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1. 发明授权

US09995718B1 Chemical and biomedical nanosensors 有权
公开(公告)号：US09995718B1
公开(公告)日：2018-06-12
申请号：US14824311
申请日：2015-08-12
申请人： Vlad Joseph Novotny
发明人： Vlad Joseph Novotny
IPC分类号： G01N29/036 , G01N29/24 , G01N29/02
CPC分类号： G01N29/2437 , B82Y15/00 , G01N29/022 , G01N2291/014 , G01N2291/02416 , G01N2291/02466 , G01N2291/0255 , G01N2291/0256 , G01N2291/0257
摘要： The electrostatic sensors of bridge or cantilever type with multiple electrodes, the electrostatic sensors of comb type and piezoelectric sensors are used for the single molecule detection of ligands. The electrical driving of sensors is separated in some cases from the sensing for increased sensitivity. The large arrays of sensors with individual or common sensing circuits are employed to further improve detection sensitivity. The fabrication of the sensors, their functionalization for detection of many chemical and biological species and electrical circuitry, packaging, microfluidic subsystem and the system architecture are also disclosed. The individual, specific sensing of single species or simultaneous detection of multiple species is realized. The freeze drying or critical point drying after exposure of sensors to ligands present in liquids and detection in reduced pressure or vacuum is employed for increased sensitivity, down to the single molecule.

2. 发明授权

US10052052B2 Optical sensing array architectures for spatial profiling 有权
公开(公告)号：US10052052B2
公开(公告)日：2018-08-21
申请号：US14306228
申请日：2014-06-17
申请人： Vlad Joseph Novotny
发明人： Vlad Joseph Novotny
IPC分类号： A61B5/00 , A61B5/1455 , A61B5/145 , G01J3/00 , G01N21/47 , G01N21/49 , G01N21/39 , G01N21/35
CPC分类号： A61B5/1455 , A61B5/00 , A61B5/0075 , A61B5/14532 , G01J3/00 , G01J3/0205 , G01J3/108 , G01J3/42 , G01J3/433 , G01J3/45 , G01J2003/1213 , G01N21/39 , G01N21/4738 , G01N21/49 , G01N2021/3595
摘要： Multiple optical architectures based on photosensitive arrays are disclosed. The optical engines collect five dimensional data from the samples with three dimensional spatial information and temporal and spectral information simultaneously, in parallel from all channels, without optical scanning. The photosensitive arrays and/or last component of illumination system are in contact or close proximity of the sample surface. The application of optical engines to sensitive detection of species of interest in the complex reflecting and scattering matrix with the high concentration of interfering species is described. The optical engines are applicable to noninvasive, mobile monitoring of various species of interest in vivo and in vitro.

3. 发明申请

US20150362427A1 Optical Sensing Array Architectures for Spatial Profiling 审中-公开
标题翻译：用于空间分析的光学感测阵列结构
公开(公告)号：US20150362427A1
公开(公告)日：2015-12-17
申请号：US14306228
申请日：2014-06-17
申请人： Vlad Joseph Novotny
发明人： Vlad Joseph Novotny
IPC分类号： G01N21/3577 , A61B5/145 , A61B5/1455 , G01N21/39
CPC分类号： A61B5/1455 , A61B5/00 , A61B5/0075 , A61B5/14532 , G01J3/00 , G01J3/0205 , G01J3/108 , G01J3/42 , G01J3/433 , G01J3/45 , G01J2003/1213 , G01N21/39 , G01N21/4738 , G01N21/49 , G01N2021/3595
摘要： Multiple optical architectures based on photosensitive arrays are disclosed. The optical engines collect five dimensional data from the samples with three dimensional spatial information and temporal and spectral information simultaneously, in parallel from all channels, without optical scanning. The photosensitive arrays and/or last component of illumination system are in contact or close proximity of the sample surface. The application of optical engines to sensitive detection of species of interest in the complex reflecting and scattering matrix with the high concentration of interfering species is described. The optical engines are applicable to noninvasive, mobile monitoring of various species of interest in vivo and in vitro.
摘要翻译：公开了基于光敏阵列的多种光学架构。光学引擎从具有三维空间信息和时间和频谱信息的样本中收集五维数据，与所有通道并行，而无需光学扫描。光敏阵列和/或照明系统的最后部件与样品表面接触或接近。描述了光引擎在具有高浓度干扰物质的复反射和散射基质中敏感检测感兴趣物种的应用。光学引擎适用于体内和体外各种感兴趣物种的无创移动监测。

