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1. 发明授权

US08565851B2 Mono-phasic action potential electrogram recording catheter, and method 有权
公开(公告)号：US08565851B2
公开(公告)日：2013-10-22
申请号：US12533903
申请日：2009-07-31
申请人： Michael Lau , Randell Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haïssaguerre , Meleze Hocini
发明人： Michael Lau , Randell Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haïssaguerre , Meleze Hocini
IPC分类号： A61B5/042 , A61B18/14 , A61N1/05
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.

2. 发明申请

US20050171527A1 Circumferential ablation device assembly with an expandable member 审中-公开
标题翻译：具有可扩张构件的环形消融装置组件
公开(公告)号：US20050171527A1
公开(公告)日：2005-08-04
申请号：US11020515
申请日：2004-12-23
申请人： Sumita Bhola
发明人： Sumita Bhola
IPC分类号： A61B18/02 , A61B18/14 , A61B18/18 , A61F2/958 , A61N7/02
CPC分类号： A61B18/1492 , A61B18/02 , A61B18/18 , A61B2017/003 , A61B2018/00065 , A61B2018/00214 , A61B2018/00261 , A61B2018/00375 , A61B2018/0212 , A61N7/02
摘要： The present invention involves a surgical device and method of use, particularly an assembly and method incorporating a peanut or barbell shaped expandable member along the distal region of an ablation device to facilitate ablation of a circumferential region of tissue engaged by the expandable member. The ablation device assembly includes an elongate body with a proximal end portion, a distal end portion, and a longitudinal axis. A contact member is located along the distal end portion of the elongate body. The contact member has a circumferential wall and is expandable from a radially collapsed condition to a radially expanded condition. The contact member also includes a single chamber having first and second bulbous sections separated by a longitudinal mid-section, wherein the first bulbous section has a smaller outside diameter than the second bulbous section when the contact member is in the expanded condition. The ablation device also has an ablation element having an ablative energy source that is located along the distal end portion, wherein the ablation element cooperates with the contact member such that the ablative energy source emits a substantially circumferential pattern of energy through the circumferential wall.
摘要翻译：本发明涉及一种手术装置和使用方法，特别是沿着消融装置的远侧区域结合花生或杠铃形可扩张构件的装置和方法，以便于消融由可扩张构件接合的组织的圆周区域。消融装置组件包括具有近端部分，远端部分和纵向轴线的细长主体。接触构件沿着细长体的远端部分定位。接触构件具有圆周壁并且可从径向折叠状态扩展到径向膨胀状态。接触构件还包括具有由纵向中间部分分开的第一和第二球形部分的单个室，其中当接触构件处于膨胀状态时，第一球形部分具有比第二球形部分更小的外径。消融装置还具有消融元件，其具有沿着远端部分定位的消融能量源，其中消融元件与接触构件协作，使得烧蚀能量源通过周向壁发射基本上圆周的能量图案。

3. 发明申请

US20130006082A1 MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD 有权
标题翻译：单相电动势电位记录导管及方法
公开(公告)号：US20130006082A1
公开(公告)日：2013-01-03
申请号：US13604139
申请日：2012-09-05
申请人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART , Michel HAISSAGUERRE , Meleze HOCINI
发明人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART , Michel HAISSAGUERRE , Meleze HOCINI
IPC分类号： A61B18/14 , A61B5/042
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.
摘要翻译：用于获得单相动作电位（MAP）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。参考电极是与记录几何形状的纵向距离。可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

4. 发明授权

US08280477B2 Mono-phasic action potential electrogram recording catheter, and method 有权
标题翻译：单相动作电位记录导管及方法
公开(公告)号：US08280477B2
公开(公告)日：2012-10-02
申请号：US12511707
申请日：2009-07-29
申请人： Michael Lau , Randell Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haïssaguerre , Meleze Hocini
发明人： Michael Lau , Randell Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haïssaguerre , Meleze Hocini
IPC分类号： A61B5/042 , A61B18/14 , A61N1/05
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.
摘要翻译：用于获得单相动作电位（MAP）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。参考电极是与记录几何形状的纵向距离。可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

5. 发明授权

US08571626B2 Mono-phasic action potential electrogram recording catheter, and method 有权
标题翻译：单相动作电位记录导管及方法
公开(公告)号：US08571626B2
公开(公告)日：2013-10-29
申请号：US13604139
申请日：2012-09-05
申请人： Michael Lau , Randell L. Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haissaguerre , Meleze Hocini
发明人： Michael Lau , Randell L. Werneth , Timothy J. Corvi , Sumita Bhola , Mark T. Stewart , Michel Haissaguerre , Meleze Hocini
IPC分类号： A61B5/042 , A61B18/14 , A61N1/05
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.
摘要翻译：用于获得单相动作电位（“MAP”）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。参考电极是与记录几何形状的纵向距离。可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

