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1. 发明授权

US08039524B2 Reagent and method for providing coatings on surfaces 失效
标题翻译：用于在表面上提供涂层的试剂和方法
公开(公告)号：US08039524B2
公开(公告)日：2011-10-18
申请号：US12783907
申请日：2010-05-20
申请人： Ralph A. Chappa , Sean M. Stucke , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Pam Read, legal representative , Dale G. Swan , Peter H. Duquette
发明人： Ralph A. Chappa , Sean M. Stucke , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Dale G. Swan , Peter H. Duquette
IPC分类号： C08F2/50
CPC分类号： B82Y30/00 , A61L27/34 , C09D4/00 , Y10S522/904 , Y10T428/249991 , Y10T428/249992 , C08F220/56 , C08F220/54
摘要： A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate. The method includes the steps of a) providing a porous support surface, b) providing a nonpolymeric grafting reagent comprising a photoinitator group, c) providing one or more polymerizable monomers adapted to be contacted with the surface, in the presence of the grafting reagent, and to be polymerized upon activation of the photoinitiator; and d) applying the grafting reagent and monomer(s) to the surface in a manner, and under conditions, suitable to coat the surface with the grafting reagent and to cause the polymerization of monomers to the surface upon activation of the grafting reagent.
摘要翻译：以提供和/或保留表面的所需性质（例如孔隙率）的方式使用试剂在支撑表面上，特别是多孔载体表面上形成聚合物层的接枝试剂和相关方法。试剂和方法可用于提供具有所需性质的薄的，一致的，均匀的未交联的涂层，其具有预先形成的，特别是多孔的聚合物基材的表面。该方法包括以下步骤：a）提供多孔载体表面，b）提供包含光引发剂基团的非聚合物接枝剂，c）在接枝剂存在下，提供适于与表面接触的一种或多种可聚合单体，并在激活光引发剂时聚合; 和d）以接枝试剂的方式和条件下将接枝试剂和单体施用于表面，并且在接枝试剂活化时使单体聚合成表面。

2. 发明授权

US07087658B2 Water-soluble coating agents bearing initiator groups 有权
公开(公告)号：US07087658B2
公开(公告)日：2006-08-08
申请号：US10745080
申请日：2003-12-23
申请人： Dale G. Swan , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Ralph A. Chappa , Sean M. Stucke , Peter H. Duquette
发明人： Dale G. Swan , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Ralph A. Chappa , Sean M. Stucke , Peter H. Duquette
IPC分类号： C08F2/50 , C08J3/28 , C08J7/18
CPC分类号： C08J7/18 , A61L27/28 , A61L27/34 , A61L29/08 , A61L29/085 , A61L31/08 , A61L31/10 , A61L33/06 , A61L33/12 , B05D1/00 , B05D3/06 , B05D3/061 , B05D3/067 , B05D7/52 , G01N33/54353 , G01N33/54393 , Y10T428/31855
摘要： A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to the surface, as well as photoreactive groups adapted to remain unattached to the surface, and thus serve as photoinitiators for the activation of polymerizable compounds in order to form a polymer layer thereon. Also provided are coating agents, per se, as well as a method of using such agents and the resultant surfaces and devices fabricated therefrom.

3. 发明授权

US07071235B2 Latent reactive blood compatible agents 有权
公开(公告)号：US07071235B2
公开(公告)日：2006-07-04
申请号：US10422160
申请日：2003-04-24
申请人： Patrick E. Guire , Aron B. Anderson , Richard A. Amos , Terrence P. Everson , Peter H. Duquette
发明人： Patrick E. Guire , Aron B. Anderson , Richard A. Amos , Terrence P. Everson , Peter H. Duquette
IPC分类号： A01N35/00 , A01N37/00 , A61K31/74 , A61M25/00 , A61F2/06
CPC分类号： A61K31/12 , A61K31/74 , A61K47/6957 , A61L27/227 , A61L27/34 , A61L27/507 , A61L29/048 , A61L29/085 , A61L31/047 , A61L31/10 , A61L33/0011 , A61L33/0029 , A61L33/0082
摘要： A reagent and related method for use in passivating a biomaterial surface, the reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a spacer group linking the latent reactive group to the aliphatic acid in a manner that preserves the desired function of each group. Once bound to the surface, via the latent reactive group, the reagent presents the aliphatic acid to the physiological environment, in vivo, in a manner (e.g., concentration and orientation) sufficient to hold and orient albumin.

