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1. 发明专利

CA139676S LADDER LOCKING DEVICE 未知
公开(公告)号：CA139676S
公开(公告)日：2011-10-24
申请号：CA139676
申请日：2011-03-21
申请人： SEAN EVANS , LOKALADDA PTY LTD
摘要： The design is the visual features of shape and configuration of the LADDER LOCKING DEVICE as shown in the drawings.

2. 发明授权

US5968526A T cell epitopes of the major allergens from Dermatophagoides (house dust mite) 失效
标题翻译：来自Dermatophagoides的主要过敏原的T细胞表位（房尘螨）
公开(公告)号：US5968526A
公开(公告)日：1999-10-19
申请号：US478572
申请日：1995-06-07
申请人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze'ev Shaked
发明人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze'ev Shaked
IPC分类号： A61K38/00 , A61K39/00 , A61P37/08 , C07K14/435 , A61K39/35 , A61K39/395 , G01N33/53 , G01N33/573
CPC分类号： C07K14/43531 , A61K38/00 , A61K39/00 , C07K2319/40
摘要： The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allergen selected from the allergens Der p I, Der p II, Der f I, or Der f II. The invention also pertains to modified peptides having similar or enhanced therapeutic properties as the corresponding, naturally-occurring allergen or portion thereof, but having reduced side effects. The invention further provides nucleic acid sequences coding for peptides of the invention. Methods of treatment or of diagnosis of sensitivity to house dust mites in an individual and therapeutic compositions comprising one or more peptides of the invention are also provided.
摘要翻译：本发明提供了Dermatophagoides属主要蛋白质过敏原的分离的肽。本发明范围内的肽包含至少一种T细胞表位，或优选至少两种选自变应原Der p I，Der p II，Der f I或Der f II的蛋白质变应原的T细胞表位。本发明还涉及与相应的天然存在的变应原或其部分具有相似或增强的治疗性质但具有减少的副作用的修饰肽。本发明还提供了编码本发明的肽的核酸序列。还提供了治疗或诊断对个体中的尘螨的敏感性的方法和包含本发明的一种或多种肽的治疗组合物。

3. 发明授权

US5820862A T cell epitopes of the major allergens from dermatophagoides (house dust mite) 失效
标题翻译：来自皮肤癣菌的主要过敏原的T细胞表位（房尘螨）
公开(公告)号：US5820862A
公开(公告)日：1998-10-13
申请号：US482142
申请日：1995-06-07
申请人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze'ev Shaked
发明人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze'ev Shaked
IPC分类号： A61K38/00 , A61K39/00 , A61P37/08 , C07K14/435 , A61K39/35
CPC分类号： C07K14/43531 , A61K38/00 , A61K39/00 , C07K2319/40
摘要： The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allergen selected from the allergens Der p I, Der p II, Der f I, or Der f II. The invention also pertains to modified peptides having similar or enhanced therapeutic properties as the corresponding, naturally-occurring allergen or portion thereof, but having reduced side effects. The invention further provides nucleic acid sequences coding for peptides of the invention. Methods of treatment or of diagnosis of sensitivity to house dust mites in an individual and therapeutic compositions comprising one or more peptides of the invention are also provided.
摘要翻译：本发明提供了Dermatophagoides属主要蛋白质过敏原的分离的肽。本发明范围内的肽包含至少一种T细胞表位，或优选至少两种选自变应原Der p I，Der p II，Der f I或Der f II的蛋白质变应原的T细胞表位。本发明还涉及与相应的天然存在的变应原或其部分具有相似或增强的治疗性质但具有减少的副作用的修饰肽。本发明还提供了编码本发明的肽的核酸序列。还提供了治疗或诊断对个体中的尘螨的敏感性的方法和包含本发明的一种或多种肽的治疗组合物。

4. 发明申请

US20120027512A1 LOCK 审中-公开
标题翻译：锁
公开(公告)号：US20120027512A1
公开(公告)日：2012-02-02
申请号：US13191753
申请日：2011-07-27
申请人： Sean Evans
发明人： Sean Evans
IPC分类号： F16B1/00
CPC分类号： B60R9/0485 , Y10T403/74
摘要： A lock for retaining one or more ladders or trestles to a rack comprises a hook which hooks under the rack while the shaft of the hook extends through and beyond the one or more ladders or trestles and a cross beam with a flange at each end which receives the shaft of the hook and sits on and around the one or more ladders or trestles and a handle which also receives the shaft of the hook and secures the cross beam in place thereby fastening the one or more ladders or trestles to the rack and wherein said cross beam is extendable to fit a variety of ladder or trestle sizes.
摘要翻译：用于将一个或多个梯子或支架保持在架子上的锁定件包括一钩钩钩在齿条下方，而钩的轴延伸穿过并超过一个或多个梯子或支架，以及横梁，每个端部均带有法兰钩的轴并且坐在一个或多个梯子或支架上和周围，并且还具有接收钩的轴并且将横梁固定在适当位置的手柄，从而将一个或多个梯子或支架固定到支架上，并且其中所述横梁可以延伸以适应各种梯子或支架尺寸。