6. 发明授权

US07655005B2 Circumferential ablation device assembly with dual expandable members 有权
标题翻译：具有双重可扩张构件的圆周消融装置组件
公开(公告)号：US07655005B2
公开(公告)日：2010-02-02
申请号：US11022447
申请日：2004-12-23
申请人： Sumita Bhola
发明人： Sumita Bhola
IPC分类号： A61B18/18 , A61M29/00
CPC分类号： A61N7/02 , A61B18/02 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B2017/003 , A61B2018/00065 , A61B2018/00214 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/1861
摘要： The present invention involves a surgical device and method of use, particularly an assembly and method incorporating dual expandable members along the distal region of an ablation device to facilitate ablation of a circumferential region of tissue engaged by the expandable member. The ablation device assembly includes an elongate body with a proximal end portion, a distal end portion, and a longitudinal axis. A first expansion element is located along the distal end portion of the elongate body, and is fluidly coupled to a first source of inflation fluid. A second expansion element having a circumferential wall is located along the distal end portion proximal the first expansion element, and is fluidly coupled to a second source of inflation fluid. An ablation element having an ablative energy source is located along the distal end portion within the second expansion element, wherein the ablation element cooperates with the second expansion element such that the ablative energy source emits a substantially circumferential pattern of energy through the circumferential wall.
摘要翻译：本发明涉及一种手术装置和使用方法，特别是组合和方法，其沿着消融装置的远侧区域并入双重可扩张构件，以便于消融由可扩张构件接合的组织的圆周区域。消融装置组件包括具有近端部分，远端部分和纵向轴线的细长主体。第一膨胀元件沿着细长体的远端部分定位，并且流体地联接到第一膨胀流体源。具有圆周壁的第二膨胀元件沿着靠近第一膨胀元件的远端部分定位，并且流体地联接到第二膨胀流体源。具有消融能量源的消融元件沿着第二膨胀元件内的远端部分定位，其中消融元件与第二膨胀元件配合，使得烧蚀能量源通过周向壁发射基本上圆周的能量图案。

7. 发明申请

US20050165388A1 Circumferential ablation device assembly with dual expandable members 有权
标题翻译：具有双重可扩张构件的圆周消融装置组件
公开(公告)号：US20050165388A1
公开(公告)日：2005-07-28
申请号：US11022447
申请日：2004-12-23
申请人： Sumita Bhola
发明人： Sumita Bhola
IPC分类号： A61B18/02 , A61B18/04 , A61B18/14 , A61B18/18 , A61B18/24 , A61F2/958 , A61N7/02
CPC分类号： A61N7/02 , A61B18/02 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B2017/003 , A61B2018/00065 , A61B2018/00214 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/1861
摘要： The present invention involves a surgical device and method of use, particularly an assembly and method incorporating dual expandable members along the distal region of an ablation device to facilitate ablation of a circumferential region of tissue engaged by the expandable member. The ablation device assembly includes an elongate body with a proximal end portion, a distal end portion, and a longitudinal axis. A first expansion element is located along the distal end portion of the elongate body, and is fluidly coupled to a first source of inflation fluid. A second expansion element having a circumferential wall is located along the distal end portion proximal the first expansion element, and is fluidly coupled to a second source of inflation fluid. An ablation element having an ablative energy source is located along the distal end portion within the second expansion element, wherein the ablation element cooperates with the second expansion element such that the ablative energy source emits a substantially circumferential pattern of energy through the circumferential wall.
摘要翻译：本发明涉及一种手术装置和使用方法，特别是组合和方法，其沿着消融装置的远侧区域并入双重可扩张构件，以便于消融由可扩张构件接合的组织的圆周区域。消融装置组件包括具有近端部分，远端部分和纵向轴线的细长主体。第一膨胀元件沿着细长体的远端部分定位，并且流体地联接到第一膨胀流体源。具有圆周壁的第二膨胀元件沿着靠近第一膨胀元件的远端部分定位，并且流体地联接到第二膨胀流体源。具有消融能量源的消融元件沿着第二膨胀元件内的远端部分定位，其中消融元件与第二膨胀元件配合，使得烧蚀能量源通过周向壁发射基本上圆周的能量图案。

8. 发明申请

US20110028966A1 MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD 有权
公开(公告)号：US20110028966A1
公开(公告)日：2011-02-03
申请号：US12533903
申请日：2009-07-31
申请人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
发明人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
IPC分类号： A61B18/14 , A61N1/05
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.

9. 发明申请

US20110028820A1 MONO-PHASIC ACTION POTENTIAL ELECTROGRAM RECORDING CATHETER, AND METHOD 有权
标题翻译：单相电动势电位记录导管及方法
公开(公告)号：US20110028820A1
公开(公告)日：2011-02-03
申请号：US12511707
申请日：2009-07-29
申请人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
发明人： Michael LAU , Randell WERNETH , Timothy J. CORVI , Sumita BHOLA , Mark T. STEWART
IPC分类号： A61B5/04 , A61N1/05 , A61B18/14
CPC分类号： A61B5/042 , A61B5/6858 , A61B18/1492 , A61B2018/00214 , A61B2018/00839 , A61B2018/00898 , A61N1/06
摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.
摘要翻译：用于获得单相动作电位（“MAP”）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。参考电极是与记录几何形状的纵向距离。可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

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