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1. 发明授权

US07696316B2 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, H1983, M1983, 38555 or 593 molecules and uses therefor 失效
标题翻译： 21910,5563,4505,2504,15977,14760,25501,17903,3720,21529,26176,26343,5666,18610,33217,26967，H1983，M1983,38555或593分子及其用途
公开(公告)号：US07696316B2
公开(公告)日：2010-04-13
申请号：US11583766
申请日：2006-10-19
申请人： Rosana Kapeller-Libermann , John Joseph Hunter , Rachel E. Meyers , Laura A. Rudolph-Owen , Rory A. J. Curtis , Peter J. Olandt , Fong-Ying Tsai , Katherine M. Galvin , Miyoung Chun , Mark J. Williamson , Inmaculada Silos-Santiago , Rajasekhar Bandaru
发明人： Rosana Kapeller-Libermann , John Joseph Hunter , Rachel E. Meyers , Laura A. Rudolph-Owen , Rory A. J. Curtis , Peter J. Olandt , Fong-Ying Tsai , Katherine M. Galvin , Miyoung Chun , Mark J. Williamson , Inmaculada Silos-Santiago , Rajasekhar Bandaru
IPC分类号： C07K14/00 , C07H21/04 , C12P21/04 , C12P21/06
CPC分类号： C07K14/47 , A01K2217/05 , C12N9/1235
摘要： The invention provides isolated nucleic acids molecules, designated 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 and 593 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 and 593 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 gene has been introduced or disrupted. The invention still further provides isolated 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 proteins, fusion proteins, antigenic peptides and anti-21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子，命名为21910,5663,55053,2504,15977,14760,25501,17903,3720,21529,26176,26343,5663,18610,33217,21967，h1983，m1983,38555和593核酸分子。本发明还提供反义核酸分子，含有21910,5663,55053,2504,15977,14760,25501,17903,3700,21529,26176,26343,5663,18610,33217,21967，h1983，m1983,3855的重组表达载体和593个核酸分子，其中引入了表达载体的宿主细胞，以及非人类转基因动物，其中21910,5663,5553,2504,15977,14760,25501,17903,3720,21529,26176，已经引入或破坏了18610,33217,21967，h1983，m1983,38555或593基因。本发明还进一步提供分离的21910,5563,4560,25501,17903,3720,21529,26176,26343,5663,18610,33217,21967，h1983，m1983,38555或593蛋白，融合蛋白，抗原肽和抗-19910,563634,55053,2504,15977,14760,25501,17903,3720,21529,26176,26343,56638,18610,33217,21967，h1983，m1983,38555或593抗体。还提供了利用本发明组合物的诊断和治疗方法。

2. 发明申请

US20090263860A1 Novel 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 molecules and uses therefor 失效
标题翻译：小分子13237,18480,2245,16228,7677,26320,46169,36166,16836,46867,21617,55562,39228,62088,4675,23155,26657,42755,32229,22325,46863和32252分子及其用途
公开(公告)号：US20090263860A1
公开(公告)日：2009-10-22
申请号：US11980299
申请日：2007-10-30
申请人： Rachel E. Meyers , Mark J. Williamson , Rosana Kapeller-Libermann , Kyle J. MacBeth , John Joseph Hunter , Laura A. Rudolph-Owen , Rajasekhar Bandaru , Fong-Ying Tsai
发明人： Rachel E. Meyers , Mark J. Williamson , Rosana Kapeller-Libermann , Kyle J. MacBeth , John Joseph Hunter , Laura A. Rudolph-Owen , Rajasekhar Bandaru , Fong-Ying Tsai
IPC分类号： C12P21/02 , C12N15/11 , C12N15/00 , C12N5/06
CPC分类号： C12N9/1205 , A01K2217/05 , A61K48/00 , C07K2319/00
摘要： The invention provides isolated nucleic acids molecules, designated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 gene has been introduced or disrupted. The invention still further provides isolated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 proteins, fusion proteins, antigenic peptides and anti-13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子，命名为13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,21657,42755,32229,22325,46863 和32252个核酸分子。本发明还提供反义核酸分子，重组表达载体，其含有13237,18480,2245,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,216575,42755,32229 ，22325,46863和32252核酸分子，其中引入了表达载体的宿主细胞，以及非人类转基因动物，其中13237,18480,2362,46169,3677,26320,46869,38166,16836,46867,21617,26173,26169，已经引入或破坏了55562,39228,62088,4675,23155,21657,42755,32229,22325,46863或32252基因。本发明还进一步提供分离的13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,21657,42755,32229,22325,46863或32252蛋白质，融合蛋白，抗原肽和抗-13237,18480,2225,16228,7677,26320,4619,33166,16836,46867,21617,55562,39228,62088,46745,23155,216547,42755,32229,22325,46863 或32252抗体。还提供了利用本发明组合物的诊断和治疗方法。

