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    • 3. 发明申请
    • VENTRICULAR RATE STABILIZATION WITH CARDIAC RESYNCHRONIZATION
    • 心脏再生能力的稳定性稳定性
    • WO2004096341A3
    • 2005-03-24
    • PCT/US2004012263
    • 2004-04-20
    • MEDTRONIC INCVAN OORT GEESKEVAN HOVE JOS W
    • VAN OORT GEESKEVAN HOVE JOS W
    • A61N1/368
    • A61N1/368A61N1/3684
    • An implantable medical device (IMD) selectively switches to a more hemodynamically beneficial pacing mode upon detection of ventricular dysynchrony and/or reduced hemodynamic function during delivery of pacing pulses according to a ventricular rate stabilization algorithm. For example, in some embodiments of the invention, an IMD switches from right ventricular pacing according to a ventricular rate stabilization algorithm, to biventricular pacing according to the algorithm. The biventricular pacing can be provided according to a cardiac resynchronization therapy mode, and can involve use of an intraventricular delay between delivery of pacing pulses to the respective ventricles to improve hemodynamic functioning of a heart. The IMD monitors an electrogram signal to detect ventricular dysynchrony and/or decreased hemodynamic performance of the ventricles. The IMD can detect ventricular dysynchrony based on elongated QRS complex widths. The IMD can detect decreased hemodynamic performance based on shortened Q-T intervals and/or decreased ventricular evoked response amplitudes.
    • 根据心室速率稳定算法,可以在检测到心室异常和/或在递送起搏脉冲期间降低的血液动力学功能时,可植入医疗装置(IMD)选择性地切换到更有效的起搏方式。 例如,在本发明的一些实施例中,IMD根据心室速率稳定算法从右心室起搏切换到根据该算法的双心室起搏。 可以根据心脏再同步治疗模式提供双心室起搏,并且可以涉及在将起搏脉冲递送到各个心室之间使用室内延迟以改善心脏的血液动力学功能。 IMD监测电描记图信号以检测心室异常和/或降低心室的血液动力学性能。 IMD可以根据延长的QRS复杂宽度来检测心室异常。 IMD可以基于缩短的Q-T间期和/或降低的心室诱发反应幅度来检测血液动力学性能降低。
    • 4. 发明申请
    • VENTRICULAR RATE STABILIZATION WITH CARDIAC RESYNCHRONIZATION
    • 心脏再生能力的稳定性稳定性
    • WO2004096341A2
    • 2004-11-11
    • PCT/US2004/012263
    • 2004-04-20
    • MEDTRONIC, INC.VAN OORT, GeeskeVAN HOVE, Jos, W.
    • VAN OORT, GeeskeVAN HOVE, Jos, W.
    • A61N
    • A61N1/368A61N1/3684
    • An implantable medical device (IMD) selectively switches to a more hemodynamically beneficial pacing mode upon detection of ventricular dysynchrony and/or reduced hemodynamic function during delivery of pacing pulses according to a ventricular rate stabilization algorithm. For example, in some embodiments of the invention, an IMD switches from right ventricular pacing according to a ventricular rate stabilization algorithm, to biventricular pacing according to the algorithm. The biventricular pacing can be provided according to a cardiac resynchronization therapy mode, and can involve use of an intraventricular delay between delivery of pacing pulses to the respective ventricles to improve hemodynamic functioning of a heart. The IMD monitors an electrogram signal to detect ventricular dysynchrony and/or decreased hemodynamic performance of the ventricles. The IMD can detect ventricular dysynchrony based on elongated QRS complex widths. The IMD can detect decreased hemodynamic performance based on shortened Q-T intervals and/or decreased ventricular evoked response amplitudes.
    • 根据心室速率稳定算法,可以在检测到心室异常和/或在递送起搏脉冲期间降低的血液动力学功能时,可植入医疗装置(IMD)选择性地切换到更有效的起搏方式。 例如,在本发明的一些实施例中,IMD根据心室速率稳定算法从右心室起搏切换到根据该算法的双心室起搏。 可以根据心脏再同步治疗模式提供双心室起搏,并且可以涉及在将起搏脉冲递送到各个心室之间使用室内延迟以改善心脏的血液动力学功能。 IMD监测电描记图信号以检测心室异常和/或降低心室的血液动力学性能。 IMD可以根据延长的QRS复杂宽度来检测心室异常。 IMD可以基于缩短的Q-T间期和/或降低的心室诱发反应幅度来检测血液动力学性能降低。