5. 发明授权

US06268491B1 T cell epitopes of the major allergens from dermatophagoides (house dust mite) 失效
标题翻译：来自皮肤癣菌的主要过敏原的T细胞表位（房尘螨）
公开(公告)号：US06268491B1
公开(公告)日：2001-07-31
申请号：US08484296
申请日：1995-06-07
申请人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze′ev Shaked
发明人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze′ev Shaked
IPC分类号： C07H2104
CPC分类号： C07K14/415 , A61K38/00 , A61K39/00 , C07K14/43531 , C07K14/4705 , C07K2319/00 , C07K2319/40 , C12N15/62 , G01N33/5091
摘要： The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allergen selected from the allergens Der p I, Der p II, Der f I, or Der f II. The invention also pertains to modified peptides having similar or enhanced therapeutic properties as the corresponding, naturally-occurring allergen or portion thereof, but having reduced side effects. The invention further provides nucleic acid sequences coding for peptides of the invention. Methods of treatment or of diagnosis of sensitivity to house dust mites in an individual and therapeutic compositions comprising one or more peptides of the invention are also provided.
摘要翻译：本发明提供了Dermatophagoides属主要蛋白质过敏原的分离的肽。本发明范围内的肽包含至少一种T细胞表位，或优选至少两种选自变应原Der p I，Der p II，Der f I或Der f II的蛋白质变应原的T细胞表位。本发明还涉及与相应的天然存在的变应原或其部分具有相似或增强的治疗性质但具有减少的副作用的修饰肽。本发明还提供了编码本发明的肽的核酸序列。还提供了治疗或诊断对个体中的尘螨的敏感性的方法和包含本发明的一种或多种肽的治疗组合物。

6. 外观设计

USD667564S1 Locking device 有权
标题翻译：锁定设备
公开(公告)号：USD667564S1
公开(公告)日：2012-09-18
申请号：US29382521
申请日：2011-01-04
申请人： Sean Evans
设计人： Sean Evans

7. 发明授权

US07288256B1 T cell epitopes of the major allergens from dermatophagoides (house dust mite) 失效
标题翻译：来自皮肤癣菌的主要过敏原的T细胞表位（房尘螨）
公开(公告)号：US07288256B1
公开(公告)日：2007-10-30
申请号：US08445307
申请日：1995-05-19
申请人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze'ev Shaked
发明人： Richard D. Garman , Julia L. Greenstein , Mei-chang Kuo , Bruce L. Rogers , Henry M. Franzen , Xian Chen , Sean Evans , Ze'ev Shaked
IPC分类号： A61K38/43
CPC分类号： C07K14/415 , A61K38/00 , A61K39/00 , C07K14/43531 , C07K14/4705 , C07K2319/00 , C07K2319/40 , C12N15/62 , G01N33/5091
摘要： The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allergen selected from the allergens Der p I, Der p II, Der f I, or Der f II. The invention also pertains to modified peptides having similar or enhanced therapeutic properties as the corresponding, naturally-occurring allergen or portion thereof, but having reduced side effects. The invention further provides nucleic acid sequences coding for peptides of the invention. Methods of treatment or of diagnosis of sensitivity to house dust mites in an individual and therapeutic compositions comprising one or more peptides of the invention are also provided.
摘要翻译：本发明提供了Dermatophagoides属主要蛋白质过敏原的分离的肽。本发明范围内的肽包含至少一种T细胞表位，或优选至少两种选自变应原Der p I，Der p II，Der f I或Der f II的蛋白质变应原的T细胞表位。本发明还涉及与相应的天然存在的变应原或其部分具有相似或增强的治疗性质但具有减少的副作用的修饰肽。本发明还提供了编码本发明的肽的核酸序列。还提供了治疗或诊断对个体中的尘螨的敏感性的方法和包含本发明的一种或多种肽的治疗组合物。

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