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1. 发明专利

AP3578A PHARMACEUTICAL COMPOSITION COMPRISING DEFERASIROX 未知
公开(公告)号：AP3578A
公开(公告)日：2016-02-08
申请号：AP2013006785
申请日：2011-09-30
申请人： CIPLA LTD , TURNER CRAIG ROBERT
发明人： MALHOTRA GEENA , PURANDARE SHRINIVAS MADHUKAR
IPC分类号： A61K9/14 , A61K9/20 , A61K31/4196
摘要： The present invention relates to a pharmaceutical composition comprising deferasirox, a process for preparing such pharmaceutical composition, and its use in the treatment of chronic iron overload. The pharmaceutical composition comprises nanosized deferasirox having improved surface area and solubility. It also relates to a method for treatment of chronic iron overload which comprises administering a pharmaceutical composition comprising nanosized deferasirox.

2. 发明申请

WO2014135891A1 PHARMACEUTICAL COMPOSITIONS FOR RECTAL ADMINISTRATION 审中-公开
标题翻译：药物组合物的药物管理
公开(公告)号：WO2014135891A1
公开(公告)日：2014-09-12
申请号：PCT/GB2014/050678
申请日：2014-03-07
申请人： CIPLA LIMITED , TURNER, Craig Robert
发明人： PURANDARE, Shrinivas Madhukar , MALHOTRA, Geena
IPC分类号： A61K9/12 , A61K31/00
CPC分类号： C07H17/08 , A61K9/0031 , A61K9/122 , A61K9/124 , A61K31/351 , A61K31/7048 , A61K45/06 , A61M31/00 , A61K2300/00
摘要： The present invention relates to pharmaceutical compositions for rectal administration comprising fidaxomicin and to a process for preparing the pharmaceutical compositions for rectal administration. The invention also relates to an aerosol canister comprising a foamable pharmaceutical composition comprising fidaxomicin for rectal administration and to the treatment or maintenance of remission of infections such as diarrhoea caused by Clostridium difficile ..
摘要翻译：本发明涉及包含fidaxomicin的直肠给药用药物组合物及其制备用于直肠给药的药物组合物的方法。本发明还涉及一种气雾剂罐，其包含可发泡药物组合物，其包含用于直肠给药的fidaxomicin和用于治疗或维持诸如由艰难梭菌引起的腹泻等感染的缓解。

3. 发明申请

WO2014122436A1 TOPICAL PHARMACEUTICAL COMPOSITIONS COMPRISING MINOXIDIL 审中-公开
标题翻译：含有迷迭香的局部药物组合物
公开(公告)号：WO2014122436A1
公开(公告)日：2014-08-14
申请号：PCT/GB2014/050278
申请日：2014-01-31
申请人： CIPLA HOUSE , TURNER, Craig Robert
发明人： PURANDARE, Shrinivas Madhukar , MALHOTRA, Geena
IPC分类号： A61K9/00 , A61Q7/00 , A61K31/506
CPC分类号： A61K31/506 , A61K8/4953 , A61K9/0014 , A61K47/10 , A61Q7/00
摘要： A topical pharmaceutical composition comprising minoxidil and at least one or more pharmaceutically acceptable excipients.
摘要翻译：包含米诺地尔和至少一种或多种药学上可接受的赋形剂的局部药物组合物。

4. 发明申请

WO2013153349A2 PHARMACEUTICAL COMPOSITION 审中-公开
标题翻译：药物组合物
公开(公告)号：WO2013153349A2
公开(公告)日：2013-10-17
申请号：PCT/GB2013/000161
申请日：2013-04-10
申请人： CIPLA LIMITED , TURNER, Craig Robert
发明人： PURANDARE, Shrinivas , MALHOTRA, Geena
IPC分类号： A61K9/00
CPC分类号： A61K31/58 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition comprising arformoterol and fluticasone furoate (preferably for once daily administration), to a process for preparing such a composition and to the use of such a composition for the treatment treatment and/or prevention of respiratory, inflammatory or obstructive airway disease.
摘要翻译：本发明涉及包含阿莫曲坦和糠酸氟替卡松（优选每天一次给药）的药物组合物，涉及制备这种组合物的方法以及用于治疗和/或预防呼吸，炎症或阻塞性气道疾病。

