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1. 发明授权

EP2889321B1 SURFACE CONTROL ADDITIVE FOR RADIATION CURING SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 有权
标题翻译：辐射固化系统的表面控制添加剂及其制备方法和应用
公开(公告)号：EP2889321B1
公开(公告)日：2017-05-31
申请号：EP12883275.5
申请日：2012-10-08
申请人： Wang, Zhijun , Afcona Chemicals (Haimen)
发明人： Wang, Zhijun
IPC分类号： C08G77/46 , C09D7/12 , C09D11/00 , G03F7/00
CPC分类号： C09D11/107 , C08G77/20 , C08G77/46 , C09D11/101 , G03F7/0048 , G03F7/0752
摘要： The present invention is related to a surface control additive for a radiation curing system, the method for its preparation as well as its application. The surface control additive has the following structure: wherein A is wherein m is an integer from 0 to 400, n is an integer from 1 to 500, x is an integer from 0 to 800, p is an integer from 0 to 600, q is an integer from 1 to 800, R 4 and R 5 are H or CH 3 respectively, R 6 is H or a linear or a branched alkyl group containing 1-18 carbon atoms or an acyl group containing 2-5 carbon atoms. The surface control additive of the present invention is applied to radiation curing (UV/EB) paint and inks, enables the coatings to maintain non-adhesive and smooth for a long time, and minimizes transferable precipitates from a cured film. In addition, by using different combinations of EO and PO, the surface control additive of the present invention can adapt to a free selection from high-polarity aquosity to a low-polarity aliphatic hydrocarbon solvent system.
摘要翻译：本发明涉及用于辐射固化体系的表面控制添加剂，其制备方法及其应用。表面控制添加剂具有以下结构：其中A是其中m是0至400的整数，n是1至500的整数，x是0至800的整数，p是0至600的整数，q 是1至800的整数，R 4和R 5分别是H或CH 3，R 6是H或含有1-18个碳原子的直链或支链烷基或含有2-5个碳原子的酰基。本发明的表面控制添加剂被应用于辐射固化（UV / EB）油漆和油墨，使得涂层能够长时间保持非粘合性和平滑性，并且使固化膜中可转移的沉淀物最小化。另外，通过使用EO和PO的不同组合，本发明的表面控制添加剂能够适应从高极性含水率向低极性脂肪烃溶剂系统的自由选择。

2. 发明公开

EP2889321A1 SURFACE CONTROL ADDITIVE FOR RADIATION CURING SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 有权
标题翻译： OBERFLÄCHENKONTROLLZUSATZFÜRSTRAHLUNGSHÄRTUNGSSYSTEM，HERSTELLUNGSVERFAHRENDAFÜRUND ANWENDUNG DAVON
公开(公告)号：EP2889321A1
公开(公告)日：2015-07-01
申请号：EP12883275.5
申请日：2012-10-08
申请人： Wang, Zhijun , Afcona Chemicals (Haimen)
发明人： Wang, Zhijun , Afcona Chemicals (Haimen)
IPC分类号： C08G77/46 , C09D7/12 , C09D11/00
CPC分类号： C09D11/107 , C08G77/20 , C08G77/46 , C09D11/101 , G03F7/0048 , G03F7/0752
摘要： The present invention is related to a surface control additive for a radiation curing system, the method for its preparation as well as its application. The surface control additive has the following structure:

wherein A is

wherein m is an integer from 0 to 400, n is an integer from 1 to 500, x is an integer from 0 to 800, p is an integer from 0 to 600, q is an integer from 1 to 800, R 4 and R 5 are H or CH 3 respectively, R 6 is H or a linear or a branched alkyl group containing 1-18 carbon atoms or an acyl group containing 2-5 carbon atoms. The surface control additive of the present invention is applied to radiation curing (UV/EB) paint and inks, enables the coatings to maintain non-adhesive and smooth for a long time, and minimizes transferable precipitates from a cured film. In addition, by using different combinations of EO and PO, the surface control additive of the present invention can adapt to a free selection from high-polarity aquosity to a low-polarity aliphatic hydrocarbon solvent system.
摘要翻译：本发明涉及一种用于辐射固化系统的表面控制添加剂，其制备方法及其应用。表面控制添加剂具有以下结构：其中A是0至400的整数，n是1至500的整数，x是0至800的整数，p是0至600的整数，q 是1〜800的整数，R 4和R 5分别为H或CH 3，R 6为H或含有1-18个碳原子的直链或支链烷基或含有2-5个碳原子的酰基。本发明的表面处理添加剂适用于辐射固化（UV / EB）涂料和油墨，使得涂料能够长时间保持非粘合和光滑，并使固化膜的可转移沉淀物最小化。此外，通过使用EO和PO的不同组合，本发明的表面处理添加剂可以适应从高极性水性到低极性脂族烃溶剂体系的自由选择。