3. 发明申请

US20060088907A1 Novel 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 molecules and uses therefor 审中-公开
公开(公告)号：US20060088907A1
公开(公告)日：2006-04-27
申请号：US10370959
申请日：2003-02-20
申请人： Rachel Meyers , Mark Williamson , Rosana Kapeller-Libermann , Kyle MacBeth , John Hunter , Laura Rudolph-Owen , Rajasekhar Bandaru , Fong-Ying Tsai
发明人： Rachel Meyers , Mark Williamson , Rosana Kapeller-Libermann , Kyle MacBeth , John Hunter , Laura Rudolph-Owen , Rajasekhar Bandaru , Fong-Ying Tsai
IPC分类号： C07K14/705 , C12P21/02 , C12N5/06 , C07H21/04
CPC分类号： C12N9/1205 , A01K2217/05 , A61K48/00 , C07K2319/00
摘要： The invention provides isolated nucleic acids molecules, designated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 and 32252 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 gene has been introduced or disrupted. The invention still further provides isolated 13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 proteins, fusion proteins, antigenic peptides and anti-13237, 18480, 2245, 16228, 7677, 26320, 46619, 33166, 16836, 46867, 21617, 55562, 39228, 62088, 46745, 23155, 21657, 42755, 32229, 22325, 46863 or 32252 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

4. 发明申请

US20060040357A1 Novel nucleic acid sequences encoding melanoma associated antigen molecules, aminotransferase molecules, ATPase molecules, acyltransferase molecules, pyridoxal-phosphate dependant enzyme molecules and uses therefor 失效
公开(公告)号：US20060040357A1
公开(公告)日：2006-02-23
申请号：US11245400
申请日：2005-10-06
申请人： Rajasekhar Bandaru , Maria Glucksmann , Rachel Meyers , Laura Rudolph-Owen
发明人： Rajasekhar Bandaru , Maria Glucksmann , Rachel Meyers , Laura Rudolph-Owen
IPC分类号： C07H21/04 , C12P21/06 , C12N9/10 , C12N9/12
CPC分类号： G01N33/5743 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/47 , C07K14/4748 , C07K2319/00 , C12N9/1029 , C12N9/1096 , C12N9/14 , C12N9/90
摘要： The invention provides isolated nucleic acids molecules that encode novel polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a sequence of the invention has been introduced or disrupted. The invention still further provides isolated proteins, fusion proteins, antigenic peptides and antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

5. 发明授权

US06462187B1 22109, a novel human thioredoxin family member and uses thereof 失效
标题翻译： 22109，一种新型人硫氧还蛋白家族成员及其用途
公开(公告)号：US06462187B1
公开(公告)日：2002-10-08
申请号：US09882835
申请日：2001-06-15
申请人： Rajasekhar Bandaru
发明人： Rajasekhar Bandaru
IPC分类号： C07H2104
CPC分类号： C12N9/0036
摘要： The invention provides isolated nucleic acids molecules, designated 22109 nucleic acid molecules, which encode novel thioredoxin members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 22109 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 22109 gene has been introduced or disrupted. The invention still further provides isolated 22109 proteins, fusion proteins, antigenic peptides and anti-22109 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的硫氧还蛋白成员的分离的核酸分子，命名为22109核酸分子。本发明还提供了反义核酸分子，含有22109个核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及导入或破坏了22109基因的非人类转基因动物。本发明还进一步提供了分离的22109蛋白，融合蛋白，抗原肽和抗-22109抗体。还提供了利用本发明组合物的诊断方法。