4. 发明授权

US06846788B2 Methods for removing silver-oxide 有权
标题翻译：去除氧化银的方法
公开(公告)号：US06846788B2
公开(公告)日：2005-01-25
申请号：US09876294
申请日：2001-06-07
申请人： Terrence P Everson , Bryan Anderson
发明人： Terrence P Everson , Bryan Anderson
IPC分类号： C11D3/00 , C11D7/26 , C11D7/36 , G03C11/00 , C11D17/00
CPC分类号： C11D7/262 , C11D3/0042 , C11D7/261 , C11D7/264 , C11D7/268 , C11D7/36 , G03C11/005
摘要： The present invention is directed to compositions for removing silver soil from the surface of objects. These compositions contain a reducing agent, and an alkaline source, and may optionally contain various other components including a chelating agent, cleaning agent, filler, an anti-corrosion agent, a defoaming agent, an odorant, a dye, an antioxidant, or a bleaching agent. Methods of using the compositions are also disclosed, wherein the object to be cleaned is contacted with the composition and the object is then washed with an aqueous solution.
摘要翻译：本发明涉及从物体表面除去银土的组合物。这些组合物含有还原剂和碱源，并且可任选地含有各种其它组分，包括螯合剂，清洁剂，填料，防腐蚀剂，消泡剂，气味剂，染料，抗氧化剂或漂白剂。还公开了使用组合物的方法，其中待清洁的物体与组合物接触，然后用水溶液洗涤物体。

5. 发明授权

US06812202B2 Detergent composition and method for removing soil 有权
标题翻译：洗涤剂组合物和去除土壤的方法
公开(公告)号：US06812202B2
公开(公告)日：2004-11-02
申请号：US10716989
申请日：2003-11-18
申请人： Victor F. Man , Terrence P. Everson , Steven E. Lentsch
发明人： Victor F. Man , Terrence P. Everson , Steven E. Lentsch
IPC分类号： C11D182
CPC分类号： C11D3/044 , C11D1/662 , C11D1/82 , C11D1/825
摘要： The invention relates to a highly alkaline or mildly alkaline detergent composition having enhanced cleaning properties. The detergent combines a source of alkalinity and a blend of nonionic surfactants that enhances cleaning starchy soils. The blend of nonionic surfactants preferably includes an alkyl polyglycoside surfactant and a silicon surfactant having a hydrophobic silicon group and a pendant hydrophilic group. Preferably, the blend of nonionic surfactants includes a surfactant having a hydrophobic group and an ethylene oxide residue containing group and a polymer additive. A method for removing soil from an article is provided.
摘要翻译：本发明涉及具有增强的清洁性能的高碱性或弱碱性洗涤剂组合物。洗涤剂结合碱性源和非离子表面活性剂的混合物，其增强清洁淀粉质土壤。非离子表面活性剂的混合物优选包括烷基多糖苷表面活性剂和具有疏水性硅基团和侧基亲水基团的硅表面活性剂。优选地，非离子表面活性剂的共混物包括具有疏水基团和含环氧乙烷残基的基团的表面活性剂和聚合物添加剂。提供了从制品中去除土壤的方法。

