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1. 发明申请

US20130141246A1 Display Of A System State Of A Treatment Device For Microscopic Samples 有权
标题翻译：显微镜样品处理装置的系统状态
公开(公告)号：US20130141246A1
公开(公告)日：2013-06-06
申请号：US13509421
申请日：2010-11-15
申请人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
发明人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
IPC分类号： G08B5/36
CPC分类号： G08B5/36 , G01N1/36 , G01N2035/00891
摘要： The invention relates to a method of displaying a system state of an automatic treatment device, a corresponding display system which is configured for carrying out the method, and a treatment device equipped with the display system. At least one system parameter (121, 122, 123) is determined, the at least one determined (120) system parameter (121, 122, 123) is evaluated on the basis of evaluation criteria, the system state is evaluated on the basis of the at least one evaluated (130) system parameter (121, 122, 123), and the evaluated (140) system state is displayed by a traffic light function (175).
摘要翻译：本发明涉及一种显示自动处理装置的系统状态的方法，配置为执行该方法的相应显示系统以及配备有显示系统的处理装置。确定至少一个系统参数（121,122,123），基于评估标准来评估至少一个确定的（120）系统参数（121,122,123），系统状态基于通过交通灯功能（175）显示所述至少一个评估系统参数（121,122,123）和所述评估（140）系统状态。

2. 发明授权

US08431091B2 Tissue embedding apparatus, and method for operating a tissue embedding apparatus 有权
标题翻译：组织嵌入装置和组织嵌入装置的操作方法
公开(公告)号：US08431091B2
公开(公告)日：2013-04-30
申请号：US12599050
申请日：2008-04-23
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel
IPC分类号： A61B10/00
CPC分类号： G01N1/31 , G01N1/36
摘要： The invention relates to a tissue embedding apparatus (1) for automatic embedding at least one tissue sample (8). Said tissue embedding device (1) comprises an input unit (2), an image recording unit (3), an embedding unit (4), at least one output unit (5, 6), and a control unit (7). A cassette (9) containing at least one tissue sample (8) can be transferred to the input unit (2) of the tissue embedding device (1). The embedding unit (4) allows the tissue sample (8) to be embedded in an embedding medium, while the at least one output unit (5) allows the embedded tissue sample to be output. The image recording unit (3) makes it possible to record at least one image of the tissue sample (8). In order to be able to embed tissue in an automated manner also when different cassettes are used, a tissue embedding device (1) according to the invention is characterized in that the recorded image of the tissue sample (8) can be evaluated while further processing of the tissue sample (8) in the tissue embedding device (1) can be predefined in accordance with the evaluation of the image.
摘要翻译：本发明涉及一种用于自动包埋至少一个组织样品（8）的组织包埋装置（1）。所述组织嵌入装置（1）包括输入单元（2），图像记录单元（3），嵌入单元（4），至少一个输出单元（5,6）和控制单元（7）。包含至少一个组织样本（8）的盒（9）可以被传送到组织嵌入装置（1）的输入单元（2）。嵌入单元（4）允许组织样本（8）嵌入到嵌入介质中，而至少一个输出单元（5）允许输出嵌入的组织样本。图像记录单元（3）使得可以记录组织样本（8）的至少一个图像。为了能够在使用不同的盒子时能够以自动方式嵌入组织，根据本发明的组织包埋装置（1）的特征在于可以进一步处理组织样本（8）的记录图像，可以根据图像的评估来预先确定组织包埋装置（1）中的组织样本（8）。

3. 发明授权

US08312796B2 Microtome 有权
标题翻译：切片机
公开(公告)号：US08312796B2
公开(公告)日：2012-11-20
申请号：US11693014
申请日：2007-03-29
申请人： Stefan Künkel , Frank Sauer , Volker Schneider
发明人： Stefan Künkel , Frank Sauer , Volker Schneider
IPC分类号： B26D7/06 , B23D19/00 , B27B5/18
CPC分类号： G01N1/06 , Y10T83/202 , Y10T83/6492 , Y10T83/6508
摘要： The present invention relates to a microtome (1) having functional regions to be operated manually, in particular a sample holder (2), a cutting device (3), a section removal system (4), and a section collection pan (5). A microtome (1) is described in which the particularly firm contact or adhesion of sectioning waste fragments and, in particular, of thin sections can be at least largely avoided. For this purpose, the microtome (1) according to the present invention is characterized in that the components of the microtome (1) that can be brought into contact with paraffin sections are embodied in electrically conductive fashion.
摘要翻译：本发明涉及具有手动操作的功能区域的切片机（1），特别是样品架（2），切割装置（3），部分移除系统（4）和部分收集盘（5）。描述了一种切片机（1），其中可以至少在很大程度上避免切片废料碎片，特别是薄部分的特别牢固的接触或粘附。为此，根据本发明的切片机（1）的特征在于，与石蜡切片接触的切片机（1）的部件以导电方式实现。

