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1. 发明授权

US06623638B2 Hemodialyzer having improved dialysate perfusion 有权
标题翻译：血液透析器具有改善的透析液灌注
公开(公告)号：US06623638B2
公开(公告)日：2003-09-23
申请号：US09871864
申请日：2001-06-01
申请人： Randolph H. Watkins , James S. Slepicka , Michael R. Prisco
发明人： Randolph H. Watkins , James S. Slepicka , Michael R. Prisco
IPC分类号： B01D6302
CPC分类号： B01D63/02 , A61M1/16 , A61M1/1627 , A61M2202/0498 , A61M2205/15 , B01D61/20 , B01D2313/10 , B01D2313/12 , B01D2313/21
摘要： A dialyzer is provided comprising a casing defining an interior and including a dialysate inlet and a dialysate outlet. A plurality of fibers are located in the interior of the casing and define a fiber bundle. A dialysate inlet fluid channel is provided in fluid communication with the dialysate inlet and includes a plurality of flutes that extend into a portion of the fiber bundles, the flutes define an opening for allowing dialysate to flow from the inlet fluid channel into the interior of the casing. Methods of providing dialysis are also provided.
摘要翻译：提供了透析器，其包括限定内部的壳体，并且包括透析液入口和透析液出口。多个纤维位于壳体的内部并限定纤维束。提供透析液入口流体通道与透析液入口流体连通，并且包括延伸到纤维束的一部分中的多个凹槽，凹槽限定开口，用于允许透析液从入口流体通道流入到内部套管。还提供了提供透析的方法。

2. 发明授权

US5106425A Method for maintaining a flammable solvent in a non-flammable environment 失效
标题翻译：在易燃环境中维持易燃溶剂的方法
公开(公告)号：US5106425A
公开(公告)日：1992-04-21
申请号：US659800
申请日：1991-02-22
申请人： Robert M. Sluga , Randolph H. Watkins , Jerry D. Fisher , Dennis C. Berry , Milo Eldridge
发明人： Robert M. Sluga , Randolph H. Watkins , Jerry D. Fisher , Dennis C. Berry , Milo Eldridge
IPC分类号： C23G5/04 , H05K3/26
CPC分类号： C23G5/04 , H05K3/26 , Y10S203/17
摘要： A method for maintaining a flammable solvent in a nonflammable environment involves covering the flammable solvent with a nonflammable vapor blanket provided by a nonflammable solvent, such that vapors from the flammable and nonflammable solvents form a nonflammable gaseous mixture in the blanket. Such a method is used in removal of both oil-based and polar contaminants to control the flammability potential of an alcohol solvent. An apparatus for cleaning articles using fluorocarbon and alcohol solvents includes a chamber having a plurality of compartments for containing the solvents and a bounded vapor space. At least one of the compartments contains liquid fluorocarbon and at least one other will contain liquid alcohol. The solvents voltalize into the bounded vapor space to provide a nonflammable vapor blanket over the alcohol-containing compartment. Volatilized alcohol is mixed with the volatilized fluorocarbon to form a nonflammable mixture which is purified and separated, and the recovered fluorocarbon can be reused in subsequent cleaning operations.
摘要翻译：将易燃溶剂保持在不可燃环境中的方法包括用不燃性溶剂提供的不可燃蒸汽床覆盖可燃溶剂，使得来自可燃和不可燃溶剂的蒸汽在橡皮布中形成不可燃气体混合物。这种方法用于除去油基和极性污染物以控制醇溶剂的可燃性潜力。使用碳氟化合物和醇溶剂清洁制品的装置包括具有多个用于容纳溶剂的隔室和有界蒸气空间的室。至少一个隔室含有液体碳氟化合物，至少另外一个将含有液态醇。溶剂挥发到有界的蒸汽空间中，以在含酒精的隔室上提供不可燃蒸气床。将挥发的醇与挥发的碳氟化合物混合以形成不可燃混合物，其被纯化和分离，并且回收的碳氟化合物可以在随后的清洁操作中重复使用。

