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1. 发明专利

GB2479585A Adjustable foot-stool with infrared remote control 未知
公开(公告)号：GB2479585A
公开(公告)日：2011-10-19
申请号：GB201006349
申请日：2010-04-16
申请人： STEWART ALISON CAROLINE VIVIEN
发明人： STEWART ALISON CAROLINE VIVIEN
IPC分类号： A47C16/02
摘要： A foot-stool or foot-rest for comfort or physiotherapy comprises an internal motor to enable the height of the stool to be adjusted and is controlled by an infrared hand held remote control. A heated pad or cooling pack may be incorporated into the top of the stool. The top may also incorporate a massage unit or memory foam. Flip-up safety bars may be attached to the sides of the stool. The lifting mechanism may comprise a telescopic arm and a pair of metal strips pivoting at the centre to form a cross-shape. The motor may be powered by rechargable batteries.

2. 发明专利

GB201006349D0 Foot stool 未知
公开(公告)号：GB201006349D0
公开(公告)日：2010-06-02
申请号：GB201006349
申请日：2010-04-16
申请人： STEWART ALISON C V

3. 发明申请

WO2012049277A1 CXCR4 RECEPTOR ANTAGONISTS 审中-公开
标题翻译： CXCR4受体拮抗剂
公开(公告)号：WO2012049277A1
公开(公告)日：2012-04-19
申请号：PCT/EP2011/067946
申请日：2011-10-13
申请人： PROXIMAGEN LTD , BROWN, Giles , HIGGINBOTTOM, Michael , STEWART, Alison , PATIENT, Lee , CARLEY, Allison , SIMPSON, Iain , SAVORY, Edward Daniel , OLIVER, Kathryn , COLE, Andrew, Graham
发明人： BROWN, Giles , HIGGINBOTTOM, Michael , STEWART, Alison , PATIENT, Lee , CARLEY, Allison , SIMPSON, Iain , SAVORY, Edward Daniel , OLIVER, Kathryn , COLE, Andrew, Graham
IPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , A61K31/551 , A61P29/00
CPC分类号： C07D471/08 , A61K45/06 , C07B59/002 , C07B2200/05 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04
摘要： The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R 1 , X, Y and R 2 are as defined in the claims.
摘要翻译：式（I）化合物是CXCR4受体的拮抗剂，其中R1，X，Y和R2如权利要求中所定义。

4. 发明申请

WO2012112958A3 HIGH-THROUGHPUT ASSAYS TO PROBE LEUKEMIA WITHIN THE STROMAL NICHE 审中-公开
标题翻译：高通量测定探针在白细胞介素中的白血病
公开(公告)号：WO2012112958A3
公开(公告)日：2012-11-22
申请号：PCT/US2012025745
申请日：2012-02-17
申请人： BROAD INST INC , GEN HOSPITAL CORP , BRIGHAM & WOMENS HOSPITAL , HARVARD COLLEGE , SLOAN KETTERING INST CANCER , DANA FARBER CANCER INST INC , HARTWELL KIMBERLY , GILLILAND D GARY , MOORE MALCOME , SCADDEN DAVID , SCHREIBER STUART , GOLUB TODD , EBERT BENJAMIN , CARPENTER VAN DYK ANNE , LOGAN DAVID , STERN ANDREW , MILLER PETER , NEGRI JOSEPH , TOLLIDAY NICOLA , STEWART ALISON , SHAMJI ALYKHAN , MUKHERJEE SIDDHARTHA
发明人： HARTWELL KIMBERLY , GILLILAND D GARY , MOORE MALCOME , SCADDEN DAVID , SCHREIBER STUART , GOLUB TODD , EBERT BENJAMIN , CARPENTER VAN DYK ANNE , LOGAN DAVID , STERN ANDREW , MILLER PETER , NEGRI JOSEPH , TOLLIDAY NICOLA , STEWART ALISON , SHAMJI ALYKHAN , MUKHERJEE SIDDHARTHA
IPC分类号： G01N33/15 , C12N5/071 , G06T7/00
CPC分类号： G01N33/5011 , A61K31/167 , A61K31/22 , A61K31/366 , A61K31/395 , A61K31/405 , A61K31/4184 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/4418 , A61K31/444 , A61K31/4745 , A61K31/704 , A61K45/06
摘要： This invention relates to high-throughput, semi-automated methods for identifying compounds that are effective in targeting leukemia stem cells, as well as compounds identified by those methods and uses thereof for treating leukemia.
摘要翻译：本发明涉及用于鉴定有效靶向白血病干细胞的化合物的高通量，半自动化方法，以及通过这些方法鉴定的化合物及其用于治疗白血病的用途。

