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1. 发明授权

US09273240B2 Method for preparing a ternary or higher zeotropic refrigerant mixture 有权
标题翻译：制备三元或更高级非共沸混合制冷剂的方法
公开(公告)号：US09273240B2
公开(公告)日：2016-03-01
申请号：US13983751
申请日：2012-02-14
申请人： Robert E. Low , Stuart Corr
发明人： Robert E. Low , Stuart Corr
IPC分类号： C09K5/04
CPC分类号： C09K5/045 , C09K2205/106 , C09K2205/126 , C09K2205/34
摘要： A method for preparing a ternary or higher zeotropic refrigerant mixture comprising components of different volatilities is described. The method comprises: mixing together the less volatile components of the mixture in a pre-blending process; and separately adding the most volatile component to the pre-blended mixture by pressure or mass flow control so that the desired initial liquid composition is attained. The liquid zeotropic refrigerant mixture that is prepared may be transferred from a container in which it is held to another container or to a piece of equipment that is to use the refrigerant mixture. This method comprises the steps of: removing at least a portion of the prepared liquid zeotropic refrigerant mixture from a container in which it is held; charging the liquid zeotropic refrigerant mixture that is removed to another container or to a piece of equipment in which it is to be used; and adding at least the most volatile component of the refrigerant mixture to the holding container to compensate for the removal of liquid refrigerant mixture therefrom.
摘要翻译：描述了一种制备包含不同挥发性组分的三元或更高级非共沸混合制冷剂混合物的方法。该方法包括：在预混合过程中将混合物中较不易挥发的组分混合在一起; 并通过压力或质量流量控制分别将最易挥发的组分加入到预混合混合物中，使得达到所需的初始液体组成。制备的液体非共沸混合制冷剂可以从其被容纳的容器中转移到另一个容器中，或者转移到使用制冷剂混合物的一件设备上。该方法包括以下步骤：将至少一部分制备的液体非共沸混合制冷剂混合物从其保持的容器中除去; 将除去的液体非共沸混合物装入另一个容器或使用其中的一件设备; 并且至少将所述制冷剂混合物中最易挥发的组分添加到所述保持容器以补偿从其中除去液体制冷剂混合物。

2. 发明申请

US20070128705A1 Enzymatic process for stereo-selective preparation of chemical compounds in hydrofluorocarbon solvents 失效
标题翻译：在氢氟烃溶剂中立体选择性制备化合物的酶法
公开(公告)号：US20070128705A1
公开(公告)日：2007-06-07
申请号：US10549357
申请日：2004-03-18
申请人： Simon Saul , Jason Micklefield , Stuart Corr
发明人： Simon Saul , Jason Micklefield , Stuart Corr
IPC分类号： C12P7/62
CPC分类号： C12P41/005 , C12P41/004
摘要： A process for preparing a second compound stereo-selectively is described. The process comprises reacting a substrate comprising at least one first compound with a reagent in the presence of a biological catalyst and a solvent comprising at least one (hydro)fluorocarbon so as to convert a first compound into the second compound.
摘要翻译：描述了用于制备立体选择性的第二化合物的方法。该方法包括在生物催化剂存在下使包含至少一种第一化合物的底物与包含至少一种（氢）氟碳化合物的溶剂反应以将第一化合物转化为第二化合物。

3. 发明授权

US07019178B2 Process for the purification of fluoromethyl hexafluoroisopropyl ether 失效
标题翻译：氟甲基六氟异丙醚的纯化方法
公开(公告)号：US07019178B2
公开(公告)日：2006-03-28
申请号：US10451265
申请日：2001-12-21
申请人： Andrew P. Sharratt , Stuart Corr
发明人： Andrew P. Sharratt , Stuart Corr
IPC分类号： C07C41/34
CPC分类号： C07C41/36 , C07C43/123
摘要： A process for the purification of fluoromethyl hexafluoroisopropyl ether involving contacting a crude composition containing impure fluoromethyl hexafluoroisopropyl ether with an adsorbent having pores with a range of pore sizes whereby the difference between the smallest and largest pore size is at least 1 nm. The adsorbent suitably is a form of silica, alumina, or carbon.
摘要翻译：涉及氟代甲基六氟异丙醚的纯化方法，包括使含有不纯的氟甲基六氟异丙醚的粗制组合物与具有孔径范围的孔的吸附剂接触，由此最小孔径和最大孔径之差至少为1nm。吸附剂合适地是二氧化硅，氧化铝或碳的形式。