5. 发明申请

WO2012117227A8 RADIATION-INDUCED THICKENING AND RADIATION-INDUCED TRIGGERING FOR SET-ON-COMMAND SEALENT COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译：辐射引起的增稠和辐射引发的用于固定指令密封组合物的使用方法和使用方法
公开(公告)号：WO2012117227A8
公开(公告)日：2013-09-12
申请号：PCT/GB2012000215
申请日：2012-03-02
申请人： HALLIBURTON ENERGY SERV INC , LEWIS SAMUEL J , FUNKHOUSER GARY P , BADALAMENTI ANTHONY , RAO VIKRAM , MYERS DAVID F , GUPTA VIJAY , DAVIS JAMES L , LAMVIK MICHAEL , HOERTZ PAUL G , SOBY LYNN M , DUMMER ANDREW K , TURNER CRAIG ROBERT
发明人： LEWIS SAMUEL J , FUNKHOUSER GARY P , BADALAMENTI ANTHONY , RAO VIKRAM , MYERS DAVID F , GUPTA VIJAY , DAVIS JAMES L , LAMVIK MICHAEL , HOERTZ PAUL G , SOBY LYNN M , DUMMER ANDREW K
IPC分类号： C09K8/508 , C09K8/42
CPC分类号： C04B28/02 , C04B20/1033 , C09K8/426 , C09K8/467 , C09K2208/10 , C04B14/30 , C04B14/305 , C04B22/0013 , C04B24/2641 , C04B40/0204 , C04B2103/12 , C04B24/32 , C04B2103/22 , C04B24/2652 , C04B24/2623 , C04B24/2647
摘要： The present invention includes methods and compositions relating to the setting of fluids or slurries in a wellbore. In one embodiment, a method of isolating a portion a wellbore includes preparing a sealant composition having a fluid component, a polymeric additive constituent, and a set modifier component. The sealant composition is placed into a wellbore and subjected to ionizing radiation. The ionizing radiation can cause bonding between polymeric additive constituents and create a polymer matrix within the sealant composition that increases the mechanical strength of the sealant composition. The ionizing radiation also alters the set modifier component, triggering the thickening of the sealant composition.
摘要翻译：本发明包括与设置井眼中的流体或泥浆有关的方法和组合物。在一个实施方案中，分离井眼部分的方法包括制备具有流体组分，聚合物添加剂组分和凝固改性剂组分的密封剂组合物。将密封剂组合物置于井眼中并经受电离辐射。电离辐射可引起聚合物添加剂成分之间的键合并在密封剂组合物内产生增加密封剂组合物机械强度的聚合物基质。电离辐射也改变了凝固改性剂组分，引发了密封剂组合物的增稠。

6. 发明申请

WO2012117227A3 RADIATION-INDUCED THICKENING AND RADIATION-INDUCED TRIGGERING FOR SET-ON-COMMAND SEALENT COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译：放射诱导的增稠和辐射诱导的触发器，用于定位密封组合物和使用方法
公开(公告)号：WO2012117227A3
公开(公告)日：2013-05-30
申请号：PCT/GB2012000215
申请日：2012-03-02
申请人： HALLIBURTON ENERGY SERV INC , LEWIS SAMUEL J , FUNKHOUSER GARY P , BADALAMENTY ANTHONY , RAO VIKRAM , MYERS DAVID F , GUPTA VIJAY , DAVIS JAMES L , LAMVIK MICHAEL , HOERTZ PAUL G , SOBY LYNN M , DUMMER ANDREW K , TURNER CRAIG ROBERT
发明人： LEWIS SAMUEL J , FUNKHOUSER GARY P , BADALAMENTY ANTHONY , RAO VIKRAM , MYERS DAVID F , GUPTA VIJAY , DAVIS JAMES L , LAMVIK MICHAEL , HOERTZ PAUL G , SOBY LYNN M , DUMMER ANDREW K
IPC分类号： C09K8/508 , C09K8/42
CPC分类号： C04B28/02 , C04B20/1033 , C09K8/426 , C09K8/467 , C09K2208/10 , C04B14/30 , C04B14/305 , C04B22/0013 , C04B24/2641 , C04B40/0204 , C04B2103/12 , C04B24/32 , C04B2103/22 , C04B24/2652 , C04B24/2623 , C04B24/2647
摘要： The present invention includes methods and compositions relating to the setting of fluids or slurries in a wellbore. In one embodiment, a method of isolating a portion a wellbore includes preparing a sealant composition having a fluid component, a polymeric additive constituent, and a set modifier component. The sealant composition is placed into a wellbore and subjected to ionizing radiation. The ionizing radiation can cause bonding between polymeric additive constituents and create a polymer matrix within the sealant composition that increases the mechanical strength of the sealant composition. The ionizing radiation also alters the set modifier component, triggering the thickening of the sealant composition.
摘要翻译：本发明包括与井筒中的流体或浆料的凝固相关的方法和组合物。在一个实施方案中，分离井眼部分的方法包括制备具有流体组分的密封剂组合物，聚合物添加剂组分和组合改性剂组分。将密封剂组合物置于井眼中并进行电离辐射。电离辐射可引起聚合物添加剂组分之间的结合，并在密封剂组合物内产生增加密封剂组合物的机械强度的聚合物基质。电离辐射也改变固化改性剂组分，引起密封剂组合物的增稠。

