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1. 发明专利

CA164904A TRACK GAUGE 未知
公开(公告)号：CA164904A
公开(公告)日：1915-09-14
申请号：CA164904D
申请日：1915-05-05
申请人： HENINGTON RICHARD ABRAHAM
发明人： HENINGTON RICHARD ABRAHAM

2. 发明申请

WO2004027384A3 REAL-TIME DETECTION OF NUCLEIC ACID REACTIONS 审中-公开
标题翻译：实时检测核酸反应
公开(公告)号：WO2004027384A3
公开(公告)日：2004-11-11
申请号：PCT/US0329418
申请日：2003-09-17
申请人： PERKINELMER LIFE SCIENCES INC , JOSEPH RICHARD ABRAHAM , DIMEO JAMES JOSEPH
发明人： JOSEPH RICHARD ABRAHAM , DIMEO JAMES JOSEPH
IPC分类号： G01N21/64 , C12N15/09 , C12Q1/68 , G01N20060101 , G01N21/78
CPC分类号： C12Q1/6816 , C12Q1/6818 , C12Q1/686 , C12Q2563/137 , C12Q2563/107 , C12Q2561/113
摘要： A process is provided for using oligonucleotide to which a detectable moiety is attached post-synthesis. A metal-containing fluorescent compound affords real-time detection of nucleic acid elongation, amplification, or hybridization. The process is especially advantageous since a detectable moiety is readily attached to an existing oligonucleotide at an internal nucleotide, rather than being limited to attachment at a 3' or 5' terminus.
摘要翻译：提供了使用合成后可检测部分连接的寡核苷酸的方法。含金属荧光化合物提供核酸延伸，扩增或杂交的实时检测。该方法是特别有利的，因为可检测的部分容易地连接到内部核苷酸上的现有寡核苷酸，而不是限于在3'或5'末端附着。

3. 发明申请

WO2004027384A2 REAL-TIME DETECTION OF NUCLEIC ACID REACTIONS 审中-公开
标题翻译：实时检测核酸反应
公开(公告)号：WO2004027384A2
公开(公告)日：2004-04-01
申请号：PCT/US2003/029418
申请日：2003-09-17
申请人： PERKINELMER LIFE SCIENCES, INC. , JOSEPH, Richard, Abraham , DIMEO, James, Joseph
发明人： JOSEPH, Richard, Abraham , DIMEO, James, Joseph
IPC分类号： G01N
CPC分类号： C12Q1/6816 , C12Q1/6818 , C12Q1/686 , C12Q2563/137 , C12Q2563/107 , C12Q2561/113
摘要： A process is provided for using oligonucleotide to which a detectable moiety is attached post-synthesis. A metal-containing fluorescent compound affords real-time detection of nucleic acid elongation, amplification, or hybridization. The process is especially advantageous since a detectable moiety is readily attached to an existing oligonucleotide at an internal nucleotide, rather than being limited to attachment at a 3' or 5' terminus.
摘要翻译：提供了使用合成后可检测部分连接的寡核苷酸的方法。含金属的荧光化合物提供核酸延伸，扩增或杂交的实时检测。该过程是特别有利的，因为可检测部分容易以内部核苷酸连接到现有寡核苷酸上，而不限于在3'或5'末端附着。

4. 发明申请

US20060274916A1 Remote data access 审中-公开
公开(公告)号：US20060274916A1
公开(公告)日：2006-12-07
申请号：US11448178
申请日：2006-06-06
申请人： Chin Chan , Richard Abraham , Junghyun Park , Bruce Lee , Keith McClelland , Paul Hurd
发明人： Chin Chan , Richard Abraham , Junghyun Park , Bruce Lee , Keith McClelland , Paul Hurd
IPC分类号： G06K9/00 , G01N23/04
CPC分类号： G06Q10/08 , G06Q10/06 , G06Q50/26 , G06Q50/30
摘要： The application discloses a system and methods for remote access and analysis of data collected about items under inspection. The system includes a data collection station, that may include an X-ray scanner, that scans the items under inspection to obtain data about the items. The data is transmitted to one or more remote expert stations, where a remote expert analyzes the data to determine whether the item contains a potential threat, such as, for example, explosives or other contraband.