5. 发明申请

WO2012112958A2 HIGH-THROUGHPUT ASSAYS TO PROBE LEUKEMIA WITHIN THE STROMAL NICHE 审中-公开
标题翻译：高分辨率测量仪在探测器中探测亮片
公开(公告)号：WO2012112958A2
公开(公告)日：2012-08-23
申请号：PCT/US2012/025745
申请日：2012-02-17
申请人： THE BROAD INSTITUTE, INC , THE GENERAL HOSPITAL CORPORATION , THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , PRESIDENT AND FELLOWS OF HARVARD COLLEGE , SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH , DANA FARBER CANCER INSTITUTE, INC. , HARTWELL, Kimberly , GILLILAND, D. Gary , MOORE, Malcome , SCADDEN, David , SCHREIBER, Stuart , GOLUB, Todd , EBERT, Benjamin , CARPENTER VAN DYK, Anne , LOGAN, David , STERN, Andrew , MILLER, Peter , NEGRI, Joseph , TOLLIDAY, Nicola , STEWART, Alison , SHAMJI, Alykhan , MUKHERJEE, Siddhartha
发明人： HARTWELL, Kimberly , GILLILAND, D. Gary , MOORE, Malcome , SCADDEN, David , SCHREIBER, Stuart , GOLUB, Todd , EBERT, Benjamin , CARPENTER VAN DYK, Anne , LOGAN, David , STERN, Andrew , MILLER, Peter , NEGRI, Joseph , TOLLIDAY, Nicola , STEWART, Alison , SHAMJI, Alykhan , MUKHERJEE, Siddhartha
IPC分类号： G01N33/15 , C12N5/071 , G06T7/00
CPC分类号： G01N33/5011 , A61K31/167 , A61K31/22 , A61K31/366 , A61K31/395 , A61K31/405 , A61K31/4184 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/4418 , A61K31/444 , A61K31/4745 , A61K31/704 , A61K45/06
摘要： This invention relates to high-throughput, semi-automated methods for identifying compounds that are effective in targeting leukemia stem cells, as well as compounds identified by those methods and uses thereof for treating leukemia.
摘要翻译：本发明涉及用于鉴定有效靶向白血病干细胞的化合物的高通量半自动化方法，以及通过这些方法鉴定的化合物及其用于治疗白血病的用途。

6. 发明申请

WO2011113798A2 NEW ENZYME INHIBITOR COMPOUNDS 审中-公开
标题翻译：新型酶抑制剂化合物
公开(公告)号：WO2011113798A2
公开(公告)日：2011-09-22
申请号：PCT/EP2011053818
申请日：2011-03-14
申请人： PROXIMAGEN LTD , EVANS DAVID , CARLEY ALLISON , STEWART ALISON , HIGGINBOTTOM MICHAEL , SAVORY EDWARD , SIMPSON IAIN , NILSSON MARIANNE , HARALDSSON MARTIN , NORDLING ERIK , KOOLMEISTER TOBIAS
发明人： EVANS DAVID , CARLEY ALLISON , STEWART ALISON , HIGGINBOTTOM MICHAEL , SAVORY EDWARD , SIMPSON IAIN , NILSSON MARIANNE , HARALDSSON MARTIN , NORDLING ERIK , KOOLMEISTER TOBIAS
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D487/04 , C07D491/08 , C07D498/08 , C07D519/00
摘要： Compounds of formula (I) are inhibitors of Semicarbazide-sensitive amine oxidase wherein R1, A, X and R2 are as defined in the claims.
摘要翻译：式（I）化合物是氨基脲敏感性胺氧化酶的抑制剂，其中R1，A，X和R2如权利要求中所定义。

