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1. 发明申请

WO2007092640A3 ANTIBODIES THAT BIND PAR-2 审中-公开
公开(公告)号：WO2007092640A3
公开(公告)日：2007-08-16
申请号：PCT/US2007/003796
申请日：2007-02-09
申请人： AMGEN INC. , VIRCA, George, Duke , HU, Shaw-Fen, Sylvia
发明人： VIRCA, George, Duke , HU, Shaw-Fen, Sylvia
IPC分类号： C07K16/28 , A61K39/395 , A61P29/00
摘要： The present invention provides compositions and methods relating to or derived from anti-PAR-2 antibodies. In particular embodiments, the invention provides antibodies that bind human PAR-2, PAR-2-binding fragments and derivatives of such antibodies, and PAR-2-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having PAR-2-related disorders or conditions.

2. 发明申请

WO2007092640A2 ANTIBODIES THAT BIND PAR-2 审中-公开
标题翻译： BIND PAR-2的抗体
公开(公告)号：WO2007092640A2
公开(公告)日：2007-08-16
申请号：PCT/US2007003796
申请日：2007-02-09
申请人： AMGEN INC , VIRCA GEORGE DUKE , HU SHAW-FEN SYLVIA
发明人： VIRCA GEORGE DUKE , HU SHAW-FEN SYLVIA
CPC分类号： C07K16/28 , A61K2039/505 , C07K2317/34 , C07K2317/76 , C07K2317/92
摘要： The present invention provides compositions and methods relating to or derived from anti-PAR-2 antibodies. In particular embodiments, the invention provides antibodies that bind human PAR-2, PAR-2-binding fragments and derivatives of such antibodies, and PAR-2-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having PAR-2-related disorders or conditions.
摘要翻译：本发明提供了与抗PAR-2抗体有关或衍生自抗PAR-2抗体的组合物和方法。在具体实施方案中，本发明提供了结合人PAR-2，PAR-2-结合片段和此类抗体衍生物的抗体，以及包含此类片段的PAR-2结合多肽。其它实施方案提供编码此类抗体，抗体片段和衍生物和多肽的核酸，包含此类多核苷酸的细胞，制备此类抗体的方法，抗体片段和衍生物和多肽，以及使用此类抗体，抗体片段和衍生物和多肽的方法，包括方法治疗或诊断患有PAR-2相关疾病或病症的受试者。

3. 发明申请

WO2009005726A1 ANTIGEN BINDING PROTEINS THAT BIND PAR-2 审中-公开
标题翻译：抗体结合蛋白质，包括PAR-2
公开(公告)号：WO2009005726A1
公开(公告)日：2009-01-08
申请号：PCT/US2008/008037
申请日：2008-06-26
申请人： AMGEN INC. , VIRCA, George Duke , HU, Shaw-fen Sylvia
发明人： VIRCA, George Duke , HU, Shaw-fen Sylvia
IPC分类号： C07K16/28 , A61K39/395 , A61P19/02 , A61P29/00
CPC分类号： C07K16/28 , A61K2039/505 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2319/30
摘要： The present invention provides compositions and methods relating to or derived from anti-PAR-2 antibodies. In particular embodiments, the invention provides human antibodies that bind PAR-2, PAR-2-binding fragments and derivatives of such antibodies, and PAR-2-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having PAR-2-related disorders or conditions.
摘要翻译：本发明提供了与抗PAR-2抗体有关或衍生自抗PAR-2抗体的组合物和方法。在具体实施方案中，本发明提供了结合PAR-2，PAR-2结合片段和此类抗体的衍生物的人抗体，以及包含此类片段的PAR-2结合多肽。其他实施方案提供编码此类抗体，抗体片段和衍生物和多肽的核酸，包含此类多核苷酸的细胞，制备此类抗体的方法，抗体片段和衍生物和多肽，以及使用此类抗体，抗体片段和衍生物和多肽的方法，包括方法治疗或诊断患有PAR-2相关疾病或病症的受试者。

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