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1. 发明申请

WO2012051454A2 PUMPING BLOOD 审中-公开
标题翻译：泵血
公开(公告)号：WO2012051454A2
公开(公告)日：2012-04-19
申请号：PCT/US2011/056217
申请日：2011-10-13
申请人： THORATEC CORPORATION , REICHENBACH, Steven, H. , LE BLANC, Pieter, W., C., J. , WOO, Yi-Ren , ELDRIDGE, David Gary
发明人： REICHENBACH, Steven, H. , LE BLANC, Pieter, W., C., J. , WOO, Yi-Ren , ELDRIDGE, David Gary
IPC分类号： A61M1/10
CPC分类号： A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/1025 , A61M1/1031 , A61M1/12 , A61M1/122 , A61M1/125 , A61M1/127 , A61M25/005 , A61M2205/04
摘要： A blood pump includes a rotor having a flared portion downstream proximate a downstream bearing that supports the rotor. The flared portion of the rotor includes a width greater than a width of an upstream portion of the rotor. A blood pump also includes a housing having an internal wall with a flared portion downstream of a motor stator and proximate a transverse outlet.
摘要翻译：血泵包括转子，该转子具有在靠近支撑转子的下游轴承的下游处的扩口部分。转子的张开部分的宽度大于转子的上游部分的宽度。血泵还包括具有内壁的壳体，该内壁具有位于马达定子下游并且靠近横向出口的张开部分。

2. 发明申请

WO2009045332A3 PROSTHETIC HEART VALVES WITH FLEXIBLE LEAFLETS AND LEAFLET EDGE CLAMPING 审中-公开
标题翻译：具有灵活的叶片和叶片边缘夹钳的前置心脏瓣膜
公开(公告)号：WO2009045332A3
公开(公告)日：2009-06-11
申请号：PCT/US2008011178
申请日：2008-09-26
申请人： ST JUDE MEDICAL , LI XUEMEI , WOO YI-REN
发明人： LI XUEMEI , WOO YI-REN
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2415 , A61F2220/005 , A61F2220/0075
摘要： A prosthetic heart valve includes an annular stent structure having a plurality of annularly spaced stent post regions, a plurality of leaflets that extend radially inward from the stent structure and that include radially outer portions that lie against a radially outer surface of the stent structure, and a clamping structure that is radially outside the other components and that clamps the radially outer portions of the leaflets against the radially outer surface of the stent structures to secure the leaflets to the stent structure. The above-described structural arrangement applies to the stent post regions as well as to other portions of the stent structure.
摘要翻译：假体心脏瓣膜包括环形支架结构，其具有多个环形间隔支架柱区域，多个叶片，其从支架结构径向向内延伸并且包括位于支架结构的径向外表面的径向外部部分，以及夹紧结构，其径向地位于其他部件外部，并将小叶的径向外部部分压靠在支架结构的径向外表面上，以将小叶固定到支架结构。上述结构布置适用于支架支柱区域以及支架结构的其它部分。

3. 发明申请

WO2008063537A2 PROSTHETIC HEART VALVE STRUCTURES AND RELATED METHODS 审中-公开
标题翻译：先天性心脏瓣膜结构及相关方法
公开(公告)号：WO2008063537A2
公开(公告)日：2008-05-29
申请号：PCT/US2007/023997
申请日：2007-11-15
申请人： ST. JUDE MEDICAL, INC. , WOO, Yi-ren
发明人： WOO, Yi-ren
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2442 , A61F2/2457
摘要： A prosthetic heart valve includes a valve core and a mounting retainer that extends radially out from the core to an outer perimeter portion. The outer perimeter portion has a different shape than a perimeter of the valve core when both perimeters are viewed along an axis that will be the axis of blood flow through the valve core when the prosthetic heart valve is in use in a patient. The outer perimeter portion is used to mount the valve to another structure such as a native valve annulus in a valve replacement procedure. The mounting retainer bridges the gap(s) between the valve core and the outer perimeter portion, and may also provide attachment sites for other native tissue structures (like chordae tendonae), which attachment sites can be at or at least closer to original (native) attachment sites for those tissue structures.
摘要翻译：假体心脏瓣膜包括阀芯和从芯部径向延伸到外周部分的安装保持器。当在假体心脏瓣膜在患者中使用时，外周边部分具有与阀芯的周边不同的形状，当沿着轴线观察两个周边时，该轴线将是通过阀芯的血液流动轴线。外部周边部分用于将阀安装到另一种结构，例如瓣膜置换过程中的天然瓣膜环。安装保持器桥接阀芯和外周边部分之间的间隙，并且还可以为其他天然组织结构（如腱索腱）提供附着位点，该附着位点可处于或至少更接近原始（本地）这些组织结构的附着位点。

