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1. 发明申请

US20110249229A1 LIQUID CRYSTAL DISPLAY DEVICE 有权
标题翻译：液晶显示装置
公开(公告)号：US20110249229A1
公开(公告)日：2011-10-13
申请号：US13083114
申请日：2011-04-08
申请人： Daisuke KUBOTA , Akio YAMASHITA , Tetsuji ISHITANI , Tomohiro TAMURA
发明人： Daisuke KUBOTA , Akio YAMASHITA , Tetsuji ISHITANI , Tomohiro TAMURA
IPC分类号： G02F1/1343
CPC分类号： G02F1/134363 , G02F1/133707 , G02F1/134309 , G02F1/1395 , G02F2001/133622 , G02F2001/134318 , G02F2001/13793
摘要： A liquid crystal display device using a liquid crystal material exhibiting a blue phase is provided to achieve higher contrast. Further, the power consumption of the liquid crystal display device using a liquid crystal exhibiting a blue phase is reduced. In a liquid crystal display device including: a first substrate provided with a pixel electrode layer (also referred to as a first electrode layer); and a second substrate provided with a common electrode layer (also referred to as a second electrode layer), between which a liquid crystal layer exhibiting a blue phase is interposed, the pixel electrode layer and the common electrode layer project into the liquid crystal layer and are arranged so that the adjacent pixel electrode layer and common electrode layer engage with each other at a distance with the liquid crystal layer interposed therebetween.
摘要翻译：提供了使用表现蓝相的液晶材料的液晶显示装置，以实现更高的对比度。此外，使用显示蓝相的液晶的液晶显示装置的功耗降低。一种液晶显示装置，包括：第一基板，设置有像素电极层（也称为第一电极层）; 以及设置有公共电极层（也称为第二电极层）的第二基板，其间插有呈现蓝相的液晶层，像素电极层和公共电极层突出到液晶层中，被布置成使得相邻的像素电极层和公共电极层彼此间隔地间隔着液晶层。

2. 发明申请

US20110201640A1 TRICYCLIC COMPOUND 有权
标题翻译：三聚体化合物
公开(公告)号：US20110201640A1
公开(公告)日：2011-08-18
申请号：US13057599
申请日：2009-08-06
申请人： Arata Yanagisawa , Keiji Uehara , Masahiro Matsubara , Kimihisa Ueno , Michihiko Suzuki , Takeshi Kuboyama , Keisuke Yamamoto , Tomohiro Tamura
发明人： Arata Yanagisawa , Keiji Uehara , Masahiro Matsubara , Kimihisa Ueno , Michihiko Suzuki , Takeshi Kuboyama , Keisuke Yamamoto , Tomohiro Tamura
IPC分类号： A61K31/4184 , C07D235/16 , C07D403/06 , C07D413/10 , A61K31/4245 , C07D471/04 , A61K31/437 , C07D413/14 , A61K31/41 , C07D405/14 , A61K31/422 , C07D491/044 , A61K31/4353 , A61P3/10 , A61P9/12 , A61P3/04 , A61P35/00
CPC分类号： C07D471/04 , A61K31/335 , A61K31/4184 , A61K31/422 , A61K31/4353 , A61K31/4409 , C07C255/34 , C07C255/44 , C07D235/08 , C07D235/16 , C07D257/04 , C07D403/10 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/10 , C07D413/14
摘要： Provided is a tricyclic compound having a PPAR γ agonist activity, which is represented by the general formula (I) wherein Z represents a single bond or the like, Y represents a hydrogen atom, lower alkyl optionally having substituent(s) or the like, X represents a hydrogen atom or the like, A represents aryl or the like, B and C are the same or different and each represents an aromatic carbocycle or the like, R4-R9 are the same or different and each represents hydrogen or the like, V represents a single bond or the like, R10 and R11 are the same or different and each represents hydrogen or the like, or a pharmaceutically acceptable salt thereof or the like:
摘要翻译：本发明提供具有PPARγ激动剂活性的三环化合物，其通式（I）表示，其中Z表示单键等，Y表示氢原子，任选具有取代基的低级烷基等， X表示氢原子等，A表示芳基等，B和C相同或不同，各自表示芳香族碳环等，R4-R9相同或不同，表示氢等， V表示单键等，R 10和R 11相同或不同，各自表示氢等，或其药学上可接受的盐等：