3. 发明公开

EP2839873A1 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF 有权转让
标题翻译：聚氨酯分散剂及其制备方法
公开(公告)号：EP2839873A1
公开(公告)日：2015-02-25
申请号：EP12874369.7
申请日：2012-10-08
申请人： Wang, Zhijun
发明人： Wang, Zhijun
IPC分类号： B01F17/52 , C08G18/80 , C08G18/79 , C08G18/38 , C09D7/12 , C09D11/00
CPC分类号： C08G18/283 , B01F17/005 , C08G18/284 , C08G18/285 , C08G18/2865 , C08G18/2875 , C08G18/4277 , C08G18/4833 , C08G18/7887 , C08G18/79 , C08G18/792 , C08G18/795 , C09D5/4461 , C09D5/4488 , C09D7/40 , C09D11/037 , C09D11/102 , C09D17/003 , C09D17/004
摘要： The present invention is related to a polyurethane dispersant and a preparation method thereof. The polyurethane dispersant is terminated by a nitrogen-containing heterocyclic compound during synthesis. The nitrogen-containing heterocyclic compound is prepared by subjecting anhydride and a compound containing a primary amine and a secondary amine or a hydroxyl or mercapto group to dehydration condensation. The condensed product is the nitrogen-containing heterocyclic compound, containing a reactive hydrogen. The structural formula of the compound containing the primary amine and the secondary amine or hydroxyl or mercapto group is shown as follows:

wherein n=1 to 5, and preferably 2 to 4, R 1 and R 2 are respectively alkyls containing 1 to 8 carbons, R 1 and R 2 are independent of each other or connected by a chemical bond to form one or more saturated or unsaturated 4-member to 8-member rings, and X represents N, O, or S.
摘要翻译：本发明涉及一种聚氨酯分散剂及其制备方法。合成过程中聚氨酯分散剂被含氮杂环化合物封端。含氮杂环化合物通过使酸酐和含有伯胺和仲胺或羟基或巯基的化合物脱水缩合来制备。缩合产物是含有活性氢的含氮杂环化合物。含有伯胺和仲胺或羟基或巯基的化合物的结构式如下所示：其中n = 1至5，优选2至4，R 1和R 2分别为含有1至8个碳的烷基，R 1 和R2彼此独立或通过化学键连接形成一个或多个饱和或不饱和的4元至8元环，并且X代表N，O或S.

