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1. 发明授权

US5306842A Method of manufacturing aromatic urethanes 失效
标题翻译：制造芳香族聚氨酯的方法
公开(公告)号：US5306842A
公开(公告)日：1994-04-26
申请号：US875459
申请日：1992-04-29
申请人： Takao Ikariya , Masanori Itagaki , Masatsugu Mizuguchi , Makoto Miyazawa , Sachiko Yamamoto
发明人： Takao Ikariya , Masanori Itagaki , Masatsugu Mizuguchi , Makoto Miyazawa , Sachiko Yamamoto
IPC分类号： C07C269/00 , C07C269/04 , C07C273/18 , C07C271/00
CPC分类号： C07C269/04 , C07C269/00 , C07C273/1809
摘要： A method for manufacturing a purified aromatic urethane. Aromatic urethanes are synthesized from a N,N'-disubstituted urea and an organic hydroxyl compound in a reaction medium. The organic hydroxyl compound and the primary aromatic amine side product which are present in the reaction mixture is distilled off and removed from the reaction mixture leaving a distillation bottom. The N,N'-disubstituted urea is separated and removed from the distillation bottom by solvent extraction of the aromatic urethane, and the aromatic urethane in the extract phase obtained in said solvent extraction is separated and purified.
摘要翻译：纯化芳族聚氨酯的制造方法。芳族聚氨酯由N，N'-二取代的脲和有机羟基化合物在反应介质中合成。将存在于反应混合物中的有机羟基化合物和一级芳族胺副产物从反应混合物中蒸除并除去蒸馏塔底。通过芳族氨基甲酸酯的溶剂萃取，从蒸馏塔底部分离并除去N，N'-二取代的脲，分离和纯化在所述溶剂萃取中获得的萃取相中的芳族氨基甲酸酯。

2. 发明授权

US5130464A Method of manufacturing aromatic urethanes 失效
标题翻译：制造芳香尿布的方法
公开(公告)号：US5130464A
公开(公告)日：1992-07-14
申请号：US495353
申请日：1990-03-16
申请人： Takao Ikariya , Masanori Itagaki , Mikoto Iemoto , Masatsugu Mizuguchi , Tetsuo Hachiya , Tomomichi Nakamura , Makoto Miyazawa , Sachiko Yamamoto
发明人： Takao Ikariya , Masanori Itagaki , Mikoto Iemoto , Masatsugu Mizuguchi , Tetsuo Hachiya , Tomomichi Nakamura , Makoto Miyazawa , Sachiko Yamamoto
IPC分类号： C07C269/00 , C07C269/04 , C07C273/18
CPC分类号： C07C269/04 , C07C269/00 , C07C273/1809
摘要： A method of manufacturing aromatic urethanes utilizes a urea production process wherein a primary aromatic amine, an aromatic nitro-compound and carbon monoxide are made to react together in the presence of a catalyst and solvents, to produce N,N'-disubstituted urea, the solvlent used in the urea production process consisting at least partly of an amide or oxygen-containing sulfur compound, and having the functions of stabilizing the catalyst and preventing it from separating out in a solution, and of increasing the activity of the catalyst, the quantity of the solvent being sufficient to permit it to fulfill these functions effectively. The method additionally includes an aromatic urethane production process wherein the N,N'-disubstituted urea produced is made to react with an organic compound containing hydroxyl groups, to produce a primary aromatic amine and aromatic urethane, the primary aromatic amine being separated to obtain the aromatic urethane.

3. 发明申请

US20110052448A1 SPECIFIC COMPONENT MEASURING METHOD BY SPECTRAL MEASUREMENT 审中-公开
标题翻译：通过光谱测量的特定组件测量方法
公开(公告)号：US20110052448A1
公开(公告)日：2011-03-03
申请号：US12845130
申请日：2010-07-28
申请人： Takashi FUJITA , Sachiko YAMAMOTO , Hiroyuki YAMADA , Wataru AKAHANE
发明人： Takashi FUJITA , Sachiko YAMAMOTO , Hiroyuki YAMADA , Wataru AKAHANE
IPC分类号： G01N21/64 , G01N21/00
CPC分类号： G01N21/76 , G01N2201/023
摘要： The present invention discloses a method for measuring an amount of an objective component to be measured in a sample, which comprises; preventing an electric charge in an atmosphere in a photometry chamber from transferring to the surface of a solution which generates light due to an energy variation of a substance induced by the objective component in the sample, measuring value of the light, and determining an amount of the objective component in the sample on the basis of the measured value thus obtained, and an instrument used for the method.According to the present invention, in measurement of an objective component in a sample using a spectrophotometer, problems such as between-day variation of signal values or increase of background value, etc. can be solved, and a trace component can be measured in high accuracy and high sensitivity.
摘要翻译：本发明公开了一种测定样品中要测量的目标成分的量的方法，包括：防止测光室中的气氛中的电荷转移到由于样品中的目标成分引起的物质的能量变化而产生光的溶液的表面，测量光的量，基于由此获得的测量值的样品中的客观成分，以及用于该方法的仪器。根据本发明，在使用分光光度计测定样品中的目标成分的情况下，可以解决信号值的日间变化或背景值的增加等问题，并且可以高度地测量痕量成分精度高，灵敏度高。

