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1. 发明公开

EP2606851A1 Preloaded Wire for Endoluminal Device 有权
标题翻译： Vorgespannter Drahtfürendoluminale Vorrichtung
公开(公告)号：EP2606851A1
公开(公告)日：2013-06-26
申请号：EP12197881.1
申请日：2012-12-18
申请人： Roeder, Blayne A. , Huser, Matthew S. , Coverdale, Kelly
发明人： Roeder, Blayne A. , Huser, Matthew S. , Coverdale, Kelly
IPC分类号： A61F2/07
CPC分类号： A61F2/07 , A61F2/89 , A61F2/954 , A61F2002/061 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2220/005 , A61F2220/0075 , A61F2230/001
摘要： A system includes an endoluminal prosthesis and a guide wire. The prosthesis includes a tubular body including a graft material wall, proximal and distal end openings, a lumen, and first, second, third, and fourth fenestrations in the wall. The first and second fenestrations may be spaced circumferentially. The third and fourth fenestrations may be spaced circumferentially and positioned distal of the first and second fenestrations. First and second branches may extend from the tubular body and be in fluid communication with the third and fourth fenestrations, respectively. The guide wire may have first and second ends extending proximal of the proximal end opening. The guide wire may enter the proximal end opening, exit the first fenestration, partially traverse an exterior surface of the prosthesis, enter the second fenestration, and exit the proximal end opening. No portion of the guide wire may extend distally beyond the distal end opening.
摘要翻译：系统包括腔内假体和导丝。假体包括管状体，其包括移植材料壁，近端和远端开口，内腔和壁中的第一，第二，第三和第四开窗。第一和第二开窗可以沿圆周方向间隔开。第三和第四开窗可以沿周向间隔开并定位在第一和第二开窗的远侧。第一和第二分支可以从管状体延伸并分别与第三和第四开窗孔流体连通。引导线可以具有在近端开口的近侧延伸的第一端和第二端。导丝可以进入近端开口，离开第一开窗，部分地穿过假体的外表面，进入第二开窗并离开近端开口。导丝的任何部分可以向远端延伸超过远端开口。

2. 发明公开

EP2517671A3 Apparatus for facilitating deployment of an endoluminal prosthesis 有权转让
标题翻译：用于促进腔内假体的插入的装置
公开(公告)号：EP2517671A3
公开(公告)日：2013-05-15
申请号：EP12164809.1
申请日：2012-04-19
申请人： Greenberg, Roy K. , West, Karl J. , Resch, Timothy A. , Roeder, Blayne A.
发明人： Greenberg, Roy K. , West, Karl J. , Resch, Timothy A. , Roeder, Blayne A.
IPC分类号： A61F2/06 , A61F2/84
CPC分类号： A61F2/07 , A61F2/06 , A61F2/82 , A61F2/86 , A61F2/89 , A61F2/95 , A61F2/954 , A61F2/962 , A61F2002/061 , A61F2002/072 , A61F2002/075 , A61F2002/821 , A61F2002/826 , A61F2002/9665 , A61F2220/0075 , A61F2230/0091 , A61F2250/0007 , A61F2250/0017 , A61F2250/0018 , A61F2250/0039
摘要： A system for facilitating deployment of an endoluminal prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. A wire segment may include a proximal portion positioned proximal of the proximal end opening and a distal portion positioned distal of the distal end opening. The wire segment extend through the fenestration and through the lumen of the branch in a preloaded configuration.

3. 发明公开

EP2409655A2 False lumen occluder 有权转让
标题翻译： Okkluderfürein falsches Lumen
公开(公告)号：EP2409655A2
公开(公告)日：2012-01-25
申请号：EP11174324.1
申请日：2011-07-18
申请人： Gopalakrishnamurthy, Sharath , Kratzberg, Jarin , Purdy, James D. , Roeder, Blayne A. , Charlebois, Steven J.
发明人： Gopalakrishnamurthy, Sharath , Kratzberg, Jarin , Purdy, James D. , Roeder, Blayne A. , Charlebois, Steven J.
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12172
摘要： An endoluminal device (10) for repairing an aortic dissection and preventing future aortic dissections, the device including a plurality of struts (16) with at least one of the plurality of struts having a mid-strut portion (22) having two more secondary struts (24), the device being configured to be secured within a false lumen of the aorta and contain filler material in order to encourage thrombosis within the false lumen.
摘要翻译：一种用于修复主动脉夹层并防止未来主动脉夹层的腔内装置（10），所述装置包括多个支柱（16），所述多个支柱中的至少一个支柱具有中间支柱部分（22），所述中间支柱部分具有两个以上的第二支柱（24），所述装置被配置为固定在主动脉的假腔中并且包含填充材料以便促进假腔内的血栓形成。