3. 发明授权

US5637267A Connector for medical procedures and methods for manufacturing same 失效
标题翻译：用于医疗程序的连接器及其制造方法
公开(公告)号：US5637267A
公开(公告)日：1997-06-10
申请号：US432284
申请日：1995-05-01
申请人： Ying-Cheng Lo , Lecon Woo , Michael T. K. Ling , Sandra Wade , Eddie Chan , Randolph H. Watkins , Randy Murphey
发明人： Ying-Cheng Lo , Lecon Woo , Michael T. K. Ling , Sandra Wade , Eddie Chan , Randolph H. Watkins , Randy Murphey
IPC分类号： A61M1/28 , A61L2/10 , A61M1/14 , B29C71/00 , B29C71/02 , B29K27/12
CPC分类号： B29C71/02 , B29C71/0063 , B29K2027/12 , B29K2995/0026 , B29L2031/7546
摘要： A method is provided for creating a plastic component constructed, at least in part, from polychlorotrifluoroethylene, having improved properties. The method creates a component from a composition that has polychlorotrifluoroethylene, heats the component to a temperature that is greater than the melting point of the composition, and rapidly quenches the component in a cold medium.
摘要翻译：提供了一种用于产生至少部分由聚氯三氟乙烯构成的具有改进性能的塑料部件的方法。该方法由具有聚氯三氟乙烯的组合物产生组分，将组分加热至高于组合物熔点的温度，并在冷介质中快速淬灭组分。

4. 发明授权

US5114608A Method of cleaning hollow fiber components of a dialyzer with chloro fluorocarbon compositions stabilized by epoxidized fatty acid glycerides or esters 失效
标题翻译：通过环氧化的脂肪酸甘油酯或硫酸酯稳定的氯氟化碳组合物清洁中和纤维组分的方法
公开(公告)号：US5114608A
公开(公告)日：1992-05-19
申请号：US596880
申请日：1990-10-12
申请人： Robert M. Sluga , Randolph H. Watkins , Henry M. Gajewski , Jerry D. Fisher , Dennis C. Berry
发明人： Robert M. Sluga , Randolph H. Watkins , Henry M. Gajewski , Jerry D. Fisher , Dennis C. Berry
IPC分类号： A61M1/14 , C11D7/26 , C11D7/28 , C11D7/50 , C11D7/60 , C23G5/028
CPC分类号： C11D7/261 , C11D7/5018 , C11D7/5081 , C11D7/266 , C11D7/28
摘要： A method of stabilizing chlorofluorocarbon compositions thereby is provided. The stabilized composition comprises a chlorofluorocarbon and a sufficient amount of an epoxidized, generally high molecular weight stabilizer having an oxirane content sufficient to effectively stabilize the chlorofluorocarbon. The stabilizer is preferably an epoxidized oil having a molecular weight in the range of about 300 to about 1,500 and an oxirane content of at least about 4%. The method includes the step of adding a sufficient amount of such a stabilizer to the chloroflurocarbon composition. The chlorofluorocarbon composition typically comprises chlorofluoromethane, chlorofluoroethane, mixtures thereof or a chlorofluorocarbon-alcohol azeotropic solution. Also provided is an improved continuous dialyzer cleaning method utilizing the stabilized chlorofluorocarbon composition.
摘要翻译：提供了一种稳定氯氟烃组合物的方法。稳定的组合物包含氯氟烃和足量的具有足以有效稳定氯氟烃的环氧乙烷含量的环氧化，通常高分子量的稳定剂。稳定剂优选为分子量在约300至约1500的环氧化物油和至少约4％的环氧乙烷含量的环氧化油。该方法包括向氯氟烃组合物中加入足够量的这种稳定剂的步骤。氯氟烃组合物通常包括氯氟甲烷，氯氟乙烷，其混合物或氯氟烃 - 醇共沸溶液。还提供了利用稳定的氯氟烃组合物的改进的连续透析器清洗方法。