4. 发明公开

EP2839873A4 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF 有权转让
标题翻译：聚氨酯取代剂及其制造方法
公开(公告)号：EP2839873A4
公开(公告)日：2016-02-17
申请号：EP12874369
申请日：2012-10-08
申请人： WANG ZHIJUN , AFCONA CHEMICALS HAIMEN CO LTD
发明人： WANG ZHIJUN
IPC分类号： B01F17/52 , C08G18/38 , C08G18/79 , C08G18/80 , C09D7/12 , C09D11/00
CPC分类号： C08G18/283 , B01F17/005 , C08G18/284 , C08G18/285 , C08G18/2865 , C08G18/2875 , C08G18/4277 , C08G18/4833 , C08G18/7887 , C08G18/79 , C08G18/792 , C08G18/795 , C09D5/4461 , C09D5/4488 , C09D7/40 , C09D11/037 , C09D11/102 , C09D17/003 , C09D17/004
摘要： The present invention is related to a polyurethane dispersant and a preparation method thereof. The polyurethane dispersant is terminated by a nitrogen-containing heterocyclic compound during synthesis. The nitrogen-containing heterocyclic compound is prepared by subjecting anhydride and a compound containing a primary amine and a secondary amine or a hydroxyl or mercapto group to dehydration condensation. The condensed product is the nitrogen-containing heterocyclic compound, containing a reactive hydrogen. The structural formula of the compound containing the primary amine and the secondary amine or hydroxyl or mercapto group is shown as follows: wherein n=1 to 5, and preferably 2 to 4, R 1 and R 2 are respectively alkyls containing 1 to 8 carbons, R 1 and R 2 are independent of each other or connected by a chemical bond to form one or more saturated or unsaturated 4-member to 8-member rings, and X represents N, O, or S.
摘要翻译：本发明涉及一种聚氨酯分散剂及其制备方法。在合成过程中，聚氨酯分散剂被含氮杂环化合物封端。含氮杂环化合物通过使酸酐和含有伯胺和仲胺或羟基或巯基的化合物脱水缩合而制备。缩合产物是含有反应性氢的含氮杂环化合物。包含伯胺和仲胺或羟基或巯基的化合物的结构式如下所示：其中n = 1至5，优选2至4，R 1和R 2分别为含有1至8个碳的烷基，R 1和R 2彼此独立或通过化学键连接以形成一个或多个饱和或不饱和的4元件至8元环，X代表N，O或S.

5. 发明公开

EP2889321A4 SURFACE CONTROL ADDITIVE FOR RADIATION CURING SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 有权
标题翻译：用于辐射固化系统的表面控制补充剂，制造方法和应用
公开(公告)号：EP2889321A4
公开(公告)日：2015-10-14
申请号：EP12883275
申请日：2012-10-08
申请人： WANG ZHIJUN , AFCONA CHEMICALS HAIMEN
发明人： WANG ZHIJUN , AFCONA CHEMICALS HAIMEN
IPC分类号： C08G77/46 , C09D7/12 , C09D11/00 , C09D11/03 , G03F7/00
CPC分类号： C09D11/107 , C08G77/20 , C08G77/46 , C09D11/101 , G03F7/0048 , G03F7/0752
摘要： The present invention is related to a surface control additive for a radiation curing system, the method for its preparation as well as its application. The surface control additive has the following structure: wherein A is wherein m is an integer from 0 to 400, n is an integer from 1 to 500, x is an integer from 0 to 800, p is an integer from 0 to 600, q is an integer from 1 to 800, R 4 and R 5 are H or CH 3 respectively, R 6 is H or a linear or a branched alkyl group containing 1-18 carbon atoms or an acyl group containing 2-5 carbon atoms. The surface control additive of the present invention is applied to radiation curing (UV/EB) paint and inks, enables the coatings to maintain non-adhesive and smooth for a long time, and minimizes transferable precipitates from a cured film. In addition, by using different combinations of EO and PO, the surface control additive of the present invention can adapt to a free selection from high-polarity aquosity to a low-polarity aliphatic hydrocarbon solvent system.

6. 发明授权

EP2839873B1 POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF 有权转让
标题翻译：聚氨酯分散剂及其制备方法
公开(公告)号：EP2839873B1
公开(公告)日：2017-01-04
申请号：EP12874369.7
申请日：2012-10-08
申请人： Wang, Zhijun , AFCONA Chemicals (Haimen) Co., Ltd.
发明人： Wang, Zhijun
IPC分类号： B01F17/52 , C08G18/80 , C08G18/79 , C08G18/38 , C09D7/12 , C09D11/00
CPC分类号： C08G18/283 , B01F17/005 , C08G18/284 , C08G18/285 , C08G18/2865 , C08G18/2875 , C08G18/4277 , C08G18/4833 , C08G18/7887 , C08G18/79 , C08G18/792 , C08G18/795 , C09D5/4461 , C09D5/4488 , C09D7/40 , C09D11/037 , C09D11/102 , C09D17/003 , C09D17/004
摘要： The present invention is related to a polyurethane dispersant and a preparation method thereof. The polyurethane dispersant is terminated by a nitrogen-containing heterocyclic compound during synthesis. The nitrogen-containing heterocyclic compound is prepared by subjecting anhydride and a compound containing a primary amine and a secondary amine or a hydroxyl or mercapto group to dehydration condensation. The condensed product is the nitrogen-containing heterocyclic compound, containing a reactive hydrogen. The structural formula of the compound containing the primary amine and the secondary amine or hydroxyl or mercapto group is shown as follows: wherein n=1 to 5, and preferably 2 to 4, R 1 and R 2 are respectively alkyls containing 1 to 8 carbons, R 1 and R 2 are independent of each other or connected by a chemical bond to form one or more saturated or unsaturated 4-member to 8-member rings, and X represents N, O, or S.

