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1. 发明公开

EP2486706A1 NETWORK PATH DISCOVERY AND ANALYSIS 有权转让
标题翻译：网络路径检测和分析
公开(公告)号：EP2486706A1
公开(公告)日：2012-08-15
申请号：EP10822714.1
申请日：2010-10-07
申请人： Jeyachandran, Vinod , Natarajan, Pradeep , Shaw, James Mark , Uppalli, Raghavendra , Singh, Pradeep , OPNET Technologies, Inc.
发明人： Jeyachandran, Vinod , Natarajan, Pradeep , Shaw, James Mark , Uppalli, Raghavendra , Singh, Pradeep , OPNET Technologies, Inc.
IPC分类号： H04L12/56
CPC分类号： H04L41/12 , H04L41/0213
摘要： A network analysis system invokes an application specific, or source-destination specific, path discovery process. The application specific path discovery process determines the path(s) used by the application, collects performance data from the nodes along the path, and communicates this performance data to the network analysis system for subsequent performance analysis. The system may also maintain a database of prior network configurations to facilitate the identification of nodes that are off the path that may affect the current performance of the application. The system may also be specifically controlled so as to identify the path between any pair of specified nodes, and to optionally collect performance data associated with the path.

2. 发明申请

WO2011044384A1 NETWORK PATH DISCOVERY AND ANALYSIS 审中-公开
标题翻译：网络路径发现与分析
公开(公告)号：WO2011044384A1
公开(公告)日：2011-04-14
申请号：PCT/US2010/051859
申请日：2010-10-07
申请人： JEYACHANDRAN, Vinod , NATARAJAN, Pradeep , SHAW, James , UPPALLI, Raghavendra , SINGH, Pradeep , OPNET Technologies, Inc.
发明人： JEYACHANDRAN, Vinod , NATARAJAN, Pradeep , SHAW, James , UPPALLI, Raghavendra , SINGH, Pradeep
IPC分类号： H04L12/56
CPC分类号： H04L41/12 , H04L41/0213
摘要： A network analysis system invokes an application specific, or source-destination specific, path discovery process. The application specific path discovery process determines the path(s) used by the application, collects performance data from the nodes along the path, and communicates this performance data to the network analysis system for subsequent performance analysis. The system may also maintain a database of prior network configurations to facilitate the identification of nodes that are off the path that may affect the current performance of the application. The system may also be specifically controlled so as to identify the path between any pair of specified nodes, and to optionally collect performance data associated with the path.
摘要翻译：网络分析系统调用特定于应用程序或源特定路径的路径发现过程。应用程序特定路径发现过程确定应用程序使用的路径，从沿着路径的节点收集性能数据，并将该性能数据传达到网络分析系统以进行后续性能分析。系统还可以维护先前网络配置的数据库，以便于识别可能影响应用的当前性能的路径之外的节点。还可以特别地控制系统，以便识别任何一对指定节点之间的路径，并且可选地收集与该路径相关联的性能数据。

3. 发明申请

WO2008024976A3 INFERRING CONNECTIVITY AMONG NETWORK SEGMENTS IN THE ABSENCE OF CONFIGURATION INFORMATION 审中-公开
标题翻译：在配置信息不足的情况下，网络部分之间传播连接性
公开(公告)号：WO2008024976A3
公开(公告)日：2008-06-19
申请号：PCT/US2007076768
申请日：2007-08-24
申请人： SINGH PRADEEP , BARATHAN VENUPRAKASH
发明人： SINGH PRADEEP , BARATHAN VENUPRAKASH
IPC分类号： H04L12/24
CPC分类号： H04L41/12 , H04L41/0853 , H04L41/145 , H04L41/22
摘要： The present system includes a system, method and device for inferring connectivity between unconnected network segments. In operation, unconnected network segments are identified. Configuration data related to the unconnected network segments may be examined to facilitate inferring configuration data for an external network connected between the unconnected network segments. The inferred configuration data may be rendered, such as exported or visualized. The inferred configuration data may be related to a communication protocol and/or may be related to network bandwidth. The examined configuration data may be captured directly from one or more of the unconnected network segments and/or may be retrieved from a configuration data file, such as a network configuration model.
摘要翻译：本系统包括用于推断未连接网段之间的连接的系统，方法和设备。在操作中，识别出未连接的网段。可以检查与未连接的网段相关的配置数据，以便于推断连接在未连接的网段之间的外部网络的配置数据。可以呈现推断的配置数据，例如导出或可视化。推断的配置数据可以与通信协议相关和/或可以与网络带宽相关。所检查的配置数据可以直接从一个或多个未连接的网段获取和/或可以从诸如网络配置模型的配置数据文件中检索。