4. 发明授权

US07001511B2 Apparatus and method for removing solvent residues 失效
标题翻译：用于除去溶剂残留物的装置和方法
公开(公告)号：US07001511B2
公开(公告)日：2006-02-21
申请号：US10623308
申请日：2003-07-18
申请人： Stuart Corr , Paul A. Dowdle , Robert E. Low , James David Morrison , Frederick Thomas Murphy
发明人： Stuart Corr , Paul A. Dowdle , Robert E. Low , James David Morrison , Frederick Thomas Murphy
IPC分类号： C02F1/00
CPC分类号： B01D5/0039 , B01D3/007 , B01D3/40 , B01D11/0219 , B01D11/028
摘要： In the field of biomass extraction, there is a need for effective removal of solvent from spent biomass material. An apparatus for removing solvent residues includes a vessel (11) for containing biomass; a steam source (19) for supplying steam to contact the biomass; and a separator (24) for separating solvent from steam that has contacted the biomass. The disclosure also includes a method of use of the apparatus.
摘要翻译：在生物质提取领域，需要从废弃生物质材料中有效去除溶剂。用于除去溶剂残留物的装置包括用于容纳生物质的容器（11）蒸汽源（19），用于供应蒸汽以接触生物质; 以及用于从已经接触生物质的蒸汽中分离溶剂的分离器（24）。本公开还包括使用该装置的方法。

5. 发明申请

US20050261526A1 Process for the purification of fluoromethyl hexafluoroisopropyl ether 失效
标题翻译：氟甲基六氟异丙醚的纯化方法
公开(公告)号：US20050261526A1
公开(公告)日：2005-11-24
申请号：US10451265
申请日：2001-12-21
申请人： Andrew Sharratt , Stuart Corr
发明人： Andrew Sharratt , Stuart Corr
IPC分类号： C07C41/36 , C07C43/04 , C07C43/12
CPC分类号： C07C41/36 , C07C43/123
摘要： A process for the purification of fluoromethyl hexafluoroisopropyl ether involving contacting a crude composition containing impure fluoromethyl hexafluoroisopropyl ether with an adsorbent having pores with a range of pore sizes whereby the difference between the smallest and largest pore size is at least 1 nm. The adsorbent suitably is a form of silica, alumina, or carbon.
摘要翻译：涉及氟代甲基六氟异丙醚的纯化方法，包括使含有不纯的氟甲基六氟异丙醚的粗制组合物与具有孔径范围的孔的吸附剂接触，由此最小孔径和最大孔径之差至少为1nm。吸附剂合适地是二氧化硅，氧化铝或碳的形式。

6. 发明授权

US06710216B1 Method and apparatus for recovering a solvent 失效
标题翻译：用于回收溶剂的方法和设备
公开(公告)号：US06710216B1
公开(公告)日：2004-03-23
申请号：US09654746
申请日：2000-09-05
申请人： Stuart Corr , Paul A. Dowdle , Robert E. Low , James David Morrison , Frederick Thomas Murphy
发明人： Stuart Corr , Paul A. Dowdle , Robert E. Low , James David Morrison , Frederick Thomas Murphy
IPC分类号： C07C1738
CPC分类号： B01D11/0215 , A23L27/11 , B01D11/028 , B01D15/00 , B01J20/20 , C11B9/025
摘要： In a closed-loop biomass extraction apparatus (10), strategies for purifying HFC solvents used therein include: (i) contacting an adsorbent and a desiccant, e.g. in a container (26) with contaminated HFC solvent branched from the main flow loop; and, optionally, (ii) washing contaminated HFC solvent with water, e.g. in a vessel (34) to separate a co-solvent or entrainer, such as ethanol, thereform.
摘要翻译：在闭环生物质提取装置（10）中，用于纯化HFC溶剂的策略包括：（i）使吸附剂和干燥剂，例如，在具有从主流回路分支的污染的HFC溶剂的容器（26）中; 和（ii）用水洗涤被污染的HFC溶剂。在容器（34）中分离共溶剂或夹带剂，例如乙醇。

7. 发明授权

US06495060B2 Refrigerant compositions 失效
标题翻译：制冷剂组合物
公开(公告)号：US06495060B2
公开(公告)日：2002-12-17
申请号：US09242809
申请日：2000-02-10
申请人： Richard L. Powell , Stuart Corr , Frederick T. Murphy , James D. Morrison
发明人： Richard L. Powell , Stuart Corr , Frederick T. Murphy , James D. Morrison
IPC分类号： C09K500
CPC分类号： C09K5/045 , C09K2205/22 , C09K2205/41
摘要： A composition comprising (A) 1,1,2,2,3-pentafluoropropane(CF2HCF2CFH2) and (B) at least one hydrofluorocarbon selected from the group consisting of 1,1,1,3,3-pentafluoropropane (CF3CH2CF2H) and 1,1,1,2,2,3,3,4,4-nonafluorobutane (CF3CF2CF2CF2H) is described. The composition is useful as a refrigerant and may be used in chillers as a replacement for refrigerant R-11.
摘要翻译：一种组合物，其包含（A）1,1,2,2,3-五氟丙烷（CF 2 HCF 2 CFH 2）和（B）至少一种选自1,1,1,3,3-五氟丙烷（CF 3 CH 2 CF 2 H）和1 ，1,1,2,2,3,3,4,4-九氟丁烷（CF 3 CF 2 CF 2 CF 2 H）。该组合物可用作制冷剂，并且可用于冷却器中作为制冷剂R-11的替代物。