6. 发明授权

US5714360A Photoactivatable water soluble cross-linking agents containing an onium group 失效
标题翻译：含有鎓基的可光活化的水溶性交联剂
公开(公告)号：US5714360A
公开(公告)日：1998-02-03
申请号：US552758
申请日：1995-11-03
申请人： Dale G. Swan , Richard A. Amos , Terrence P. Everson
发明人： Dale G. Swan , Richard A. Amos , Terrence P. Everson
IPC分类号： C12N11/06 , C07B61/00 , C07C45/63 , C07C225/16 , C07C309/14 , C07D295/10 , C07D295/112 , C07D487/18 , C07K17/06 , C08J3/24 , C09K3/00 , G01N33/543 , C12N11/00 , C07C49/76 , G01N33/549
CPC分类号： C07D295/112 , C07C225/16 , C07C309/14 , C07C45/63 , C07K17/06 , G01N33/54353 , Y10S530/81 , Y10S530/816
摘要： A chemical linking agent is formed of a di- or higher functional photoactivatable compound having at least one group that is charged under the conditions of use in order to provide improved water solubility. The linking agent contains two or more photoreactive groups in order to allow the agent to be used as a cross-linking agent in aqueous systems. The charged group can be provided by a radical that includes one or more salts of organic acids, onium compounds, or protonated amines, (and optionally one or more additional photoreactive groups) and the photoreactive groups can be provided by two or more radicals that include an aryl ketone. The onium compound can provide a quaternary ammonium, sulfonium or phosphonium group. A surface can be coated with a target molecule such as a synthetic polymer, carbohydrate, protein, lipid, nucleic acid, drug, vitamin, cofactor or dye by forming an aqueous solution of the linking agent and the target molecule, placing the solution in contact with the surface and activating the photoreactive groups of the linking agent to cross-link the target molecule to the surface.
摘要翻译：化学连接剂由具有至少一个在使用条件下带电的至少一个基团的二官能或更高官能的可光活化化合物形成，以提供改善的水溶性。连接剂含有两种或更多种光反应性基团，以使该试剂在水性体系中用作交联剂。带电基团可以由包括一种或多种有机酸，鎓化合物或质子化胺盐（以及任选的一种或多种另外的光反应性基团）的基团提供，并且光反应性基团可以由两个或更多个基团提供，所述基团包括芳基酮。鎓化合物可以提供季铵，锍或鏻基团。通过形成连接剂和目标分子的水溶液，可以用靶分子如合成聚合物，碳水化合物，蛋白质，脂质，核酸，药物，维生素，辅因子或染料涂覆表面，将溶液接触并且激活连接剂的光反应性基团以使靶分子与表面交联。

7. 发明授权

US07348055B2 Reagent and method for providing coatings on surfaces 有权
标题翻译：用于在表面上提供涂层的试剂和方法
公开(公告)号：US07348055B2
公开(公告)日：2008-03-25
申请号：US10028518
申请日：2001-12-21
申请人： Ralph A. Chappa , Sean M. Stucke , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Dale G. Swan , Peter H. Duquette
发明人： Ralph A. Chappa , Sean M. Stucke , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Dale G. Swan , Peter H. Duquette
IPC分类号： B32B27/00
CPC分类号： B82Y30/00 , A61L27/34 , C09D4/00 , Y10S522/904 , Y10T428/249991 , Y10T428/249992 , C08F220/56 , C08F220/54
摘要： A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate. The method includes the steps of a) providing a porous support surface, b) providing a nonpolymeric grafting reagent comprising a photoinitator group, c) providing one or more polymerizable monomers adapted to be contacted with the surface, in the presence of the grafting reagent, and to be polymerized upon activation of the photoinitiator; and d) applying the grafting reagent and monomer(s) to the surface in a manner, and under conditions, suitable to coat the surface with the grafting reagent and to cause the polymerization of monomers to the surface upon activation of the grafting reagent.
摘要翻译：以提供和/或保留表面的所需性质（例如孔隙率）的方式使用试剂在支撑表面上，特别是多孔载体表面上形成聚合物层的接枝试剂和相关方法。试剂和方法可用于提供具有所需性质的薄的，一致的，均匀的未交联的涂层，其具有预先形成的，特别是多孔的聚合物基材的表面。该方法包括以下步骤：a）提供多孔载体表面，b）提供包含光引发剂基团的非聚合物接枝剂，c）在接枝剂存在下，提供适于与表面接触的一种或多种可聚合单体，并在激活光引发剂时聚合; 和d）以接枝试剂的方式和条件下将接枝试剂和单体施用于表面，并且在接枝试剂活化时使单体聚合成表面。

8. 发明授权

US07056533B2 Medicament incorporation matrix 失效
公开(公告)号：US07056533B2
公开(公告)日：2006-06-06
申请号：US09901425
申请日：2001-07-09
申请人： Stephen J. Chudzik , Terrence P. Everson , Richard A. Amos
发明人： Stephen J. Chudzik , Terrence P. Everson , Richard A. Amos
IPC分类号： A61K9/14 , A61K47/30
CPC分类号： A61L31/145 , A61L27/34 , A61L27/52 , A61L27/54 , A61L29/085 , A61L31/10 , A61L31/16 , A61L2300/22 , A61L2300/232 , A61L2300/252 , A61L2300/258 , A61L2300/404 , A61L2300/406 , A61L2300/606 , Y10S514/944 , C08L71/02
摘要： A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a form that permits the medicament to be released from the matrix in a prolonged, controlled, predictable and effective manner in vivo. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, a photoderivatized monomer, and a hydrophilic monomer such as acrylamide.

