IPC分类号： H01H21/26
摘要： 178,533. Parrish, E. W. Jan. 14, 1921. Road-traffic signals on vehicles.-In signalling apparatus for use on vehicles of the kind in which the circuits of lamps to indicate the direction of turning are initially closed by a switch and remain closed until the steering-wheel has returned to its central position, the initial completion of the circuit is by depression of a push 26 which forces down the armature 24 of a magnet 23 to maks contact at 25, 27. These contacts complete a circuit through the appropriate lamp and the magnet 23 in series so that the switch is held closed. Turning of the steering-wheel traverses a block 18 along a quick-pitched screw 17 to make. contact between blocks 13, 15, or 13, 16. This contact itself closes the lamp circuit and at the same time cuts out the magnet 23 so that when the steering-wheel moves the block 18 off either of the blocks 15, 16, the circuit of the lamp is broken. A separate lamp to indicate stopping is closed by contacts 35 on a disc 33 fixed on a rod 30 which slides against the action of a spring when the brake pedal 28 is depressed, contacts 35 being brought against fixed contacts 36.

4. 发明专利

GB201659A Improvements relating to the lamps used on motor road vehicles for signalling purposes 未知
公开(公告)号：GB201659A
公开(公告)日：1923-08-07
申请号：GB1288022
申请日：1922-05-06
申请人： ERNEST WILLIAM PARRISH
IPC分类号： B60Q1/26
摘要： 201,659. Parrish, E. W. May 6,1922. Signal and vehicle lamps.-Lamps for indicating turning are combined with the side lamps of the vehicle. The two lamps 6 have reflectors 2 back to back, and the signalling lamp illuminates a piece of coloured glass 4 bearing an indication.

5. 发明专利

GB969669A Improvements in or relating to electrical switch gear 未知
公开(公告)号：GB969669A
公开(公告)日：1964-09-16
申请号：GB1024062
申请日：1962-03-16
申请人： ERNEST WILLIAM PARRISH
IPC分类号： H01H9/00 , H01H21/02 , H01H21/12
摘要： 969,669. Mechanical switches, without quickaction. E. W. PARRISH. Jan. 23, 1963 [March 16, 1962], No. 10240/62. Heading H2B. An electric switch, preferably for isolating the battery from the electrical system of a vehicle carrying petrol &c., comprises at least two pairs of stationary contacts 1, 2, biased by springs 4 located in insulating pads 5 and a contact barrel 10 of insulating material with contact strips 12 on two faces. Initially the pairs of contacts 1, 2 are bridged by the contact strips 12, but on rotation of the barrel 10, the pairs of contacts 1, 2 and strips 12 are isolated. Terminals 7 of the contacts are aligned with holes 14 either in the base or sides of the casing. An earth testing contact 15 is provided for engagement with the contact 2 so that contact is broken when the barrel is rotated, thus indicating a fault by means of the vehicle's components. In another embodiment, Fig. 11 (not shown), the contact 15 is replaced by a forked blade contact movable by an insulating member, located between the switch contact and biasing spring, when the barrel is rotated. The barrel 10 may also be modified to have one or more contact studs extending through the barrel between the sides without the strips 12 so that the switch may be connected as a doublepole circuit breaker, Fig. 5 (not shown), may connect two batteries in parallel or series, Figs. 6, 7 (not shown), may be a reversing switch, Fig. 8 (not shown), or a change-over switch, Fig. 9 (not shown).