4. 发明申请

WO2012051454A3 PUMPING BLOOD 审中-公开
标题翻译：泵血
公开(公告)号：WO2012051454A3
公开(公告)日：2012-07-19
申请号：PCT/US2011056217
申请日：2011-10-13
申请人： THORATEC CORP , REICHENBACH STEVEN H , LE BLANC PIETER W C J , WOO YI-REN , ELDRIDGE DAVID GARY
发明人： REICHENBACH STEVEN H , LE BLANC PIETER W C J , WOO YI-REN , ELDRIDGE DAVID GARY
IPC分类号： A61M1/10
CPC分类号： A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/1025 , A61M1/1031 , A61M1/12 , A61M1/122 , A61M1/125 , A61M1/127 , A61M25/005 , A61M2205/04
摘要： A blood pump includes a rotor having a flared portion downstream proximate a downstream bearing that supports the rotor. The flared portion of the rotor includes a width greater than a width of an upstream portion of the rotor. A blood pump also includes a housing having an internal wall with a flared portion downstream of a motor stator and proximate a transverse outlet.
摘要翻译：血泵包括具有支撑转子的下游轴承附近的扩张部分的转子。转子的扩口部分的宽度大于转子上游部分的宽度。血液泵还包括具有内壁的外壳，其具有位于马达定子下游并且靠近横向出口的扩口部分。

5. 发明申请

WO2008112243A1 PROSTHETIC HEART VALVES WITH FLEXIBLE LEAFLETS 审中-公开
标题翻译：具有柔韧性叶片的前置心脏瓣膜
公开(公告)号：WO2008112243A1
公开(公告)日：2008-09-18
申请号：PCT/US2008/003252
申请日：2008-03-12
申请人： ST. JUDE MEDICAL, INC. , LI, Xuemei , WOO, Yi-ren
发明人： LI, Xuemei , WOO, Yi-ren
IPC分类号： A61F2/24
CPC分类号： A61F2/2415
摘要： A prosthetic heart valve (10) of the type that includes a hollow annular stent (20) and a plurality of flexible leaflets (30a, 30b, 30c) that are attached to the stent. One or more fixture structures (i.e. clips (10Oa)) are used to attach the leaflets to the stent so that sutures do not have to be used for that purpose. The fixture structures preferably extend annularly at least substantially all the way around the valve. Surfaces of the fixture structures that can come into contact with portions of the leaflets that move during use of the valve can be shaped to help beneficially shape those leaflet portions during their movements.
摘要翻译：一种假体心脏瓣膜（10），其包括中空的环形支架（20）和附接到支架的多个柔性小叶（30a，30b，30c）。使用一个或多个夹具结构（即夹子（100A））将传单附接到支架上，使得缝合线不必用于该目的。固定结构优选地至少基本上围绕阀全部地环向延伸。能够与使用阀门期间移动的小叶的部分接触的夹具结构的表面可以被成形为有助于在移动过程中有利地塑造这些叶片部分。