9. 发明授权

US06773668B1 Detergent dispenser 有权
标题翻译：洗涤剂分配器
公开(公告)号：US06773668B1
公开(公告)日：2004-08-10
申请号：US09550428
申请日：2000-04-17
申请人： Terrence P. Everson , Lee M. Monsrud , Michael P. Kremer , Edward D. Sowle
发明人： Terrence P. Everson , Lee M. Monsrud , Michael P. Kremer , Edward D. Sowle
IPC分类号： A61L200
CPC分类号： A47L15/4436 , Y10T137/4891
摘要： A solid detergent dispenser for use with a dishwashing machine includes a chamber and a lid. The chamber is configured and arranged to receive a solid detergent having a particular composition. A water inlet receives water from a water source, and the water flows through a tunnel into the bottom of the chamber. The chamber is flooded with water from the bottom to ensure relatively constant erosion of the solid detergent, which ensures that a relatively constant concentration of the solid detergent is used in the dishwashing machine. A water outlet allows water to flow out of the chamber into the dishwashing machine. The water must flow into the chamber faster than it flows out of the chamber to ensure that the appropriate amount of dissolution of the solid detergent occurs. The only valve used in the preferred embodiment is a valve to control the amount of water flowing into the water inlet.
摘要翻译：用于洗碗机的固体洗涤剂分配器包括室和盖。腔室被配置和布置成接收具有特定组成的固体洗涤剂。水入口从水源接收水，水流过隧道进入室的底部。该室从底部充满水，以确保固体洗涤剂的相对恒定的侵蚀，这确保了在洗碗机中使用相对恒定浓度的固体洗涤剂。出水口允许水从腔室流出到洗碗机中。水必须比其流出室更快地流入室，以确保固体洗涤剂溶解的适量。在优选实施例中使用的唯一阀是用于控制流入入水口的水量的阀。

10. 发明授权

US06632291B2 Methods and compositions for cleaning, rinsing, and antimicrobial treatment of medical equipment 有权
标题翻译：用于医疗设备的清洁，冲洗和抗微生物治疗的方法和组合物
公开(公告)号：US06632291B2
公开(公告)日：2003-10-14
申请号：US09816695
申请日：2001-03-23
申请人： Reid Rabon , Sally K. Swart , Denise Chandler , Terrence P. Everson
发明人： Reid Rabon , Sally K. Swart , Denise Chandler , Terrence P. Everson
IPC分类号： B08B300
CPC分类号： A61L2/186 , A61L2202/24 , C11D1/62 , C11D3/062 , C11D3/10 , C11D3/323 , C11D3/3707 , C11D3/48
摘要： The present invention relates to methods for cleaning, rinsing, and/or antimicrobial treatment of medical carts, medical cages, and other medical instruments, devices or equipment. The method for cleaning employs a solid alkaline, for example a solid carbonate, cleaning composition for cleaning the medical cart, cage, instrument, device, or equipment. The method for rinsing employs a solid neutral or neutralizing rinse composition for rinsing the medical cart, cage, instrument, device, or equipment. The method for antimicrobial treatment employs a solid, for example a solid quaternary ammonium or solid halogen, antimicrobial composition, for antimicrobial treatment of the medical cart, cage, instrument, device, or equipment.
摘要翻译：本发明涉及用于清洁，漂洗和/或抗微生物治疗医疗车，医疗笼和其它医疗仪器，装置或设备的方法。清洁方法采用固体碱性物质，例如固体碳酸盐，用于清洁医疗车，笼，仪器，装置或设备的清洁组合物。漂洗方法采用固体中性或中和漂洗组合物，用于冲洗医疗车，笼，仪器，装置或设备。用于抗微生物处理的方法使用固体，例如固体季铵或固体卤素抗微生物组合物，用于医疗车，笼，仪器，装置或设备的抗微生物处理。

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