4. 发明申请

US20060170914A1 Specific component measuring method by spectral measurement 失效
标题翻译：通过光谱测量的特定成分测量方法
公开(公告)号：US20060170914A1
公开(公告)日：2006-08-03
申请号：US10561538
申请日：2004-06-21
申请人： Takashi Fujita , Sachiko Yamamoto , Hiroyuki Yamada , Wataru Akahane
发明人： Takashi Fujita , Sachiko Yamamoto , Hiroyuki Yamada , Wataru Akahane
IPC分类号： G01N1/10
CPC分类号： G01N21/76 , G01N2201/023
摘要： The present invention discloses a method for measuring an amount of an objective component to be measured in a sample, which comprises; preventing an electric charge in an atmosphere in a photometry chamber from transferring to the surface of a solution which generates light due to an energy variation of a substance induced by the objective component in the sample, measuring value of the light, and determining an amount of the objective component in the sample on the basis of the measured value thus obtained, and an instrument used for the method. According to the present invention, in measurement of an objective component in a sample using a spectrophotometer, problems such as between-day variation of signal values or increase of background value, etc. can be solved, and a trace component can be measured in high accuracy and high sensitivity.
摘要翻译：本发明公开了一种测定样品中要测量的目标成分的量的方法，包括：防止测光室中的气氛中的电荷转移到由于样品中的目标成分引起的物质的能量变化而产生光的溶液的表面，测量光的量，基于由此获得的测量值的样品中的客观成分，以及用于该方法的仪器。根据本发明，在使用分光光度计测定样品中的目标成分的情况下，可以解决信号值的日间变化或背景值的增加等问题，并且可以高度地测量痕量成分精度高，灵敏度高。

5. 发明授权

US5854082A Process for measuring complement activity and reagent used therefor 失效
公开(公告)号：US5854082A
公开(公告)日：1998-12-29
申请号：US756363
申请日：1996-11-26
申请人： Kazuhisa Kubotsu , Sachiko Yamamoto , Masaaki Kida
发明人： Kazuhisa Kubotsu , Sachiko Yamamoto , Masaaki Kida
IPC分类号： G01N33/543 , G01N33/564 , G01N33/53
CPC分类号： G01N33/564 , G01N33/5432 , Y10S435/966 , Y10S435/967 , Y10S435/975 , Y10S436/821 , Y10S436/829
摘要： A reagent composition comprising (a) liposomes encapsulating a marker therein, immobilizing a hapten on liposome membranes and having a size in the range of 100 to 500 nm in terms of mean particle size plus twice the standard derivation, and (b) an antibody to the hapten is effective for measuring human complement activity easily and precisely with excellent storage stability.

6. 发明授权

US07795034B2 Specific component measuring method by spectral measurement 失效
标题翻译：通过光谱测量的特定成分测量方法
公开(公告)号：US07795034B2
公开(公告)日：2010-09-14
申请号：US10561538
申请日：2004-06-21
申请人： Takashi Fujita , Sachiko Yamamoto , Hiroyuki Yamada , Wataru Akahane
发明人： Takashi Fujita , Sachiko Yamamoto , Hiroyuki Yamada , Wataru Akahane
IPC分类号： G01N25/18
CPC分类号： G01N21/76 , G01N2201/023
摘要： The present invention discloses a method for measuring an amount of an objective component to be measured in a sample, which comprises; preventing an electric charge in an atmosphere in a photometry chamber from transferring to the surface of a solution which generates light due to an energy variation of a substance induced by the objective component in the sample, measuring value of the light, and determining an amount of the objective component in the sample on the basis of the measured value thus obtained, and an instrument used for the method.According to the present invention, in measurement of an objective component in a sample using a spectrophotometer, problems such as between-day variation of signal values or increase of background value, etc. can be solved, and a trace component can be measured in high accuracy and high sensitivity.
摘要翻译：本发明公开了一种用于测量样品中要测量的目标成分的量的方法，包括：防止测光室中的气氛中的电荷转移到由于样品中的目标成分引起的物质的能量变化而产生光的溶液的表面，测量光的量，基于由此获得的测量值的样品中的客观成分，以及用于该方法的仪器。根据本发明，在使用分光光度计测定样品中的目标成分的情况下，可以解决信号值的日间变化或背景值的增加等问题，并且可以高度地测量痕量成分精度高，灵敏度高。

7. 发明授权

US6015679A Process for measuring complement activity and reagent used therefor 失效
标题翻译：用于测量补体活性的方法和用于其的试剂
公开(公告)号：US6015679A
公开(公告)日：2000-01-18
申请号：US81675
申请日：1998-05-20
申请人： Kazuhisa Kubotsu , Sachiko Yamamoto , Masaaki Kida
发明人： Kazuhisa Kubotsu , Sachiko Yamamoto , Masaaki Kida
IPC分类号： G01N33/543 , G01N33/564 , G01N33/53
CPC分类号： G01N33/564 , G01N33/5432 , Y10S435/966 , Y10S435/967 , Y10S435/975 , Y10S436/821 , Y10S436/829
摘要： A reagent composition comprising (a) liposomes encapsulating a marker therein, immobilizing a hapten on liposome membranes and having a size in the range of 100 to 500 nm in terms of mean particle size plus twice the standard derivation, and (b) an antibody to the hapten is effective for measuring human complement activity easily and precisely with excellent storage stability.
摘要翻译：一种试剂组合物，其包含（a）在其中包封标记的脂质体，将半抗原固定在脂质体膜上，并且以平均粒径加上两倍于标准衍生物的尺寸在100至500nm范围内，和（b）抗体半抗原对于容易且准确地测量人补体活性是有效的，具有优异的储存稳定性。

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