5. 发明授权

US08961789B2 Systems and methods for performing hemodialysis 有权
标题翻译：用于进行血液透析的系统和方法
公开(公告)号：US08961789B2
公开(公告)日：2015-02-24
申请号：US12338052
申请日：2008-12-18
申请人： Randolph H. Watkins , Steven J. Wurgler , Shincy Maliekkal , Sujatha Karoor , Katrina Smith
发明人： Randolph H. Watkins , Steven J. Wurgler , Shincy Maliekkal , Sujatha Karoor , Katrina Smith
IPC分类号： B01D63/00 , C02F1/44 , A61M1/34 , B01D63/16 , B01D65/08 , A61M1/26
CPC分类号： A61M1/1623 , A61M1/26 , A61M1/265 , A61M1/3472 , A61M1/3479 , B01D63/16 , B01D65/08 , B01D2315/02 , B01D2321/2033
摘要： Systems and methods for performing hemodialysis to remove metabolic waste from the blood of a patient are disclosed. The systems and methods preferably comprise at least one blood processing apparatus that receives whole blood from a patient. Cellular blood components are removed from the whole blood by hemofiltration, to provide filtered plasma comprising metabolic waste that is substantially reduced of blood cells. The cellular blood components may be returned to the patient. The filtered plasma comprising waste may be removed from the blood processing apparatus through a waste path for further processing in a separate apparatus, or in the same apparatus in a second stage processing procedure to remove metabolic waste components and excess water from the plasma by hemodialysis. At least one of the hemofiltration and hemodialysis processing apparatus comprises a Taylor vortex-enhanced separation apparatus.
摘要翻译：公开了用于进行血液透析以从患者的血液中除去代谢废物的系统和方法。该系统和方法优选地包括从患者接收全血的至少一个血液处理装置。通过血液滤过从全血中除去细胞血液成分，以提供包含基本上减少血细胞的代谢废物的过滤血浆。细胞血液成分可以返回给患者。包含废物的过滤等离子体可以通过废物路径从血液处理设备中除去，以便在单独的设备中进行进一步处理，或者在第二阶段处理过程中的相同装置中，通过血液透析从血浆中除去代谢废物成分和过量的水。血液透析和血液透析处理装置中的至少一个包括泰勒涡旋增强分离装置。

6. 发明授权

US5113883A Apparatus for cleaning objects with volatile solvents 失效
标题翻译：用挥发性溶剂清洗物体的装置
公开(公告)号：US5113883A
公开(公告)日：1992-05-19
申请号：US659806
申请日：1991-02-22
申请人： Robert M. Sluga , Randolph H. Watkins , Jerry D. Fisher , Dennis C. Berry , Milo Eldridge
发明人： Robert M. Sluga , Randolph H. Watkins , Jerry D. Fisher , Dennis C. Berry , Milo Eldridge
IPC分类号： C23G5/04 , H05K3/26
CPC分类号： C23G5/04 , H05K3/26
摘要： A method for maintaining a flammable solvent in a nonflammable environment involves covering the flammable solvent with a nonflammable vapor blanket provided by a nonflammable solvent, such that vapors from the flammable and nonflammable solvents form a nonflammable gaseous mixture in the blanket. Such a method is used in removal of both oil-based and polar contaminants to control the flammability potential of an alcohol solvent. An apparatus for cleaning articles using fluorocarbon and alcohol solvents includes a chamber having a plurality of compartments for containing the solvents and a bounded vapor space. At least one of the compartments contains liquid fluorocarbon and at least one other will contain liquid alcohol. The solvents voltalize into the bounded vapor space to provide a nonflammable vapor blanket over the alcohol-containing compartment. Volatilized alcohol is mixed with the volatilized fluorocarbon to form a nonflammable mixture which is purified and separated, and the recovered fluorocarbon can be reused in subsequent cleaning operations.
摘要翻译：将易燃溶剂保持在不可燃环境中的方法包括用不燃性溶剂提供的不可燃蒸气床覆盖可燃溶剂，使得来自可燃和不可燃溶剂的蒸气在橡皮布中形成不可燃气体混合物。这种方法用于除去油基和极性污染物以控制醇溶剂的可燃性潜力。使用碳氟化合物和醇溶剂清洁制品的装置包括具有多个用于容纳溶剂的隔室和有界蒸气空间的室。至少一个隔室含有液体碳氟化合物，至少另外一个将含有液态醇。溶剂挥发到有界的蒸汽空间中，以在含酒精的隔室上提供不可燃蒸气床。将挥发的醇与挥发的碳氟化合物混合以形成不可燃混合物，其被纯化和分离，并且回收的碳氟化合物可以在随后的清洁操作中重复使用。

