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1. 发明专利

CA2320543A1 DISPOSITIF DE RECUPERATION DE PURGE POUR SYSTEME DE REFRIGIRATION A AMONIAC 未知
公开(公告)号：CA2320543A1
公开(公告)日：2001-10-09
申请号：CA2320543
申请日：2000-09-21
申请人： VILLENEUVE LUC , CLEMENT LUC
发明人： VILLENEUVE LUC , CLEMENT LUC
IPC分类号： F25B9/00 , F25B41/00 , F25B45/00
摘要： Le dispositif de récupération de la purge a pour but de protéger en premier lieu la santé des travailleurs qui sont exposés à un très haut risque, à une exposition aux vapeurs nocives d'ammoniac sous forme d'huile et de vapeur. Le procédé étant à haut risque a démontré à maintes reprises son inefficacité, résultant des inhalations de vapeur par l es travailleurs. Le dispositif a donc un impact double, la santé des travailleurs et une possibilité de recyclage à 100% de ses huiles usées.

2. 发明专利

CA2260217A1 IRRADIATING APPARATUS USING A SCANNING LIGHT SOURCE FOR PHOTODYNAMIC TREATMENT 未知
公开(公告)号：CA2260217A1
公开(公告)日：1998-01-29
申请号：CA2260217
申请日：1997-06-18
申请人： MILLER GERARD , VILLENEUVE LUC , BERNIER ROBERT , LAURENDEAU CLAUDE , THERATECHNOLOGIES INC
发明人： MILLER GERARD , VILLENEUVE LUC , PAL PRABIR KUMAR , BERNIER ROBERT , LAURENDEAU CLAUDE
IPC分类号： A61N5/10 , A61B17/00 , A61N5/01 , A61N5/06
摘要： An apparatus for irradiating a biological substance with a substantially uniform quantity of radiation energy comprises a radiation-generating device for producing radiation energy, a support structure for receiving the biological substance, and a motorized mechanism for reciprocating the radiation-generating device along a given path whereby the biological substance receives radiation energy from the radiation-generating device at each passage of the radiation-generating device. A series of sensors lie into a given plane and are subjected to radiation energy from the radiationgenerating device upon each passage of that radiation-generating device for sensing and measuring the quantity of radiation energy by surface unit passing through the given plane and reaching the biological substance. Finally the radiation-generating device and the motorized mechanism are de-energized when the measured quantity of radiation energy by surface unit has reached a predetermined value.

3. 发明申请

WO2005053743A1 IMMUNOLOGIC COMPOUNDS FOR PREVENTION, PROTECTION, PROPHYLAXIS OR TREATMENT OF IMMUNOLOGICAL DISORDERS, INFECTIONS AND CANCER 审中-公开
标题翻译：用于预防，保护，预防或治疗免疫缺陷病毒，感染和癌症的免疫化学物质
公开(公告)号：WO2005053743A1
公开(公告)日：2005-06-16
申请号：PCT/CA2004/002070
申请日：2004-12-02
申请人： UNIVERSITÉ DE MONTRÉAL , HÔPITAL MAISONNEUVE-ROSEMONT , ROY, Denis Claude , VAILLANCOURT, Marc , VILLENEUVE, Luc
发明人： ROY, Denis Claude , VAILLANCOURT, Marc , VILLENEUVE, Luc
IPC分类号： A61K41/00
CPC分类号： A61K31/353 , A61K31/365 , A61K35/28 , A61K38/193 , A61K38/2013 , A61K38/21 , A61K39/0008 , A61K39/0011 , A61K41/0019 , A61K41/0057 , A61K2039/5154 , Y02A50/414 , A61K2300/00
摘要： The present invention relates to the use of PDT-treated cells (whole or fragments thereof) and/or supernatant thereof in the preparation of vaccines for immunoprotection or immunomodulation. More particularly, the use of PDT-treated cells (whole or fragments thereof) and/or supernatant thereof in the preparation of an immunologic compound for prevention, protection, prophylaxis or treatment of an immunological disorder, infection and/or a cancer in an individual, which comprises treatment of the individual cells or components thereof with a photoactivatable molecule selected from the group consisting of compounds I to XVIII, wherein the photoactivatable molecule is activated by a light of appropriate wavelength, thereby activating the photoactivatable molecule and causing prevention, protection, prophylaxis or treatment of the immunological disorder, infection and/or a cancer.
摘要翻译：本发明涉及PDT处理的细胞（其全部或其片段）和/或上清液在免疫保护或免疫调节疫苗的制备中的用途。更具体地说，PDT处理的细胞（其全部或其片段）和/或其上清液在制备免疫化合物中用于预防，保护，预防或治疗个体中的免疫疾病，感染和/或癌症的用途其包括用选自化合物I至XVIII的可光活化分子处理单个细胞或其组分，其中可光活化分子由适当波长的光激活，由此活化可光活化分子并引起预防，保护，预防或治疗免疫学疾病，感染和/或癌症。

