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1. 发明公开

EP3240726A1 ROTARY WING VTOL WITH FIXED WING FORWARD FLIGHT MODE 有权
标题翻译：带固定翼向前飞行模式的旋转翼垂直
公开(公告)号：EP3240726A1
公开(公告)日：2017-11-08
申请号：EP15876091.8
申请日：2015-12-28
申请人： Seale, Joseph B. , Sloan, Walker M.
发明人： Seale, Joseph B. , Sloan, Walker M.
IPC分类号： B64C27/24
摘要： An aircraft's two wings and joined thruster propellers or turbines serve as rotary wings in helicopter mode and as fixed wings in airplane mode. The thrusters along the wingspans or at the wing tips drive both rotary wing rotation and airplane flight. Large-angle controlled feathering about the pitch change axes of the left and right wings and thrusters allows them to rotate, relative to each other, between facing and thrusting forward in the same direction for airplane flight or facing and thrusting oppositely for helicopter flight. Optional controls include: helicopter cyclic and collective pitch; airplane roll by differential wing pitch; yaw by differential prop thrust; fuselage pitch by wing pitch change and prop thrust change interacting with an underslung craft e.g.; and fuselage yaw control independent of rotor rotation via a powered rotary mast coupling or a tail responsive to rotor downwash. A teetering rotor hub is a further option.

2. 发明授权

EP3240726B1 ROTARY WING VTOL WITH FIXED WING FORWARD FLIGHT MODE 有权
公开(公告)号：EP3240726B1
公开(公告)日：2020-08-05
申请号：EP15876091.8
申请日：2015-12-28
申请人： Seale, Joseph B. , Sloan, Walker M.
发明人： Seale, Joseph B. , Sloan, Walker M.
IPC分类号： B64C27/24 , B64C27/16 , B64C27/18 , B64C29/00

3. 发明申请

WO2009131883A3 METHOD AND APPARATUS FOR ANALYTE PROCESSING 审中-公开
标题翻译：分析方法和装置
公开(公告)号：WO2009131883A3
公开(公告)日：2010-05-06
申请号：PCT/US2009040716
申请日：2009-04-15
申请人： BIOSCALE INC , FALB PETER W , BRANCAZIO DAVID , FRANCE ERIC , MASTERS BRETT P , MILLER MICHAEL F , ORMSBY JOSHUA R , SLOAN WALKER
发明人： FALB PETER W , BRANCAZIO DAVID , FRANCE ERIC , MASTERS BRETT P , MILLER MICHAEL F , ORMSBY JOSHUA R , SLOAN WALKER
IPC分类号： B01L3/00 , G01N35/00
CPC分类号： G01N35/00029 , B01L3/5025 , B01L3/502715 , B01L3/502738 , B01L2200/025 , B01L2200/16 , B01L2300/0654 , B01L2300/0816 , B01L2400/0487 , B01L2400/0655 , G01N2035/00148 , Y10T29/49
摘要： A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.
摘要翻译：用于处理样品中分析物的系统包括仪器和墨盒。墨盒包括流体输入，输入和输出阀组件，处理装置，流体储存器和用于将样品从流体输入传送到流体储存器的通道。阀组件包括适于响应由仪器的可移动头组件施加的力而形成密封流体室的阀。每个流体储存器适于与排气泵接口构件配合和对准。阀组件包括围绕凹部的凹陷壁和围绕凹部和凹陷壁的阀组件壁。凹陷壁和阀组件壁适于与覆盖凹部，凹陷壁和阀组件壁的柔性薄片配合并密封。墨盒和仪器包括用于精细和粗略地对准具有部分墨盒的仪器组件的互补特征。