7. 发明授权

US5082503A Method for removing contaminants from the surfaces of articles 失效
标题翻译：从物品表面去除污染物的方法
公开(公告)号：US5082503A
公开(公告)日：1992-01-21
申请号：US601229
申请日：1990-10-22
申请人： Robert M. Sluga , Randolph H. Watkins , Jerry D. Fisher , Dennis C. Berry , Milo Eldridge
发明人： Robert M. Sluga , Randolph H. Watkins , Jerry D. Fisher , Dennis C. Berry , Milo Eldridge
IPC分类号： B08B3/08 , C23G5/04 , H05K3/26
CPC分类号： C23G5/04 , H05K3/26
摘要： A method for maintaining a flammable solvent in a nonflammable environment involves covering the flammable solvent with a nonflammable vapor blanket provided by a nonflammable solvent, such that vapors from the flammable and nonflammable solvents form a nonflammable gaseous mixture in the blanket. Such a method is used in removal of both oil-based and polar contaminants to control the flammability potential of an alcohol solvent. An apparatus for cleaning articles using fluorocarbon and alcohol solvents includes a chamber having a plurality of compartments for containing the solvents and a bounded vapor space. At least one of the compartments contains liquid fluorocarbon and at least one other will contain liquid alcohol. The solvents voltalize into the bounded vapor space to provide a nonflammable vapor blanket over the alcohol-containing compartment. Volatilized alcohol is mixed with the volatilized fluorocarbon to form a nonflammable mixture which is purified and separated, and the recovered fluorocarbon can be reused in subsequent cleaning operations.
摘要翻译：将易燃溶剂保持在不可燃环境中的方法包括用不燃性溶剂提供的不可燃蒸汽床覆盖可燃溶剂，使得来自可燃和不可燃溶剂的蒸汽在橡皮布中形成不可燃气体混合物。这种方法用于除去油基和极性污染物以控制醇溶剂的可燃性潜力。使用碳氟化合物和醇溶剂清洁制品的装置包括具有多个用于容纳溶剂的隔室和有界蒸气空间的室。至少一个隔室含有液体碳氟化合物，至少另外一个将含有液态醇。溶剂挥发到有界的蒸汽空间中，以在含酒精的隔室上提供不可燃蒸气床。将挥发的醇与挥发的碳氟化合物混合以形成不可燃混合物，其被纯化和分离，并且回收的碳氟化合物可以在随后的清洁操作中重复使用。

8. 发明授权

US5192340A Hollow fiber filter cleaning system and more particularly to the control of emissions from solvent cleaning equipment 失效
标题翻译：中空纤维过滤器清洁系统，更特别是控制溶剂清洗设备的排放
公开(公告)号：US5192340A
公开(公告)日：1993-03-09
申请号：US839965
申请日：1992-02-21
申请人： David C. H. Grant , Randolph H. Watkins , Robert M. Sluga , Steven J. Wurgler , Gregory D. Mills , Dennis C. Berry , Jerry D. Fisher
发明人： David C. H. Grant , Randolph H. Watkins , Robert M. Sluga , Steven J. Wurgler , Gregory D. Mills , Dennis C. Berry , Jerry D. Fisher
IPC分类号： B01D5/00 , B01D19/00 , B01D53/00 , B01D63/02 , B01D65/02
CPC分类号： B01D53/005 , B01D19/0068 , B01D5/0054 , B01D63/021 , B01D65/02 , B01D2321/04 , B01D2321/16 , B01D2321/185
摘要： An emission control system for a fluid composition comprised of volatile constituents used to clean a hollow fiber filter or capillary flow dialyzer including a housing having a chamber for receiving the dialyzer, a control system is used for establishing a desired environment in the chamber, the dialyzer and the fibers, a separator operatively associated with the chamber for separating gas and liquid components of the fluid composition, a stripper connected to the separator for fractionating lower boiling point volatiles from the gas to return the higher boiling point volatiles to the fluid phase and yield a stripped or solvent humidified gas and a delivery system for routing the stripped gas to the chamber dialyzer and fibers as a drying agent.
摘要翻译：一种用于清洁中空纤维过滤器或毛细管流式透析器的挥发性组分的流体组合物的排放控制系统，包括具有用于接收透析器的室的壳体，控制系统用于在腔室中建立期望的环境，透析器并且纤维，与腔室可操作地相关联的用于分离流体组合物的气体和液体组分的分离器，连接到分离器的汽提器，用于从气体中分馏低沸点挥发物以将高沸点挥发物返回到流体相，并产生剥离或溶剂加湿的气体和用于将剥离的气体引导到腔室透析器和作为干燥剂的纤维的递送系统。

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