5. 发明授权

US06363623B1 Apparatus and method for spinning a work piece 有权
标题翻译：旋转工件的装置和方法
公开(公告)号：US06363623B1
公开(公告)日：2002-04-02
申请号：US09586207
申请日：2000-06-02
申请人： Richard Abraham
发明人： Richard Abraham
IPC分类号： F26B1730
CPC分类号： H01L21/68728 , H01L21/68785 , H01L21/68792
摘要： Apparatus for spinning a work piece such as a semiconductor wafer includes a work piece platform that is configured to be rotated about a central axis. Arrayed about the periphery of the platform is a plurality of spaced apart, symmetrically positioned work piece supports. Each of the supports includes a resilient bumper that serves both to support the work piece and as a friction brake to retard slippage of the work piece relative to the platform when the platform and work piece are rotating, and especially when the platform is accelerating or decelerating. Also arrayed about the periphery of the work piece platform is a plurality of work piece gripper assemblies configured to center the work piece in contact with the work piece supports when the platform is rotating. The gripper assemblies include a gripper finger that is configured to pivot about a pivot axis from a non work piece gripping position to a work piece gripping position in response to centrifugal force generated by the rotation of the platform. In the work piece gripping position the gripper finger contacts the edge of the work piece.
摘要翻译：用于纺丝诸如半导体晶片的工件的装置包括被构造为围绕中心轴线旋转的工件平台。围绕平台的周边排列有多个间隔开的对称定位的工件支撑件。每个支撑件包括弹性缓冲器，其用于支撑工件和作为摩擦制动器，以当平台和工件旋转时延迟工件相对于平台的滑动，特别是当平台正在加速或减速时。还围绕工件平台的周边排列的是多个工件夹持器组件，其被构造成当平台旋转时使工件与工件支撑件接触。夹持器组件包括夹持器手指，其构造成响应于由平台的旋转产生的离心力，围绕枢转轴线从非工件夹持位置枢转到工件夹紧位置。在工件夹持位置，夹爪指接触工件的边缘。

6. 发明授权

US6073738A Article of luggage having divider for opposing sections 失效
标题翻译：行李带有相应部分的分隔物
公开(公告)号：US6073738A
公开(公告)日：2000-06-13
申请号：US33809
申请日：1998-03-03
申请人： J. Richard Abraham , Hyun S. Kim
发明人： J. Richard Abraham , Hyun S. Kim
IPC分类号： A45C13/03 , A45C5/12 , A45C5/14 , A45C13/30
CPC分类号： A45C13/03
摘要： An upright suitcase includes a front section and an opposing rear section, each having an outer panel and a circumferential wall with a bottom edge and a plurality of free edges. The bottom edges are hingedly connected for movement of the opposing front and rear sections between an open position, in which access to the opposing sections is provided, and a closed position, in which all of the edges of the two circumferential walls are in juxtaposition. A zipper closure engages the opposing sections and selectively holds the free edges of the circumferential walls in juxtaposition. A divider panel is positioned within the upright suitcase to at least partially divide the opposing sections from each other when in the closed position. The divider panel has one end flexibly tethered to the rear circumferential wall and is movable into and out of the rear section. Slack connectors connected to the rear circumferential wall are positioned to selectively and flexibly connect the free end of the divider to the rear circumferential wall. Retainer straps connected to the rear section are positioned to engage the divider and draw it toward the outer panel of the rear section.
摘要翻译：一个直立的手提箱包括一个前部和一个相对的后部，每个具有一个外部面板和一个具有底部边缘和多个自由边缘的圆周壁。底部边缘被铰接地连接，用于相对的前部和后部的运动在其中设置有相对部分的通路的打开位置和闭合位置之间，其中两个圆周壁的所有边缘并置在该关闭位置。拉链封闭件与相对的部分相接合并且选择性地保持并列的圆周壁的自由边缘。分隔板定位在直立行李箱内，以在处于关闭位置时至少部分地将相对部分彼此分开。分隔板具有柔性地连接到后周壁的一端，并且可移动进出后部。连接到后周壁的松紧连接器被定位成选择性地并且柔性地将分隔器的自由端连接到后周壁。连接到后部的固定带被定位成接合分隔件并将其拉向后部的外板。

7. 发明授权

US5984326A Roller mechanism for container or cart 失效
公开(公告)号：US5984326A
公开(公告)日：1999-11-16
申请号：US668442
申请日：1996-06-19
申请人： J. Richard Abraham , Paolo M. B. Tiramani , John A. Bozak
发明人： J. Richard Abraham , Paolo M. B. Tiramani , John A. Bozak
IPC分类号： A45C5/14 , B62B3/02
CPC分类号： A45C5/14 , B62B5/02
摘要： A suitcase has first rollers mounted thereon to at least partially support the suitcase when in an upright position and to enable rolling movement of the suitcase across a surface. The first end of an arm is pivotally mounted to a rigid body portion of the suitcase. Second rollers are mounted about adjacent to the second end of the arm to enable rolling movement of the suitcase across the surface. A first link is pivotally mounted to the rigid body portion, and a second link is pivotally mounted to the first link and the arm. The arm is alternately retractable to a retracted position about adjacent to a rear panel of the suitcase, and deployable to a deployed position spaced outwardly from the rear panel. The first and second rollers cooperate to fully support the suitcase when the second rollers are deployed and the suitcase is in a rolling position. A push/pull handle is mounted on the suitcase to enable a user to roll the suitcase across the surface.