4. 发明申请

WO2004065543A2 DEVICES AND METHODS FOR RECOVERY OF A TARGET MOLECULE FROM A SAMPLE 审中-公开
标题翻译：从样品中回收目标分子的装置和方法
公开(公告)号：WO2004065543A2
公开(公告)日：2004-08-05
申请号：PCT/US2004/001041
申请日：2004-01-15
申请人： EXACT SCIENCES CORPORATION , WHITNEY, Duncan, H. , SLOAN, Walker, M., III , KIEFFER-HIGGINS, Stephen, G. , SHUBER, Anthony, P.
发明人： WHITNEY, Duncan, H. , SLOAN, Walker, M., III , KIEFFER-HIGGINS, Stephen, G. , SHUBER, Anthony, P.
IPC分类号： C12N
CPC分类号： C12N15/101
摘要： The invention relates to a device for recovering a target molecule from a biological sample. The device includes a first unit defining a chamber, and the chamber includes a first region for receiving a sample and a second region including at least one electrophoretic medium. The device includes a second unit extending from a first end to a second end, and the second unit is interfaceable with the first unit. A mesh structure is located at the second end of the second unit and is impregnated with an electrophoretic medium that includes copolymerized capture probes. The second region is located between the first region and the mesh structure when the first unit is interfaced with the second unit.
摘要翻译：本发明涉及用于从生物样品中回收靶分子的装置。该装置包括限定腔室的第一单元，并且腔室包括用于接收样品的第一区域和包括至少一个电泳介质的第二区域。该装置包括从第一端延伸到第二端的第二单元，并且第二单元可与第一单元接合。网状结构位于第二单元的第二端，并且用包含共聚的捕获探针的电泳介质浸渍。当第一单元与第二单元接口时，第二区域位于第一区域和网格结构之间。

5. 发明申请

WO2016109408A4 ROTARY WING VTOL WITH FIXED WING FORWARD FLIGHT MODE 审中-公开
标题翻译：带固定翼向前飞行模式的旋转翼垂直
公开(公告)号：WO2016109408A4
公开(公告)日：2016-08-18
申请号：PCT/US2015067630
申请日：2015-12-28
申请人： SEALE JOSEPH B , SLOAN WALKER M
发明人： SEALE JOSEPH B , SLOAN WALKER M
IPC分类号： B64C27/24
CPC分类号： B64C27/24 , B64C27/16 , B64C27/18 , B64C29/0033
摘要： An aircraft's two wings and joined thruster propellers or turbines serve as rotary wings in helicopter mode and as fixed wings in airplane mode. The thrusters along the wingspans or at the wing tips drive both rotary wing rotation and airplane flight. Large-angle controlled feathering about the pitch change axes of the left and right wings and thrusters allows them to rotate, relative to each other, between facing and thrusting forward in the same direction for airplane flight or facing and thrusting oppositely for helicopter flight. Optional controls include: helicopter cyclic and collective pitch; airplane roll by differential wing pitch; yaw by differential prop thrust; fuselage pitch by wing pitch change and prop thrust change interacting with an underslung craft e.g.; and fuselage yaw control independent of rotor rotation via a powered rotary mast coupling or a tail responsive to rotor downwash. A teetering rotor hub is a further option.
摘要翻译：飞机的两个机翼和连接的推进器螺旋桨或涡轮机在直升机模式下用作旋翼，在飞机模式下用作固定翼。沿着翼展或翼尖的推进器驱动旋翼旋转和飞机飞行。左右翼和推进器的俯仰变化轴线的大角度控制羽化使得它们能够相对于彼此在面向之间旋转，并且以相同的方向向前推动用于飞机飞行或面向并且相反地用于直升机飞行的推进。可选控制包括：直升机循环和集体俯仰; 飞机按不同的机翼间距滚动; 通过差动推力推力偏航; 机翼俯仰变化和支撑推力变化引起的机身俯仰变化与下垂飞行器相互作用。机身偏航控制与转子旋转无关，通过动力旋转式桅杆联轴器或尾翼响应转子下冲。蹒跚的转子轮毂是另一种选择。