3. 发明申请

US20100326592A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE 有权
标题翻译：制造液晶显示装置的方法
公开(公告)号：US20100326592A1
公开(公告)日：2010-12-30
申请号：US12785797
申请日：2010-05-24
申请人： Tetsuji ISHITANI , Daisuke KUBOTA , Tomohiro TAMURA
发明人： Tetsuji ISHITANI , Daisuke KUBOTA , Tomohiro TAMURA
IPC分类号： B32B37/14 , B32B38/00 , B32B38/10
CPC分类号： G02F1/1341 , G02F1/1339 , G02F2001/13415 , G02F2001/13793 , Y10T156/1052
摘要： It is an object to provide a method for manufacturing a liquid crystal display device including a liquid crystal layer which exhibits a stable blue phase. The following steps are performed: a first step of forming a thermosetting first sealant so as to form a frame over a first substrate; a second step of forming a photocurable and thermosetting second sealant on an outer side than the first sealant over the first substrate; a third step of dropping a liquid crystal material which exhibits a blue phase at a given temperature on an inner side than the first sealant; a fourth step of attaching a second substrate to the first substrate in a reduced-pressure atmosphere; a fifth step of performing polymer stabilization treatment on the liquid crystal material; and a sixth step of curing the first sealant through heat treatment.
摘要翻译：本发明的目的是提供一种液晶显示装置的制造方法，该液晶显示装置包括具有稳定的蓝相的液晶层。执行以下步骤：形成热固性第一密封剂以在第一基板上形成框架的第一步骤; 在第一基板上在第一密封剂的外侧上形成光固化和热固化的第二密封剂的第二步骤; 在比第一密封剂内侧在给定温度下放置显示蓝相的液晶材料的第三步骤; 在减压气氛中将第二基板附着到第一基板的第四步骤; 在液晶材料上进行聚合物稳定化处理的第五步骤; 以及通过热处理固化第一密封剂的第六步骤。

4. 发明申请

US20100297712A1 HYDROXYLASE GENE AND USE THEREOF 有权
标题翻译：羟基酶基因及其用途
公开(公告)号：US20100297712A1
公开(公告)日：2010-11-25
申请号：US12302876
申请日：2007-05-15
申请人： Yoshikazu Fujii , Tomohiro TAMURA
发明人： Yoshikazu Fujii , Tomohiro TAMURA
IPC分类号： C12P7/02 , C07H21/04 , C12N9/02 , C12N1/21
CPC分类号： C12P7/22 , C12N9/0071 , C12P7/02
摘要： A vitamin D3 hydroxylase is purified from Pseudonocardia autotrophica cell, and a primer is designed based on amino acid sequence obtained from hydroxylase. Subsequently, PCR is conducted using genomic DNA of Pseudonocardia autotrophica as a template to clone a gene for the vitamin D3 hydroxylase. By conducting a conversion reaction using a microorganism in which the vitamin D3 hydroxylase gene is expressed using a proper expression system, a hydroxide of vitamin D or the like (e.g., hydroxy vitamin D3) can be produced with high efficiency.
摘要翻译：维生素D3羟化酶从假诺卡氏菌属自养细胞中纯化，根据羟化酶获得的氨基酸序列设计引物。随后，使用假心内膜自养基因组DNA作为模板进行PCR，以克隆维生素D3羟化酶的基因。通过使用适当的表达系统来表达维生素D3羟化酶基因的微生物进行转化反应，可以高效率地生产维生素D等的氢氧化物（例如羟基维生素D3）。

5. 发明申请

US20060166312A1 Novel microorgnaism sensitive to lysozyme 有权
标题翻译：新型微生物对溶菌酶敏感
公开(公告)号：US20060166312A1
公开(公告)日：2006-07-27
申请号：US10524630
申请日：2003-08-14
申请人： Yasuo Mitani , Nobutaka Nakashima , Tomohiro Tamura
发明人： Yasuo Mitani , Nobutaka Nakashima , Tomohiro Tamura
IPC分类号： C12P21/06 , C07K14/195 , C12N1/21
CPC分类号： C12N1/20
摘要： A microorganism of the genus Rhodococcus is provided which has a higher sensitivity to lysozyme at a low concentration than a wild-type strain, which can easily cause cell lysis, and from which a recombinant protein expressed therein is easily recovered. More specifically, a mutant microorganism of the genus Rhodococcus having a higher sensitivity to lysozyme than a wild-type microorganism of the genus Rhodococcus.
摘要翻译：提供了一种具有比野生型菌株低的溶菌酶对溶菌酶的敏感性较高的微球菌，其可以容易地引起细胞裂解，并且其中表达的重组蛋白质容易回收。更具体地说，与红球菌属的野生型微生物相比，对溶菌酶敏感性高的红球菌属的突变微生物。