6. 发明申请

WO2008063537A3 PROSTHETIC HEART VALVE STRUCTURES AND RELATED METHODS 审中-公开
标题翻译：先天性心脏瓣膜结构及相关方法
公开(公告)号：WO2008063537A3
公开(公告)日：2008-08-14
申请号：PCT/US2007023997
申请日：2007-11-15
申请人： ST JUDE MEDICAL , WOO YI-REN
发明人： WOO YI-REN
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2409 , A61F2/2442 , A61F2/2457
摘要： A prosthetic heart valve includes a valve core (20) and a mounting retainer (39) that extends radially out from the core to an outer perimeter portion (40). The outer perimeter portion has a different shape than a perimeter of the valve core when both perimeters are viewed along an axis that will be the axis of blood flow through the valve core when the prosthetic heart valve is in use in a patient. The outer perimeter portion is used to mount the valve to another structure such as a native valve annulus in a valve replacement procedure. The mounting retainer bridges the gap(s) between the valve core and the outer perimeter portion, and may also provide attachment sites for other native tissue structures (like chordae tendonae), which attachment sites can be at or at least closer to original (native) attachment sites for those tissue structures.
摘要翻译：假体心脏瓣膜包括阀芯（20）和从芯部径向向外延伸到外周边部分（40）的安装保持器（39）。当在假体心脏瓣膜在患者中使用时，外周边部分具有与阀芯的周边不同的形状，当沿着轴线观察两个周边时，该轴线将是通过阀芯的血液流动轴线。外部周边部分用于将阀安装到另一种结构，例如瓣膜置换过程中的天然瓣膜环。安装保持器桥接阀芯和外周边部分之间的间隙，并且还可以为其他天然组织结构（如腱索腱）提供附着位点，该附着位点可处于或至少更接近原始（本地）这些组织结构的附着位点。

7. 发明申请

WO2013056131A1 PUMP AND METHOD FOR MIXED FLOW BLOOD PUMPING 审中-公开
标题翻译：混合流动血液泵浦的泵和方法
公开(公告)号：WO2013056131A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/060071
申请日：2012-10-12
申请人： REICHENBACH, Steven H. , BLANC, Pieter W.C.J. , WOO, Yi-Ren , ELDRIDGE, David Gary , BRIANA, Stephen G. , HODGES, William V. , PETERSEN, Ethan , ANDRIOLA, Peter
发明人： REICHENBACH, Steven H. , BLANC, Pieter W.C.J. , WOO, Yi-Ren , ELDRIDGE, David Gary , BRIANA, Stephen G. , HODGES, William V. , PETERSEN, Ethan , ANDRIOLA, Peter
IPC分类号： A61M1/12
CPC分类号： A61M1/122 , A61F2/06 , A61F2/07 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/1031 , A61M1/1036 , A61M1/1086 , A61M1/127 , A61M2205/04 , A61M2205/103 , A61M2205/702 , F04D13/06 , F04D13/0633 , F04D13/064 , F04D15/0066 , F04D15/0077 , F04D17/08 , F04D29/046 , F04D29/0467 , F04D29/22 , F04D29/242 , Y10T29/49236
摘要： A blood pump includes a hub having an axis of rotation and a generally cylindrical shape. The hub has an upstream end region, a central region, and a downstream end region, and the hub includes a magnetic material. Blades that are disposed on the downstream end region of the hub extend downstream of the hub.
摘要翻译：血泵包括具有旋转轴线和大致圆柱形形状的轮毂。轮毂具有上游端区域，中心区域和下游端区域，并且轮毂包括磁性材料。设置在轮毂的下游端区域上的刀片延伸到轮毂的下游。