6. 发明专利

GB754471A Improvements in direction indicators and stop lights for motor vehicles 未知
公开(公告)号：GB754471A
公开(公告)日：1956-08-08
申请号：GB934154
申请日：1954-03-30
申请人： ERNEST WILLIAM PARRISH
IPC分类号： B60Q1/44
摘要： 754,471. Road-traffic signals on vehicles. PARRISH, E. W. March 30, 1955 [March 30, 1954], No. 9341/54. Class 118(2) A direction signalling system for vehicles of the flashing-light type comprises a three-position control switch 22 which connects the battery 26 to a selected one of movable contacts 7 or 8 when moved from its central off position. The battery is simultaneously connected to motor 2 which drives contacts 7 and 8 by means of a cam (Figs. 1 and 2, not shown) so that they alternate between contacts 10, 12 and 11, 13, respectively. The selected front and rear signalling lamps 16, 17 or 19, 20 are thereby flashed and the respective low consumption pilot lamp 18 or 21 lights in series with the unlit one of the pair of selected signalling lamps each time the other one flashes. The pilot lamp thus flashes at twice the frequency of a signalling lamps A threepoint switch 28 is operated and feeds the two rear lamps 16 and 19 steadily whenever the brake is applied. This also lights both pilot lamps 18 and 21 steadily. If a turn is signalled while braking the rear lamps 16, 19 light steadily and the selected front lamp 17 or 21 flashes. Thus the pilot lamp on the turn-side flashes at half normal frequency while the other pilot lamp remains steadily lit. The control switch and pilot lamps are preferably mounted together on the dashboard where they can be easily seen and reached. The switch 22 may be replaced by relays operated by an existing direction indicator switch.

7. 发明专利

GB287957A Improvements in electric switches for use on motor vehicles 未知
公开(公告)号：GB287957A
公开(公告)日：1928-03-26
申请号：GB3269026
申请日：1926-12-24
申请人： ERNEST WILLIAM PARRISH
IPC分类号： B60R16/00
摘要： 287,957. Parrish, E. W. Dec. 24, 1926. Switches, quick - action; contacts. - A snap - action double-pole switch for disconnecting the battery from the lighting circuit of a motor vehicle. is provided with an .extra contact or switching member fixed to the handle of the switch and adapted to earth the magneto when the switch handle is turned to break the battery circuit, before the battery circuit is actually broken. The snap-action mechanism may be of the kind shown in Figs. 2 and 3, in which rotation of the handle 4 in either direction rotates a member 14 which stresses a spring 13 which then tends to rotate a member 12 fixed to the movable contact carrying member 11. The latter rotation is prevented by the engagement of a projection 19, on a slide 16 mounted on the member 11, with one of four arc-shaped projections 15 on the base. until the slide and projection are sufficiently moved by the rotation of a pinion 20 driven by the handle whereupon the slide and member 11 and contacts 7, 8 rotate through 90‹ into or out of bridging engagement with the pairs of contacts 5, 6 which are arranged at different levels. In accordance with the invention, the switch has an additional contact 22, Figs. 6 and 7, fixed to its spindle 2 and thus to the handle 4. The contact takes the form of a .disc of phosphor bronze 22 with cut-away portions 23, which is adapted to engage a fixed contact 21. In modifications, the additional elements may comprise a cut-away insulating disc which passes between co-operating fixed contacts, or a disc of metal connected to a cut-away insulating disc may pass between the contacts.

8. 发明授权

US08572969B1 Method for increasing the efficiency of a steam engine and apparatus therefor 有权
标题翻译：提高蒸汽机效率的方法及其设备
公开(公告)号：US08572969B1
公开(公告)日：2013-11-05
申请号：US13374563
申请日：2011-12-31
申请人： William Parrish Horne
发明人： William Parrish Horne
IPC分类号： F01K13/00
CPC分类号： F01K7/00
摘要： A steam engine receives steam from a boiler which is heated by hot gas produced by a burner. The flue gas from the boiler is used to heat the body of the steam engine. The body of the steam engine has a plurality of passages which are shaped and dimensioned to receive and pass the flue gas, so that the flue gas heats the body, and thereby increases the power and efficiency of the steam engine.
摘要翻译：蒸汽发动机从由燃烧器产生的热气体加热的锅炉中接收蒸汽。来自锅炉的烟气用于加热蒸汽机的主体。蒸汽发动机的主体具有多个通道，其形状和尺寸适于接收和通过烟道气，使得烟道气加热身体，从而增加蒸汽机的功率和效率。