6. 发明申请

US20070099230A1 Novel nucleic acid sequences encoding melanoma associated antigen molecules, aminotransferase molecles, ATPase molecules, acyltransferase molecules, pyridoxal-phosphate dependant enzyme molecules and uses therefor 审中-公开
标题翻译：编码黑素瘤相关抗原分子，氨基转移酶分子，ATP酶分子，酰基转移酶分子，吡哆醛 - 磷酸依赖性酶分子的新型核酸序列及其用途
公开(公告)号：US20070099230A1
公开(公告)日：2007-05-03
申请号：US11636665
申请日：2006-12-08
申请人： Rajasekhar Bandaru , Maria Glucksmann , Rachel Meyers , Laura Rudolph-Owen
发明人： Rajasekhar Bandaru , Maria Glucksmann , Rachel Meyers , Laura Rudolph-Owen
IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06 , C07K14/82
CPC分类号： G01N33/5743 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/47 , C07K14/4748 , C07K2319/00 , C12N9/1029 , C12N9/1096 , C12N9/14 , C12N9/90
摘要： The invention provides isolated nucleic acids molecules that encode novel polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a sequence of the invention has been introduced or disrupted. The invention still further provides isolated proteins, fusion proteins, antigenic peptides and antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新多肽的分离的核酸分子。本发明还提供了反义核酸分子，含有本发明的核酸分子的重组表达载体，已经引入了表达载体的宿主细胞，以及本发明的序列已被引入或破坏的非人类转基因动物。本发明还进一步提供分离的蛋白质，融合蛋白，抗原肽和抗体。还提供了利用本发明组合物的诊断方法。

7. 发明授权

US07078205B2 NUCLEIC ACID SEQUENCES ENCODING MELANOMA ASSOCIATED ANTIGEN MOLECULES, AMINOTRANSFERASE MOLECULES, ATPASE MOLECULES, ACYLTRANSFERASE MOLECULES, PYRIDOXAL-PHOSPHATE DEPENDENT ENZYME MOLECULES AND USES THEREFOR 失效
标题翻译：核酸序列编码相关抗原分子，氨基转移酶分子，ATPase分子，ACYLTRANSFERASE分子，依赖于磷酸的磷酸酯依赖性酶分子及其用途
公开(公告)号：US07078205B2
公开(公告)日：2006-07-18
申请号：US10164966
申请日：2002-06-07
申请人： Rajasekhar Bandaru , Maria Alexandra Glucksmann , Rachel E. Meyers , Laura A. Rudolph-Owen
发明人： Rajasekhar Bandaru , Maria Alexandra Glucksmann , Rachel E. Meyers , Laura A. Rudolph-Owen
IPC分类号： C12N9/10 , C12N15/00 , C12N1/20 , C12N5/00 , C07H21/04
CPC分类号： G01N33/5743 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/47 , C07K14/4748 , C07K2319/00 , C12N9/1029 , C12N9/1096 , C12N9/14 , C12N9/90
摘要： The invention provides isolated nucleic acids molecules that encode novel polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a sequence of the invention has been introduced or disrupted. The invention still further provides isolated proteins, fusion proteins, antigenic peptides and antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新多肽的分离的核酸分子。本发明还提供了反义核酸分子，含有本发明的核酸分子的重组表达载体，已经引入了表达载体的宿主细胞，以及本发明的序列已被引入或破坏的非人类转基因动物。本发明还进一步提供分离的蛋白质，融合蛋白，抗原肽和抗体。还提供了利用本发明组合物的诊断方法。

8. 发明申请

US20090068187A1 Novel 14275, 54420, 8797, 27439, 68730, 69112 and 52908 molecules and uses therefor 审中-公开
标题翻译：小分子14275,5420,8797,27439,66830,69112和52908分子及其用途
公开(公告)号：US20090068187A1
公开(公告)日：2009-03-12
申请号：US11903752
申请日：2007-09-24
申请人： Maria A. Glucksmann , Rory A.J. Curtis , Fong-Ying Tsai , Martin R. Hodge , Rachel E. Meyers , Kyle J. MacBeth , Rajasekhar Bandaru
发明人： Maria A. Glucksmann , Rory A.J. Curtis , Fong-Ying Tsai , Martin R. Hodge , Rachel E. Meyers , Kyle J. MacBeth , Rajasekhar Bandaru
IPC分类号： A61K39/395 , C07H21/04 , C12N5/10 , C07K14/705 , C07K16/28 , C12P21/02 , C12Q1/68 , A61K31/7088 , A61K38/17 , G01N33/567 , G01N33/68 , C12N5/06 , C07K1/113 , A61K38/02
CPC分类号： C07K14/705 , A01K2217/05 , A61K38/00 , A61K48/00 , A61K2039/505 , C07K2319/00 , C07K2319/02 , C12N9/0071 , C12N9/1051 , C12N9/1205
摘要： The invention provides isolated nucleic acids molecules, designated 14275, 54420, 8797, 27439, 68730, 69112 or 52908 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 14275, 54420, 8797, 27439, 68730, 69112 or 52908 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 14275, 54420, 8797, 27439, 68730, 69112 or 52908 gene has been introduced or disrupted. The invention still further provides isolated 14275, 54420, 8797, 27439, 68730, 69112 or 52908 proteins, fusion proteins, antigenic peptides and anti-14275, 54420, 8797, 27439, 68730, 69112 or 52908 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子，命名为14275,54420,8797,27439,67830,69112或52908核酸分子。本发明还提供反义核酸分子，含有14275,54420,8797,27439,67830,69112或52908核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及非人类转基因动物，其中14275， 54420,8797,27439,67830,69112或52908基因被引入或破坏。本发明还进一步提供分离的14275,54420,8797,27439,68730,69112或52908蛋白，融合蛋白，抗原肽和抗-14275,54420,8797,27439,68730,69112或52908抗体。还提供了利用本发明组合物的诊断和治疗方法。