4. 发明公开

EP2489331A3 Stent structures for use with valve replacement 有权转让
公开(公告)号：EP2489331A3
公开(公告)日：2012-11-07
申请号：EP11275139.1
申请日：2011-11-04
申请人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
发明人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2220/0016 , A61F2230/0019 , A61F2230/0078
摘要： A medical device for implantation in a patient comprises a stent (20) and a valve (120). The stent (20) comprises a proximal region (30) comprising a cylindrical shape having a first outer diameter when the stent is in an expanded state, and a distal region (70) comprising a cylindrical shape having a second outer diameter when the stent is in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve (130) is at least partially positioned within the proximal region of the stent, and the distal region (140) of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.

5. 发明公开

EP2478869A1 Aortic valve prosthesis 有权转让
标题翻译： Aortenklappenprothese
公开(公告)号：EP2478869A1
公开(公告)日：2012-07-25
申请号：EP11275138.3
申请日：2011-11-04
申请人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
发明人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2250/0029
摘要： A valve (120) for implantation in a patient comprises a proximal region (130) comprising a cylindrical shape, and a distal region (170) having a generally rectangular shape comprising opposing flat surfaces (172, 174) that are separated by narrower flat sides (175a, 175b). A tapered region (150) is disposed between the proximal and distal regions, where the tapered region comprises two opposing flat surfaces (152, 154) that transition into the opposing flat surfaces of the distal region. The opposing flat surfaces of the tapered region are angled relative to the proximal and distal regions. The opposing flat surfaces at the distal end of the valve allow fluid flow therethrough during antegrade flow and are generally adjacent to one another to inhibit blood flow through the valve during retrograde flow. Optionally, at least one reinforcement member (185) may be coupled to the valve to prevent prolapse of the valve during retrograde flow.
摘要翻译：用于植入患者的瓣膜（120）包括包括圆柱形形状的近侧区域（130）和具有大致矩形形状的远侧区域（170），其包括相对的平坦表面（172,174），所述相对平坦表面由较窄的平坦侧面（175a，175b）。锥形区域（150）设置在近端区域和远端区域之间，其中锥形区域包括两个相对的平坦表面（152,154），其过渡到远端区域的相对的平坦表面。锥形区域的相对的平坦表面相对于近端区域和远端区域成一定角度。在阀的远端处的相对的平坦表面允许流体在顺行流动期间流过其中，并且通常彼此相邻，以在逆行流动期间抑制通过阀的血液流动。可选地，至少一个加强构件（185）可以联接到阀，以防止在逆行流动期间阀的脱垂。

6. 发明公开

EP2517671A2 Apparatus for facilitating deployment of an endoluminal prosthesis 有权转让
标题翻译： Vorrichtung zurErmöglichungdes Einsetzens einer endoluminalen Prothese
公开(公告)号：EP2517671A2
公开(公告)日：2012-10-31
申请号：EP12164809.1
申请日：2012-04-19
申请人： Greenberg, Roy K. , West, Karl J. , Resch, Timothy A. , Roeder, Blayne A.
发明人： Greenberg, Roy K. , West, Karl J. , Resch, Timothy A. , Roeder, Blayne A.
IPC分类号： A61F2/06 , A61F2/84
CPC分类号： A61F2/07 , A61F2/06 , A61F2/82 , A61F2/86 , A61F2/89 , A61F2/95 , A61F2/954 , A61F2/962 , A61F2002/061 , A61F2002/072 , A61F2002/075 , A61F2002/821 , A61F2002/826 , A61F2002/9665 , A61F2220/0075 , A61F2230/0091 , A61F2250/0007 , A61F2250/0017 , A61F2250/0018 , A61F2250/0039
摘要： A system for facilitating deployment of an endoluminal prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. A wire segment may include a proximal portion positioned proximal of the proximal end opening and a distal portion positioned distal of the distal end opening. The wire segment extend through the fenestration and through the lumen of the branch in a preloaded configuration.
摘要翻译：用于促进内腔假体的展开的系统可以包括主管状移植物体，其包括近端开口，远端开口，内腔和侧壁。分支可以从侧壁延伸并且可以包括第一端部开口，第二端部开口和内腔。开窗可以设置在侧壁中并且定位在分支的第二端部开口的远侧。线段可以包括位于近端开口的近侧的近端部分和位于远端开口远端的远端部分。线段以预加载的配置延伸穿过开窗并通过分支的内腔。