4. 发明申请

US20160273968A1 Sealed Infrared Imagers and Sensors 审中-公开
标题翻译：密封红外成像器和传感器
公开(公告)号：US20160273968A1
公开(公告)日：2016-09-22
申请号：US14658242
申请日：2015-03-16
申请人： Vlad Joseph Novotny
发明人： Vlad Joseph Novotny
IPC分类号： G01J5/20 , H01L31/09 , B81C1/00 , H01L31/18
CPC分类号： B81C1/00285 , B81B2201/0207 , B81B2203/0109 , B81B2207/015 , B81C1/00333 , B81C2203/0136 , B81C2203/0145 , G01J5/024 , G01J5/045 , G01J5/24 , G01J2005/204 , H01L27/14643
摘要： The architecture, design and fabrication of array of suspended micro-elements with individual seals are described. Read out integrated circuit is integrated monolithically with the suspended elements for low parasitics and high signal to noise ratio detection of changes of their electrical resistance. Array of individually sealed, suspended micro-elements is combined with signal processing chip that contains nonvolatile memory with sensitivity calibration of all elements and interpolation between non-functional elements. When the micro-elements are infrared light absorbers, image analysis and recognition is embedded in the processing chip to form the infrared imaging solution for infrared cameras.
摘要翻译：描述了具有单独密封件的悬浮微型元件阵列的架构，设计和制造。读出集成电路与悬挂元件整体集成，用于低寄生效应和高信噪比检测其电阻变化。单独密封的悬浮微元件阵列与包含非易失性存储器的信号处理芯片组合，具有所有元件的灵敏度校准和非功能元件之间的插值。当微元件是红外光吸收器时，图像分析和识别被嵌入处理芯片中，以形成用于红外相机的红外成像解决方案。

5. 发明授权

US09410850B2 Infrared imager readout electronics 有权
标题翻译：红外成像仪读出电子
公开(公告)号：US09410850B2
公开(公告)日：2016-08-09
申请号：US14032205
申请日：2013-09-20
申请人： Vlad Joseph Novotny , Howard Woo
发明人： Vlad Joseph Novotny , Howard Woo
IPC分类号： G01J5/24 , H04N5/33 , H04N5/3745 , H04N5/378 , H04N5/353 , H04N5/355 , H04N5/357
CPC分类号： G01J5/24 , H04N5/33 , H04N5/3535 , H04N5/35554 , H04N5/3575 , H04N5/37455 , H04N5/378
摘要： Readout integrated circuits placed underneath the suspended sensing elements detect changes of electrical resistance of sensing elements and digitize the signals with digital to analog convertor for each element. Readout electronics provides low parasitics, high signal to noise ratio, high data rate, high dynamic range and instantaneous global readout.
摘要翻译：放置在悬挂感应元件下方的读出集成电路检测感测元件的电阻变化，并对每个元件的数模转换器数字化信号。读出电子提供低寄生效应，高信噪比，高数据速率，高动态范围和瞬时全局读出。

6. 发明申请

US20140239179A1 Sealed Infrared Imagers 审中-公开
标题翻译：密封红外成像仪
公开(公告)号：US20140239179A1
公开(公告)日：2014-08-28
申请号：US13775217
申请日：2013-02-24
申请人： Vlad Joseph Novotny , Howard Woo
发明人： Vlad Joseph Novotny , Howard Woo
IPC分类号： G01J5/20 , H01L31/09 , H01L31/18
CPC分类号： G01J5/20 , G01J5/0225 , G01J5/048 , G01J2005/204 , H01L31/0203 , H01L31/09 , H01L31/18
摘要： The architecture, design and fabrication of array of suspended micro-elements with individual seals are described. Read out integrated circuit is integrated monolithically with the suspended elements for low parasitics and high signal to noise ratio detection of changes of their electrical resistance. Array of individually sealed, suspended micro-elements is combined with signal processing chip that contains nonvolatile memory with sensitivity calibration of all elements and interpolation between non-functional elements. When the micro-elements are infrared light absorbers, image analysis and recognition is embedded in the processing chip to form the infrared imaging solution for infrared cameras.
摘要翻译：描述了具有单独密封件的悬浮微型元件阵列的架构，设计和制造。读出集成电路与悬挂元件整体集成，用于低寄生效应和高信噪比检测其电阻变化。单独密封的悬浮微元件阵列与包含非易失性存储器的信号处理芯片组合，具有所有元件的灵敏度校准和非功能元件之间的插值。当微元件是红外光吸收器时，图像分析和识别被嵌入处理芯片中，以形成用于红外相机的红外成像解决方案。