7. 发明申请

WO2013068707A1 COMPOSITIONS AND METHODS RELATING TO THE STABILIZATION OF HYDROPHOBICALLY MODIFIED HYDROPHILIC POLYMER TREATMENT FLUIDS UNDER ALKALINE CONDITIONS 审中-公开
标题翻译：在碱性条件下稳定疏水改性的亲水性聚合物处理液的组合物和方法
公开(公告)号：WO2013068707A1
公开(公告)日：2013-05-16
申请号：PCT/GB2011/001660
申请日：2011-11-30
申请人： HALLIBURTON ENERGY SERVICES, INC , EOFF, Larry Steven , TURNER, Craig Robert
发明人： EOFF, Larry Steven , TURNER, Craig Robert
IPC分类号： C09K8/508
CPC分类号： C09K8/508
摘要： The present invention relates to methods and compositions for treating a water- and hydrocarbon-producing subterranean formation with a relative permeability modifier, and more specifically, to improved treatment fluids, methods for preparing treatment fluids, and methods for use thereof in a subterranean formation. Methods of the present invention comprise providing a treatment fluid comprising a relative permeability modifier, at least one surfactant, and an aqueous phase base fluid; and placing the treatment fluid in a subterranean formation. The relative permeability modifier comprises a hydrophobically modified hydrophilic polymer. The at least one surfactant is operable to maintain the relative permeability modifier in a dissolved state in the treatment fluid above a pH of about 8. The at least one surfactant may be an anionic curfactant.
摘要翻译：本发明涉及用相对渗透率调节剂处理产生水和烃的地下地层的方法和组合物，更具体地涉及改进的处理流体，制备处理流体的方法和方法用于其在地下地层中。本发明的方法包括提供包含相对渗透率调节剂，至少一种表面活性剂和水相基础流体的处理流体; 并将处理流体置于地下地层中。相对渗透性改性剂包含疏水改性的亲水性聚合物。所述至少一种表面活性剂可操作以将pH值约8以上的处理流体中的相对渗透性调节剂保持溶解状态。所述至少一种表面活性剂可以是阴离子表面活性剂。

8. 发明申请

WO2011151624A8 METHOD FOR MONOFLUOROMETHYLATION OF ORGANIC SUBSTRATES TO PREPARE BIOLOGICALLY ACTIVE ORGANIC COMPOUNDS 审中-公开
公开(公告)号：WO2011151624A8
公开(公告)日：2013-01-03
申请号：PCT/GB2011000834
申请日：2011-06-01
申请人： HOVIONE INT LTD , LEITAO EMILIA PERPETUA TAVARES , TURNER CRAIG ROBERT
发明人： LEITAO EMILIA PERPETUA TAVARES
IPC分类号： C07J31/00
CPC分类号： C07J31/006
摘要： The present invention describes a process for the preparation of monofluoromethylated organic biologically active compounds using monofluoromethylated reagents. Fluticasone Propionate and Fluticasone Furoate can be prepared using, for example, S-monofluoromethyl-S-phenyl-2,3,4,5- tetramethylphenylsulfonium tetrafluoroborate as monofluoromethylating reagent instead of bromofluoromethane.

