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1. 发明申请

US20130066321A1 ORTHOPAEDIC INSTRUMENT 审中-公开
标题翻译：仪器仪表
公开(公告)号：US20130066321A1
公开(公告)日：2013-03-14
申请号：US13582782
申请日：2011-01-21
申请人： Jurgen Mannss , Thorsten Burger
发明人： Jurgen Mannss , Thorsten Burger
IPC分类号： A61B17/58 , A61B17/56
CPC分类号： A61B17/1739 , A61B17/1746 , A61B17/1778 , A61B2034/108
摘要： A patient specific instrument for use in a ball and socket joint arthroplasty procedure, method of manufacture and method of use are described. The instrument comprises an attachment mechanism for attaching the instrument to the socket of the patient, which has at least first and second parts which can engage the rim of the socket of the patient. Each part is shaped, or can transform to a shape, to match the shape of a respective portion of the rim of the socket. A body bears at least one guide formation for guiding a component to be used in the arthroplasty procedure. The instrument includes a locking mechanism by which the body and attachment mechanism can be assembled in a unique configuration into the patient specific instrument. The patient specific instrument is attachable to the socket of the patient only at a single pre-planned position.
摘要翻译：描述了一种用于球窝联合关节置换手术，制造方法和使用方法的患者特定仪器。仪器包括用于将仪器附接到患者的插座的附接机构，其具有至少第一和第二部分，其可接合患者的插座的边缘。每个部件被成形或可以变形为形状以匹配插座的边缘的相应部分的形状。身体至少有一个引导构件用于引导在关节置换手术中使用的部件。该仪器包括锁定机构，通过该锁定机构，身体和附接机构可以以独特的构造组装到患者特定仪器中。患者专用仪器只能在单个预先计划的位置附接到患者的插座上。

2. 发明申请

US20110092858A1 SURGICAL APPARATUS AND PROCEDURE 有权
标题翻译：外科手术和手术
公开(公告)号：US20110092858A1
公开(公告)日：2011-04-21
申请号：US12919839
申请日：2009-02-26
申请人： Thorsten Burger , Frank Foley , Michal Slomczykowski
发明人： Thorsten Burger , Frank Foley , Michal Slomczykowski
IPC分类号： A61B5/103
CPC分类号： A61B34/10 , A61B34/20 , A61B2090/061
摘要： A computer assisted surgery method and apparatus for determining a change in a property of a joint of a patient caused by an arthroplasty procedure is described. The relative position of a first bone and a second bone of the joint is determined with the joint in a first position. The position of a pre-operative center of motion of the joint relative to the first bone is determined. The position of the second bone relative to the pre-operative center of motion is determined using the relative position of the first and second bones. The position of a post-operative center of motion resulting from a prosthetic component to be used in the joint is determined. The position of the second bone relative to the post-operative center of motion is determined. Any change in the property of the joint. is determined from the difference between the position of the second bone relative to the pre-operative center of motion and the position of the second bone relative to the post-operative center of motion.
摘要翻译：描述了一种计算机辅助手术方法和装置，用于确定由关节成形术程序引起的患者关节的变化的变化。用关节在第一位置确定关节的第一骨和第二骨的相对位置。确定关节相对于第一骨骼的手术前运动中心的位置。使用第一和第二骨骼的相对位置确定第二骨骼相对于手术前运动中心的位置。确定由在关节中使用的假体部件产生的手术后运动中心的位置。确定第二骨相对于手术后运动中心的位置。联合财产的任何变化。由第二骨骼相对于手术前运动中心的位置与第二骨骼相对于手术后运动中心的位置之间的差确定。