4. 发明申请

WO2003088914A3 METHODS OF INHIBITING AND TREATING BACTERIAL BIOFILMS BY METAL CHELATORS 审中-公开
公开(公告)号：WO2003088914A3
公开(公告)日：2003-10-30
申请号：PCT/US2003/012128
申请日：2003-04-18
申请人： THE UNIVERSITY OF IOWA RESEARCH FOUNDATION , SINGH, Pradeep, K. , WELSH, Michael, J. , GREENBERG, E., Peter
发明人： SINGH, Pradeep, K. , WELSH, Michael, J. , GREENBERG, E., Peter
IPC分类号： A61K38/40
摘要： The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.

5. 发明申请

WO2010046918A1 PURIFICATION OF SUPERCOILED PLASMID DNA 审中-公开
标题翻译：超滤PLASMID DNA的纯化
公开(公告)号：WO2010046918A1
公开(公告)日：2010-04-29
申请号：PCT/IN2009/000558
申请日：2009-10-08
申请人： V. B. MEDICARE PVT. LTD. , GUPTA, Munishwar, Nath , SINGH, Pradeep, K. , RAGHAVA, Smita
发明人： GUPTA, Munishwar, Nath , SINGH, Pradeep, K. , RAGHAVA, Smita
IPC分类号： C12P19/34 , C12N15/10
CPC分类号： C12N15/1003
摘要： This invention comprises a process of purifying supercoiled plasmid DNA of purity and characteristics required for use in a DNA vaccine or in Gene Therapy or in uses where high purity supercoiled plasmid DNA is required, from a genetically transformed bacterium over-expressing the said supercoiled plasmid and the supercoiled plasmid DNA prepared by a process of this invention and products containing supercoiled DNA made by a process of this invention. The process of this invention comprises selective precipitation from a cell lyste of all DNA and endotoxin except supercoiled DNA by free metal ions. The said impurity comprising plasmid isoforms (linear, relaxed), genomic DNA, RNA, and an endotoxin from a host cell. The method is illustrated by using Cu 2+ metal ions. The said Cu 2+ metal ions were added as CuSO 4 to reach to a final concentration of at least 0.5 M. The removal of metal ions is achieved by dialysis.
摘要翻译：本发明包括从过表达所述超螺旋质粒的遗传转化细菌中纯化在DNA疫苗中或基因治疗或需要高纯度超螺旋质粒DNA的用途中纯化和特征所需的超螺旋质粒DNA的方法，以及通过本发明方法制备的超螺旋质粒DNA和含有本发明方法制备的超螺旋DNA的产物。本发明的方法包括通过游离金属离子从超螺旋DNA除去所有DNA和内毒素的细胞裂解物的选择性沉淀。所述杂质包含来自宿主细胞的质粒同种型（线性，松弛），基因组DNA，RNA和内毒素。该方法通过使用Cu2 +金属离子来说明。将所述Cu 2+金属离子作为CuSO 4加入到达到至少0.5M的终浓度。通过透析去除金属离子。