9. 发明申请

US20120219546A1 METHODS FOR TREATING CONDITIONS MEDIATED BY THE INFLAMMATORY CYTOKINE CASCADE USING GAPDH INHIBITORS 失效
标题翻译：使用GAPDH抑制剂治疗炎症细胞因子介导的病症治疗方法
公开(公告)号：US20120219546A1
公开(公告)日：2012-08-30
申请号：US13391465
申请日：2010-08-17
申请人： Kevin Tracey , William Parrish
发明人： Kevin Tracey , William Parrish
IPC分类号： A61K39/395 , A61P1/00 , A61P1/04 , A61P1/02 , A61P1/18 , A61P31/14 , A61P11/06 , A61P37/08 , A61P37/00 , A61P9/10 , A61P17/00 , A61P15/02 , A61P13/08 , A61P11/08 , A61P11/00 , A61P33/00 , A61P31/04 , A61P31/12 , A61P31/16 , A61P31/22 , A61P31/18 , A61P31/10 , A61P33/06 , A61P17/02 , A61P7/02 , A61P29/00 , A61P9/04 , A61P25/00 , A61P27/02 , A61P19/08 , A61P19/06 , A61P21/04 , A61P5/14 , A61P19/04 , A61P37/06 , C12Q1/32 , A61P31/00
CPC分类号： C07K16/40 , C07K2317/76
摘要： The present invention is directed to a method of treating a subject at risk for or having a condition mediated by an inflammatory cytokine cascade comprising administering to the subject an amount of a GAPDH inhibitor effective to treat the subject at risk for or having a condition mediated by an inflammatory cytokine cascade.
摘要翻译：本发明涉及一种治疗处于危险中或具有由炎性细胞因子级联介导的病症的受试者的方法，其包括向所述受试者施用一定量的有效治疗所述受试者处于或具有由炎性细胞因子级联。

10. 发明申请

US20130084310A1 COMPOSITIONS AND METHODS FOR PLATELET ENRICHED FIBRIN CONSTRUCTS 审中-公开
标题翻译：组合物和方法用于板材加强的纤维结构
公开(公告)号：US20130084310A1
公开(公告)日：2013-04-04
申请号：US13250086
申请日：2011-09-30
申请人： Mehmet Z. Sengun , William Parrish , Gregory R. Whittaker , Douglas A. Fifolt , Brooks J. Story
发明人： Mehmet Z. Sengun , William Parrish , Gregory R. Whittaker , Douglas A. Fifolt , Brooks J. Story
IPC分类号： A61K9/00 , A61P43/00 , B32B37/14 , A61K35/14
CPC分类号： A61K35/17 , A61K35/14 , A61K35/19 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1841 , A61K38/1866 , A61K38/1875 , A61K38/363 , A61K38/55 , A61L15/32 , A61L27/225 , A61L27/38 , A61L27/54 , A61L2300/414 , A61K2300/00
摘要： Compositions and methods are provided for tissue constructs that promote wound healing. The composition comprises a dimensionally stable fibrin construct for local administration to a wound site or region. In one embodiment, the fibrin construct is a wound healing composition, including components that promote wound healing, such as platelets, growth factors, white blood cells and fibrin clots. In another embodiment, the tissue treatment composition includes (i) aggregated fibrin, (ii) blood cells, and (iii) optionally, growth factors and/or other proteins.
摘要翻译：为促进伤口愈合的组织结构提供组合物和方法。组合物包含用于局部施用于伤口部位或区域的尺寸稳定的纤维蛋白构建体。在一个实施方案中，纤维蛋白构建体是伤口愈合组合物，包括促进伤口愈合的成分，例如血小板，生长因子，白细胞和纤维蛋白凝块。在另一个实施方案中，组织处理组合物包括（i）聚集的纤维蛋白，（ii）血细胞，和（iii）任选的生长因子和/或其它蛋白质。

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