9. 发明申请

WO2011138589A3 HIGH PRESSURE MANIFOLD TRAILER AND METHODS AND SYSTEMS EMPLOYING THE SAME 审中-公开
标题翻译：高压歧管拖车及其使用方法和系统
公开(公告)号：WO2011138589A3
公开(公告)日：2012-12-13
申请号：PCT/GB2011000695
申请日：2011-05-05
申请人： HALLIBURTON ENERGY SERV INC , NEAL KENNETH GREGORY , TURNER CRAIG ROBERT
发明人： NEAL KENNETH GREGORY
IPC分类号： E21B43/267
CPC分类号： E21B43/26 , B67D7/36 , B67D7/78 , E21B43/267 , Y10T137/0396 , Y10T137/2931
摘要： A method of servicing a subterranean formation with a servicing fluid, the method comprising providing a first component of the servicing fluid to a first high-pressure pump (50A) at a first pressure, providing a second component of the servicing fluid to a second high-pressure pump (50B) at a second pressure, increasing the pressure of the first component of the servicing fluid at the first high-pressure pump to a third pressure, wherein the third pressure is greater than the first pressure, increasing the pressure of the second component of the servicing fluid at the second high-pressure pump to a fourth pressure, wherein the fourth pressure is greater than the second pressure, communicating the first component of the servicing fluid to a high-pressure manifold (300), communicating the second component of the servicing fluid to the high-pressure manifold, communicating the first component of the servicing fluid from a first high-pressure manifold outlet to a wellhead (60) located at a wellbore, communicating the second component of the servicing fluid from a second high-pressure manifold outlet to the wellhead, and mixing the first component of the servicing fluid and the second component of the servicing fluid at the wellhead to form the servicing fluid.
摘要翻译：一种用维修流体维修地下地层的方法，所述方法包括在第一压力下向第一高压泵（50A）提供维修流体的第一部件，将维修流体的第二部件提供给第二高压压力泵（50B）在第二压力下将第一高压泵处的维修流体的第一部件的压力增加到第三压力，其中第三压力大于第一压力，增加压力将第二高压泵处的维修流体的第二部件提供到第四压力，其中第四压力大于第二压力，将维修流体的第一部件连通到高压歧管（300），将第二压力将维修流体的部件分配到高压歧管，将维修流体的第一部件从第一高压歧管出口连通到位于井眼，将维修流体的第二部件从第二高压歧管出口传送到井口，以及在井口处将维修流体的第一部件和维修流体的第二部件混合以形成维修流体。

10. 发明申请

WO2011117576A3 LAMINAR PHASE RING FOR FLUID TRANSPORT APPLICATIONS 审中-公开
标题翻译：用于流体运输应用的层间相环
公开(公告)号：WO2011117576A3
公开(公告)日：2012-12-13
申请号：PCT/GB2011000411
申请日：2011-03-23
申请人： HALLIBURTON ENERGY SERV INC , BRYANT JASON E , MCMECHAN CORINE L , WELTON THOMAS D , TALBOT MALCOLM S , TURNER CRAIG ROBERT
发明人： BRYANT JASON E , WELTON THOMAS D , TALBOT MALCOLM S , MCMECHAN DAVID EUGENE
IPC分类号： E21B21/08 , E21B33/068 , E21B43/267 , F17D1/00
CPC分类号： F17D1/005 , B01F5/0659 , E21B21/08 , E21B33/068 , E21B43/267 , Y10T137/0324
摘要： Methods for creating and using multi-phase fluid flows are disclosed. In one embodiment, such a method includes introducing an inner fluid into a tubular conduit. The method further includes introducing a ring fluid into the tubular conduit. In this embodiment, the ring fluid is disposed annularly between the inner fluid and the interior of the tubular conduit, and the flow of the ring fluid is laminar.
摘要翻译：公开了创建和使用多相流体流的方法。在一个实施例中，这种方法包括将内部流体引入管状导管中。该方法还包括将环形流体引入到管状导管中。在该实施例中，环形流体环形地设置在内部流体和管状导管的内部之间，并且环形流体的流动是层流的。

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