6. 发明申请

WO2009131883A2 METHOD AND APPARATUS FOR ANALYTE PROCESSING 审中-公开
标题翻译：分析方法和装置
公开(公告)号：WO2009131883A2
公开(公告)日：2009-10-29
申请号：PCT/US2009/040716
申请日：2009-04-15
申请人： BIOSCALE, INC. , FALB, Peter, W. , BRANCAZIO, David , FRANCE, Eric , MASTERS, Brett, P. , MILLER, Michael, F. , ORMSBY, Joshua, R. , SLOAN, Walker
发明人： FALB, Peter, W. , BRANCAZIO, David , FRANCE, Eric , MASTERS, Brett, P. , MILLER, Michael, F. , ORMSBY, Joshua, R. , SLOAN, Walker
IPC分类号： B01L3/00 , G01N35/00
CPC分类号： G01N35/00029 , B01L3/5025 , B01L3/502715 , B01L3/502738 , B01L2200/025 , B01L2200/16 , B01L2300/0654 , B01L2300/0816 , B01L2400/0487 , B01L2400/0655 , G01N2035/00148 , Y10T29/49
摘要： A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.
摘要翻译：用于处理样品中分析物的系统包括仪器和墨盒。墨盒包括流体输入，输入和输出阀组件，处理装置，流体储存器和用于将样品从流体输入传送到流体储存器的通道。阀组件包括适于响应由仪器的可移动头组件施加的力而形成密封流体室的阀。每个流体储存器适于与排气泵接口构件配合和对准。阀组件包括围绕凹部的凹陷壁和围绕凹部和凹陷壁的阀组件壁。凹陷壁和阀组件壁适于与覆盖凹部，凹陷壁和阀组件壁的柔性薄片配合并密封。墨盒和仪器包括用于精细和粗略地对准具有部分墨盒的仪器组件的互补特征。

7. 发明申请

WO2016109408A1 ROTARY WING VTOL WITH FIXED WING FORWARD FLIGHT MODE 审中-公开
标题翻译：带有固定箭头的旋转翼型垂直起飞模式
公开(公告)号：WO2016109408A1
公开(公告)日：2016-07-07
申请号：PCT/US2015/067630
申请日：2015-12-28
申请人： SEALE, Joseph, B. , SLOAN, Walker, M.
发明人： SEALE, Joseph, B. , SLOAN, Walker, M.
IPC分类号： B64C27/24
CPC分类号： B64C27/24 , B64C27/16 , B64C27/18 , B64C29/0033
摘要： An aircraft's two wings and joined thruster propellers or turbines serve as rotary wings in helicopter mode and as fixed wings in airplane mode. The thrusters along the wingspans or at the wing tips drive both rotary wing rotation and airplane flight. Large-angle controlled feathering about the pitch change axes of the left and right wings and thrusters allows them to rotate, relative to each other, between facing and thrusting forward in the same direction for airplane flight or facing and thrusting oppositely for helicopter flight. Optional controls include: helicopter cyclic and collective pitch; airplane roll by differential wing pitch; yaw by differential prop thrust; fuselage pitch by wing pitch change and prop thrust change interacting with an underslung craft e.g.; and fuselage yaw control independent of rotor rotation via a powered rotary mast coupling or a tail responsive to rotor downwash. A teetering rotor hub is a further option.
摘要翻译：一架飞机的两个翼和联合的推进器螺旋桨或涡轮机作为直升机模式的旋转翼和飞机模式下的固定翼。沿翼展或翼尖的推进器驱动旋转翼旋转和飞机飞行。围绕左右翼和推进器的俯仰变化轴的大角度控制羽化使得它们能够相对于彼此在相同方向上向前推动以进行飞机飞行或相对于直升机飞行而相反地旋转。可选控制包括：直升机循环和集体音调; 飞行器通过差速机翼俯仰; 偏差由差速推力推力; 机翼间距通过机翼桨距改变和支撑推力变化与下冲的技术相互作用。和机身偏航控制，独立于转子旋转，通过动力旋转柱杆联轴器或响应于转子下冲洗的尾部。另一种选择是转向轮毂。

