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    • 4. 发明申请
    • METHOD OF STERILIZING PREFILLED SYRINGE MEDICINES
    • 灭菌注射液药物灭菌方法
    • WO1996005877A1
    • 1996-02-29
    • PCT/JP1995001644
    • 1995-08-21
    • EIKEN CHEMICAL CO., LTD.MATSUMOTO, YasuyukiSAITO, MasahiroMORIKAWA, JunjiTAKANO, Hiroshi
    • EIKEN CHEMICAL CO., LTD.
    • A61M05/31
    • A61L2/06A61L2/26A61M5/001
    • The invention provides a method of sterilizing a chemical and an injector in a prefilled syringe and keeping them in sterilized condition, said method comprising mounting a liquid leakage preventive cap (1) on a tip end of an injector (2) in a prefilled syringe, filled with a chemical and mounting a sliding plug (3) in an opening at a rear end of the injector to prevent liquid leakage of the prefilled syringe, securing the prefilled syringe, which mounts thereto the liquid leakage preventive cap (1) and the sliding plug (3), by means of a securing container (6), sealing the securing container (6), to which the prefilled syringe (2) is fixed, by means of a poromeric and bacteria impermeable nonwoven paper or fabric to sterilize a chemical (5) in the prefilled syringe (2), the prefilled syringe (2) and the securing container at the same time. The securing container (6) is enclosed by a bag-shaped nonwoven paper or fabric (7). Alternatively, the securing container (6) may have an opening, and the opening may be sealed by the nonwoven paper or fabric (11). According to the invention, it is possible to manufacture a prefilled syringe kit readily at low cost in a sterilized manner and keep the sterilized condition.
    • 本发明提供了一种在预充式注射器中对化学药剂和注射器进行灭菌并将其保持在灭菌状态的方法,所述方法包括将防漏液帽(1)安装在预充式注射器中的注射器(2)的末端上, 填充有化学品并将滑动塞(3)安装在喷射器后端的开口中,以防止预填充的注射器的液体泄漏,固定预充式注射器,该注射器安装在防漏液盖(1)上并滑动 通过固定容器(6)将塞子(3),借助于通孔和细菌不可渗透的非织造纸或织物将固定的预充式注射器(2)固定到其上的固定容器(6)进行灭菌 (5)在预充式注射器(2)中,预充式注射器(2)和固定容器同时进行。 固定容器(6)由袋状非织造纸或织物(7)包围。 或者,固定容器(6)可以具有开口,并且开口可以被非织造纸或织物(11)密封。 根据本发明,可以以无菌方式以低成本容易地制造预填充注射器套件并保持灭菌状态。