4. 发明申请

US20100099199A1 METHOD AND APPARATUS FOR ASCERTAINING REAGENT QUALITY 审中-公开
标题翻译：用于测定试剂质量的方法和装置
公开(公告)号：US20100099199A1
公开(公告)日：2010-04-22
申请号：US12580203
申请日：2009-10-15
申请人： Markus Egle , Robert Gropp , Stefan Künkel , Karl-Heinz Westerhoff
发明人： Markus Egle , Robert Gropp , Stefan Künkel , Karl-Heinz Westerhoff
IPC分类号： G01N1/00 , C12M1/34
CPC分类号： G01N35/00663 , G01N1/312 , G01N2035/00673 , Y10T436/25
摘要： A method for determining reagent quality in a device having multiple treatment stations for the treatment of at least one of cytological and histological prepared specimens and an apparatus for performing this method are described. The method comprises providing a carrier element that comprises at least one test material; transferring and treating the carrier element having test material according to a predefined sequence in a plurality of the treatment stations together with the specimens; and evaluating the test material by means of an evaluation device after treatment in the last treatment station in sequence. The described method and apparatus achieve that reagent quality can be determined automatically and the reagents can be replaced at an optimum point in time.
摘要翻译：描述了一种用于确定具有用于治疗细胞学和组织学制备的样本中的至少一个的多个治疗站的装置中的试剂质量的方法和用于执行该方法的装置。该方法包括提供包括至少一种测试材料的载体元件; 在多个处理站中按照预定的顺序，将样品转移和处理具有测试材料的载体元件; 并且在最后一个处理站中依次用处理后的评价装置对试验材料进行评价。所描述的方法和装置实现了可以自动确定试剂质量，并且可以在最佳时间点更换试剂。

5. 发明授权

US08039262B2 Method for controlling a tissue processor and tissue processor 有权
标题翻译：用于控制组织处理器和组织处理器的方法
公开(公告)号：US08039262B2
公开(公告)日：2011-10-18
申请号：US12545586
申请日：2009-08-21
申请人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
发明人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
IPC分类号： C12Q3/00 , C12M1/36 , C12M3/00 , G01N33/48
CPC分类号： G01N35/00623 , Y10T436/11 , Y10T436/115831 , Y10T436/12
摘要： A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided including a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented.
摘要翻译：描述了一种用于控制组织处理器和用于处理组织样本的组织处理器的方法。提供了一种蒸煮器，其包括可由操作者打开和关闭的盖子。在组织处理之前关闭蒸煮盖。可以确定第一和第二操作元件的致动状态。提示操作者通过致动第二操作元件来确认关闭的蒸煮盖的解锁。当确定第二操作元件的致动并且关闭的蒸煮盖被解锁并在蒸煮盖再次被锁定之后继续时，纸巾处理被中断。在完成纸巾处理后，解冻盖子。通过所描述的方法和组织处理器，防止在持续的组织处理期间不适当的干预。

6. 发明授权

US07722811B2 Tissue processor 有权
标题翻译：组织处理器
公开(公告)号：US07722811B2
公开(公告)日：2010-05-25
申请号：US11562710
申请日：2006-11-22
申请人： Marc Konrad , Stefan Künkel , Holger Metzner , Eberhard Sendobry , Markus Dobusch
发明人： Marc Konrad , Stefan Künkel , Holger Metzner , Eberhard Sendobry , Markus Dobusch
IPC分类号： G01N21/00
CPC分类号： G01N1/31 , B01L3/16 , G01N35/1067 , G01N35/1072 , Y10T436/113332
摘要： A tissue processor (1) is described, having a retort (2) for processing histological samples with different reagents, having multiple reagent reservoir vessels (3), and having a conduit system and a control device (5) for delivering reagents out of the reagent reservoir vessels (3) into the retort (2). A suction conduit (11) projects into each reagent reservoir vessel (3) through the vessel opening (7) for reagent withdrawal. A closure system (12) having an externally tapered and internally hollow closure plug (13) is provided for closing off the vessel opening (7). The suction conduit (11) is guided through a cavity (14) of the closure plug (13) for reagent withdrawal.
摘要翻译：描述了一种组织处理器（1），其具有用于用不同试剂处理组织学样品的蒸馏器（2），具有多个试剂储存容器（3），并具有导管系统和控制装置（5），用于将试剂输出试剂库容器（3）进入蒸馏器（2）。抽吸管道（11）通过容器开口（7）突出到每个试剂储存容器（3）中以用于试剂取出。提供具有外锥形和内部中空的封闭塞（13）的封闭系统（12），用于封闭容器开口（7）。吸入管道（11）被引导通过封闭塞（13）的空腔（14）以用于试剂取出。