6. 发明申请

WO2008021877A3 MAPPING OFF-NETWORK TRAFFIC TO AN ADMINISTERED NETWORK 审中-公开
标题翻译：将离线网络流量映射到已管理的网络
公开(公告)号：WO2008021877A3
公开(公告)日：2008-07-17
申请号：PCT/US2007075473
申请日：2007-08-08
申请人： OPNET TECHNOLOGIES INC , SINGH PRADEEP , HUNDLEY KENT , MANOWITZ DAVID , BOYD DAVID JAMES , GUPTA NISHANT , JEYACHANDRAN VINOD
发明人： SINGH PRADEEP , HUNDLEY KENT , MANOWITZ DAVID , BOYD DAVID JAMES , GUPTA NISHANT , JEYACHANDRAN VINOD
IPC分类号： H04L12/56
CPC分类号： H04L41/145 , H04L45/02 , H04L45/122 , H04L45/24 , H04L45/38
摘要： Traffic flows through an administered network from an off-network source and/or to an off-network destination are simulated and analyzed by selecting an ingress and/or egress node within the administered network, the ingress node capable of collecting traffic from an off-network source, and the egress node capable of routing traffic to an off-network destination. Traffic flow is mapped from the source or ingress node through the administered network to the egress node. The traffic flow may be simulated and analyzed. The ingress and/or egress nodes may be selected in a variety of ways.
摘要翻译：通过选择被管理网络内的入口和/或出口节点，模拟和分析从离网源和/或离网目的地流经被管理网络的流量，入口节点能够从离线网络收集流量，网络源和能够将流量路由到脱网目的地的出口节点。业务流从源或入口节点通过被管理网络映射到出口节点。交通流量可以被模拟和分析。入口和/或出口节点可以以各种方式来选择。

7. 发明申请

WO2008024976A2 INFERRING CONNECTIVITY AMONG NETWORK SEGMENTS IN THE ABSENCE OF CONFIGURATION INFORMATION 审中-公开
标题翻译：在缺乏配置信息的情况下导致网络部分之间的连通性
公开(公告)号：WO2008024976A2
公开(公告)日：2008-02-28
申请号：PCT/US2007/076768
申请日：2007-08-24
申请人： SINGH, Pradeep , BARATHAN, Venuprakash
发明人： SINGH, Pradeep , BARATHAN, Venuprakash
IPC分类号： H04L12/24
CPC分类号： H04L41/12 , H04L41/0853 , H04L41/145 , H04L41/22
摘要： The present system includes a system, method and device for inferring connectivity between unconnected network segments. In operation, unconnected network segments are identified. Configuration data related to the unconnected network segments may be examined to facilitate inferring configuration data for an external network connected between the unconnected network segments. The inferred configuration data may be rendered, such as exported or visualized. The inferred configuration data may be related to a communication protocol and/or may be related to network bandwidth. The examined configuration data may be captured directly from one or more of the unconnected network segments and/or may be retrieved from a configuration data file, such as a network configuration model.
摘要翻译：本系统包括用于推断未连接的网段之间的连通性的系统，方法和设备。在操作中，识别未连接的网段。可以检查与未连接的网段有关的配置数据，以便于推断连接在未连接的网段之间的外部网络的配置数据。推断的配置数据可以被渲染，例如导出或可视化。推断的配置数据可能涉及通信协议和/或可能与网络带宽有关。所检查的配置数据可以从一个或多个未连接的网段直接捕获和/或可以从诸如网络配置模型的配置数据文件中检索。

8. 发明申请

WO2008021877A2 MAPPING OFF-NETWORK TRAFFIC TO AN ADMINISTERED NETWORK 审中-公开
标题翻译：映射离线网络到管理网络的交互
公开(公告)号：WO2008021877A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/075473
申请日：2007-08-08
申请人： OPNET TECHNOLOGIES, INC. , SINGH, Pradeep , HUNDLEY, Kent , MANOWITZ, David , BOYD, David James , GUPTA, Nishant , JEYACHANDRAN, Vinod
发明人： SINGH, Pradeep , HUNDLEY, Kent , MANOWITZ, David , BOYD, David James , GUPTA, Nishant , JEYACHANDRAN, Vinod
IPC分类号： H04L12/26 , H04L12/24
CPC分类号： H04L41/145 , H04L45/02 , H04L45/122 , H04L45/24 , H04L45/38
摘要： Traffic flows through an administered network from an off-network source and/or to an off-network destination are simulated and analyzed by selecting an ingress and/or egress node within the administered network, the ingress node capable of collecting traffic from an off-network source, and the egress node capable of routing traffic to an off-network destination. Traffic flow is mapped from the source or ingress node through the administered network to the egress node. The traffic flow may be simulated and analyzed. The ingress and/or egress nodes may be selected in a variety of ways.
摘要翻译：通过选择管理的网络内的入口和/或出口节点来模拟和分析从网络外的源和/或离网目的地流经管理的网络的流量，所述入口节点能够从离线网络中收集流量，网络源和能够将流量路由到离网目的地的出口节点。业务流从源或入节点通过被管理网络映射到出口节点。可以模拟和分析交通流量。可以以各种方式来选择入口节点和/或出口节点。