9. 发明申请

US20050214893A1 Novel human genes and methods of use thereof 审中-公开
标题翻译：新型人类基因及其使用方法
公开(公告)号：US20050214893A1
公开(公告)日：2005-09-29
申请号：US10968812
申请日：2004-10-19
申请人： Rachel Meyers , Rory Curtis , Maria Glucksmann , Rajasekhar Bandaru , Rosana Kapeller-Libermann
发明人： Rachel Meyers , Rory Curtis , Maria Glucksmann , Rajasekhar Bandaru , Rosana Kapeller-Libermann
IPC分类号： A61K38/00 , C07K14/47 , C07K14/705 , C12N9/02 , C12N9/10 , C12N9/48 , C12N9/90 , C12Q1/26 , G01N33/574
CPC分类号： C12N9/0004 , A61K38/00 , C07K14/47 , C07K14/4702 , C07K14/705 , C12N9/1048 , C12N9/48 , C12N9/90 , G01N33/57411 , G01N2500/04
摘要： The invention provides isolated nucleic acids molecules, designated 47476, 67210, 49875,46842,33201, 83378,84233,64708, 85041,84234,21617, 55562,23566,33489, and 57779 nucleic acid molecules, which encode novel human genes. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 gene has been introduced or disrupted. The invention still further provides isolated 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 proteins, fusion proteins, antigenic peptides and anti-47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的人基因的分离的核酸分子，命名为47476,67210,49875,46842,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489和57779核酸分子。本发明还提供反义核酸分子，包含47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,161617,55562,23566,33489或57779核酸分子的重组表达载体，宿主细胞已经引入了表达载体的非人类转基因动物，以及引入了47476,67210,49875,4642,43708,85041,84234,16617,55562,23566,33489或57779基因的非人类转基因动物，或中断了本发明还进一步提供分离的47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489或57779号蛋白，融合蛋白，抗原肽和抗-47476,67210， 49875,4462,33201,83378,84233,66708,85041,84234,21617,55562,253566,33489或57779抗体。还提供了利用本发明组合物的诊断方法。

10. 发明申请

US20080234468A1 Novel 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 molecules and uses therefor 失效
标题翻译：小分子27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577分子及其用途
公开(公告)号：US20080234468A1
公开(公告)日：2008-09-25
申请号：US11981466
申请日：2007-10-31
申请人： Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
发明人： Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Weich , Rajasekhar Bandaru
IPC分类号： C07K14/00
CPC分类号： A61K38/16 , A01K2217/05 , A61K38/4813 , A61K39/00 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12N9/0008 , C12N9/12 , C12N9/16 , C12N9/20 , C12N9/6416 , C12N9/6424 , C12N9/6491 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Y603/02019 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/573 , G01N33/68 , G01N2500/10 , Y10T436/143333 , A61K2300/00
摘要： The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子，命名为27877,18080,14081,32140,50352,16658,14223,16002,50566,65552和65577核酸分子。本发明还提供反义核酸分子，含有27877,18080,14081,32140,50502,16658,14223,16002,50566,65552和65577核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及已经引入或破坏了27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577基因的非人类转基因动物。本发明还进一步提供分离的27877,18080,14081,32140,50352,16658,14223,16002,50566,65552或65577蛋白，融合蛋白，抗原肽和抗27877,18080,14081,32140,50352,16658,14223 ，16002,50566,65552或65577抗体。还提供了利用本发明组合物的诊断和治疗方法。

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