7. 发明授权

US06289564B1 Method of making a piezoelectric microactuator for precise head positioning 有权
标题翻译：制造用于精确头部定位的压电微致动器的方法
公开(公告)号：US06289564B1
公开(公告)日：2001-09-18
申请号：US09345265
申请日：1999-06-30
申请人： Vlad Joseph Novotny
发明人： Vlad Joseph Novotny
IPC分类号： H01L4100
CPC分类号： G11B5/5552 , G11B5/5556 , H01L41/081 , H01L41/094 , H01L41/314 , Y10T29/42 , Y10T29/49025 , Y10T29/49041 , Y10T29/49812
摘要： A slider assembly for selectively altering a position of a transducing head with respect to a track of a rotatable disc having a plurality of concentric tracks includes a slider body having a main portion and a head portion separated by a gap. The head portion carries the transducing head. The slider body is arranged to be supported by a support structure over a surface of the rotatable disc. A pair of structural elements are disposed on opposite side surfaces of the slider body between the main portion and the head portion across the gap. At least one of the structural elements is a microactuator responsive to electrical control signals to selectively bend to alter the position of the head portion with respect to the main portion of the slider body. The structural elements may be complementary microactuators. The microactuators may be formed by a process involving forming the microactuators on a slider substrate or on a row of sliders, forming the microactuators on a slider stack, or separately forming the microactuators and attaching the microactuators to a slider stack.
摘要翻译：用于选择性地改变换能头相对于具有多个同心轨道的可旋转盘的轨道的位置的滑块组件包括具有主要部分和由间隙分开的头部的滑块体。头部承载换能头。滑块主体被布置成由可旋转盘的表面上的支撑结构支撑。一对结构元件设置在跨越间隙的主体部分和头部之间的滑块体的相对侧表面上。结构元件中的至少一个是响应于电控制信号的微致动器，其选择性地弯曲以改变头部相对于滑块体的主要部分的位置。结构元件可以是互补微致动器。微致动器可以通过包括在滑动器基板或一排滑块上形成微致动器的方法形成，在滑块上形成微致动器，或者单独地形成微致动器并将微致动器附接到滑块。

8. 发明授权

US5734519A Contact magnetic recording disk file with improved head assembly 失效
标题翻译：接触磁记录磁盘文件，改进头组件
公开(公告)号：US5734519A
公开(公告)日：1998-03-31
申请号：US37064
申请日：1993-03-25
申请人： Robert Edward Fontana, Jr. , Cherngye Hwang , Vlad Joseph Novotny , Timothy Clark Reiley , Celia Elizabeth Yeack-Scranton , Clinton David Snyder
发明人： Robert Edward Fontana, Jr. , Cherngye Hwang , Vlad Joseph Novotny , Timothy Clark Reiley , Celia Elizabeth Yeack-Scranton , Clinton David Snyder
IPC分类号： G11B5/31 , G11B5/10 , G11B5/187 , G11B5/255 , G11B5/39 , G11B5/48
CPC分类号： G11B5/484 , G11B5/10 , G11B5/255
摘要： A contact recording disk file uses an integrated head-suspension assembly having a head carrier with a dual-layer wear pad for contacting the disk during read and write operations. The outer wear layer of the pad is relatively soft and wear prone compared to a harder and more wear-resistant inner layer. The outer wear layer wears away at a relatively rapid rate during initial wear-in of the head carrier. In this manner the head pole pieces, which extend into the wear pad, are rapidly put into contact with the disk, thereby compensating for initial misalignment of the wear pad with the surface of the disk. The inner wear layer then provides wear resistance over the life of the disk file. In the preferred embodiment, both the outer and inner wear layers are formed of essentially amorphous carbon doped with different amounts of hydrogen.
摘要翻译：接触式记录磁盘文件使用集成的头悬挂组件，其具有带有双层磨损垫的头部托架，用于在读取和写入操作期间接触盘。相对于较硬和更耐磨的内层，该垫的外部耐磨层相对较软并且容易发生倾向。在头托架的初始磨损期间，外磨损层以相对较快的速度磨损。以这种方式，延伸到耐磨垫中的头部极片迅速地与盘接触，从而补偿磨损垫与盘表面的初始不对准。然后，内部磨损层在磁盘文件的使用寿命内提供耐磨性。在优选实施例中，外耐磨层和内耐磨层均由掺杂有不同量氢的基本无定形碳形成。