8. 发明申请

WO2012024567A1 ASSEMBLY AND METHOD FOR STABILIZING A PERCUTANEOUS CABLE 审中-公开
标题翻译：用于稳定电缆的组装和方法
公开(公告)号：WO2012024567A1
公开(公告)日：2012-02-23
申请号：PCT/US2011/048381
申请日：2011-08-19
申请人： THORATEC CORPORATION , WOO, Yi-Ren , REICHENBACH, Steven, H. , BRIANA, Stephen , WALSH, Kelly , BOURQUE, Kevin
发明人： WOO, Yi-Ren , REICHENBACH, Steven, H. , BRIANA, Stephen , WALSH, Kelly , BOURQUE, Kevin
IPC分类号： A61M39/02
CPC分类号： A61M39/0247 , A61M39/0208 , A61M2039/0223 , A61M2039/0261
摘要： A percutaneous cable is attached to a mechanical cardiac pump and is passed through the skin. Sutures can be used to stabilize the cable against movement to prevent disturbing tissue surrounding cable and thereby reduce the incidence of infection. A funnel-shaped tubular device can be used where the cable exits the skin to allow the cable to flex below or near the skin surface as may be desired to accommodate physical activity of a patient. An anchor can be attached to the cable and implanted below the skin surface to stabilize the cable against movement. The anchor can include any one or a combination of a flat mesh material, a bundle of ultrafine filaments, and a barbed filament.
摘要翻译：经皮电缆连接到机械心脏泵并通过皮肤。可以使用缝合线来稳定电缆以防止运动，以防止扰乱组织周围的电缆，从而减少感染的发生。可以使用漏斗形管状装置，其中电缆离开皮肤，以允许电缆弯曲到皮肤表面下方或附近，以满足患者身体活动的需要。锚固件可以附接到电缆并且植入皮肤表面以使电缆稳定以防止运动。锚固件可以包括扁平网状材料，超细丝束和带刺的细丝中的任何一种或组合。

9. 发明申请

WO2008133852A1 TECHNIQUES FOR ATTACHING FLEXIBLE LEAFLETS OF PROSTHETIC HEART VALVES TO SUPPORTING STRUCTURES 审中-公开
标题翻译：连接灵活的心脏瓣膜支持结构的技术
公开(公告)号：WO2008133852A1
公开(公告)日：2008-11-06
申请号：PCT/US2008/005045
申请日：2008-04-18
申请人： ST. JUDE MEDICAL, INC. , LI, XueMei , WOO, Yi-Ren
发明人： LI, XueMei , WOO, Yi-Ren
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409
摘要： A prosthetic heart valve has an annular valve-perimeter-shape-defining structure having a radially outer surface. A clip structure is provided on the outer surface. This clip structure is used to attach flexible valve leaflets to the shape-defining structure. One or more retainer members may be used to help hold the leaflets in the clip structure.
摘要翻译：假体心脏瓣膜具有具有径向外表面的环形阀周边形状限定结构。夹子结构设置在外表面上。该夹子结构用于将柔性瓣叶附接到形状限定结构。可以使用一个或多个保持器构件来帮助将传单保持在夹子结构中。

10. 发明申请

WO2008042093A3 PROSTHETIC HEART VALVES 审中-公开
标题翻译：先天性心脏瓣膜
公开(公告)号：WO2008042093A3
公开(公告)日：2008-05-29
申请号：PCT/US2007019900
申请日：2007-09-11
申请人： ST JUDE MEDICAL , WOO YI-REN
发明人： WOO YI-REN
IPC分类号： A61F2/24 , A61L27/52
CPC分类号： A61F2/2409 , A61F2/2412 , A61L27/507 , A61L27/52 , A61L27/54 , A61L2300/42
摘要： A prosthetic heart valve includes a hydrogel material in its sewing cuff. The hydrogel material may be accompanied by an anticoagulant. If the hydrogel (and/or any included anticoagulant) might react with a packaging solution in which the valve is stored after inclusion of the hydrogel (and any anticoagulant), the hydrogel (and any anticoagulant) may be included in a protective but deliberately frangible pouch in the sewing cuff. After the valve is out of the packaging solution, the pouch can be broken to render the hydrogel (and any coagulant) effective following implantation of the valve in a patient.
摘要翻译：假体心脏瓣膜包括其缝合袖口中的水凝胶材料。水凝胶材料可以伴随有抗凝剂。如果水凝胶（和/或任何包含的抗凝血剂）可能在包含水凝胶（和任何抗凝血剂）之后与其中储存阀的包装溶液发生反应，则可将水凝胶（和任何抗凝血剂）包含在保护性但故意易碎的袋缝在袖口。在阀门脱离包装溶液之后，袋子可以被破坏，使得在将患者植入瓣膜之后使水凝胶（和任何凝结剂）有效。

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