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1. 发明授权

US08012989B2 Substituted pyrimidine compounds and their utility as CETP inhibitors 有权
标题翻译：取代的嘧啶化合物及其作为CETP抑制剂的用途
公开(公告)号：US08012989B2
公开(公告)日：2011-09-06
申请号：US12815905
申请日：2010-06-15
申请人： Tadaaki Ohgiya , Toru Miura , Ayumu Okuda , Toshiharu Arai , Koichi Yamazaki , Taro Aoki , Katsutoshi Miyosawa , Haruki Shibata , Kimiyuki Shibuya
发明人： Tadaaki Ohgiya , Toru Miura , Ayumu Okuda , Toshiharu Arai , Koichi Yamazaki , Taro Aoki , Katsutoshi Miyosawa , Haruki Shibata , Kimiyuki Shibuya
IPC分类号： A61K31/505
CPC分类号： C07D401/12 , C07D403/12 , C07D471/04
摘要： A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halogen atom, a lower alkyl group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7 and R8 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group and the like, R9 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, R10 and R11 represent hydrogen atom, a lower alkyl group, a lower alkoxy group, a halo(lower alkyl) group and the like, and A represents a heterocyclic ring constituted by 6 to 10 atoms, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).
摘要翻译：由下列通式（I）表示的化合物，其中R 1，R 2，R 3，R 4和R 5表示氢原子，卤原子，低级烷基等，R 6表示烷基，环烷基等，R7和R8表示氢原子，低级烷基，（低级环烷基）（低级烷基）等，R9表示氢原子，卤素原子，低级烷氧基等，R10和R11表示氢原子，低级烷基，低级烷氧基，卤代（低级烷基）等，A表示6〜10个原子构成的杂环，对胆固醇酯转移蛋白（CETP）具有有效的抑制活性。

2. 发明授权

US08005424B2 Communication device and communication method of underwater vehicle 有权
标题翻译：水下航行器通信装置及通信方法
公开(公告)号：US08005424B2
公开(公告)日：2011-08-23
申请号：US11545552
申请日：2006-10-11
申请人： Hiroshi Yoshida , Taro Aoki , Katsuki Fujimoto , Osamu Numamoto
发明人： Hiroshi Yoshida , Taro Aoki , Katsuki Fujimoto , Osamu Numamoto
IPC分类号： H04B13/02
CPC分类号： H04B13/02 , Y10S367/904
摘要： The present invention provides a communication device and a communication method of an underwater vehicle, which use an electromagnetic field (electromagnetic wave), having a higher propagation speed than that of an acoustic wave, for communication between an underwater vehicle and a mother vessel or the like so as to allow real-time control of the underwater vehicle and the like and further to make the communication little sensitive to noise and the like. The communication device performs wireless communication between an underwater vehicle in water and an object on land or on water, and is configured to compress data to be transmitted and transmit/receive the compressed data by the use of a low-frequency electromagnetic field.
摘要翻译：本发明提供了一种水下航行器的通信装置和通信方法，其使用具有比声波更高的传播速度的电磁场（电磁波），用于水下航行器和母舰之间的通信，或者像是能够实现水下航行器等的实时控制，进一步使通信对噪声等几乎不敏感。通信装置在水中的水下车辆和陆上或水上的物体之间进行无线通信，并且被配置为压缩要发送的数据，并且通过使用低频电磁场来发送/接收压缩数据。