3. 发明申请

US20080269596A1 Orthpaedic Monitoring Systems, Methods, Implants and Instruments 审中-公开
标题翻译： Orthpaedic监测系统，方法，植入物和仪器
公开(公告)号：US20080269596A1
公开(公告)日：2008-10-30
申请号：US10598626
申请日：2005-03-10
申请人： Ian Revie , Alan Ashby , Thorsten Burger , Stefan Vilsmeier , Assaf Govari , Dudi Reznick , Pesach Susel , Avi Shalgi
发明人： Ian Revie , Alan Ashby , Thorsten Burger , Stefan Vilsmeier , Assaf Govari , Dudi Reznick , Pesach Susel , Avi Shalgi
IPC分类号： A61B5/00 , G06Q50/00 , A61B19/00
CPC分类号： G06Q10/087 , A61B6/12 , A61B6/4007 , A61B6/4266 , A61B34/10 , A61B34/20 , A61B34/25 , A61B90/36 , A61B90/361 , A61B90/39 , A61B2017/00716 , A61B2017/0268 , A61B2034/102 , A61B2034/105 , A61B2034/108 , A61B2034/2051 , A61B2034/2055 , A61B2034/2072 , A61B2034/252 , A61B2034/254 , A61B2034/256 , A61B2090/0818 , A61B2090/364 , A61B2090/365 , A61B2090/367 , A61B2090/376 , A61B2090/3916 , A61B2090/3954 , A61B2090/3975 , A61B2090/3987 , A61B2090/502 , A61F2/34 , A61F2/36 , A61F2/4603 , A61F2/4607 , A61F2/4609 , A61F2/461 , A61F2002/3008 , A61F2002/3067 , A61F2002/3895 , A61F2002/4632 , A61F2250/0002 , A61F2250/0098
摘要： Orthopaedic operating systems, operating rooms, computer aided surgical methods, trackable implants, instruments and surgical planning and IGS software applications are described. The integrated surgical system is for use in an orthopaedic operating room to enable a surgeon to carry out a computer aided surgical procedure on a subject. A subject support, wireless magnetic tracking system, registration system, at least a first display device, a control system and a surgeon interface operable by the surgeon to control operation of the plurality of parts of the integrated surgical system are provided. The method comprises determining the position of at least a first marker being wirelessly tracked by a wireless magnetic tracking system, registering the position of the body part of the subject with an image of the body part of the subject, displaying a registered image of the body part of the subject and at least an image representative of an implant, and receiving a command from a surgeon interface operable by the surgeon.
摘要翻译：描述了矫形手术系统，手术室，计算机辅助手术方法，可追踪植入物，器械和手术计划以及IGS软件应用。整合手术系统用于矫形手术室，以使外科医生能够对受试者执行计算机辅助外科手术。提供了一种受试者支持，无线磁跟踪系统，注册系统，至少第一显示设备，控制系统和外科医生接口，其可由外科医生操作以控制整合手术系统的多个部分的操作。该方法包括确定由无线磁跟踪系统无线跟踪的至少第一标记的位置，用被摄体的身体部位的图像记录被检体的身体部位的位置，显示身体的登记图像主题的一部分和至少一个代表植入物的图像，以及从外科医生接受来自外科医生接口的命令。

4. 发明申请

US20050119832A1 Computer system and method for calculating adme properties 失效
标题翻译：计算机系统和计算adme属性的方法
公开(公告)号：US20050119832A1
公开(公告)日：2005-06-02
申请号：US10497759
申请日：2002-11-25
申请人： Walter Schmitt , Jorg Keldenich , Jannis Batoulis , Michael Beck , Roger-Michael Brunne , Thorsten Burger , Thorsten Potter , Felix Reichel , Stefan Willmann
发明人： Walter Schmitt , Jorg Keldenich , Jannis Batoulis , Michael Beck , Roger-Michael Brunne , Thorsten Burger , Thorsten Potter , Felix Reichel , Stefan Willmann
IPC分类号： G01N33/48 , B01J19/00 , G01N20060101 , G01N31/00 , G01N33/50 , G06F17/00 , G06F19/00 , G06F19/12 , G06F19/16 , G06N3/00
CPC分类号： G06F19/704 , G06F19/705
摘要： The invention relates to a computer system and a method for calculating an ADME property of a substance, which comprises the following steps: a. input of molecular properties of said substance into a biophysical model, whereby said biophysical model describes a correlation between the molecular properties and the ADME property and b. output of the ADME property.
摘要翻译：本发明涉及一种用于计算物质的ADME性质的计算机系统和方法，包括以下步骤：a。将所述物质的分子性质输入到生物物理模型中，其中所述生物物理模型描述了分子性质和ADME性质之间的相关性。输出ADME属性。