7. 发明申请

WO2009102222A1 METHODS AND COMPOSITIONS COMPRISING TRICHODERMA ATROVIRIDE FOR THE BIOLOGICAL CONTROL OF SOIL BORNE PLANT PATHOGENS AND PROMOTING PLANT GROWTH 审中-公开
标题翻译：包含
公开(公告)号：WO2009102222A1
公开(公告)日：2009-08-20
申请号：PCT/NZ2009/000015
申请日：2009-02-13
申请人： LINCOLN UNIVERSITY , STEWART, Alison
发明人： STEWART, Alison
IPC分类号： A01N63/04
CPC分类号： A01N63/04 , C12R1/885
摘要： The present invention relates to Trichoderma atroviride strains and their use as biological control agents or plant growth promoters. Methods and compositions for biological control of soil borne plant pathogens, and increasing plant yield using T. atroviride are also provided.
摘要翻译：本发明涉及叶绿体菌株及其作为生物防治剂或植物生长促进剂的用途。还提供了用于生物防治土壤植物病原体的方法和组合物，以及使用阿特罗里韦提高植物产量。

8. 发明申请

WO2013037411A1 NEW ENZYME INHIBITOR COMPOUNDS 审中-公开
标题翻译：新型酶抑制剂化合物
公开(公告)号：WO2013037411A1
公开(公告)日：2013-03-21
申请号：PCT/EP2011/065967
申请日：2011-09-14
申请人： PROXIMAGEN LIMITED , EVANS, David , CARLEY, Allison , STEWART, Alison , HIGGINBOTTOM, Michael , SAVORY, Edward , SIMPSON, Iain , NILSSON, Marianne , HARALDSSON, Martin , NORDLING, Erik , KOOLMEISTER, Tobias
发明人： EVANS, David , CARLEY, Allison , STEWART, Alison , HIGGINBOTTOM, Michael , SAVORY, Edward , SIMPSON, Iain , NILSSON, Marianne , HARALDSSON, Martin , NORDLING, Erik , KOOLMEISTER, Tobias
IPC分类号： C07D471/04 , A61K31/437
CPC分类号： C07D471/04
摘要： 2-{4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}ethan-1-amine; 3- aminopropyl 4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxylate; 1-{4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}-4- (dimethylamino)butan-1-one; 5-amino-1-{4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3- yl]piperidin-1-yl}pentan-1-one; N-(2-aminoethyl)-4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1-carboxamide; N-(3-aminopropyl)-4-[1-(4-chlorophenyl)-1H- pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxamide; 4-[1-(4-chlorophenyl)-1H-pyrrolo[2,3- c]pyridin-3-yl]-N-[3-(dimethylamino)propyl]piperidine-1-carboxamide; 1-({4-[1-(4- chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}carbonyl)piperazine; 4-({4-[1-(4- chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}carbonyl)morpholine; 1-({4-[1-(4- chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidin-1-yl}carbonyl)-1,4-diazepane; ethyl 1- [1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylate; ethyl 1-[1-(4- methylphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylate; 1-[1-(4- chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxylic acid; N-(2- aminoethyl)-1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidine-4-carboxamide; 4-({1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin-4 yl}carbonyl)morpholine; 1-({1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin- 4-yl}carbonyl)piperazine; {4-[1-(4-methylphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin- 3-yl}methanol; {4-[1-(4-methylphenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin-2-yl}methanol; [(3R)-4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholin-3- yl]methanol; methyl 4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]morpholine-3- carboxylate; N-(2-aminoethyl)-4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3- yl]morpholine-3-carboxamide; 2-{4-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3- yl]morpholin-3-yl}ethan-1-ol; methyl 1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3- yl]piperidine-2-carboxylate; N-(2-aminoethyl)-1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4- c]pyridin-3-yl]piperidine-2-carboxamide; 