6. 发明授权

US09239497B2 Method for manufacturing liquid crystal display device 有权
标题翻译：制造液晶显示装置的方法
公开(公告)号：US09239497B2
公开(公告)日：2016-01-19
申请号：US12785797
申请日：2010-05-24
申请人： Tetsuji Ishitani , Daisuke Kubota , Tomohiro Tamura
发明人： Tetsuji Ishitani , Daisuke Kubota , Tomohiro Tamura
IPC分类号： B29C65/02 , B32B37/06 , B32B38/04 , G02F1/1341 , G02F1/1339 , G02F1/137
CPC分类号： G02F1/1341 , G02F1/1339 , G02F2001/13415 , G02F2001/13793 , Y10T156/1052
摘要： It is an object to provide a method for manufacturing a liquid crystal display device including a liquid crystal layer which exhibits a stable blue phase. The following steps are performed: a first step of forming a thermosetting first sealant so as to form a frame over a first substrate; a second step of forming a photocurable and thermosetting second sealant on an outer side than the first sealant over the first substrate; a third step of dropping a liquid crystal material which exhibits a blue phase at a given temperature on an inner side than the first sealant; a fourth step of attaching a second substrate to the first substrate in a reduced-pressure atmosphere; a fifth step of performing polymer stabilization treatment on the liquid crystal material; and a sixth step of curing the first sealant through heat treatment.
摘要翻译：本发明的目的是提供一种液晶显示装置的制造方法，该液晶显示装置包括具有稳定的蓝相的液晶层。执行以下步骤：形成热固性第一密封剂以在第一基板上形成框架的第一步骤; 在第一基板上在第一密封剂的外侧上形成光固化和热固化的第二密封剂的第二步骤; 在比第一密封剂内侧在给定温度下放置显示蓝相的液晶材料的第三步骤; 在减压气氛中将第二基板附着到第一基板的第四步骤; 在液晶材料上进行聚合物稳定化处理的第五步骤; 以及通过热处理固化第一密封剂的第六步骤。

7. 发明授权

US09006412B2 Expression vector for pseudonocardia autotrophica 有权
标题翻译：假诺卡氏菌属的表达载体
公开(公告)号：US09006412B2
公开(公告)日：2015-04-14
申请号：US13122675
申请日：2009-10-05
申请人： Yoshikazu Fujii , Tadashi Fujii , Akira Arisawa , Tomohiro Tamura
发明人： Yoshikazu Fujii , Tadashi Fujii , Akira Arisawa , Tomohiro Tamura
IPC分类号： C07H21/04 , C12N15/00 , C12N15/64 , C12P21/06 , C12P21/02 , C12N9/02 , C12N15/74 , C12P7/02 , C12P7/62 , C12P17/06
CPC分类号： C12P21/02 , C12N9/0071 , C12N9/0073 , C12N15/74 , C12P7/02 , C12P7/62 , C12P17/06 , C12Y114/13013
摘要： An expression vector capable of expressing a foreign gene in Pseudonocardia autotrophica; a transformant of Pseudonocardia autotrophica produced by using the expression vector; a method for producing a protein by using the transformant; a method for producing an active form of vitamin D3 from vitamin D3, which comprises highly expressing a gene encoding an enzyme involved in the synthesis of the active form of vitamin D3 in a transformant by using the expression vector or the transformant; a method for producing 25-hydroxyvitamin D2 from vitamin D2; and a method for producing pravastatin from compactin, which comprises highly expressing a compactin hydroxylase gene in a transformant by using the expression vector or the transformant.
摘要翻译：能够在自养假诺卡氏菌中表达外源基因的表达载体; 通过使用表达载体产生的假心内膜自养基因的转化体; 通过使用该转化体生产蛋白质的方法; 从维生素D3生产活性形式的维生素D3的方法，其包括通过使用表达载体或转化体高度表达编码参与转化体中活性形式的维生素D3的活性形式的酶的基因; 从维生素D2生产25-羟基维生素D 2的方法; 以及通过使用表达载体或转化体高效表达转化体中的致密蛋白羟化酶基因的来自美伐他汀的普伐他汀的制造方法。

8. 发明授权

US08148119B2 Hydroxylase gene and use thereof 有权
标题翻译：羟化酶基因及其用途
公开(公告)号：US08148119B2
公开(公告)日：2012-04-03
申请号：US12302876
申请日：2007-05-18
申请人： Yoshikazu Fujii , Tomohiro Tamura
发明人： Yoshikazu Fujii , Tomohiro Tamura
IPC分类号： C12P15/00 , C12N1/20 , C07H21/04
CPC分类号： C12P7/22 , C12N9/0071 , C12P7/02
摘要： A vitamin D3 hydroxylase is purified from Pseudonocardia autotrophica cell, and a primer is designed based on amino acid sequence obtained from hydroxylase. Subsequently, PCR is conducted using genomic DNA of Pseudonocardia autotrophica as a template to clone a gene for the vitamin D3 hydroxylase. By conducting a conversion reaction using a microorganism in which the vitamin D3 hydroxylase gene is expressed using a proper expression system, a hydroxide of vitamin D or the like (e.g., hydroxy vitamin D3) can be produced with high efficiency.
摘要翻译：维生素D3羟化酶从假诺卡氏菌属自养细胞中纯化，根据羟化酶获得的氨基酸序列设计引物。随后，使用假心内膜自养基因组DNA作为模板进行PCR，以克隆维生素D3羟化酶的基因。通过使用适当的表达系统来表达维生素D3羟化酶基因的微生物进行转化反应，可以高效率地生产维生素D等的氢氧化物（例如羟基维生素D3）。