4. 发明申请

WO2002079183A1 HALOGENATED RHODAMINE DERIVATIVES AND APPLICATIONS THEREOF 审中-公开
标题翻译：恶唑罗丹明衍生物及其应用
公开(公告)号：WO2002079183A1
公开(公告)日：2002-10-10
申请号：PCT/CA2002/000438
申请日：2002-03-27
申请人： THERATECHNOLOGIES INC. , HABI, Abdelkrim , GRAVEL, Denis , VILLENEUVE, Luc , FORTÉ, Jean-Pierre , SU, Hongsheng , VAILLANCOURT, Marc
发明人： HABI, Abdelkrim , GRAVEL, Denis , VILLENEUVE, Luc , FORTÉ, Jean-Pierre , SU, Hongsheng , VAILLANCOURT, Marc
IPC分类号： C07D311/82
CPC分类号： C07D311/82
摘要： Novel compounds of the formula (I) wherein: one of R1, R2, R3, R4, and (R10)n represents an halogen atom and each of the remaining R1, R2, R3, R4, and each of the remaining R10 group is independently selected in the group constituted by hydrogen, halogen atoms, an amino, acylamino, dialkylamino, cycloalkylamino, azacycloalkyl, alkylcycloalkylamino, aroylamino, diarylamino, arylalkylamino, aralkylamino, alkylaralkylamino, arylaralkylamino, hydroxy, alkoxy, aryloxy, aralkyloxy, mercapto, alkylthio, arylthio, aralkylthio, carboxyl, alkoxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, cyano, hydroxysulfonyl, amidosulfonyl, dialkylamidosulfonyl, arylalkylamidosulfonyl, formyl, acyl, aroyl, alkyl, alkylene, alkenyl, aryl, aralkyl, vinyl, alkynyl group and by the corresponding substituted groups; - m = 0 - 1; n = 1-4, A is nil, O, or NH; R9 represents an alkylene group; -Z is H, amino, dialkylamino, or trialkylamino salt; X- is an anion; R5, R6, R7 and R8 are independently H or C1-C6 alkyl or R1 in combination with R5 or R6, or R2 in combination with R5 or R6, or R3 in combination with R7 or R8, or R4in combination with R7 or R8 represents an alkylene, alone or in association with a pharmaceutically acceptable carrier. These compounds, which are usefull as intermediate and as bactericides, as antiviral agent and in the treatment of immunologic disoders.
摘要翻译：式（I）的新型化合物其中：R 1，R 2，R 3，R 4和（R 10）中的一个表示卤素原子，剩余的R 1，R 2，R 3，R 4及其余R 10基中的每一个为在由氢，卤素原子，氨基，酰氨基，二烷基氨基，环烷基氨基，氮杂环烷基，烷基环烷基氨基，芳酰氨基，二芳基氨基，芳基烷基氨基，芳烷基氨基，烷基烷基氨基，芳基芳基氨基，羟基，烷氧基，芳氧基，芳烷氧基，巯基，，芳烷硫基，羧基，烷氧基羰基，芳氧基羰基，芳烷氧基羰基，氨基甲酰基，烷基氨基甲酰基，二烷基氨基甲酰基，氰基，羟基磺酰基，酰氨基磺酰基，二烷基氨基磺酰基，芳基烷基氨基磺酰基，甲酰基，酰基，芳酰基，烷基，亚烷基，烯基，芳基，芳烷基，乙烯基，炔基相应的取代基; - m = 0-1; n = 1-4，A为无，O或NH; R9表示亚烷基; -Z是H，氨基，二烷基氨基或三烷基氨基盐; X-是阴离子; R5，R6，R7和R8独立地是H或C1-C6烷基或R1与R5或R6组合，或R2与R5或R6组合，或R3与R7或R8组合，或R4in与R7或R8的组合表示单独或与药学上可接受的载体结合的亚烷基。这些化合物可用作中间体和杀菌剂，作为抗病毒剂和治疗免疫学解码器。