8. 发明申请

WO1993017090A1 APPARATUS FOR COLLECTION AND TRANSFER OF PARTICLES AND MANUFACTURE THEREOF 审中-公开
标题翻译：用于收集和转移颗粒及其制造的装置
公开(公告)号：WO1993017090A1
公开(公告)日：1993-09-02
申请号：PCT/US1993001658
申请日：1993-02-24
申请人： CYTYC CORPORATION , POLK, Lewis, T., Jr. , VARTANIAN, Hugh , BROWN, Phillip, P. , SLOAN, Walker, M., III
发明人： CYTYC CORPORATION
IPC分类号： C12M01/12
CPC分类号： B01D63/087 , B01D61/18 , B01D63/08 , B01D63/081 , B29C65/18 , B29C66/034 , B29C66/114 , B29C66/1222 , B29C66/1228 , B29C66/131 , B29C66/534 , B29C66/71 , B29C66/712 , B29C66/727 , B29C66/73711 , B29C66/73715 , B29C66/8242 , B29C66/8322 , B29C66/91231 , B29C66/91421 , B29C66/91431 , B29C66/922 , B29C66/9241 , B29C66/944 , Y10T436/25 , Y10T436/25375 , B29K2025/06 , B29K2069/00
摘要： A device for collecting particles, such as human cells, from a fluid sample, and for transferring the collected particles to a receiver, such as a glass microscope slide, provides substantially exact replication of the spatial distribution of the cells on the collection device. The device supports a surface-collecting filter on a tubular rim, with a precise degree of flatness, and fastens the filter in place at a mounting shoulder recessed below the rim. Distortions of the mounting shoulder or of the filter at the mounting shoulder, caused by securing the filter to the shoulder, are confined to the shoulder structure, and do not detract from the desired precision flatness of the filter and rim structure.
摘要翻译：用于从流体样品收集诸如人细胞的颗粒并将收集的颗粒转移到诸如玻璃显微镜载玻片的接收器的装置提供了在收集装置上的细胞的空间分布的基本精确的复制。该装置在管状轮辋上支撑表面收集过滤器，具有精确的平坦度，并将过滤器固定在嵌入轮辋下方的安装肩上。通过将过滤器固定到肩部而引起的安装肩部处的安装肩部或过滤器的变形被限制在肩部结构上，并且不会降低过滤器和轮辋结构的期望的精度平坦度。

9. 发明申请

WO2004065543A3 DEVICES AND METHOD FOR RECOVERY OF A TARGET MOLECULE FROM A SAMPLE 审中-公开
标题翻译：从样品中回收目标分子的装置和方法
公开(公告)号：WO2004065543A3
公开(公告)日：2004-12-23
申请号：PCT/US2004001041
申请日：2004-01-15
申请人： EXACT SCIENCES CORP , WHITNEY DUNCAN H , SLOAN WALKER M III , KIEFFER-HIGGINS STEPHEN G , SHUBER ANTHONY P
发明人： WHITNEY DUNCAN H , SLOAN WALKER M III , KIEFFER-HIGGINS STEPHEN G , SHUBER ANTHONY P
IPC分类号： C12N15/10 , G01N27/447 , B01L3/02 , C12Q1/68 , G01N1/34
CPC分类号： C12N15/101
摘要： The invention relates to a device for recovering a target molecule from a biological sample. The device includes a first unit defining a chamber, and the chamber includes a first region for receiving a sample and a second region including at least one electrophoretic medium. The device includes a second unit extending from a first end to a second end, and the second unit is interfaceable with the first unit. A mesh structure is located at the second end of the second unit and is impregnated with an electrophoretic medium that includes copolymerized capture probes. The second region is located between the first region and the mesh structure when the first unit is interfaced with the second unit.
摘要翻译：本发明涉及用于从生物样品中回收靶分子的装置。该装置包括限定腔室的第一单元，并且腔室包括用于接收样品的第一区域和包括至少一个电泳介质的第二区域。该装置包括从第一端延伸到第二端的第二单元，并且第二单元可与第一单元接合。网状结构位于第二单元的第二端，并且用包含共聚的捕获探针的电泳介质浸渍。当第一单元与第二单元接口时，第二区域位于第一区域和网格结构之间。

10. 发明专利

AU2015374294A1 Rotary wing VTOL with fixed wing forward flight mode 未知
公开(公告)号：AU2015374294A1
公开(公告)日：2017-08-17
申请号：AU2015374294
申请日：2015-12-28
申请人： SEALE JOSEPH B , SLOAN WALKER M
发明人： SEALE JOSEPH B , SLOAN WALKER M
IPC分类号： B64C27/24
摘要： An aircraft's two wings and joined thruster propellers or turbines serve as rotary wings in helicopter mode and as fixed wings in airplane mode. The thrusters along the wingspans or at the wing tips drive both rotary wing rotation and airplane flight. Large-angle controlled feathering about the pitch change axes of the left and right wings and thrusters allows them to rotate, relative to each other, between facing and thrusting forward in the same direction for airplane flight or facing and thrusting oppositely for helicopter flight. Optional controls include: helicopter cyclic and collective pitch; airplane roll by differential wing pitch; yaw by differential prop thrust; fuselage pitch by wing pitch change and prop thrust change interacting with an underslung craft e.g.; and fuselage yaw control independent of rotor rotation via a powered rotary mast coupling or a tail responsive to rotor downwash. A teetering rotor hub is a further option.

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