9. 发明申请

US20110128491A1 LIQUID CRYSTAL DISPLAY DEVICE 有权
标题翻译：液晶显示装置
公开(公告)号：US20110128491A1
公开(公告)日：2011-06-02
申请号：US12952751
申请日：2010-11-23
申请人： Daisuke KUBOTA , Tetsuji ISHITANI , Akio YAMASHITA , Tomohiro TAMURA
发明人： Daisuke KUBOTA , Tetsuji ISHITANI , Akio YAMASHITA , Tomohiro TAMURA
IPC分类号： G02F1/1343
CPC分类号： G02F1/133707 , G02F1/134336 , G02F2001/13775 , G02F2001/13793
摘要： In the liquid crystal display device where a liquid crystal layer exhibiting a blue phase is interposed between a first substrate and a second substrate, a pixel electrode layer (first electrode layer) and a common electrode layer (second electrode layer) provided between the first substrate and the liquid crystal layer are positioned not to overlap with each other. The pixel electrode layer is formed to cover top and side surfaces of a rib-shaped first structure body which projects into the liquid crystal layer from a surface of the first substrate on the liquid crystal layer side. The common electrode layer is formed to cover top and side surfaces of a rib-shaped second structure body which projects into the liquid crystal layer from the surface of the first substrate on the liquid crystal layer side.
摘要翻译：在第一基板和第二基板之间插入有蓝色相的液晶层的液晶显示装置中，设置在第一基板和第二基板之间的像素电极层（第一电极层）和公共电极层并且液晶层彼此不重叠。像素电极层被形成为覆盖从液晶层侧的第一基板的表面突出到液晶层的肋状的第一结构体的顶面和侧面。公共电极层被形成为覆盖从液晶层侧的第一基板的表面突出到液晶层的肋状的第二结构体的顶面和侧面。

10. 发明申请

US20100302492A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME 有权
标题翻译：液晶显示装置及其制造方法
公开(公告)号：US20100302492A1
公开(公告)日：2010-12-02
申请号：US12779604
申请日：2010-05-13
申请人： Daisuke KUBOTA , Akio YAMASHITA , Tetsuji ISHITANI , Tomohiro TAMURA
发明人： Daisuke KUBOTA , Akio YAMASHITA , Tetsuji ISHITANI , Tomohiro TAMURA
IPC分类号： G02F1/1333 , G02F1/1343 , H01L21/28
CPC分类号： G02F1/1343 , G02F1/133603 , G02F1/133707 , G02F1/134363 , G02F1/1345 , G02F2001/134372 , G02F2001/13793 , G02F2202/023 , G02F2202/103 , G02F2202/104 , G02F2202/105 , H01L27/1225 , H01L29/04 , H01L29/78696
摘要： A liquid crystal display device using a liquid crystal exhibiting a blue phase and having a novel structure, and a method for manufacturing the liquid crystal display device. A plurality of structure bodies (also referred to as ribs, protrusions, or projecting portions) are formed over the same substrate, and a pixel electrode and an electrode (a common electrode at a fixed potential) corresponding to the pixel electrode are formed thereover. An electric field is applied to the liquid crystal layer exhibiting a blue phase by using the pixel electrode that has an inclination and the electrode corresponding to the pixel electrode, which also has an inclination. A shorter distance between the adjacent structure bodies allows a strong electric field to be applied to the liquid crystal layer, which results in a reduction in power consumption for driving the liquid crystal.
摘要翻译：使用具有蓝相的液晶并具有新颖结构的液晶显示装置，以及液晶显示装置的制造方法。在同一基板上形成多个结构体（也称为肋，凸部或突出部），并且在其上形成像素电极和与像素电极对应的电极（固定电位的公共电极）。通过使用具有倾斜度的像素电极和对应于也具有倾斜度的像素电极的电极，向呈现蓝相的液晶层施加电场。相邻的结构体之间的较短的距离允许将强电场施加到液晶层，这导致用于驱动液晶的功耗的降低。

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