7. 发明授权

US07673546B2 Microtome having a cooling device 失效
标题翻译：切片机具有冷却装置
公开(公告)号：US07673546B2
公开(公告)日：2010-03-09
申请号：US11610555
申请日：2006-12-14
申请人： Claudia Dorenkamp , Stefan Künkel
发明人： Claudia Dorenkamp , Stefan Künkel
IPC分类号： G01N1/06
CPC分类号： G01N1/42 , G01N1/06 , Y10T83/202 , Y10T83/283
摘要： A microtome (1), having a knife (9) for sectioning a specimen (5) for subsequent microscopic examination, is described. The microtome (1) comprises a cooled specimen holder (2) for receiving the specimen (5), the specimen holder (2) being connected to a coolant circuit (3). Additionally associated with the specimen holder (2) is a cooled thermal conduction plate (4) that can be placed over the specimen (5).
摘要翻译：描述了具有用于将样品（5）切片用于随后显微镜检查的刀（9）的切片机（1）。切片机（1）包括用于接收样本（5）的冷却的样本保持器（2），样本保持器（2）连接到冷却剂回路（3）。另外与样品架（2）相关联的是可放置在样品（5）上方的冷却导热板（4）。

8. 发明申请

US20100055663A1 METHOD FOR CONTROLLING A TISSUE PROCESSOR AND TISSUE PROCESSOR 有权
标题翻译：用于控制组织处理器和组织处理器的方法
公开(公告)号：US20100055663A1
公开(公告)日：2010-03-04
申请号：US12545586
申请日：2009-08-21
申请人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
发明人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
IPC分类号： C12M1/00 , C12Q3/00
CPC分类号： G01N35/00623 , Y10T436/11 , Y10T436/115831 , Y10T436/12
摘要： A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided comprising a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented.
摘要翻译：描述了一种用于控制组织处理器和用于处理组织样本的组织处理器的方法。提供了一种蒸煮器，其包括可由操作者打开和关闭的盖子。在组织处理之前关闭蒸煮盖。可以确定第一和第二操作元件的致动状态。提示操作者通过致动第二操作元件来确认关闭的蒸煮盖的解锁。当确定第二操作元件的致动并且关闭的蒸煮盖被解锁并在蒸煮盖再次被锁定之后继续时，纸巾处理被中断。在完成纸巾处理后，解冻盖子。通过所描述的方法和组织处理器，防止在持续的组织处理期间不适当的干预。

9. 发明申请

US20120052526A1 Tissue Infiltration Method 有权
标题翻译：组织浸润法
公开(公告)号：US20120052526A1
公开(公告)日：2012-03-01
申请号：US13271953
申请日：2011-10-12
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet I. Minshew
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet I. Minshew
IPC分类号： C12Q1/02
CPC分类号： G01N1/31 , Y10T436/2575
摘要： A tissue infiltration apparatus (1) for specimens present in cassettes (5) comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to, and/or movable away from, a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) is definable. To enable accelerated or preferred processing of a transport basket (4) with the tissue infiltration apparatus (1), at least one means (8) is provided with which the order of two transport baskets (4) is definably modifiable.
摘要翻译：用于盒（5）中的样本的组织浸渗装置（1）包括至少两个液体容器（7,11,13,15）和输送装置（6）。多个盒（5）可接收在运输篮（4）中。输送装置（6）构造成使得至少两个输送筐（4）能够在组织浸渗装置（1）中运输。运输篮（4）可与运输设备（6）一起运送到和/或移动离开液体容器（7,11,13,15）。运输篮（4）通过液体容器（7,11,13,15）的执行顺序（21）是可定义的。为了能够利用组织渗透装置（1）加速或优选地加工运输篮（4），提供至少一个装置（8），两个运输篮（4）的顺序是可定义地可修改的。

10. 发明授权

US08890709B2 Display of a system state of a treatment device for microscopic samples 有权
标题翻译：显示微观样品处理装置的系统状态
公开(公告)号：US08890709B2
公开(公告)日：2014-11-18
申请号：US13509421
申请日：2010-11-15
申请人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
发明人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
IPC分类号： G08B5/36 , G01N1/36 , G01N35/00
CPC分类号： G08B5/36 , G01N1/36 , G01N2035/00891
摘要： The invention relates to a method of displaying a system state of an automatic treatment device, a corresponding display system which is configured for carrying out the method, and a treatment device equipped with the display system. At least one system parameter (121, 122, 123) is determined, the at least one determined (120) system parameter (121, 122, 123) is evaluated on the basis of evaluation criteria, the system state is evaluated on the basis of the at least one evaluated (130) system parameter (121, 122, 123), and the evaluated (140) system state is displayed by a traffic light function (175).
摘要翻译：本发明涉及一种显示自动处理装置的系统状态的方法，配置为执行该方法的相应显示系统以及配备有显示系统的处理装置。确定至少一个系统参数（121,122,123），基于评估标准来评估至少一个确定的（120）系统参数（121,122,123），系统状态基于通过交通灯功能（175）显示所述至少一个评估系统参数（121,122,123）和所述评估（140）系统状态。

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