3. 发明申请

US20090001810A1 Power Unit of Underwater Vehicle 失效
标题翻译：水下车辆动力装置
公开(公告)号：US20090001810A1
公开(公告)日：2009-01-01
申请号：US11770053
申请日：2007-06-28
申请人： Hiroshi YOSHIDA , Taro Aoki , Fumihiko Endo , Takayoshi Watanabe , Katsuki Fujimoto , Osamu Numamoto
发明人： Hiroshi YOSHIDA , Taro Aoki , Fumihiko Endo , Takayoshi Watanabe , Katsuki Fujimoto , Osamu Numamoto
IPC分类号： B60L9/00 , B63G8/42
CPC分类号： B63H21/17 , B63G8/08 , B63G8/42
摘要： The present invention provides a power unit of an underwater vehicle, which allows reduction in size and weight of a transformer for stepping down a power voltage of a power supply to increase a loading amount of a variety of devices with respect to the underwater vehicle, so as to obtain a favorable operating environment. The power unit is connected to the power supply through a cable and receives power through the cable. Further, the power unit comprises an electronic transformer having: a rectifier for rectifying a high-voltage alternate current power of the power supply into a direct current; a high-frequency converter for converting an output of the rectifier into a high-frequency alternate current; a transformer for stepping down an output voltage of the high-frequency converter; a rectifier for rectifying an output of the transformer into a direct current; and a control circuit for controlling the high-frequency converter.
摘要翻译：本发明提供一种水下航行器的动力单元，其能够减小变压器的尺寸和重量，以降低电源的电源电压，从而增加各种装置相对于水下车辆的负载量，因此以获得有利的经营环境。电源单元通过电缆连接到电源，并通过电缆接收电源。此外，电力单元包括电子变压器，其具有：整流器，用于将电源的高压交流电力整流为直流电; 用于将整流器的输出转换成高频交流的高频转换器; 用于降低高频转换器的输出电压的变压器; 用于将变压器的输出整流为直流电的整流器; 以及用于控制高频转换器的控制电路。

4. 发明申请

US20080305369A1 Fuel Cell Operating Method and Apparatus For the Same 审中-公开
标题翻译：燃料电池的操作方法和装置
公开(公告)号：US20080305369A1
公开(公告)日：2008-12-11
申请号：US11630107
申请日：2006-02-07
申请人： Tatsuya Muraki , Katuhiro Terao , Tetsunari Nakamura , Taro Aoki , Tadahiro Hyakudome , Syojiro Ishibashi
发明人： Tatsuya Muraki , Katuhiro Terao , Tetsunari Nakamura , Taro Aoki , Tadahiro Hyakudome , Syojiro Ishibashi
IPC分类号： H01M8/00
CPC分类号： H01M8/04201 , C01B3/0031 , C01B13/0259 , F17C11/00 , F17C11/005 , H01M8/04089 , H01M8/04216 , H01M8/065 , Y02E60/321 , Y02E60/327 , Y02P20/129
摘要： There is a problem in that a gas pressure in an oxygen container of an oxygen supply device is high, thereby causing a mounting cost for charging gas into the oxygen container. Further, there is also a problem in terms of safety at a time of operation. A hydrogen occluding alloy container (5) containing a hydrogen occluding alloy which occludes the hydrogen is used as a hydrogen resource, an oxygen storage container (4b) containing an oxygen adsorbing material (23) that adsorbs the oxygen is used as an oxygen resource, a hydrogen heating means (11a) for heating the hydrogen occluding alloy container (5) and an oxygen heating means (11b) for heating the oxygen storage container (4b) are provided, and the hydrogen occluding alloy container (5) is heated by the hydrogen heating means (11a) and an excess exhaust heat obtained after the hydrogen occluded in the hydrogen occluding alloy is emitted is guided to the oxygen heating means (11b) to heat the oxygen storage container (4b), thereby promoting removal of the oxygen from the oxygen adsorbing material (23) and allowing a pressure of an oxygen gas to rise to supply the hydrogen and the oxygen to the fuel cell (1).
摘要翻译：存在供氧装置的氧气容器中的气体压力高的问题，从而导致将气体充入氧气容器中的安装成本。此外，在操作时也存在安全性方面的问题。使用含有吸藏氢的吸氢合金的吸氢合金容器（5）作为氢源，使用含有吸附氧的氧吸附材料（23）的储氧容器（4b）作为氧源，设置用于加热吸氢合金容器（5）的氢气加热装置（11a）和用于加热储氧容器（4b）的氧气加热装置（11b），并且吸氢合金容器（5）被加热氢气加热装置（11a）和在吸留在吸氢合金中的氢气之后获得的过量排气被引导到氧气加热装置（11b）以加热储氧容器（4b），从而促进从氧气氧吸附材料（23），并允许氧气压力升高以向燃料电池（1）供应氢气和氧气。

