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    • 4. 发明申请
    • TORSIONALLY FLEXIBLE SEALED DRIVE
    • 扭转弹性密封驱动
    • WO2008144089A1
    • 2008-11-27
    • PCT/US2008/054653
    • 2008-02-22
    • NEW BRUNSWICK SCIENTIFIC COMPANY, INC.WATKINS, JeffYAO, Simin
    • WATKINS, JeffYAO, Simin
    • C12M1/12
    • C12M23/26B01F7/00675B01F11/0088B01F15/00831B01F15/0085C12M27/08
    • A simple, robust and low-cost torsionally flexible, sealed drive that allows external drives to provide agitation within a container. A torsionally flexible tube is sealed to a torsionally rigid portion of a container. A second end of the tube is sealed to a driven element within the container. The driven element is coupled to a drive- shaft that is partly contained within the tube. Motion of the protruding end of the drive shaft imparts a corresponding motion to the driven element, while maintaining a water-tight seal between container and drive-shaft. One useful motion is a rotary oscillation. A stepper motor may operate via such a drive to impart a rotary oscillation to an impellor in a bioreactor, or mixing container, suitable for agitating a cell culture in a nutrient medium or hydrating a powdered media in water. The drive is suited to use in disposable bioreactors and mixers.
    • 一种简单,坚固和低成本的扭转灵活的密封驱动器,允许外部驱动器在容器内提供搅动。 扭转柔性管被密封到容器的扭转刚性部分。 管的第二端被密封到容器内的从动元件。 被驱动元件联接到部分地包含在管内的驱动轴。 驱动轴的突出端的运动给驱动元件施加相应的运动,同时保持容器和驱动轴之间的水密密封。 一个有用的运动是旋转振荡。 步进马达可以经由这样的驱动器操作,以将旋转振荡给予生物反应器或混合容器中的叶轮,该混合容器适于搅拌营养培养基中的细胞培养物或将粉末状介质水合在水中。 该驱动器适用于一次性生物反应器和混合器。