5. 发明授权

US06853857B2 Method, device and computer program for determining the blood flow in a tissue or organ region 有权
标题翻译：用于确定组织或器官区域中的血流的方法，装置和计算机程序
公开(公告)号：US06853857B2
公开(公告)日：2005-02-08
申请号：US10134650
申请日：2002-04-30
申请人： Ulrich J. Pfeiffer , Thorsten Burger , Andreas Becker
发明人： Ulrich J. Pfeiffer , Thorsten Burger , Andreas Becker
IPC分类号： A61B5/00 , A61B5/026 , A61B5/0275 , A61B6/00
CPC分类号： A61B5/0275 , A61B5/0059 , A61B5/0261
摘要： In a method, a device and a computer program for determining the blood flow in a tissue or organ region, the fluorescence intensity of an exogenous chromophore is measured as a function of time in the tissue region to be examined and from this the permeation rate of the chromophore is calculated, from which the blood flow can be derived.
摘要翻译：在一种用于确定组织或器官区域中的血液流动的装置和计算机程序中，测量外源发色团的荧光强度作为待检查组织区域中时间的函数，并且从该渗透速率计算发色团，从中可以导出血流。

6. 发明授权

US06394961B1 Method to increase transpulmonary thermodilution cardiac output accuracy by use of extravascular thermovolume to control the amount of thermal indicator 有权
标题翻译：通过使用血管外热血流量来控制热指示剂的量来增加肺内热稀释心输出量的方法
公开(公告)号：US06394961B1
公开(公告)日：2002-05-28
申请号：US09697600
申请日：2000-10-27
申请人： Ulrich J. Pfeiffer , Thorsten Burger
发明人： Ulrich J. Pfeiffer , Thorsten Burger
IPC分类号： A61B502
CPC分类号： A61B5/028 , A61B5/029
摘要： The present invention relates to a method for determining the cardiac output of a subject by thermodilution measurements by providing a predetermined amount of thermal indicator in a blood vessel with the thermal indicator having a temperature different from the temperature of subject's blood, thus exhibiting an indicator temperature difference. By measuring the temperature of subject's blood at a second place downstream the cardiac output (CO) and the extravascular thermovolume can be determined as a function of the time for the thermodilution curve. As a function of the thermodilution curve the measurements of the amount of thermal indicator and/or thermal indicator volume temperature difference are adjusted to provide a more accurate determination of cardiac output.
摘要翻译：本发明涉及通过在血管中提供预定量的热指示剂来测定受试者的心输出量的方法，所述热指示器的温度不同于受试者血液的温度，因此显示指示剂温度区别。通过测量心输出量（CO）下游第二个位置处的受试者血液的温度，并且可以将血管外热血流量确定为热稀释曲线的时间的函数。作为热稀释曲线的函数，调节热指示剂量和/或热指示器体积温度差的测量值以提供更准确的心输出量测定。

7. 发明申请

US20120271613A1 INTRA-OPERATIVE SURGICAL PLAN CHANGING 有权
标题翻译：手术方案改变
公开(公告)号：US20120271613A1
公开(公告)日：2012-10-25
申请号：US13503253
申请日：2010-10-20
申请人： Alan Ashby , Harald Bornfleth , Thorsten Burger
发明人： Alan Ashby , Harald Bornfleth , Thorsten Burger
IPC分类号： G06G7/60
CPC分类号： G06F19/321 , G06F19/00
摘要： A system and computer implemented method for use in determining the deviation-of an intra-operative position of an orthopaedic implant from a planned position is described. The position of the orthopaedic implant in the bone is defined by a plurality of implant position parameters. The distance of a plurality of anatomical features in a three dimensional model of the surface of the bone relative to a model of the implant at a first position is calculated. The first position corresponds to a first set of values for the implant position parameters. The distance of the plurality of anatomical features to a model of the implant at a second position in the bone is calculated. The second position corresponds to a second set of values for the implant position parameters, and the second position is different to the first position.
摘要翻译：描述了一种用于确定整形外科植入物的术中位置与计划位置的偏差的系统和计算机实现的方法。骨骼植入物在骨骼中的位置由多个植入位置参数限定。计算骨骼表面的三维模型中的多个解剖特征相对于在第一位置处的植入物的模型的距离。第一位置对应于植入位置参数的第一组值。计算多个解剖特征与在骨骼中的第二位置处的植入物的模型的距离。第二位置对应于植入位置参数的第二组值，而第二位置与第一位置不同。

