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1. 发明授权

US08602998B2 Use of relaxin to increase arterial compliance 有权
标题翻译：使用松弛素增加动脉顺应性
公开(公告)号：US08602998B2
公开(公告)日：2013-12-10
申请号：US12985714
申请日：2011-01-06
申请人： Kirk P Conrad , Sanjeev G Shroff
发明人： Kirk P Conrad , Sanjeev G Shroff
IPC分类号： A61B5/00 , A61B5/02
CPC分类号： A61K38/2221 , A61B5/02007
摘要： The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
摘要翻译：本发明提供了增加动脉顺应性的方法。所述方法通常涉及向有需要的个体施用有效量的松弛素。本发明还提供了具有1型或2型糖尿病的个体中增加动脉顺应性的方法。本发明还提供了在绝经期，绝经期和绝经后妇女中增加动脉顺应性的方法。本发明进一步提供了增加具有或有风险发展年龄相关动脉僵硬的个体中的动脉顺应性的方法。

2. 发明申请

US20110137291A1 USE OF RELAXIN TO INCREASE ARTERIAL COMPLIANCE 有权
标题翻译：使用放射疗法提高术前符合度
公开(公告)号：US20110137291A1
公开(公告)日：2011-06-09
申请号：US12985714
申请日：2011-01-06
申请人： Kirk P. CONRAD , Sanjeev G. Shroff
发明人： Kirk P. CONRAD , Sanjeev G. Shroff
IPC分类号： A61M31/00
CPC分类号： A61K38/2221 , A61B5/02007
摘要： The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
摘要翻译：本发明提供了增加动脉顺应性的方法。所述方法通常涉及向有需要的个体施用有效量的松弛素。本发明还提供了具有1型或2型糖尿病的个体中增加动脉顺应性的方法。本发明还提供了在绝经期，绝经期和绝经后妇女中增加动脉顺应性的方法。本发明进一步提供了增加具有或有风险发展年龄相关动脉僵硬的个体中的动脉顺应性的方法。

3. 发明申请

US20150232526A1 USE OF RELAXIN TO TREAT ATRIAL FIBRILLATION 审中-公开
标题翻译：使用松弛素治疗椎间盘突出症
公开(公告)号：US20150232526A1
公开(公告)日：2015-08-20
申请号：US14434681
申请日：2013-10-10
申请人： David S. SCHWARTZMAN , Sanjeev G. SHROFF , Guy SALAMA , Charles F. MCTIERNAN
发明人： David S. Schwartzman , Sanjeev G. Shroff , Guy Salama , Charles F. McTiernan
IPC分类号： C07K14/575
CPC分类号： C07K14/575 , A61K38/2221 , A61K45/06 , A61K2300/00
摘要： Disclosed herein are methods of using relaxin polypeptides and analogs, or nucleic acid molecules encoding such polypeptides to treat or inhibit atrial fibrillation.
摘要翻译：本文公开了使用松弛素多肽和类似物或编码这些多肽的核酸分子来治疗或抑制心房颤动的方法。

4. 发明申请

US20140057832A1 USE OF RELAXIN TO INCREASE ARTERIAL COMPLIANCE 审中-公开
标题翻译：使用放射疗法提高术前符合度
公开(公告)号：US20140057832A1
公开(公告)日：2014-02-27
申请号：US14071705
申请日：2013-11-05
申请人： Kirk P. Conrad , Sanjeev G. Shroff
发明人： Kirk P. Conrad , Sanjeev G. Shroff
IPC分类号： A61K38/22
CPC分类号： A61K38/2221 , A61B5/02007
摘要： The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
摘要翻译：本发明提供了增加动脉顺应性的方法。所述方法通常涉及向有需要的个体施用有效量的松弛素。本发明还提供了具有1型或2型糖尿病的个体中增加动脉顺应性的方法。本发明还提供了在绝经期，绝经期和绝经后妇女中增加动脉顺应性的方法。本发明进一步提供了增加具有或有风险发展年龄相关动脉僵硬的个体中的动脉顺应性的方法。

5. 发明授权

US07878978B2 Use of relaxin to increase arterial compliance 有权
标题翻译：使用松弛素增加动脉顺应性
公开(公告)号：US07878978B2
公开(公告)日：2011-02-01
申请号：US11084670
申请日：2005-03-18
申请人： Kirk P. Conrad , Sanjeev G. Shroff
发明人： Kirk P. Conrad , Sanjeev G. Shroff
IPC分类号： A61B5/00
CPC分类号： A61K38/2221 , A61B5/02007
摘要： The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
摘要翻译：本发明提供了增加动脉顺应性的方法。所述方法通常涉及向有需要的个体施用有效量的松弛素。本发明还提供了具有1型或2型糖尿病的个体中增加动脉顺应性的方法。本发明还提供了在绝经期，绝经期和绝经后妇女中增加动脉顺应性的方法。本发明进一步提供了增加具有或有风险发展年龄相关动脉僵硬的个体中的动脉顺应性的方法。

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