9. 发明申请

WO2005055723A1 GALLIUM INHIBITS BIOFILM FORMATION 审中-公开
标题翻译： GALLIUM抑制生物膜形成
公开(公告)号：WO2005055723A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/040525
申请日：2004-12-03
申请人： THE UNIVERSITY OF IOWA RESEARCH FOUNDATION , THE UNITED STATES OF AMERICA AS REPRESENTED BY THEDEPARTEMENT OF VETERANS AFFAIRS , BRITIGAN, Bradley, E. , SINGH, Pradeep
发明人： BRITIGAN, Bradley, E. , SINGH, Pradeep
IPC分类号： A01N59/16
CPC分类号： A61L27/54 , A01N59/16 , A61K31/28 , A61K33/24 , A61L27/306 , A61L29/106 , A61L29/16 , A61L2300/102 , A61L2300/404
摘要： The present invention provides a gallium-containing composition for coating/impregnating a device or device surface to prevent biofilm growth formation. The present invention also provides a method of preventing or inhibiting biofilm growth formation. The present invention also provides methods for killing established biofilms.
摘要翻译：本发明提供了一种用于涂覆/浸渍装置或装置表面以防止生物膜生长形成的含镓组合物。本发明还提供了预防或抑制生物膜生长形成的方法。本发明还提供了杀死已建立的生物膜的方法。

10. 发明申请

WO2009029356A1 VERIFYING DATA CONSISTENCY AMONG MULTIPLE STRUCTURED FILES 审中-公开
标题翻译：在多个结构化文件中验证数据一致性
公开(公告)号：WO2009029356A1
公开(公告)日：2009-03-05
申请号：PCT/US2008/070561
申请日：2008-07-18
申请人： AGARWAL, Ankit , LAVANNIS, Mahesh , SINGH, Pradeep
发明人： AGARWAL, Ankit , LAVANNIS, Mahesh , SINGH, Pradeep
IPC分类号： G06F17/30
CPC分类号： G06F17/30067
摘要： A scalable comparison structure and methodology is provided that is suitable for comparing select data content in hundreds or thousands of files in an efficient manner. Section delimiters are defined to identify the sections of the files within which the select data content is located, and sets of unique sections are identified based on the select data content within the section. Thereafter, comparisons and reports are based on these unique content sections. If multiple files include a common set of data, a single unique content section is used to represent these multiple files. File groups are optionally defined, and different sets of select data content can be compared based on these file groups. The result of the comparison is presented in multiple hierarchical forms, including an identification of which files are different from each other, and an identification of the differences among the unique content segments.
摘要翻译：提供了可扩展的比较结构和方法，适用于以有效的方式比较数百或数千个文件中的选择数据内容。段定界符被定义为识别选择数据内容所在的文件的部分，并且基于该部分内的选择数据内容来识别唯一部分的集合。此后，比较和报告是基于这些独特的内容部分。如果多个文件包含一组通用数据，则使用单个唯一内容部分来表示这些多个文件。可选地定义文件组，并且可以基于这些文件组来比较不同组的选择数据内容。比较的结果以多种分层形式呈现，包括哪些文件彼此不同的标识以及唯一内容段之间的差异的识别。

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