1-({1-[1-(4-chlorophenyl)-1H-pyrazolo[3,4- c]pyridin-3-yl]piperidin-2-yl}carbonyl)piperazine; 4-[1-(4-methylphenyl)-1H-pyrrolo[2,3- c]pyridin-3-yl]morpholine; 1-(4-chlorophenyl)-3-(piperidin-4-yl)-1H-pyrrolo[2,3-c]pyridin-4- ol; N-butyl-1-(4-chlorophenyl)-N-methyl-1H-pyrazolo[3,4-c]pyridin-3-amine; 1-[4- (fluoromethyl)phenyl]-3-(oxan-4-yl)-1H-pyrazolo[3,4-c]pyridine; and 3-({4-[1-(4- chlorophenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl]piperidin-1-yl}methyl)pyridine are useful for the inhibition of SSAO activity.
摘要翻译： 2- {4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-基}乙-1-胺; 4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-甲酸3-氨基丙酯; 1- {4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-基} -4-（二甲基氨基）丁-1-酮; 5-氨基-1- {4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-基}戊-1-酮; N-（2-氨基乙基）-4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-甲酰胺; N-（3-氨基丙基）-4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-甲酰胺; 4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基] -N- [3-（二甲基氨基）丙基]哌啶-1-甲酰胺; 1 - （{4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-基}羰基）哌嗪; 4 - （{4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-基}羰基）吗啉; 1 - （{4- [1-（4-氯苯基）-1H-吡咯并[2,3-c]吡啶-3-基]哌啶-1-基}羰基）-1,4-二氮杂环庚烷; 1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-4-甲酸乙酯; 1- [1-（4-甲基苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-4-甲酸乙酯; 1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-4-甲酸; N-（2-氨基乙基）-1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-4-甲酰胺; 4 - （{1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-4-基}羰基）吗啉; 1 - （{1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-4-基}羰基）哌嗪; {4- [1-（4-甲基苯基）-1H-吡唑并[3,4-c]吡啶-3-基]吗啉-3-基}甲醇; {4- [1-（4-甲基苯基）-1H-吡唑并[3,4-c]吡啶-3-基]吗啉-2-基}甲醇; [（3R）-4- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]吗啉-3-基]甲醇; 4- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]吗啉-3-羧酸甲酯; N-（2-氨基乙基）-4- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]吗啉-3-甲酰胺; 2- {4- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]吗啉-3-基}乙-1-醇; 1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-2-甲酸甲酯; N-（2-氨基乙基）-1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-2-甲酰胺; 1 - （{1- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-2-基}羰基）哌嗪; 4- [1-（4-甲基苯基）-1H-吡咯并[2,3-c]吡啶-3-基]吗啉; 1-（4-氯苯基）-3-（哌啶-4-基）-1H-吡咯并[2,3-c]吡啶-4-醇; N-丁基-1-（4-氯苯基）-N-甲基-1H-吡唑并[3,4-c]吡啶-3-胺; 1- [4-（氟甲基）苯基] -3-（氧代-4-基）-1H-吡唑并[3,4-c]吡啶; 和3 - （{4- [1-（4-氯苯基）-1H-吡唑并[3,4-c]吡啶-3-基]哌啶-1-基}甲基）吡啶可用于抑制SSAO活性。

9. 发明申请

WO2011113798A3 INHIBITORS OF SEMICARABAZIDE - SENSITIVE AMINE OXIDASE 审中-公开
公开(公告)号：WO2011113798A3
公开(公告)日：2011-09-22
申请号：PCT/EP2011/053818
申请日：2011-03-14
申请人： Proximagen Limited , EVANS, David , CARLEY, Allison , STEWART, Alison , HIGGINBOTTOM, Michael , SAVORY, Edward , SIMPSON, Iain , NILSSON, Marianne , HARALDSSON, Martin , NORDLING, Erik , KOOLMEISTER, Tobias
发明人： EVANS, David , CARLEY, Allison , STEWART, Alison , HIGGINBOTTOM, Michael , SAVORY, Edward , SIMPSON, Iain , NILSSON, Marianne , HARALDSSON, Martin , NORDLING, Erik , KOOLMEISTER, Tobias
IPC分类号： C07D471/04 , C07D487/04 , C07D498/08 , A61K31/437 , A61P35/00 , A61P37/06 , A61P11/08 , A61P25/28 , A61P9/10
摘要： Compounds of formula (I) are inhibitors of Semicarbazide-sensitive amine oxidase wherein R 1 , A, X and R 2 are as defined in the claims.

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