8. 发明授权

US06624140B1 Synthetic peptides with antimicrobial and endotoxin neutralizing properties for management of the sepsis syndrome 失效
标题翻译：具有抗菌和内毒素中和特性的合成肽用于治疗败血症综合征
公开(公告)号：US06624140B1
公开(公告)日：2003-09-23
申请号：US09493211
申请日：2000-01-28
申请人： Philip Richard Abraham , Bernard Jan Appelmelk , Sander Jan Hendrik Van Deventer
发明人： Philip Richard Abraham , Bernard Jan Appelmelk , Sander Jan Hendrik Van Deventer
IPC分类号： A01N3718
CPC分类号： G01N33/579 , A61K38/00 , C07K14/4723 , C07K14/4742 , Y02A50/411 , Y02A50/58
摘要： A peptide with an amino acid composition such that the peptide is amphipathic, cationic and forms a stable &agr;-helix and has the following structure comprising at least 12 amino acids R1-R2-A1-B1-(A2-B2-C1-A3)m-(C2)n-R3, wherein A=an amino acid selected from the basic amino acids Lys,Arg or His B=an amino acid selected from the aromatic amino acids Phe, Trp or Tyr C=an amino acid selected from the group comprising the hydrophobic amino acids Leu, Ile, Val or Ala, and said peptide has either the orientation according to the formula or the retro orientation thereof, wherein at least 0-m of the repetitive sequence motifs (A2-B2-C1-A3) have the retro orientation and the remaining repetitive motifs (A2-B2-C1-A3) have the orientation as presented in the formula and wherein, R1-R2- and R3 are a number of amino acids, and wherein m=1-10, preferably 2-8, more preferably 2-5 and n=1-3, a pharmaceutical composition comprising such a peptide application thereof in treatment or diagnosis related to i.a. parasite infection topical and systemic tumors and septic shock.
摘要翻译：具有氨基酸组成的肽，使得肽是两亲性的，阳离子的并形成稳定的α-螺旋，并且具有包含至少12个氨基酸的以下结构A =选自碱性氨基酸Lys，Arg或HisB =的氨基酸氨基酸选自芳族氨基酸Phe，Trp或TyrC =选自疏水性氨基酸Leu，Ile，Val或Ala的氨基酸，所述肽具有根据式的取向或其复古方向，其中至少0-m的重复序列基序（A2-B2-C1-A3）具有反向取向，并且其余的重复基序（A2-B2-C1-A3）具有如式中所示的取向，并且其中R1 -R2-和R3是多个氨基酸，并且其中m = 1-10，优选2-8，更优选2-5和n = 1-3，药物组合物包含其在治疗或诊断中的这种肽应用 ia 寄生虫感染局部和全身肿瘤和败血性休克。

9. 发明授权

US06446987B2 Roller mechanism for container or cart 失效
标题翻译：容器或推车的滚筒机构
公开(公告)号：US06446987B2
公开(公告)日：2002-09-10
申请号：US09441173
申请日：1999-11-15
申请人： J Richard Abraham , Paolo M. B. Tiramani , John A. Bozak
发明人： J Richard Abraham , Paolo M. B. Tiramani , John A. Bozak
IPC分类号： B62B302
CPC分类号： A45C5/14 , B62B5/02
摘要： A suitcase has first rollers mounted thereon to at least partially support the suitcase when in an upright position and to enable rolling movement of the suitcase across a surface. The first end of an arm is pivotally mounted to a rigid body portion of the suitcase. Second rollers are mounted about adjacent to the second end of the arm to enable rolling movement of the suitcase across the surface. A first link is pivotally mounted to the rigid body portion, and a second link is pivotally mounted to the first link and the arm. The arm is alternately retractable to a retracted position about adjacent to a rear panel of the suitcase, and deployable to a deployed position spaced outwardly from the rear panel. The first and second rollers cooperate to fully support the suitcase when the second rollers are deployed and the suitcase is in a rolling position. A push/pull handle is mounted on the suitcase to enable a user to roll the suitcase across the surface.
摘要翻译：手提箱具有安装在其上的第一辊，以便在直立位置时至少部分地支撑手提箱，并且能够使手提箱横过表面滚动移动。臂的第一端枢转地安装到手提箱的刚体部分。第二辊安装在靠近臂的第二端附近，以使手提箱能够横过表面滚动。第一连杆枢转地安装到刚体部分，第二连杆枢转地安装到第一连杆和臂上。手臂交替地可缩回到靠近行李箱的后面板的缩回位置，并且可展开到从后面板向外间隔开的展开位置。当第二辊被展开并且手提箱处于滚动位置时，第一和第二辊配合以完全支撑手提箱。推拉手柄安装在手提箱上，使用户能够将手提箱横过表面。

10. 发明授权

US1288200A Welted boot or shoe. 失效
标题翻译： WELTED BOOT或SHOE。
公开(公告)号：US1288200A
公开(公告)日：1918-12-17
申请号：US20835217
申请日：1917-12-22
申请人： RICHARD ABRAHAM L
发明人： RICHARD ABRAHAM L
CPC分类号： A43B9/06

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