5. 发明申请

WO02079183A8 HALOGENATED RHODAMINE DERIVATIVES AND APPLICATIONS THEREOF 审中-公开
标题翻译：恶唑罗丹明衍生物及其应用
公开(公告)号：WO02079183A8
公开(公告)日：2003-02-20
申请号：PCT/CA0200438
申请日：2002-03-27
申请人： THERATECHNOLOGIES INC , HABI ABDELKRIM , GRAVEL DENIS , VILLENEUVE LUC , SU HONGSHENG , VAILLANCOURT MARC
发明人： HABI ABDELKRIM , GRAVEL DENIS , VILLENEUVE LUC , SU HONGSHENG , VAILLANCOURT MARC
IPC分类号： A61K31/352 , A61N5/06 , A61P31/00 , A61P31/04 , A61P31/12 , A61P35/00 , A61P35/02 , A61P37/00 , C07D311/82 , C07D493/10
CPC分类号： C07D311/82
摘要： Novel compounds of the formula (I) wherein: one of R1, R2, R3, R4, and (R10)n represents an halogen atom and each of the remaining R1, R2, R3, R4, and each of the remaining R10 group is independently selected in the group constituted by hydrogen, halogen atoms, an amino, acylamino, dialkylamino, cycloalkylamino, azacycloalkyl, alkylcycloalkylamino, aroylamino, diarylamino, arylalkylamino, aralkylamino, alkylaralkylamino, arylaralkylamino, hydroxy, alkoxy, aryloxy, aralkyloxy, mercapto, alkylthio, arylthio, aralkylthio, carboxyl, alkoxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, cyano, hydroxysulfonyl, amidosulfonyl, dialkylamidosulfonyl, arylalkylamidosulfonyl, formyl, acyl, aroyl, alkyl, alkylene, alkenyl, aryl, aralkyl, vinyl, alkynyl group and by the corresponding substituted groups; - m = 0 - 1; n = 1-4, A is nil, O, or NH; R9 represents an alkylene group; -Z is H, amino, dialkylamino, or trialkylamino salt; X- is an anion; R5, R6, R7 and R8 are independently H or C1-C6 alkyl or R1 in combination with R5 or R6, or R2 in combination with R5 or R6, or R3 in combination with R7 or R8, or R4in combination with R7 or R8 represents an alkylene, alone or in association with a pharmaceutically acceptable carrier. These compounds, which are usefull as intermediate and as bactericides, as antiviral agent and in the treatment of immunologic disoders.
摘要翻译：式（I）的新型化合物其中：R 1，R 2，R 3，R 4和（R 10）中的一个表示卤素原子，剩余的R 1，R 2，R 3，R 4及其余R 10基中的每一个为在由氢，卤素原子，氨基，酰氨基，二烷基氨基，环烷基氨基，氮杂环烷基，烷基环烷基氨基，芳酰氨基，二芳基氨基，芳基烷基氨基，芳烷基氨基，烷基烷基氨基，芳基芳基氨基，羟基，烷氧基，芳氧基，芳烷氧基，巯基，，芳烷硫基，羧基，烷氧基羰基，芳氧基羰基，芳烷氧基羰基，氨基甲酰基，烷基氨基甲酰基，二烷基氨基甲酰基，氰基，羟基磺酰基，酰氨基磺酰基，二烷基氨基磺酰基，芳基烷基氨基磺酰基，甲酰基，酰基，芳酰基，烷基，亚烷基，烯基，芳基，芳烷基，乙烯基，炔基相应的取代基; - m = 0-1; n = 1-4，A为无，O或NH; R9表示亚烷基; -Z是H，氨基，二烷基氨基或三烷基氨基盐; X-是阴离子; R5，R6，R7和R8独立地是H或C1-C6烷基或R1与R5或R6组合，或R2与R5或R6组合，或R3与R7或R8组合，或R4in与R7或R8的组合表示单独或与药学上可接受的载体结合的亚烷基。这些化合物可用作中间体和杀菌剂，作为抗病毒剂和治疗免疫学解码器。

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