9. 发明授权

US09140667B2 Chemical and biomedical NanoSensors 有权
标题翻译：化学和生物医学纳米传感器
公开(公告)号：US09140667B2
公开(公告)日：2015-09-22
申请号：US13209442
申请日：2011-08-15
申请人： Vlad Joseph Novotny
发明人： Vlad Joseph Novotny
IPC分类号： G01N29/036 , G01N29/02 , B82Y15/00
CPC分类号： G01N29/2437 , B82Y15/00 , G01N29/022 , G01N2291/014 , G01N2291/02416 , G01N2291/02466 , G01N2291/0255 , G01N2291/0256 , G01N2291/0257
摘要： The electrostatic sensors of bridge or cantilever type with multiple electrodes, the electrostatic sensors of comb type and piezoelectric sensors are used for the single molecule detection of ligands. The electrical driving of sensors is separated in some cases from the sensing for increased sensitivity. The large arrays of sensors with individual or common sensing circuits are employed to further improve detection sensitivity. The fabrication of the sensors, their functionalization for detection of many chemical and biological species and electrical circuitry, packaging, microfluidic subsystem and the system architecture are also disclosed. The individual, specific sensing of single species or simultaneous detection of multiple species is realized. The freeze drying or critical point drying after exposure of sensors to ligands present in liquids and detection in reduced pressure or vacuum is employed for increased sensitivity, down to the single molecule.
摘要翻译：具有多个电极的桥式或悬臂式静电传感器，梳型静电传感器和压电传感器用于配体的单分子检测。传感器的电驱动在某些情况下与传感器分离以提高灵敏度。使用具有单独或公共感测电路的大型传感器阵列来进一步提高检测灵敏度。还公开了传感器的制造，其用于检测许多化学和生物物种以及电路，封装，微流体子系统和系统架构的功能化。实现单个物种的个体特异性感测或多种物种的同时检测。将传感器暴露于存在于液体中的配体和在减压或真空中检测的冷冻干燥或临界点干燥被用于提高灵敏度，直到单个分子。

10. 发明授权

US09029773B2 Sealed infrared imagers 有权
标题翻译：密封红外成像仪
公开(公告)号：US09029773B2
公开(公告)日：2015-05-12
申请号：US13775217
申请日：2013-02-24
申请人： Vlad Joseph Novotny , Howard Woo
发明人： Vlad Joseph Novotny , Howard Woo
IPC分类号： G01J5/02 , G01J5/20 , H01L31/09 , H01L31/18
CPC分类号： G01J5/20 , G01J5/0225 , G01J5/048 , G01J2005/204 , H01L31/0203 , H01L31/09 , H01L31/18
摘要： The architecture, design and fabrication of array of suspended micro-elements with individual seals are described. Read out integrated circuit is integrated monolithically with the suspended elements for low parasitics and high signal to noise ratio detection of changes of their electrical resistance. Array of individually sealed, suspended micro-elements is combined with signal processing chip that contains nonvolatile memory with sensitivity calibration of all elements and interpolation between non-functional elements. When the micro-elements are infrared light absorbers, image analysis and recognition is embedded in the processing chip to form the infrared imaging solution for infrared cameras.
摘要翻译：描述了具有单独密封件的悬浮微型元件阵列的架构，设计和制造。读出集成电路与悬挂元件整体集成，用于低寄生效应和高信噪比检测其电阻变化。单独密封的悬浮微元件阵列与包含非易失性存储器的信号处理芯片组合，具有所有元件的灵敏度校准和非功能元件之间的插值。当微元件是红外光吸收器时，图像分析和识别被嵌入处理芯片中，以形成用于红外相机的红外成像解决方案。

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