7. 发明申请

WO2011109551A3 COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM 审中-公开
公开(公告)号：WO2011109551A3
公开(公告)日：2012-01-19
申请号：PCT/US2011026916
申请日：2011-03-02
申请人： CALCIMEDICA INC , VELICELEBI GONUL , STAUDERMAN KENNETH A , WHITTEN JEFFREY P , CAO JIANGUO , WANG ZHIJUN , ROGERS EVAN , DYCK BRIAN , GREY JONATHAN
发明人： VELICELEBI GONUL , STAUDERMAN KENNETH A , WHITTEN JEFFREY P , CAO JIANGUO , WANG ZHIJUN , ROGERS EVAN , DYCK BRIAN , GREY JONATHAN
IPC分类号： C07D471/04 , A61K31/428 , A61K31/437 , A61P19/02 , A61P37/00 , C07D333/38 , C07D417/12
CPC分类号： C07D409/12 , C07D333/38 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04
摘要： Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.

8. 发明申请

WO2011139489A2 COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM 审中-公开
标题翻译：调节细胞内钙的化合物
公开(公告)号：WO2011139489A2
公开(公告)日：2011-11-10
申请号：PCT/US2011/031992
申请日：2011-04-11
申请人： CALCIMEDICA INC. , WHITTEN, Jeffrey, P. , PEI, Yazhong , CAO, Jianguo , WANG, Zhijun , ROGERS, Evan , DYCK, Brian , GREY, Jonathan
发明人： WHITTEN, Jeffrey, P. , PEI, Yazhong , CAO, Jianguo , WANG, Zhijun , ROGERS, Evan , DYCK, Brian , GREY, Jonathan
IPC分类号： C07D405/04 , C07D405/14 , C07D213/81 , C07D213/72 , A61K31/443 , A61K31/44 , A61P29/00
CPC分类号： C07D213/74 , C07D213/75 , C07D241/20 , C07D401/04 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D493/10 , C07D495/04
摘要： Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store- operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
摘要翻译：本文描述了含有这种化合物的化合物和药物组合物，其调节储存操作的钙（SOC）通道的活性。本文还描述了使用这种SOC通道调节剂单独和与其它化合物组合用于治疗将受益于SOC通道活性抑制的疾病或病症的方法。

9. 发明申请

WO2012170951A2 COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM 审中-公开
公开(公告)号：WO2012170951A2
公开(公告)日：2012-12-13
申请号：PCT/US2012/041752
申请日：2012-06-08
申请人： CALCIMEDICA, INC. , WHITTEN, Jeffrey P. , GREY, Jonathan , CAO, Jianguo , WANG, Zhijun , ROGERS, Evan
发明人： WHITTEN, Jeffrey P. , GREY, Jonathan , CAO, Jianguo , WANG, Zhijun , ROGERS, Evan
CPC分类号： C07D277/42 , C07D263/48 , C07D277/54 , C07D409/04 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/10 , C07D417/12 , C07D417/14
摘要： Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.

10. 发明申请

WO2012040511A3 COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM 审中-公开
公开(公告)号：WO2012040511A3
公开(公告)日：2012-03-29
申请号：PCT/US2011/052834
申请日：2011-09-22
申请人： CALCIMEDICA, INC. , CAO, Jianguo , WHITTEN, Jeffrey, P. , PEI, Yazhong , WANG, Zhijun , ROGERS, Evan , GREY, Jonathan
发明人： CAO, Jianguo , WHITTEN, Jeffrey, P. , PEI, Yazhong , WANG, Zhijun , ROGERS, Evan , GREY, Jonathan
IPC分类号： C07D421/04 , C07D421/12 , C07D421/14 , A61K31/095 , A61P29/00 , A61P9/00
摘要： Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store- operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.

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