5. 发明申请

US20060111437A1 Hyperlipemia therapeutic agent 有权
标题翻译：高脂血症治疗剂
公开(公告)号：US20060111437A1
公开(公告)日：2006-05-25
申请号：US11293217
申请日：2005-12-05
申请人： Taro Aoki , Junji Yamaguchi , Yusuke Sasaki
发明人： Taro Aoki , Junji Yamaguchi , Yusuke Sasaki
IPC分类号： A61K31/366 , A61K31/22 , A61K31/202
CPC分类号： A61K31/47 , A61K31/202 , A61K2300/00
摘要： The present invention relates to a hyperlipemia therapeutic agent comprising pitavastatins and eicosapentaenoic acid or an ester derivative thereof as effective ingredients. According to the present invention, a type IIb and type IV hyperlipemia therapeutic agent having an excellent effect of lowering the cholesterol and triglyceride in blood is provided.
摘要翻译：本发明涉及包含匹伐他汀和二十碳五烯酸或其酯衍生物作为有效成分的高脂血症治疗剂。根据本发明，提供了具有降低血液中的胆固醇和甘油三酯的优异效果的IIb型和IV型高脂血症治疗剂。

6. 发明申请

US20060046996A1 Method for treating hyperlipidemia 审中-公开
标题翻译：治疗高脂血症的方法
公开(公告)号：US20060046996A1
公开(公告)日：2006-03-02
申请号：US10997878
申请日：2004-11-29
申请人： Taro Aoki , Hiroyuki Yamazaki , Takashi Maejima
发明人： Taro Aoki , Hiroyuki Yamazaki , Takashi Maejima
IPC分类号： A61K31/47 , A61K31/366 , A61K31/225
CPC分类号： A61K31/397 , A61K31/47 , A61K31/4709 , A61K2300/00
摘要： Provided is a method for treating hyperlipidemia or hypercholesterolemia, which comprises administering effective doses of ezetimibe and pitavastatin or a salt or lactone derivative thereof.
摘要翻译：提供治疗高脂血症或高胆固醇血症的方法，其包括施用有效剂量的依泽替米贝和匹伐他汀或其盐或内酯衍生物。

7. 发明授权

US07776881B2 Hyperlipemia therapeutic agent 有权
标题翻译：高脂血症治疗剂
公开(公告)号：US07776881B2
公开(公告)日：2010-08-17
申请号：US11293217
申请日：2005-12-05
申请人： Taro Aoki , Junji Yamaguchi , Yusuke Sasaki
发明人： Taro Aoki , Junji Yamaguchi , Yusuke Sasaki
IPC分类号： A61K31/47 , A61K31/22 , A61K31/20
CPC分类号： A61K31/47 , A61K31/202 , A61K2300/00
摘要： A hypertriglyceridemia therapeutic agent made up of a synergistically effective blood-triglyceride decreasing amount of a combination of a pitavastatin and eicosapentaenoic acid (EPA), or an ester thereof.
摘要翻译：一种高甘油三酯血症治疗剂，其由协同有效的血甘油三酯减少量的匹伐他汀和二十碳五烯酸（EPA）的组合或其酯组成。