8. 发明申请

US20160263150A1 TUNING BIOLOGICAL SYSTEM PROPERTIES FOR OPTIMIZED TREATMENT EFFICACY 审中-公开
标题翻译：调节生物系统性能优化治疗效果
公开(公告)号：US20160263150A1
公开(公告)日：2016-09-15
申请号：US15067010
申请日：2016-03-10
申请人： Nadia C. Lara , Andrew R. Barron , Stuart Corr , Steven Curley
发明人： Nadia C. Lara , Andrew R. Barron , Stuart Corr , Steven Curley
IPC分类号： A61K33/00
CPC分类号： A61K33/44 , A61K9/14 , A61K33/10 , A61K33/24
摘要： Various embodiments of the present disclosure pertain to methods of optimizing a treatment efficacy of a biological system by tuning a property of the biological system through the addition of an optimizing agent to the biological system. The tuning can include: (a) determining a property parameter of the biological system; (b) selecting an optimizing agent to be added to the biological system based on the determined property parameter; and (c) adding the optimizing agent to the biological system. The optimizing agent can include a kosmotropic material. The biological system can include a tissue, such as a tumor. The methods of the present disclosure can be utilized to enhance the efficacy of various treatments, such as the heat treatment of a biological system exposed to a radiofrequency field. The methods of the present disclosure can also include a step of treating the biological system.
摘要翻译：本公开的各种实施方案涉及通过通过向生物系统添加优化剂来调节生物系统的性质来优化生物系统的治疗功效的方法。调整可以包括：（a）确定生物系统的属性参数; （b）基于所确定的属性参数选择要添加到所述生物系统的优化剂; 和（c）将优化剂加入到生物系统中。优化剂可以包括一种感光性材料。生物系统可以包括诸如肿瘤的组织。本公开的方法可以用于增强各种治疗的功效，例如暴露于射频场的生物系统的热处理。本公开的方法还可以包括处理生物系统的步骤。

9. 发明申请

US20140234229A1 PHARMACEUTICAL COMPOSITIONS 审中-公开
标题翻译：药物组合物
公开(公告)号：US20140234229A1
公开(公告)日：2014-08-21
申请号：US14117340
申请日：2012-05-11
申请人： Stuart Corr , Timothy James Noakes
发明人： Stuart Corr , Timothy James Noakes
IPC分类号： A61K31/573 , A61K31/56 , A61K9/00
CPC分类号： A61K9/124 , A61K9/008 , A61K31/56 , A61K31/573 , A61K47/06 , A61K47/10
摘要： A pharmaceutical solution for a medication delivery apparatus, especially a metered dose inhaler, is described. The pharmaceutical solution comprises: (a) a liquefied propellant component consisting essentially of and preferably consisting entirely of 1,1-difluoroethane (R-152a); (b) ethanol; and (c) a drug component dissolved in the propellant/ethanol mixture consisting of at least one drug selected from the group consisting of beclomethasone dipropionate (BDP) and fluticasone propionate (FP).
摘要翻译：描述了用于药物输送装置，特别是计量剂量吸入器的药物溶液。药物溶液包括：（a）基本上由和优选全部由1,1-二氟乙烷（R-152a）组成的液化推进剂组分; （b）乙醇; 和（c）溶解在由至少一种选自二丙酸倍氯米松（BDP）和丙酸氟替卡松（FP））组成的组中的推进剂/乙醇混合物中的药物成分。

10. 发明申请

US20090158771A1 Heat Transfer compositions 失效
标题翻译：热转印组合物
公开(公告)号：US20090158771A1
公开(公告)日：2009-06-25
申请号：US12287880
申请日：2008-10-14
申请人： Robert E. Low , Stuart Corr
发明人： Robert E. Low , Stuart Corr
IPC分类号： F25B1/00 , C09K5/04 , C08J9/14 , F01K25/00
CPC分类号： C09K5/045 , C08J9/146 , C08J2207/04 , C09K2205/126 , C09K2205/22 , C11D7/5018 , Y02P20/124
摘要： Heat transfer compositions are usable in their own right or are suitable as a replacement for existing refrigeration usages. The compositions possess a reduced Greenhouse Warming Potential, yet have a capacity and energy efficiency (which may be conveniently expressed as the “Coefficient of Performance”) ideally within 20% of the values of those attained using R-134a, and preferably within 10% or less (e.g. about 5%) of these values.
摘要翻译：热转印组合物本身可以使用或适合作为现有制冷用途的替代物。该组合物具有降低的温室暖化潜力，但具有能力和能量效率（其可以方便地表示为“性能系数”），理想地在使用R-134a达到的值的20％内，优选在10％或更低（例如约5％）。

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