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    • 1. 发明授权
    • Use of relaxin to increase arterial compliance
    • 使用松弛素增加动脉顺应性
    • US08602998B2
    • 2013-12-10
    • US12985714
    • 2011-01-06
    • Kirk P ConradSanjeev G Shroff
    • Kirk P ConradSanjeev G Shroff
    • A61B5/00A61B5/02
    • A61K38/2221A61B5/02007
    • The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
    • 本发明提供了增加动脉顺应性的方法。 所述方法通常涉及向有需要的个体施用有效量的松弛素。 本发明还提供了具有1型或2型糖尿病的个体中增加动脉顺应性的方法。 本发明还提供了在绝经期,绝经期和绝经后妇女中增加动脉顺应性的方法。 本发明进一步提供了增加具有或有风险发展年龄相关动脉僵硬的个体中的动脉顺应性的方法。