7. 发明公开

EP2489331A2 Stent structures for use with valve replacement 有权转让
标题翻译： Stentstrukturen zur Verwendung mit Klappenersatz
公开(公告)号：EP2489331A2
公开(公告)日：2012-08-22
申请号：EP11275139.1
申请日：2011-11-04
申请人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
发明人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2220/0016 , A61F2230/0019 , A61F2230/0078
摘要： A medical device for implantation in a patient comprises a stent (20) and a valve (120). The stent (20) comprises a proximal region (30) comprising a cylindrical shape having a first outer diameter when the stent is in an expanded state, and a distal region (70) comprising a cylindrical shape having a second outer diameter when the stent is in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve (130) is at least partially positioned within the proximal region of the stent, and the distal region (140) of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.
摘要翻译：用于植入患者的医疗装置包括支架（20）和阀（120）。所述支架（20）包括近端区域（30），所述近端区域（30）包括当所述支架处于膨胀状态时具有第一外径的圆柱形形状，以及远端区域（70），当远端区域（70）包括具有第二外径的圆柱形状，处于扩张状态。第二外径大于第一外径。阀（130）的近侧区域至少部分地定位在支架的近侧区域内，并且阀的远侧区域（140）至少部分地定位在支架的锥形和远端区域之一内。当植入时，支架的近侧区域和瓣膜的近侧区域与天然瓣膜对准，并且瓣膜的远端区域与天然瓣膜远离间隔开。

8. 发明申请

WO2012051532A3 STENT-GRAFT SYSTEMS 审中-公开
标题翻译： STENT-GRAFT系统
公开(公告)号：WO2012051532A3
公开(公告)日：2012-12-13
申请号：PCT/US2011056365
申请日：2011-10-14
申请人： COOK MEDICAL TECHNOLOGIES LLC , CHUTER TIMOTHY A M , BROCKER DAVID , DIERKING WILLIAM K , LEEWOOD ALAN R , ROEDER BLAYNE A , CHARLEBOIS STEVEN J , SWIFT RICHARD A , GOPALAKRISHNAMURTHY SHARATH , HUSER MATTHEW S
发明人： CHUTER TIMOTHY A M , BROCKER DAVID , DIERKING WILLIAM K , LEEWOOD ALAN R , ROEDER BLAYNE A , CHARLEBOIS STEVEN J , SWIFT RICHARD A , GOPALAKRISHNAMURTHY SHARATH , HUSER MATTHEW S
IPC分类号： A61F2/06 , A61F2/82 , A61F2/86
CPC分类号： A61F2/89 , A61F2/07 , A61F2/848 , A61F2/852 , A61F2/856 , A61F2/915 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/826 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91541 , A61F2210/0014 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/006
摘要： Various stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system (800) comprises proximal (802) and distal (822) components, each comprising a graft (805, 825) having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component comprises a proximal stent (804) having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices greater than the radius of H is curvature of at least one of the distal apices. The distal component comprises a proximal z- stent (830a) coupled to the graft (825), where the proximal end of the graft comprises at least a scallop (845) formed therein that generally follows the shape of the proximal z- stent. Further, the distal component may comprise at least one z- stent (834) coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.
摘要翻译：公开了用于治疗医疗状况的各种支架移植物系统。在一个实施方案中，示例性支架移植物系统可用于胸主动脉瘤的血管内治疗。支架移植系统（800）包括近端（802）和远侧部件（822），每个部件包括具有近端和远端的移植物（805,825），其中在展开时，近端和远端部件至少部分地彼此重叠以在其间提供流体通道。近端部件包括近端支架（804），其具有通过多个大体上直的部分连接的多个近端和远端顶点，其中近端顶点中的至少一个的曲率半径大于H的半径为曲率至少一个远端顶点。远侧部件包括联接到移植物（825）的近端支架（830a），其中移植物的近端包括至少形成在其中的扇形齿（845），其大致遵循近端z-支架的形状。此外，远侧部件可以包括联接到移植物的远端并从其远端延伸的至少一个z支架（834），其减少远侧部件的近端迁移。

