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    • 3. 发明申请
    • METHOD FOR REDUCING METAL ARTIFACT IN COMPUTED TOMOGRAPHY
    • 用于减少计算机图形学中的金属艺术的方法
    • US20160125625A1
    • 2016-05-05
    • US14748935
    • 2015-06-24
    • Sung Whan KIMKi Wan JEONChi Young AHN
    • Sung Whan KIMKi Wan JEONChi Young AHN
    • G06T11/00G06T5/00G06T7/00A61B6/03A61B6/00
    • G06T11/003A61B6/032A61B6/5205A61B6/5258A61B6/5264G06T5/001G06T7/0012G06T11/005G06T2207/10081G06T2207/30004G06T2210/41G06T2211/421
    • A method for reducing metal artifacts in computed tomography (CT) is disclosed. The method for reducing metal artifacts in CT includes: obtaining a sinogram reduced in size from an original sinogram; setting up a linear algebraic equation according to remaining data excluding data damaged by a metal based on the obtained sinogram; restoring a low-resolution image based on the set up linear algebraic equation; calculating a sinogram from the restored low-resolution image; restoring a sinogram by disposing the calculated sinogram data in the original sinogram and by utilizing the calculated sinogram data as pre-information; and restoring a final CT image from the restored sinogram. Through introduction of a novel metal artifact reduction (MAR) technique referred to as an algebraic correction technique (ACT) using an intermediate image of an attenuation coefficient of an outside of a metal area, an image closest to an original image can be obtained by minimizing metal artifacts in CT.
    • 公开了一种在计算机断层摄影(CT)中减少金属伪影的方法。 降低CT中金属伪影的方法包括:从原始正弦图获得尺寸减小的正弦图; 根据剩余的数据建立线性代数方程,不包括基于获得的正弦图的金属损坏的数据; 基于建立的线性代数方程恢复低分辨率图像; 从恢复的低分辨率图像中计算正弦图; 通过将计算的正弦图数据放置在原始正弦图中并通过利用计算的正弦图数据作为预信息来恢复正弦图; 并从恢复的正弦图恢复最终CT图像。 通过引入使用金属区域的外部的衰减系数的中间图像被称为代数校正技术(ACT)的新颖的金属伪影减少(MAR)技术,可以通过最小化最小化原始图像的图像来获得最接近原始图像的图像 CT中的金属文物。
    • 6. 发明授权
    • Method of isolating and culturing mesenchymal stem cell derived from umbilical cord blood
    • 分离和培养衍生自脐带血的间充质干细胞的方法
    • US07704739B2
    • 2010-04-27
    • US10579070
    • 2004-10-25
    • Hoon HanSung-Whan Kim
    • Hoon HanSung-Whan Kim
    • C12N5/00C12N5/08
    • C12N5/0665C12N2501/125C12N2501/22C12N2501/2303C12N2501/2306
    • The present invention relates to a method of isolating and culturing mesenchymal stem cells using umbilical cord blood that is most ideal for cell therapy. The method comprises adding an anti-coagulant to umbilical cord blood having a volume of more than 45 ml per unit, which is obtained within 24 hours after parturition; diluting the resulting mixture of the anti-coagulant and umbilical cord blood with an αMEM (alpha-minimum essential medium), followed by centrifugation to harvest monocytes; and subjecting the obtained monocytes into suspension culture in the αMEM containing Stem Cell Factor, GM-CSF (granulocyte-macrophage colony-stimulating factor), G-CSF (granulocyte colony-stimulating factor), IL-3 (interleukin-3) and IL-6 (interleukin-6).
    • 本发明涉及一种使用脐带血分离和培养间充质干细胞的方法,其是细胞治疗最理想的方法。 该方法包括向分娩后24小时内获得的每单位体积超过45ml的脐带血添加抗凝血剂; 用αMEM(α-minimum必需培养基)稀释所得的抗凝血剂和脐带血混合物,然后离心收获单核细胞; 将所获得的单核细胞在含有干细胞因子,GM-CSF(粒细胞 - 巨噬细胞集落刺激因子),G-CSF(粒细胞集落刺激因子),IL-3(白细胞介素-3)和IL -6(白介素-6)。