8. 发明授权

US07692328B2 Power unit of underwater vehicle 失效
标题翻译：水下车辆动力装置
公开(公告)号：US07692328B2
公开(公告)日：2010-04-06
申请号：US11770053
申请日：2007-06-28
申请人： Hiroshi Yoshida , Taro Aoki , Fumihiko Endo , Takayoshi Watanabe , Katsuki Fujimoto , Osamu Numamoto
发明人： Hiroshi Yoshida , Taro Aoki , Fumihiko Endo , Takayoshi Watanabe , Katsuki Fujimoto , Osamu Numamoto
IPC分类号： B60L1/00
CPC分类号： B63H21/17 , B63G8/08 , B63G8/42
摘要： The present invention provides a power unit of an underwater vehicle, which allows reduction in size and weight of a transformer for stepping down a power voltage of a power supply to increase a loading amount of a variety of devices with respect to the underwater vehicle, so as to obtain a favorable operating environment. The power unit is connected to the power supply through a cable and receives power through the cable. Further, the power unit comprises an electronic transformer having: a rectifier for rectifying a high-voltage alternate current power of the power supply into a direct current; a high-frequency converter for converting an output of the rectifier into a high-frequency alternate current; a transformer for stepping down an output voltage of the high-frequency converter; a rectifier for rectifying an output of the transformer into a direct current; and a control circuit for controlling the high-frequency converter.
摘要翻译：本发明提供一种水下航行器的动力单元，其能够减小变压器的尺寸和重量，以降低电源的电源电压，从而增加各种装置相对于水下车辆的负载量，因此以获得有利的经营环境。电源单元通过电缆连接到电源，并通过电缆接收电源。此外，电力单元包括电子变压器，其具有：整流器，用于将电源的高压交流电力整流为直流电; 用于将整流器的输出转换成高频交流的高频转换器; 用于降低高频转换器的输出电压的变压器; 用于将变压器的输出整流为直流电的整流器; 以及用于控制高频转换器的控制电路。

9. 发明授权

US07598233B2 Method for treating thrombosis 有权
标题翻译：治疗血栓形成的方法
公开(公告)号：US07598233B2
公开(公告)日：2009-10-06
申请号：US11158080
申请日：2005-06-22
申请人： Toru Yokoyama , Taro Aoki
发明人： Toru Yokoyama , Taro Aoki
IPC分类号： A61K31/60 , A61K31/44 , A01N37/36 , A01N43/42
CPC分类号： A61K31/22 , A61K31/36 , A61K31/60 , A61K2300/00
摘要： This invention relates to a method for treating thrombosis by combined administration of a pitavastatin with aspirin.
摘要翻译：本发明涉及通过联合给予匹伐他汀与阿司匹林来治疗血栓形成的方法。

10. 发明申请

US20090082352A1 NOVEL PYRIMIDINE COMPOUND HAVING DIBENZYLAMINE STRUCTURE AND MEDICAMENT COMPRISING THE SAME 有权
标题翻译：具有二苯胺结构的新型吡咯烷酮化合物和包含其的药物
公开(公告)号：US20090082352A1
公开(公告)日：2009-03-26
申请号：US12100831
申请日：2008-04-10
申请人： Tadaaki OHGIYA , Toru MIURA , Ayumu OKUDA , Toshiharu ARAI , Koichi YAMAZAKI , Taro AOKI , Katsutoshi MIYOSAWA , Haruki SHIBATA , Kimiyuki SHIBUYA
发明人： Tadaaki OHGIYA , Toru MIURA , Ayumu OKUDA , Toshiharu ARAI , Koichi YAMAZAKI , Taro AOKI , Katsutoshi MIYOSAWA , Haruki SHIBATA , Kimiyuki SHIBUYA
IPC分类号： A61K31/5377 , C07D239/42 , A61K31/505
CPC分类号： C07D239/42 , C07D239/47 , C07D401/12 , C07D403/12 , C07D413/12
摘要： A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halo(lower alkyl) group, cyano group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7, R8, R9 and R10 represent hydrogen atom, a halogen atom, a lower alkyl group, a halo(lower alkyl) group and the like, R11 and R12 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl) (lower alkyl) group and the like, and R13 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).
摘要翻译：由以下通式（I）表示的化合物，其中R 1，R 2，R 3，R 4和R 5表示氢原子，卤代（低级烷基）基，氰基等，R 6表示烷基，环烷基和 R 7，R 8，R 9和R 10表示氢原子，卤素原子，低级烷基，卤代（低级烷基）等，R 11和R 12表示氢原子，低级烷基，（低级环烷基）（低级烷基）等，R 13表示对胆固醇酯转移蛋白（CETP）具有强抑制活性的氢原子，卤素原子，低级烷氧基等。

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