9. 发明申请

WO2010132597A1 EXPANDABLE STENT COMPRISING END MEMBERS HAVING AN INTERLOCKING CONFIGURATION 审中-公开
标题翻译：包含具有互锁配置的终端成员的可扩展性
公开(公告)号：WO2010132597A1
公开(公告)日：2010-11-18
申请号：PCT/US2010/034594
申请日：2010-05-12
申请人： MED INSTITUTE, INC. , ROEDER, Blayne, A. , KIM, Seoggwan , SWIFT, Richard, A.
发明人： ROEDER, Blayne, A. , KIM, Seoggwan , SWIFT, Richard, A.
IPC分类号： A61F2/90
CPC分类号： A61F2/91 , A61F2002/9522 , A61F2230/0054 , A61F2250/0098
摘要： An expandable stent (200) for use in a body vessel comprises a thin- walled tubular framework (205) including two or more circumferentially adjacent end members (210) extending in a longitudinal direction from an end of the framework. In a delivery configuration of the tubular framework, the end members have an interlocking configuration. Each end member has a first interlocking side (235) and a second interlocking side (240), where the first interlocking side has a circumf erentially directed protrusion (225) and the second interlocking side has a circumferentially directed recess (230). The protrusion of a first end member mates with the recess of a second end member. In an expanded configuration of the tubular framework, the end members are disengaged from the interlocking configuration. Each end member may be an eyelet (215) including an opening for a radiopaque rivet. A method of preparing the expandable stent for delivery into a body vessel is also described.
摘要翻译：用于身体容器的可扩张支架（200）包括薄壁管状框架（205），其包括沿框架的端部在纵向方向上延伸的两个或更多个周向相邻的端部构件（210）。在管状框架的输送构造中，端部构件具有互锁构造。每个端部构件具有第一互锁侧（235）和第二互锁侧（240），其中第一互锁侧具有圆周指向的突起（225），并且第二互锁侧具有周向定向的凹部（230）。第一端构件的突出部与第二端构件的凹部配合。在管状框架的扩展构造中，端部构件与互锁构造脱离。每个端部构件可以是包括用于不透射线的铆钉的开口的孔眼（215）。还描述了制备用于输送到体内容器中的可扩张支架的方法。

10. 发明申请

WO2010077808A1 BARB FOR ANCHORING AN IMPLANTABLE MEDICAL DEVICE WITHIN A BODY VESSEL 审中-公开
标题翻译：用于在身体血管中锚定可植入医疗装置的棒
公开(公告)号：WO2010077808A1
公开(公告)日：2010-07-08
申请号：PCT/US2009/067848
申请日：2009-12-14
申请人： MED INSTITUTE, INC. , LEEWOOD, Alan, R. , YANG, Shuo , DIERKING, William, K. , SWIFT, Richard, A. , ROEDER, Blayne, A.
发明人： LEEWOOD, Alan, R. , YANG, Shuo , DIERKING, William, K. , SWIFT, Richard, A. , ROEDER, Blayne, A.
IPC分类号： A61F2/02 , A61F2/06
CPC分类号： A61F2/02 , A61F2/07 , A61F2/848 , A61F2002/8483 , A61F2220/0016
摘要： A barb for anchoring an implantable medical device to a body vessel comprises a thin-walled body portion for engagement with a structural element of an implantable medical device and a penetrating element extending from the body portion. The body portion has a longitudinal axis. The penetrating element includes a tip portion for anchoring into tissue and a base portion between the tip portion and the body portion. In a deployed configuration of the barb, the base portion curves away from the longitudinal axis at a first curvature and the tip portion curves toward the longitudinal axis at a second curvature which is opposite in sign from the first.
摘要翻译：用于将可植入医疗装置固定到体内容器的倒钩包括用于与可植入医疗装置的结构元件和从身体部分延伸的穿透元件接合的薄壁主体部分。主体部分具有纵向轴线。穿透元件包括用于锚定到组织中的尖端部分和在顶端部分和主体部分之间的基部。在倒钩的展开构造中，基部以第一曲率远离纵向轴线弯曲，并且尖端部分以与第一曲面相反的第二曲率朝向纵向轴线弯曲。

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