8. 发明授权

US07314449B2 Apparatus for determining cardiovascular parameters 失效
标题翻译：用于确定心血管参数的装置
公开(公告)号：US07314449B2
公开(公告)日：2008-01-01
申请号：US10743515
申请日：2003-12-22
申请人： Ulrich J. Pfeiffer , Thorsten Burger
发明人： Ulrich J. Pfeiffer , Thorsten Burger
IPC分类号： A61B5/02
CPC分类号： A61B5/0205 , A61B5/02028 , A61B5/02108 , A61B5/02152 , A61B5/1135
摘要： An apparatus that continuously monitors the arterial pressure measured by a pressure sensor in an artery, which pressure is regarded as the reading Pao that approximately corresponds to the aortal pressure. In principle, the arterial pressure can be measured in the aorta, near the aorta, or in the arterial tree. To provide a second reading, the apparatus, via the input channel, continuously monitors the central venous pressure (CVP), which is regarded as the reading PIT that approximately corresponds to the intrathoracic pressure (ITP). The third reading is provided via the input channel as a reading Z which expresses the thoracic compliance. Via known algorithms of the pulse contour analysis, the apparatus calculates the stroke volume variation, using as the determining pressure the transmural pressure which is calculated according to the formula Ptransmural=Pao−f(C)*PIT The cardiac volume responsiveness indicator (CVRI) is calculated for mechanical positive respiration according to the formula CVRI=k*(SVV/ΔCVP) or for spontaneous breathing according to the formula CVRI=l−m*(ΔCVP/SVV).
摘要翻译：一种连续监测动脉压力传感器测量的动脉压的装置，该压力被认为是大致对应于主动脉压的读数Pao。原则上，可以在主动脉，主动脉附近或动脉树中测量动脉压。为了提供二读，该装置经由输入通道连续监测中心静脉压（CVP），其被认为是大致对应于胸内压（ITP）的读数PIT。通过输入通道提供三读作为表达胸部顺应性的读数Z。通过脉冲轮廓分析的已知算法，该装置计算行程体积变化，使用根据公式<？in-line-formula description =“In-line Formulas”end =“ 铅“？> Ptransmural = Pao-f（C）* PIT <？in-line-formula description =”In-line Formulas“end =”tail“？>计算心脏体积反应性指标（CVRI），用于机械正呼吸根据公式<？in-line-formula description =“In-line Formulas”end =“lead”？> CVRI = k *（SVV / DeltaCVP）<？in-line-formula description =“In-line Formulas” end =“tail”？>或用于根据公式的自发呼吸<？in-line-formula description =“In-line Formulas”end =“lead”？> CVRI = lm *（DeltaCVP / SVV）<？in -line-formula description =“内联公式”end =“tail”？>

9. 发明申请

US20060084890A1 Method and apparatus for performing a computer-assisted orthopaedic procedure 有权
公开(公告)号：US20060084890A1
公开(公告)日：2006-04-20
申请号：US10956181
申请日：2004-09-30
申请人： D. Block , Thorsten Burger , Francois Urvoy , Magnus Flett , Michal Slomczykowski , Marcellino Maheson , Roger Oakeshott , Alec Birkbeck
发明人： D. Block , Thorsten Burger , Francois Urvoy , Magnus Flett , Michal Slomczykowski , Marcellino Maheson , Roger Oakeshott , Alec Birkbeck
IPC分类号： A61B5/103
CPC分类号： A61B17/864 , A61B17/1742 , A61B34/20 , A61B2010/0258 , A61B2034/2055 , A61B2090/3916 , A61B2090/3983
摘要： A method of performing a computer-assisted orthopaedic procedure includes securing a sensor support instrument to the patient's bone. A number of sensors are secured to the support instrument. A computer-assisted orthopaedic surgical instrument is also disclosed.

10. 发明授权

US09737369B2 Surgical apparatus and procedure 有权
公开(公告)号：US09737369B2
公开(公告)日：2017-08-22
申请号：US12919839
申请日：2009-02-26
申请人： Thorsten Burger , Frank Foley , Michal Slomczykowski
发明人： Thorsten Burger , Frank Foley , Michal Slomczykowski
IPC分类号： A61B5/103 , A61B34/10 , A61B34/20 , A61B90/00
CPC分类号： A61B34/10 , A61B34/20 , A61B2090/061
摘要： A computer assisted surgery method and apparatus for determining a change in a property of a joint of a patient caused by an arthroplasty procedure is described. The relative position of a first bone and a second bone of the joint is determined with the joint in a first position. The position of a pre-operative center of motion of the joint relative to the first bone is determined. The position of the second bone relative to the pre-operative center of motion is determined using the relative position of the first and second bones. The position of a post-operative center of motion resulting from a prosthetic component to be used in the joint is determined. The position of the second bone relative to the post-operative center of motion is determined. Any change in the property of the joint. is determined from the difference between the position of the second bone relative to the pre-operative center of motion and the position of the second bone relative to the post-operative center of motion.

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